IS26-mediated cointegration generates a plasmid co-harbouring blaIMP-4 and blaKPC-2 in Klebsiella pneumoniae by Jiawei Zhou, Xiaohua Meng, Shujun Ni, Yunxing Yang, Qiong Zhang, Lingjiao Wu, Qiong Chen

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Exploitation of enhanced prime editing for blocking aberrant angiogenesis by Xionggao Huang, Wenyi Wu, Hui Qi, Xiaohe Yan, Lijun Dong, Yanhui Yang, Qing Zhang, Gaoen Ma, Guoming Zhang, Hetian Lei

“…Methods: An advanced PE system (referred to as PE6x) was established within two lentiviral vectors, with one carrying an enhanced PE guide RNA and a canonical Cas9 nickase fused with an optimized reversal transcriptase, and the other conveying a nicking guide RNA and a DN-MLH1 to improve PE efficiency. Dual non-integrating lentiviruses (NILVs) produced with the two lentiviral PE6x vectors were then employed to create a mutation of VEGFR2 T17967A by editing the Mus musculus VEGFR2 locus in vitro and in vivo, leading to generation of a premature stop codon (TAG, K796stop) to produce DN-VEGFR2, to interfere with the wild type VEGFR2 which is essential for angiogenesis. …”
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Evaluating municipal solid waste management efficiency in Iceland: A data envelopment analysis of socioeconomic and geographic influences by Guðmundur Kristján Óskarsson, Sveinn Agnarsson, Brynhildur Davíðsdóttir

“…This study aims to evaluate the efficiency of municipal solid waste management in Iceland, focusing on the factors influencing waste generation and recycling rates. …”
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Thermodynamic, economic, and environmental evaluation of internal combustion engine exhaust gas-driven Organic Rankine cycles for power generation and desalination by Mohammad Waqas Chandio, Laveet Kumar, Abdul Ghafoor Memon, Mohamed M. Awad

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Stabilizing Environmental Conditions for Improved Biogas Generation: A Comparative Analysis of Above-ground and Underground Plastic Digester in Fed-batch Systems by H. Usman Muhammad, M. Sulaiman, M. Sulaiman Yahaya, S. Saminu

“…When comparing above-ground and underground setups, it was found that the latter significantly improves biogas generation efficiency by keeping the surrounding temperature at 34°C, speeds up biogas production, and produces noticeably higher pressure readings—up to 1200 kPa, which is more than twice as high as in non-buried setups. …”
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A Quad-Band Stacked Hybrid Ambient RF-Solar Energy Harvester With Higher RF-to-DC Rectification Efficiency by Sunanda Roy, Jun-Jiat Tiang, Mardeni Bin Roslee, Md Tanvir Ahmed, M. A. Parvez Mahmud

“…The harmonic balance of EM solver is used to design and maximize the RF- to - DC rectification efficiency with the combination of the antenna and the solar cell. …”
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A compact dual-band reconfigurable antenna with metamaterial for IoT applications by Abdullah Hasan Ali, Jamal Mohammed Rasool, Ali Kadhum Abd, Md. Shabiul Islam, Mohamed Ouda, Mohamad A. Alawad, Mohammad Tariqul Islam

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Improving the robustness and efficiency of cell sheet protocol for breast cancer induction in animal model: A Geltrex plus Gelatin approach. by Alaa T Alshareeda, Nada Albarakati, Yasser Alshawakir, Ayidah Alghuwainem, Batla S Al-Sowayan, Abdul Latif Khan, Abdullah Almubarak, Sarah Al-Maiman, Ahood Al Sayed, Nur Khatijah Mohd Zin, Amal S Alhamid

“…<h4>Results</h4>The novel protocol enhanced cell sheet transplant efficiency by providing scaffold support and temporary adhesion. …”
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Nanopore-based targeted next-generation sequencing (tNGS): A versatile technology specialized in detecting low bacterial load clinical specimens. by Chen Yang, Weiwei Gao, Yicheng Guo, Yi Zeng

“…Nanopore-based targeted next-generation sequencing (tNGS) offers advantages such as convenience, efficiency, and long-read sequencing, making it a commonly used method for mycobacteria identification.…”
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V2Va +: An Efficient SystemVerilog &#x0026; Verilog-to-Verilog-A Translator for Accelerated Mixed-Signal Simulation by Chao Wang, Yicong Shao, Jiajie Huang, Wangzilu Lu, Zhiwen Gu, Longfan Li, Yuhang Zhang, Jian Zhao, Wei Mao, Yongfu Li

“…The V2Va + translation tool comprises two integral components: a parser function, tasked with extracting information from SystemVerilog and Verilog files, and a Verilog-A generator, responsible for generating corresponding Verilog-A code. …”
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Precise Editing of chNHE1 Gene via CRISPR/Cas9 Generates ALV-J-Resistant Chicken Primordial Germ Cell by Xinyi Zhou, Ruyu Liao, Min Tan, Yu Zhang, Haiwei Wang, Keshan Zhang, Qigui Wang, Xi Lan

“…The constructed dual lentiviral vector efficiently targeted the W38 site. PGCs isolated from 5.5- to 7-day-old chicken embryos were suitable for in vitro gene editing. …”
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Study and Characterization of New KPIs for Measuring Efficiency in Urban Loading and Unloading Zones Using the OEE (Overall Equipment Effectiveness) Model by Angel Gil Gallego, María Pilar Lambán, Jesús Royo Sánchez, Juan Carlos Sánchez Catalán, Paula Morella Avinzano

“…The use of LUZs in urban environments is a critical factor for ensuring efficient vehicle mobility in cities. Poor utilisation of these zones can generate negative externalities, such as double parking or illegal occupation of pedestrian crossings or garage doors. …”
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Design of Radix-8 Unsigned Bit Pair Recoding Algorithm-Based Floating-Point Multiplier for Neural Network Computations by J. Jean Jenifer Nesam, S. Sankar Ganesh

“…The neural network computations for Artificial Intelligence (AI) applications demand high speed, low power and area-efficient Floating-Point (FP) multiplication. In this work, we propose an efficient unsigned Bit Pair Recoding (BPR) algorithm for area, power, and speed improved FP unsigned mantissa multiplication. …”
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PERFORMANCE ANALYSIS OF THE EU MEMBER STATES' TAX SYSTEMS by Mariana-Luminita COMAN (LINTA)

“…The design of a tax system influences investors' decisions, it can create incentives for investment and consumption or it can generate implications for negative externalities. The efficiency of a tax system is evaluated in terms of the high degree of tax revenue collection, in terms of low costs for taxpayers and the tax administration. …”
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A systematic review and meta-analysis of efficacy and safety of compound glycyrrhizin combined with second-generation non-sedated antihistamine for the treatment of chronic urticar... by Sijue Chen, Wei Cao, Xianjun Xiao, Lu Wang, Renhong Wan, Zihao Zou, Qian Yang, Ying Li

“…Significant differences were noted in rate of total efficiency (n = 2649, RR = 1.36, 95%CI:1.30–1.43, p < 0.00001), cure (n = 2649, RR = 1.54, 95%CI:1.42–1.66, p < 0.00001) and recurrence (n = 446, RR = 0.34, 95%CI:0.20–0.58, p < 0.00001) between the combination of CG with second-generation non-sedated antihistamine and antihistamine monotherapy. …”
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Real-world pathogen diagnosis in critically ill infected children: A retrospective study using metagenomic next-generation sequencing with different enrichment strategies by Huili Shen, Xiaolei Zhang, Junfeng Xu, Weike Ma, Weiming Chen, Yixue Wang, Caiyan Zhang, Panpan Fan, Xuemei Zhu, Liming He, Huiyuan Yan, Meili Shen, Guoping Lu, Gangfeng Yan

“…Abstracts: Background: Study on the clinical pathogen diagnosis in large cohort of critically ill children using metagenomic next-generation sequencing (mNGS) with different enrichment strategies has been limited. …”
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Hi-TARGET: a fast, efficient and versatile CRISPR type I-B genome editing tool for the thermophilic acetogen Thermoanaerobacter kivui by Angeliki Sitara, Rémi Hocq, Alexander Jiwei Lu, Stefan Pflügl

“…Conclusions The CRISPR-based genome editing tool Hi-TARGET developed for T. kivui can be used for scarless deletion, insertion, point mutation and gene knock-down, thus fast-tracking the generation of industrially-relevant strains for the production of carbon-negative chemicals and fuels as well as facilitating studies of acetogen metabolism and physiology.…”
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Insights into the transformations, antimicrobial activity, and degradation efficiency of a representative carbapenem antibiotic by high-frequency ultrasound hybridized with the (ph... by Efraím A. Serna-Galvis, Kevin P. Celis-Llamoca, Ingrit E. Collantes-Díaz, Ricardo A. Torres-Palma, Jessica I. Nieto-Juárez

“…Carbapenems are potent antibiotics that reach sewage systems and then the environment, causing negative impacts. Thus, research on degrading processes to limit the carbapenem discharge in sewage systems is needed. …”
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Financial repression policy: Latin America and Spain’s lessons for Russia by Farid Akhmed Abu Bakr

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The Impact of Risk Management Efficiency on Organizational Performance in State-Owned Enterprises and the Mediating Ef-fect of Supply Chain Maturity: Evidence from Morocco by Benkirane Kawtar, Benazzi Khadija

“…Concretely, the formalization of risk management practices is supported, while integrated risk management shows a negative effect on the organizational performance of public offices, contradicting our expectations, which reflects on the one hand the weak relationship between the two variables with a negative student T of -6.040. …”
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