Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells by Viktor Glaser, Christian Flugel, Jonas Kath, Weijie Du, Vanessa Drosdek, Clemens Franke, Maik Stein, Axel Pruß, Michael Schmueck-Henneresse, Hans-Dieter Volk, Petra Reinke, Dimitrios L. Wagner

“…Combining Cas12a Ultra for CAR knock-in and a Cas9-derived base editor enables the efficient generation of triple-edited CAR T cells with a translocation frequency comparable to unedited T cells. …”
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Multiclass Sentiment Analysis of Electric Vehicle Incentive Policies Using IndoBERT and DeBERTa Algorithms by Muhammad Bayu Nugroho, Akhmad Khanif Zyen, Nur Aeni Widiastuti

“…The electric vehicle (EV) incentive policy in Indonesia has generated various public reactions, particularly on social media platforms. …”
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Anomaly classification in IIoT edge devices by Danny Alexandro Múnera-Ramírez, Diana Patricia Tobón-Vallejo, Martha Lucía Rodríguez-López

“…A multi-class classifier that detects events, failures, or attacks is much more efficient than a simple binary classifier, as it relieves a human operator of the task of identifying anomaly causes, thereby avoiding wasted time that could compromise process performance and security. …”
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Bacterial profile and antibiotic susceptibility pattern of adult lower respiratory tract infections in Colombo, Sri Lanka by Nadeesha Amarasinghe, Muthulingam Athavan, Deepal Jayamanne, Yamuna Rajapakshe, Aflah Sadikeen, Kirthi Gunasekara, Amitha Fernando, Lilani Karunanayake

“…Co-amoxyclav, 3rd generation cephalosporins, quinolones and all second line antibiotics tested were the most efficient antibiotics in treatment of LRTIs, differently from ampicillin, erythromycin and penicillin that were not efficient antibiotics in treating this disease in our locality.…”
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An eleven level single source switched capacitor boost inverter with reduced component stress and limited inrush current by Alireza Poulad, Majid Hosseinpour, Mojtaba Najafi, Abdolrasool Ghasemi

“…Abstract One of the most important advanced and efficient technologies in converting DC electrical energy to AC is switched-capacitor multilevel inverters with reduced charging current, which enable output voltage boosting. …”
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Investigation of Aloe vera mediated ZnO-β-CD nanocomposite for photocatalysis and antimicrobial applications by Arti Hadap, Vishal R. Panse, Serhii Tereshchuk

“…Due to unique bandgap (3.0 eV) and enhanced electron-hole recombination dynamics, the newly synthesized nanocomposite can not only able to demonstrate the efficient photocatalytic degradation of methylene blue (MB) dye by achieving complete discoloration at 6 pH within 160 min under visible light—a significant improvement over previously reported ZnO-based system, but furthermore, it also strongly combatted by the antibacterial activity against Gram-positive bacteria S. aureus, gram-negative bacteria E. coli, and the fungus strain A. niger. …”
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FAHPBEP: A Fuzzy Analytic Hierarchy Process Framework in Text Classification by Razieh Asgarnezhad, Sayed Monadjemi, MohammadReza Soltanaghaei

“…With the availability of websites and the growth of comments, reviews of user-generated content published on the Internet. Sentiment Classification is one of the most common problems in text mining, which applies to categorize reviews into positive and negative classes. …”
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Selective evolution of methanogenic communities by β-lactam antibiotics promotes methane production by Yuting Zhe, Huaigang Cheng, Danjing Ding, Yueyue He, Zhuohui Ma, Jing Shen

“…In addition, amoxicillin degrades rapidly within the system, resulting in minimal negative environmental impact. This work provides a promising and eco-friendly approach to optimize biomethane production, offering a viable and sustainable solution for energy generation from waste.…”
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Potential public health impacts of gonorrhea vaccination programmes under declining incidences: A modeling study. by Lin Geng, Lilith K Whittles, Borame L Dickens, Martin T W Chio, Yihao Chen, Rayner Kay Jin Tan, Azra Ghani, Jue Tao Lim

“…VoD had a smaller impact (12.04% averted cases (95% CrI: 7.12%-15.00%)), but was three times more efficient than VoA in terms of averted cases per dose. …”
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Synoptic reporting accuracy for computed tomography pulmonary arteriography among patients suspected of pulmonary embolism by Isabela A. Woller, Scott C. Woller, Scott M. Stevens, James F. Lloyd, Karen E. Conner, Benjamin H. Gordon, Greg L. Snow, Peter Jones, Joseph R. Bledsoe

“…Abstract Background Structured reporting is an efficient and replicable method of presenting diagnostic results that eliminates variability inherent in narrative descriptive reporting and may improve clinical decisions. …”
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Experiences and Expectations of Immigrant and Nonimmigrant Older Adults Regarding eHealth Services: Qualitative Interview Study by Maedeh Ghorbanian Zolbin, Sari Kujala, Isto Huvila

“… BackgroundThe emergence of eHealth services could contribute to improving individuals’ quality of life by optimizing effective and efficient care. However, various challenges might limit some older adults’ use of eHealth services. …”
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Nitric Oxide‐Releasing Nanoscale Metal‐Organic Layer Overcomes Hypoxia and Reactive Oxygen Species Diffusion Barriers to Enhance Cancer Radiotherapy by Yuxuan Xiong, Jinhong Li, Xiaomin Jiang, Wenyao Zhen, Xin Ma, Wenbin Lin

“…Under X‐ray irradiation, SNAP/MOL efficiently generates superoxide anion (O2−.) and releases nitric oxide (NO) in a spatio‐temporally synchronized fashion. …”
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Rice Leaf Disease Image Enhancement Based on Improved CycleGAN by YAN Congkuan, ZHU Dequan, MENG Fankai, YANG Yuqing, TANG Qixing, ZHANG Aifang, LIAO Juan

“…Comparative experiments were conducted across multiple GAN models, enabling a thorough assessment of the proposed model's performance in generating rice disease images. Additionally, different attention mechanisms, including efficient channel attention (ECA), coordinate attention (CA), and CBAM, were individually embedded into the generator's residual module. …”
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Data-driven design of electrolyte additives supporting high-performance 5 V LiNi0.5Mn1.5O4 positive electrodes by Bingning Wang, Hieu A. Doan, Seoung-Bum Son, Daniel P. Abraham, Stephen E. Trask, Andrew Jansen, Kang Xu, Chen Liao

“…Abstract LiNi0.5Mn1.5O4 (LNMO) is a high-capacity spinel-structured material with an average lithiation/de-lithiation potential at ca. 4.6–4.7 V vs Li+/Li, far exceeding the stability limits of electrolytes. An efficient way to enable LNMO in lithium-ion batteries is to reformulate an electrolyte composition that stabilizes both graphitic (Gr) negative electrode with solid-electrolyte-interphase and LNMO with cathode-electrolyte-interphase. …”
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MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and Prognosis by Tereza Halkova, Romana Cuperkova, Marek Minarik, Lucie Benesova

“…The mechanism involves both positive and negative regulation of expression of protooncogenes and tumor suppressor genes. …”
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An evolutionary game theory-based machine learning framework for predicting mandatory lane change decision by Sixuan Xu, Mengyun Li, Wei Zhou, Jiyang Zhang, Chen Wang

“…Mandatory lane change (MLC) is likely to cause traffic oscillations, which have a negative impact on traffic efficiency and safety. There is a rapid increase in research on mandatory lane change decision (MLCD) prediction, which can be categorized into physics-based models and machine-learning models. …”
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Smartphone-based Monitoring and cognition Modification Against Recurrence of Depression (SMARD): An RCT of Memory Bias Modification Training vs. Cognitive Control Training vs. Atte... by N. Ikani, A. Tyborowska, N. Kohn, N. Günther, G J. Siegle, A. H. Schene, J. A. S. Vorstman, C. J. Harmer, M. J. Kas, J. N. Vrijsen, H. G. Ruhé

“…Negative memory bias (the tendency to better remember negative than positive events), negative attention bias (selective attention favoring mood-congruent information), and cognitive control deficits are important factors involved in the onset, maintenance, and recurrence of depressive episodes. …”
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Comparison of the Characteristics of Hydrochar and Torrefied-Char of Traditional Chinese Medicine Residues by Zhiqiang Xu, Wenyu Ren, Shiliang Wu, Rui Xiao

“…With the continuous reduction in fossil energy reserves and the increasingly prominent negative impacts on the environment, the search for sustainable alternative materials has become an urgent task. …”
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Relation of Muscles Coordination to the Major Degrees of Freedom in Three Upper Limb Motions by Morteza Farrokhnia, Seyyed Arash Haghpanah, Esmaeal Ghavanloo, Mohammad Taghi Karimi

“…After validation, dominant muscles in each phase of motion are identified through non-negative matrix factorization (NNMF) and inverse kinematics (IK) approaches. …”
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Trajectory analysis of Mythimna Loreyi migration into Korea using the HYSPLIT model by Juhyeong Han, Sunghoon Baek, Xue-Jing Wang, Chun-Sen Ma, Kwang-Hyung Kim

“…Abstract Migratory moth species have a negative impact on agriculture in Korea, causing economic crop losses for farming households. …”
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