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G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide.
Published 2018-12-01“…G-quadruplexes are non-canonical nucleic-acid structures that control transcription, replication, and recombination in organisms. …”
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THE FREQUENCY AND FITNESS OF m6A-ASSOCIATED VARIANTS COULD BE MODULATED BY THE THERMODYNAMIC STABILITY OF AN OVERLAPPING G-QUADRUPLEX
Published 2023-10-01“…Objective: Post-transcriptional modifications like m6A (N6-methyladenosine) and secondary structures like G-quadruplex (G4) are formations that play a vital role in RNA processing. …”
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Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation.
Published 2021-01-01“…Maintaining genome integrity is particularly important in germ cells to ensure faithful transmission of genetic information across generations. Here we systematically describe germ cell mutagenesis in wild-type and 61 DNA repair mutants cultivated over multiple generations. ~44% of the DNA repair mutants analysed showed a >2-fold increased mutagenesis with a broad spectrum of mutational outcomes. …”
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A Dataset Curated for the Assessment of G4s in the LncRNAs Dysregulated in Various Human Cancers
Published 2025-05-01“…Abstract Dysregulated expression of long non-coding RNAs (lncRNAs) in cancer contributes to various hallmarks of the disease, presenting novel opportunities for diagnosis and therapy. G-quadruplexes (G4s) within lncRNAs have gained attention recently; however, their systematic evaluation in cancer biology is yet to be performed. …”
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