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Exploring microbial players for metagenomic profiling of carbon cycling bacteria in sundarban mangrove soils
Published 2025-02-01“…The findings emphasize the key role of microbial activity in preserving mangrove ecosystem health and resilience, highlighting the intricate interplay between microbial diversity, functional capabilities, and environmental factors.…”
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Genome-wide association analysis and KASP markers development for protein quality traits in winter wheat
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Evaluation of cellular and physiological alterations of cells from Mytilus galloprovincialis exposed to benzisothiazolinone
Published 2025-01-01“…Moreover, the cytoprotective mechanisms related to oxidative stress and detoxification were evaluated through the expression analysis by qPCR of key genes involved in these pathways. The most significant results obtained from these tests were the reduction of viability of haemocytes at T2 of exposure to B2, a decrease of vitality in DG cells exposed to B1 during the T1, the significant alteration in the phagocytosis activity, the upregulation of Cu/ZnSOD gene, the inhibition of the CYPY1 gene expression and upregulation of the Heat shock protein 70 (Hsp70) gene following the BIT exposure. …”
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Integration of single-cell and bulk RNA-sequencing data to construct and validate a signature based on NK cell marker genes to predict immunotherapy response and prognosis in color...
Published 2025-02-01“…Six key NK cell-related prognostic signature genes were obtained by univariate and LASSO regression analyses, including ADAM8, CTSD, CCL4, IL2RB, TTC38, and PLEK. …”
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Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set...
Published 2025-01-01“…Eventually, we developed a novel in silico antagonist screening platform (http://43.136.69.224:3838/wlab/) based on drug-target gene set enrichment analysis (dtGSEA version 2.0). …”
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Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets
Published 2025-02-01“…MiRNA-target network highlighted key genes such as PHF8, LCOR, SFT2D3, E2F1, and ESR1, which were found to be prognostic for patient survival. …”
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CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct t...
Published 2025-02-01“…These analyses revealed a sustained upregulation of a transcriptional profile of purinergic receptors and ectonucleotidases in cGVHD WT PECs, which displayed a coordinated expression with several type I interferon-stimulated genes (ISGs) and with key molecules involved in the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling pathway, two hallmarks in the lupus pathology. …”
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Genome-wide identification and expression analysis of ZF-HD family in sunflower (Helianthus annuus L.) under drought and salt stresses
Published 2025-02-01“…Conclusions Overall, this study enhances our comprehension of the function of ZF-HD genes in positive regulation of responsiveness to abiotic stress and provide key candidate genes for sunflower stress resistance breeding.…”
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Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data
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A review of the intertidal Medon Stephens (Coleoptera, Staphylinidae, Paederinae) with description of a new species on the East Asian coasts
Published 2025-02-01“…Detailed comparison of morphological characters and molecular analyses based on genetic divergence and gene tree monophyly for species delimitation support the validity of the new species. …”
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