Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

“…Two machine learning algorithms were used to further screen key genes. Genes with an area under curve (AUC) of > 0.7 in receiver operating characteristic (ROC) curves, significant expression and consistent trends across datasets were considered key genes. …”
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Statistical and machine learning based platform-independent key genes identification for hepatocellular carcinoma. by Md Al Mehedi Hasan, Md Maniruzzaman, Jie Huang, Jungpil Shin

“…To solve these problems, we have taken datasets from multiple platforms and designed a statistical and machine learning-based system to determine platform-independent key genes (KGs) for HCC patients. DEGs were determined from each dataset using limma. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

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Gene Therapy: A step toward advanced orthodontics – A narrative review by Monika Shukla, Shalu Jain, C. Munish Reddy, Pradeep Raghav, Kumar Amit, Rinchin Yangzom, Shivika Garg, Aastha Kamrani

Subjects: “…key words: bone repair…”
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Multivariate Cox regression analysis of prognostic genes and therapeutic mechanisms of gastric cancer by Yangyang Xiao, Zhiru Zhong, Chunli Yang, Zhiying Lin

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Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress by Xiao Wu, Yaoran Fan, Jianbin Feng, Keyi Ma, Jiale Li

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Evaluation of reference genes for gene expression analysis in Japanese flounder (Paralichthys olivaceus) under temperature stress by Ping Han, Jianming Chen, Zhennan Sun, Shengjie Ren, Xubo Wang

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Global biogeography and projection of antimicrobial toxin genes by Ya Liu, Yu Geng, Yiru Jiang, Jingyu Sun, Peng Li, Yue-zhong Li, Zheng Zhang

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Polymorphism of genes and drug-induced liver injury by P. Ye. Tkachenko, M. V. Mayevskaya, V. T. Ivashkin

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Engineering tomato disease resistance by manipulating susceptibility genes by Duoduo Wang, Palash Mandal, Md Sazan Rahman, Lirong Yang

“…This review highlights key advances in using gene editing tools to dissect and engineer tomato S genes for improved immunity. …”
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Genes for editing to improve economic traits in aquaculture fish species by Zituo Yang, Guihong Fu, May Lee, Shadame Yeo, Gen Hua Yue

“…By modifying key genes in fish, it is expected to rapidly enhance growth rate, disease resistance, and other economically important traits, leading to increased profitability, sustainability, and competitiveness of the industry. …”
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Identification and expression analysis of the ZF-HD gene family in castor by XU Xingyuan, HUANG Fenglan, ZHANG Chunlan, ZHU Mengyang, CUI Zhiyu, LIU Peng

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Key oncogenes and candidate drugs for hepatitis-B-driven hepatocellular carcinoma progression by Liqin Ruan, Ningbo Fang, Xinhua Zhao, Weili Chen, Zhaoping Wu, Xiaoyong Wu

“…Abstract Background This study aimed to uncover the key hepatitis-B (HB)-related liver cancer (LC) promoting genes, and clarity their interrelationships, enrichments, impacts on LC immune infiltration, and potential drugs targeting these genes. …”
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Chrysene alters the expression pattern of HSP70 genes in mandarin fish by Yufei Liu, Tiantian Chen, Jinliang Zhao, Xiaowu Chen

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Interactions between ABC gene polymorphisms and processing speed in predicting depression severity by Meijiang Jin, Lei Ji, Maojia Ran, Yan Bi, Hang Zhang, Yuanmei Tao, Hanmei Xu, Shoukang Zou, Hong Zhang, Tao Yu, Li Yin

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Ultrasound Radiogenomics-based Prediction Models for Gene Mutation Status in Breast Cancer by Zhai Yue, Tan Dianhuan, Lin Xiaona, Lv Heng, Chen Yan, Li Yongbin, Luo Haiyu, Dan Qing, Zhao Chenyang, Xiang Hongjin, Zheng Tingting, Sun Desheng

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Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study. by Nian Liu, Qian Deng, Zining Peng, Danning Mao, Yuanbo Huang, Fanyu Meng, Xiaoyu Zhang, Jiayan Shen, Zhaofu Li, Weitian Yan, Jiangyun Peng

“…The identification of EFEMP2, GABARAPL1, and TSPO as key target genes highlights potential common factors in both diseases. …”
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From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases by Qing Zhao, Linxin Wei, Youxin Chen

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Extensive paralogism in the environmental pangenome: a key factor in the ecological success of natural SAR11 populations by Carmen Molina-Pardines, Jose M. Haro-Moreno, Francisco Rodriguez-Valera, Mario López-Pérez

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Target miRNA identification for the LPL gene in large yellow croaker (Larimichthys crocea) by Kalim Ullah, Aslam Hossain, Mingyue Cao, Liangyi Xue, Yajun Wang

“…The investigation culminated in the identification of miR-84a and miR-1231-5p as key miRNAs that modulate fat hydrolysis, highlighting their potential roles in lipid metabolism. …”
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