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421
Developing the MyCancerGene Digital Health Portal to Improve Patients’ Understanding of Germline Cancer Genetic Test Results: Development, User, and Usability Testing Study
Published 2025-05-01“…ResultsIn surveys conducted in step 1, 90% of patients with positive results reported interest in a digital GHP, and over 75% of participants with variants of uncertain significance or uninformative negative results reported similar interest. The most frequently reported advantages among patients were increasing accessibility, convenience, and efficiency (103/224, 46%); keeping genetic information organized (54/224, 24.1%); and increasing or maintaining patient understanding of the information (38/224, 17%). …”
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422
Novel triple-target panels utilizing methylation-sensitive restriction enzyme-based quantitative PCR for detecting advanced cervical precancers and cancers among high-risk HPV-posi...
Published 2025-08-01“…All possible triple-target panels from these genes were generated by logistic regression models with repeated ten-fold cross-validation on a training set of 1223 women (180 CIN3 +; 1043 < CIN3). …”
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423
Smartphone-based Monitoring and cognition Modification Against Recurrence of Depression (SMARD): An RCT of Memory Bias Modification Training vs. Cognitive Control Training vs. Atte...
Published 2025-05-01“…Negative memory bias (the tendency to better remember negative than positive events), negative attention bias (selective attention favoring mood-congruent information), and cognitive control deficits are important factors involved in the onset, maintenance, and recurrence of depressive episodes. …”
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424
Worm-filter in the Recovery of Wastewater from the Commercial Activity of Hydrobiological Products
Published 2025-07-01“…The wastewater generated in these places has a high potential for contamination, which, if not properly treated, would have negative environmental impacts on the receiving body. …”
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425
Spectroscopic study of methylene blue photophysical properties in biological media
Published 2023-08-01“…In the investigated range of MB concentrations, the efficiency of singlet oxygen generation is rather low, because positively charged MB binds to negatively charged cell membranes, which leads to a change in the type of photodynamic reaction. …”
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426
PEDAGOGICAL VALUE OF THE COMMUNICATION AS A PROFESSIONAL ETHICAL PHENOMENON IN THE EDUCATION OF DENTISTS STUDENTS
Published 2018-03-01“…The communication system includes important educational relationships that promote the efficiency of education and training. In the pedagogical sphere the communication acquires significant functional and professional character. …”
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427
Evidence of a role for the F1 capsule of Yersinia pestis in enhancing transmission from mammals to fleas in a mouse model of bubonic plague
Published 2025-05-01“…Here, we show that F1-negative Δcaf mutants of Y. pestis are virulent in a mouse model but with a longer time to terminal disease. …”
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428
Development of FRET-based cap-snatching endonuclease assay
Published 2025-05-01“…ABSTRACT The order Bunyavirales consists of over 300 species of segmented, negative-strand RNA viruses. These viruses have a tri-segmented genome (S, M, and L segments) that encodes the nucleocapsid protein (N protein), glycoprotein precursor, and RNA-dependent RNA polymerase (RdRp), respectively. …”
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429
Adaptive Bayesian Nonparametric Regression via Stationary Smoothness Priors
Published 2025-03-01“…Relative to previous work adopting a similar approach that either employs a single global smoothing parameter or assumes that the smoothing process follows a random walk, the model considered here permits adaptive smoothing and imposes stationarity in the autoregressive smoothing process. An efficient Markov Chain Monte Carlo (MCMC) scheme for model estimation is fully described for this stationary case, and the performance of the method is illustrated in several generated data experiments. …”
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430
CONCEPT FORMATION OF ENTERPRISE SUSTAINABLE DEVELOPMENT
Published 2008-06-01“…However even having such economic situation the lost opportunity due to nonuse of the possibility to start change-over to products of new generation covers minimization of expenses achieved at the cost of efficient usage of obsolete technologies and worn-out equipment.…”
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431
AI-powered literature search: some observations and concerns
Published 2024-12-01“…The algorithms behind AI tools may inherently approve of a certain type of content or styles of writing, which can affect the summaries produced.7 This data and algorithmic bias may be problematic for seasoned researchers who need to understand the basis for the information being generated by these AI tools. A lack of understanding of the mechanisms and algorithms can negatively influence their ability to critically evaluate the relevance and reliability of the AI-generated outputs. …”
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432
Analysis of Artificial Intelligence Monopoly Issue and Related Solutions
Published 2025-01-01“…Although the organizational monopoly in the AI industry is more efficient in text and image generation and transmission in a vast and generative digital market, it still has some problems. …”
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433
Development and variability of soft winter wheat varieties in stress environmental conditions
Published 2014-04-01“…It is found that efficient development of generative organs is subject to variety bushing capacity, in particular at spring. …”
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434
Fundamentals of metric theory of real numbers in their $\overline{Q_3}$-representation
Published 2021-10-01“…In the paper we were studied encoding of fractional part of a real number with an infinite alphabet (set of digits) coinciding with the set of non-negative integers. The geometry of this encoding is generated by $Q_3$-representation of real numbers, which is a generalization of the classical ternary representation. …”
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435
Advancing sustainability in EDM: A brief review of eco-friendly dielectric fluids
Published 2025-04-01“…In EDM, material removal occurs as a result of intense heat generated by the movement of electrons from the negatively charged cathode to the positively charged anode. …”
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436
Large-Scale Electrosynthesis of Carbon Nano-Onions from CO2 as a Potential Replacement for Carbon Black
Published 2025-01-01“…Graphite and carbon black are major global commodities whose production generates substantial CO _2 emissions. Carbon nano-onions (CNOs), consisting of concentric graphene spheres with enhanced properties due to their unique morphology, represent a promising next-generation material. …”
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437
CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells
Published 2024-10-01“…In time-frames where the global EV distribution did not change between HER2-positive (SK-BR-3) or -negative (MDA-MB-231) breast cancer cell lines, the HER2 exposure in isogenic cells remarkably affected the tropism of heterologous EVs, demonstrating the specificity of antiHER2 EVs representing about 20% of secreted bulk vesicles. …”
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438
Study on the influencing factors of radial non-Darcy seepage of gas in CO2 fracturing boreholes
Published 2024-12-01“…CO2 fracturing, as a key technology to improve the gas extraction efficiency of low-permeability coal seams, has a core mechanism of injecting high-pressure CO2 into coal seams to induce the generation of a fracture network within the coal body, thus greatly improving the permeability of the coal seams. …”
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439
Research Progress on Selective Depolymerization of Waste Plastics to High-Quality Liquid Fuels
Published 2025-06-01“…Lifecycle assessments revealed that hybrid systems could achieve carbon-negative profiles when coupled with renewable energy. …”
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440
Support on four paws—does the integration of a therapy dog reduce anxiety and increase positive affect in spider phobics during in vivo exposure therapy?: study protocol for a para...
Published 2025-07-01“…However, despite high efficacy and efficiency, dissemination of exposure-based treatments is limited. …”
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