Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce. by Sean T Tarr, Roberto G Lopez

“…Elevating CO2 concentrations from 500 to 800 μmol·mol-1 increased 'Rouxaï RZ' and 'Rex' fresh mass by 33 and 16%, respectively, while fresh mass did not increase from 800 to 1200 μmol·mol-1. Both cultivars had the greatest dry mass at 800 μmol·mol-1 CO2 across temperatures. …”
Get full text

Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews by Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan, Isabella Zhao

“…Objectives To identify the barriers and enablers to implementing clinical practice guidelines (CPGs) recommendations in primary care and to provide recommendations that could facilitate the uptake of CPGs recommendations.Design An overview of systematic reviews.Data sources Nine electronic databases (PubMed, Cochrane Library, CINAHL, MEDLINE, PsycINFO, Web of Science, Journals @Ovid Full Text, EMBase, JBI) and three online data sources for guidelines (Turning Research Into Practice, the National Guideline Clearinghouse and the National Institute for Health and Care Excellence) were searched until May 2021.Eligibility criteria Systematic reviews, meta-analyses or other types of systematic synthesis of quantitative, qualitative or mixed-methods studies on the topic of barriers and/or enablers for CPGs implementation in primary care were included.Data extraction and synthesis Two authors independently screened the studies and extracted the data using a predesigned data extraction form. …”
Get full text

Direct effects of prolonged TNF-α and IL-6 exposure on neural activity in human iPSC-derived neuron-astrocyte co-cultures by Noah Goshi, Doris Lam, Chandrakumar Bogguri, Vivek Kurien George, Aimy Sebastian, Jose Cadena, Nicole F. Leon, Nicholas R. Hum, Dina R. Weilhammer, Nicholas O. Fischer, Heather A. Enright

“…We found that exposure to TNF-α produced both a concentration-independent and concentration-dependent response in neural activity. …”
Get full text

A Personalized Muscle–Tendon Assessment and Exercise Prescription Concept Reduces Muscle–Tendon Imbalances in Female Adolescent Athletes by Theresa Domroes, Kolja Weidlich, Sebastian Bohm, Falk Mersmann, Adamantios Arampatzis

“…In the intervention group, athletes with a deficit in tendon stiffness (strain ≥ 9%; n = 6) or no muscle–tendon imbalances (strain between 4.5% and 9%; n = 15) performed exercises (3x/week for 32 weeks) with a personalized load to reach ~ 6.2% tendon strain to predominantly promote tendon or both muscle and tendon adaptation. Individuals with a muscle strength deficit (strain ≤ 4.5%; n = 1) trained with submaximal loads to failure to promote muscle strength. …”
Get full text

Oncometabolite D-2HG drives tumor metastasis and protumoral macrophage polarization by targeting FTO/m6A/ANGPTL4/integrin axis in triple-negative breast cancer by Siyue Zhang, Ning Zhang, Tong Wan, Yinqiao He, Jie Hao, Yiwei Liu, Yidong Liu, Bing Chen, Wenjing Zhao, Lijuan Wang, Dan Luo, Chao Gao, Qifeng Yang

“…Mechanistically, D-2HG enhanced global m6A RNA modifications in TNBC cells, notably upregulating m6A modification on ANGPTL4 mRNA, which was mediated by the inhibition of Fat-mass and obesity-associated protein (FTO), resulting in increased recognition of m6A-modified ANGPTL4 by YTH N6-methyladenosine RNA binding protein F1 (YTHDF1), thereby promoting the enhanced translation of ANGPTL4. …”
Get full text

Natural and Migration Balance of the Population in Sibiu County Between 1992 and 2021 by Raularian RUSU, Ciprian MOLDOVAN, Titus MAN, Elena-Manuela BÎRSĂNUC, Cosmina-Daniela URSU

Subjects: Get full text

Pain in pancreatitis: issue and ways out by A. V. Okhlobystin

“…It can be related to intraductal hypertension caused both by pancreatic juice outflow obstruction, and by increased volume as a result of activated stimulation. …”
Get full text

Assessment of Knowledge Gaps in Cervical Cancer Screening and HPV Vaccination Among Chinese Women: A Comprehensive Population-Based Study by Huang X, Ruan G, Sun P

“…Xinxin Huang,1 Guanyu Ruan,2 Pengming Sun2 1The Ministry of Health, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, People’s Republic of China; 2Laboratory of Gynecologic Oncology, Fujian Clinical Research Center for Gynecologic Oncology, Fujian Matermity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian Province, People’s Republic of ChinaCorrespondence: Guanyu Ruan; Pengming Sun, Email ruangy_fjsfy@163.com; sunfemy@hotmail.comBackground: While studies on cervical cancer screening (CCS) and human papillomavirus (HPV) vaccine uptake exist in China, few have examined both within populations participating in CCS programs.Methods: This cross-sectional, population-based survey included 37,797 women aged 18– 64 years attending gynecological outpatient clinics. …”
Get full text

Review: A systematic review of dairy cow health, welfare, and behaviour in year-round loose range housing by W.J. Harvey, L. Petrokofsky, M.W. Jordon, G. Arnott, L.W. von Walter, A. Malik, T. Carter, L.S. Wade, G. Petrokofsky

“…Data are also often presented in an aggregated form that limits meaningful comparisons. …”
Get full text

Penerapan Metode Extreme Programming pada Rancang Bangun Sistem Analisis Sentimen Portal Berita by I Gede Bagus Premana Putra, Made Sudarma, Ida Bagus Gede Manuaba

“…The sentiment analysis system can be developed using various techniques and services, one of which’s by integrating the Google NLP system and service, which already has a service to determine the sentiment score of each given sentence, as well as the application of a web scrapping techniques as a method for data collection. …”
Get full text

Modelling the air quality impacts of a zero emission zone scenario in the city of Milan by Andrea Piccoli, Valentina Agresti, Marco Bedogni, Giovanni Lonati, Guido Pirovano

“…Then we evaluated the benefits in terms of both air quality and citizens’ health. The assessment of the environmental and health effects is done thanks to a modelling suite composed of a road traffic, an emission, a hybrid air quality models, plus a fourth module for human health impacts. …”
Get full text

Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study by Yu. A. Kucheryavy, D. N. Andreyev, E. Yu. Eryomina, A. A. Gilmanov, O. V. Nazarova, Ye. A. Sidneva, Yu. G. Topalova

“…This prospective observational multicenter study demonstrated that the addition of Alfasoxx to standard GERD therapy contributes to a significant regression of both esophageal and extraesophageal symptoms, as well as a decrease in the need for antacid medications.…”
Get full text

Perancangan dan Pembuatan Sistem Informasi Retensi Rekam Medis Rawat Jalan di Puskesmas Jenggawah Kabupaten Jember by Andri Permana Wicaksono, Muhaiminul Aziz, Feby Erawantini, Ida Nurmawati

“…Jenis penelitian yang digunakan adalah pengembangan sistem dengan metode RAD (Rapid Application Development) dan menggunakan teknik pengumpulan data kualitatif berupa wawancara, observasi, dokumentasi, dan brainstorming. …”
Get full text

Types of electronic nicotine delivery systems (ENDS) used by people of different age and smoking status groups: results from a US nationally representative survey by Lucy Popova, Robert T Fairman, David L Ashley, Zachary B Massey, Bai Cham, Ruiyan Luo, Mohammed Alqahtani, Scott Weaver

“…Cigarette smoking status was also measured.Results We used weighted regression models to determine the association between ENDS device type current regular use and age group and the association between each ENDS type current regular use and smoking status separately for each age group. …”
Get full text

Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction by Jingrun Lin, Xiaoqiu Zhu, Xuan Li, Yu Hong, Yaohui Liang, Siqi Chen, Chenzhuo Feng, Lin Cao

“…Additionally, drugs were predicted as potential therapeutic candidates for POCD treatment. Conclusion Both aging and surgery have complex effects on the hippocampal transcriptome in mice. …”
Get full text

INTRA-REGIONAL DIFFERENTIATION OF ENTREPRENEURSHIP OF MUNICIPALITIES OF THE ŚWIĘTOKRZYSKIE VOIVODESHIP IN TERMS OF SUSTAINABLE DEVELOPMENT IN 2010 AND 2020 by Paweł Dziekański, Łukasz Popławski, Fabio Fragomeni

“…The variables were selected based on the availability of data from Statistics Poland for the years 2010 and 2020. …”
Get full text

Environmental and health risk assessment of polycyclic aromatic hydrocarbons and toxic elements in the red sea using Monte Carlo simulation by F. Alshaima Sayed, Mohamed Hamdy Eid, Ahmed M. El-Sherbeeny, Gouda Ismail Abdel-Gawad, Essam A. Mohamed, Mostafa R. Abukhadra

Subjects: Get full text

Riesgo de contagio por COVID-19 en un entorno urbano (Málaga, noviembre del 2020) by Ángel Miramontes Carballada, Rubén Lois González, María Jesús Perles Roselló, Jesús Miranda Páez

“…The search for correlation between the distribution of contagion and various factors of the natural environment and the human environment have been treated both at the urban micro-scale and on a planetary scale. …”
Get full text

Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

Subjects: Get full text

Outcomes of total hip replacement in adults with septic arthritis of the native hip joint: A systematic review by Teddy Cheong, Surya Varma Selvakumar, Ryan Kwang Jin Goh, Ing How Moo

“…Improvement in LLD ranged from 2.28 to 3.52 cm, with all studies reporting < 1 cm of LLD postoperatively. Conclusion THR, both single and two-staged, is an effective treatment option for septic arthritis of the native hip joint that and yields good functional outcomes and acceptable reinfection rates. …”
Get full text