Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe by Torsten B Neilands, Lynae A Darbes, James Mkandawire, Derek S Brown, Fred M Ssewamala, Judith A Hahn, Amy A Conroy, Nancy Mulauzi, Scott Tebbetts

“…Couples in the Mlambe arm will receive incentivised matched savings accounts and monthly sessions on financial literacy, relationship skills, and alcohol reduction education and counselling. …”
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Variability of daily feed intake as an indicator of resilience in Pietrain pigs by C. Casto-Rebollo, P. Nuñez, S. Gol, J. Reixach, N. Ibáñez-Escriche

“…Progeny mortality was calculated for each contemporary group (farm and batch) of the offspring, and sires were classified into three levels of resilience. …”
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Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing by Roland Diel, Niklas Lampenius

“…**Methods:** A deterministic decision-analytic model was developed simulating the number of major bleedings, ischemic strokes, and hemorrhagic strokes and their associated costs by utilizing PST compared to those of treatment with NOAC. Data on the rates of these adverse events in both groups during the 1st year of treatment was taken from the NOAC approval studies. …”
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Riesgo de contagio por COVID-19 en un entorno urbano (Málaga, noviembre del 2020) by Ángel Miramontes Carballada, Rubén Lois González, María Jesús Perles Roselló, Jesús Miranda Páez

“…The search for correlation between the distribution of contagion and various factors of the natural environment and the human environment have been treated both at the urban micro-scale and on a planetary scale. …”
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The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker by Hao-ming He, Ying-ying Xie, Qiang Chen, Yi-ke Li, Xue-xi Li, Sun-jing Fu, Na Li, Yan-ru Han, Yan-xiang Gao, Jin-gang Zheng

“…Results A total of 673 (3.9%) cardiovascular deaths occurred during a median follow-up of 8.92 years. …”
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A Study Exploring Relationship between Risk Factors and Resilience among Youth by Fenny Leferty Kharpuri, Ramya Bhaskar

“…Attention to risk factors at both individual and social levels is required to provide the fullest understanding of healthy youth and improve their well-being with enhanced resilience.…”
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The association between tobacco and alcohol use and health outcomes in individuals living with diabetes and prediabetes in South Africa: A cross-sectional study by S J Mulder, T Chivese, C O Egbe

“…Smoking and alcohol misuse are lifestyle factors that can be controlled and have significant health effects. Both these factors increase the risk of developing conditions such as diabetes mellitus because they affect glucose metabolism and can interfere with blood glucose control in individuals with diabetes. …”
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Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing by Johanna Graue, Melanie Timmen, Katharina Schmitz, Daniel Kronenberg, Markus Böhm, Kishor K. Sivaraj, M. Gabriele Bixel, Richard Stange

“…All four melanocortin receptor-molecules were expressed in murine osteoblastic cells but in very limited amounts and this did not change upon treatment with inflammatory cytokines or α-MSH or both at the same time. Callus formation in fractured femurs of α-MSH-treated mice was slightly delayed at day 14 post fracture with regard to less cartilage formation (NaCl: 19.9%; α-MSH: 13.5%) and soft tissue remodeling (NaCl: 15.2%; α-MSH: 19.5%) but these results were not significantly different and fracture healing overall occurred in a regular way. …”
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Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic behavioral variant frontotemporal degeneration by Ting Shen, Jacob W. Vogel, Vivianna M. Van Deerlin, EunRan Suh, Laynie Dratch, Jeffrey S. Phillips, Lauren Massimo, Edward B. Lee, David J. Irwin, Corey T. McMillan

“…Functional enrichment analyses were conducted on each gene list significantly associated with cortical thickness. …”
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Development and validation of a novel bleeding risk prediction tool for aspirin users with a low body mass index by Lu Yifang, Lei Wanlin, Wang Maofeng

“…A total of 2436 aspirin users with a low BMI were included in this study conducted at the Affiliated Dongyang Hospital of Wenzhou Medical University. Patient data, comprising demographics, clinical characteristics, comorbidities, medical history, and laboratory tests, were collected. …”
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Vinblastine resets tumor-associated macrophages toward M1 phenotype and promotes antitumor immune response by Jing Wang, Jin Wang, Yi-Na Wang, Yuan-Yuan Wang, Wen-Juan Bai, Nai-Jun Miao

“…As a microtubule-targetting drug, vinblastine (VBL) has been used in chemotherapy. However, no study to date has explored the effect of VBL on TAM shape changes and its role in tumor immune response.Method We used fluorescent staining of the cytoskeleton and quantitative analysis to reveal the morphological differences between M0, M1, M2, TAM and VBL-treated TAM. …”
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Impact of Oxycodone HCl Extended-release Formulary Restrictions on Extended-release Opioid Market Share, Healthcare Resource Utilization and Costs in Commercial and Medicare Plans by Rolin L. Wade, Chi-Chang Chen, Ajita P. De, Jaren C. Howard

“…Patients from each restricted plan (cases) were matched to patients in an unrestricted plan (controls) on key patient characteristics. …”
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The Validity of a Portable Strain-Gauge Apparatus Versus a Commercial Isokinetic Dynamometer for Evaluating Knee Extension Kinetics by Dustin Oranchuk, Chris Juneau, Shelley Diewald, Jono Neville, John Cronin

“… # Methods Healthy participants (8 males and 6 females; age 30.2±7.1 years) volunteered and performed knee extensions at a 90° knee angle on a dynamometer and a treatment plinth with a portable strain-gauge. Peak force (PF), peak rate of force development (PRFD), rate of force development (RFD~2080~) and impulse (IMP~2080~) from 20-80% of onset to peak force were assessed using both strain-gauge and isokinetic dynamometer. …”
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A COMPARATIVE STUDY ON THE EFFECT OF SISAL FIBRE AND WASTE PLASTIC STRIPS IN STRUCTURAL STRENGTH IMPROVEMENT OF TROPICAL BLACK CLAY by YOHANNA PAUL, BADAMASI ABDULRAHMAN, ISHOLA KAZEEM, ODOH KELVIN CHUKWUEBUKA, ABDULKADIR MOHAMMED NYAKO, FWANGSHAK GAYUS MIJE

“…In the case soil treated with waste plastic strips, liquid values increased from 43.4% for the natural soil to a highest value of 58% at 1% waste plastic strips and thereafter decreased to 49.15% at 2% waste plastic strips content. Plastic limit for both BCS-sisal fibre/ waste plastic strips initially decreased from its natural value of 25.78 to 15.55 and 14.77% when treated with sisal fibre and waste plastic strips respectively at 0.5% admixtures content. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…The XBB variant exhibited a significantly lower rate of severe cases, with most infections being mild (P < 0.05). …”
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Community-based HPV self-collection versus visual inspection with acetic acid in Uganda: a cost-effectiveness analysis of the ASPIRE trial by Joel Singer, Angeli Rawat, Heather Armstrong, Josaphat Byamugisha, Gina S Ogilvie, Alex K Mezei, Heather N Pedersen, Stephen Sy, Catherine Regan, Sheona M Mitchell-Foster, Musa Sekikubo, Jane J Kim, Nicole G Campos

“…The trial compared screening uptake and compliance with follow-up in two arms: (1) community-based (ie, home or workplace) self-collected HPV testing (facilitated by community health workers) with clinic-based visual inspection with acetic acid (VIA) triage of HPV-positive women (‘HPV-VIA’) and (2) clinic-based VIA (‘VIA’). In both arms, VIA was performed at the local health unit by midwives with VIA-positive women receiving immediate treatment with cryotherapy.Design We informed a Monte Carlo simulation model of HPV infection and cervical cancer with screening uptake, compliance and retrospective cost data from the ASPIRE trial; additional cost, test performance and treatment effectiveness data were drawn from observational studies. …”
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Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

“…It became increasingly recognized that the immune response was a key mediator of illness severity and that its mechanisms needed to be better understood. Early infection of both tissue and immune cells, such as macrophages, leading to pyroptosis-mediated inflammasome production in an organ system critical for systemic oxygenation likely plays a central role in the morbidity wrought by SARS-CoV-2. …”
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The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant by S. A. Frolov, A. M. Kuzminov, V. Yu. Korolik, I. S. Bogormistrov, M. O. Chernozhukova, Sh. T. Minbayev

“…Strict patient selection with transsphincteric rectal fistulas and careful preoperative investigation allow to improve treatment results due to technical simplicity of the method as well as due to low complication rate both in early, and in remote periods.…”
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Causal machine learning models for predicting low birth weight in midwife-led continuity care intervention in North Shoa Zone, Ethiopia by Wudneh Ketema Moges, Awoke Seyoum Tegegne, Aweke A. Mitku, Esubalew Tesfahun, Solomon Hailemeskel

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Acceptability and feasibility of pre-exposure prophylaxis for bacterial STIs: a systematic review. by Julie-Anne Carroll, Amy B Mullens, Sarah Warzywoda, Philip R A Baker, Meika Stafford, Faye McMillan, Jacintha Manton, Daniel Demant

“…This process supports the improvement of health outcomes, strengthens healthcare systems, and ensures that healthcare interventions, such as STI PrEP, are effectively understood and implemented by both healthcare providers and at-risk populations. …”
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