Impact of Timing the Combination of Radiotherapy and PD-1 Inhibitors on Outcomes in Patients with Hepatocellular Carcinoma by Zhong L, Peng W, Sun J, Luo Y, Sheng H, Wu Y, Zhou T, Zhou C, Cao C

“…This study aimed to evaluate and compare the efficacy and treatment-related adverse events (TRAEs) of synchronously administered radiotherapy and programmed cell death protein (PD)-1 inhibitors and sequential administration in patients with HCC.Patients and Methods: We retrospectively enrolled 67 patients with HCC who were undergoing liver radiotherapy and PD-1 inhibitor therapy at two medical centers between July 2017 and April 2023. …”
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Utilizing Hip Abduction Strength to Body-Weight Ratios in Return to Sport Decision-Making After ACL Reconstruction by Steven Higbie, Jacquelyn Kleihege, Brian Duncan, Walter R. Lowe, Lane Bailey

“… # Results Of the 528 enrolled patients, 364 (68.9%) demonstrated a low strength to BW ratio. …”
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Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study by Venus Mirzaei, Jeanne Wolstencroft, Georgia Lockwood Estrin, Eleanor Buckley, Shermina Sayani, Panos Katakis, Reena Anand, Tessa Squire, Eleanor Short, Paige Frankson, David Skuse, Michelle Heys

“…As of November 2024, we had enrolled 57 participants to the pilot study and 12 to the qualitative substudy. …”
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Effect of COVID-19 Lockdown on Alcohol Consumption Among the Youths in Kampala, Uganda. A Cross-Sectional Study by Namiiro AM, Audo R, Nannungi CD, Pitua I, Kiberu D, Talemwa P, Mujuni E, Lwesabula A, Ageimo P, Khaukha AZ, Kuol MJ, Egaru L, Koire M, Ssewante N

“…Frequent was defined as six or more drinks a week.Results: We enrolled 381 participants in the study with a mean age of 26± 4.6 years. …”
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Factors influencing survival outcomes in patients with stroke at three tertiary hospitals in Zimbabwe: A 12-month longitudinal study. by Farayi Kaseke, Lovemore Gwanzura, Cuthbert Musarurwa, Elizabeth Gori, Tawanda Nyengerai, Timothy Kaseke, Aimee Stewart

“…<h4>Results</h4>In our study, 188 stroke patients were enrolled at baseline. However, 51 patients were excluded from the analysis due to either missing information or loss to follow-up. …”
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Mortality Risk Prediction in Patients With Antimelanoma Differentiation–Associated, Gene 5 Antibody–Positive, Dermatomyositis–Associated Interstitial Lung Disease: Algorithm Development and Validation by Hui Li, Ruyi Zou, Hongxia Xin, Ping He, Bin Xi, Yaqiong Tian, Qi Zhao, Xin Yan, Xiaohua Qiu, Yujuan Gao, Yin Liu, Min Cao, Bi Chen, Qian Han, Juan Chen, Guochun Wang, Hourong Cai

“… BackgroundPatients with antimelanoma differentiation–associated gene 5 antibody–positive dermatomyositis–associated interstitial lung disease (anti-MDA5+DM-ILD) are susceptible to rapidly progressive interstitial lung disease (RP-ILD) and have a high risk of mortality. …”
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Impact of Pre-existing Type 2 Diabetes Mellitus and Cardiovascular Disease on Healthcare Resource Utilization and Costs in Patients With COVID-19 by Chi Nguyen, Christopher L. Crowe, Effie Kuti, Bonnie Donato, Rachel Djaraher, Leo Seman, Nancy Graeter, Thomas P. Power, Rinku Mehra, Vincent J. Willey

“…Patients with COVID-19 were identified between March 1, 2020, and May 31, 2021, and followed from first diagnosis or positive lab test to the end of health plan enrollment, end of study period, or death. Patients were assigned one of 3 cohorts: pre-existing T2DM+CVD, T2DM only, or neither T2DM/CVD. …”
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Comparative- and Cost-Effectiveness Research Determining the Optimal Intervention for Advancing Transgender Women With HIV to Full Viral Suppression (Text Me, Alexis!): Protocol fo... by Cathy J Reback, Thomas Blue, Ali Jalali, Raphael Landovitz, Michael J Li, Raymond P Mata, Danielle Ryan, Philip J Jeng, Sean M Murphy

“…ResultsRecruitment began on April 10, 2024, and the first participant was enrolled on April 11, 2024. Data collection is expected to be completed in July 2027. …”
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Development and validation of an explainable machine learning model for mortality prediction among patients with infected pancreatic necrosisResearch in context by Caihong Ning, Hui Ouyang, Jie Xiao, Di Wu, Zefang Sun, Baiqi Liu, Dingcheng Shen, Xiaoyue Hong, Chiayan Lin, Jiarong Li, Lu Chen, Shuai Zhu, Xinying Li, Fada Xia, Gengwen Huang

“…Methods: We performed a prospective cohort study of 344 patients with IPN consecutively enrolled from a large Chinese tertiary hospital from January 2011 to January 2023. …”
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Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis by Sandra M Herrmann, Riley Fadden, Ryan J Sullivan, Kerry L Reynolds, Harish Seethapathy, Meghan E Sise, Shruti Gupta, Alexandra-Chloe Villani, Qiyu Wang, Daiana Moreno, Destiny Harden, R Neal Smith, Ivy A Rosales, Robert B Colvin, Sarah Chute, Lynn D Cornell, Nancy J Yang, Sara Barmettler, Sophia Wells, Jocelyn Farmer

“…By peripheral blood flow cytometry analysis, lower absolute CD8+T cells, CD45RA+CD8+ T cells, memory CD27+B cells, and expansion of plasmablasts were prominent features of ICI-nephritis compared with ICI-treated controls. Gene expressions for IL2RA, IL-2 signaling, and T cell receptor signaling in the kidney tissue with ICI-nephritis were significantly higher compared with controls.Conclusion Elevated sIL-2R level and flow cytometric markers of both B and T cell dysregulation may aid the diagnosis of ICI-nephritis.…”
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Cross-sectional Study of EMG and EMG Rise During Fast and Slow Hamstring Exercises by Kasper Krommes, Markus Due Jakobsen, Thomas Bandholm, Lars Louis Andersen, Mette Zebis, Anthony Shield, Per Hölmich, Kristian Thorborg

“… # Methods Out of 28 participants enrolled, the final sample included 23 recreationally active male participants who attended a session for determining RM (repetition maximum) to establish loading (8 and 16RM for Hamstring Catches, and 8, 16 and 24RM for Leg Curl) and to familiarize themselves with the three different exercises (Nordic Hamstring, Leg Curl and Hamstring Catch), and a testing session >4 days after during which EMG data were collected during 3 repetitions of each exercise performed in a random order…”
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Sensory acceptability of buffalo meat compared to beef by Luis A. de la Cruz-Cruz, Cristian Larrondo-Cornejo, Patricia Roldán-Santiago, René Rodríguez-Florentino

“…The samples were evaluated by 76 students (non-trained panelists) enrolled in the food quality and safety course of the Veterinary Medicine and Zootechnics career, UVM. …”
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Evaluación técnico-económica del uso de biopolímeros para el tratamiento de aguas residuales de curtiembres. by Nickole Basurto-Flores, Nataly Medina-Guerrero

“…La concentración de parámetros de sólido sedimentable y aceites y grasas se encontró dentro de los VMA. Sin embargo, para sulfuros, DBO y DQO no se cumplió. …”
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Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study by Kim Dunleavy, Heidi Liss Radunovich, Jason M Beneciuk, Boyi Hu, Yang Yang, Janeen McCormick Blythe, Kelly K Gurka

“…The design, creation, and editing of English and Spanish videos was completed in June 2024 after comprehensive formative evaluation. Enrollment began in June 2024 with anticipated completion in 2027. …”
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Impact of alcohol drinking and tobacco smoking on the drug-resistance of newly diagnosed tuberculosis: a retrospective cohort study in Shandong, China, during 2004–2020 by Yi-Fan Li, Yao Liu, Qi Fu, Wan-mei Song, Jin-yue Liu, Qian-yun Zhang, Ting-ting Xu, Shi-jin Li, Qi-qi An, Si-qi Liu, Huai-chen Li, Ning Ning Tao, Xue-han Zhu, Chun-bao Yu, Jihua Dong

“…We described the drug-resistant profiles, clinical factors and calculated the ORs of different drug-resistance among G1, G2, G3, compared with G0 through univariate and multivariate logistics regression models.Results Of the 7996 TB cases enrolled, the proportions of G1, G2, G3 and G0 were 8.25%, 3.89%, 16.46% and 71.40%, respectively. …”
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Susceptibility profile and associated factors of urinary tract infections among women with established preterm labor delivering at a tertiary teaching hospital in Eastern Uganda: a... by Abdirizak Ahmed Ifrah, Marie Pascaline Sabine Ishimwe, Carlos Antonio Batista Cedeño, Eilu Emmanuel, Theoneste Hakizimana

“…Using a consecutive sampling method, 385 pregnant women were enrolled until the desired sample size was reached. …”
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The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired p... by Huamei Zhou, Xuelei Zhu, Yi Zhang, Wenjuan Xu, Shiqun Li

“…AST/ALT also predicted outcomes for all the CAP patients enrolled (OR = 1.771, 95% CI, 1.231–2.549, p = 0.002). …”
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The prevalence of cancer in patients with multiple sclerosis (MS) who received rituximab: a systematic review and meta-analysis by O. Mirmosayyeb, V. Shaygannejad, N. Ebrahimi, H. Ghoshouni, M. Ghajarzadeh

“…Totally, 15599 patients were enrolled while 133 cancers were detected.The pooled prevalence of cancer in MS patients under treatment with rituximab is 1in 100,000 (I2 = 99.9%, p < 0.001). …”
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A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-brain rad... by Huaqu Zeng, MinZhi Zhong, Zongyou Chen, Shukui Tang, Zunbei Wen

“…ObjectiveThe aim of this study was to investigate the dosimetric differences between non-coplanar volumetric modulated arc therapy (VMAT) and non-coplanar fixed-field intensity-modulated radiotherapy (IMRT) in hippocampus-avoidance whole-brain radiation therapy with a simultaneous integrated boost (HA-WBRT+SIB) for brain metastases using the Monaco treatment planning system (TPS).MethodA total of 22 patients with brain metastases were retrospectively enrolled. Two radiotherapy treatment plans were designed for each patient: non-coplanar VMAT and non-coplanar fixed field IMRT. …”
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Identificación del origen genético de un rodal semillero implantado de Nothofagus obliqua a través del análisis de dos regiones intergénicas de ADN de cloroplasto by M.M. AZPILICUETA, P. MARCHELLI, A. G. APARICIO, M. J. PASTORINO

“…De esta manera es posible prescribir el uso de la semilla de este rodal, no solo en acciones de plantación comercial fuera del área de distribución de la especie, sino también en actividades de restauración de bosques de N. obliqua dentro de la cuenca Lácar. Asimismo, se pudieron establecer asociaciones directas entre los haplotipos hallados por la técnica de PCR-RFLP (utilizada en estudios previos) y la secuenciación (utilizada en el presente estudio) para ambas regiones intergénicas del ADN de cloroplasto analizadas, lo que permitirá continuar usando el método de secuenciación en futuros análisis sin perder la homología con la información obtenida por medio del método más antiguo.…”
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