Investigation of Black Carbon Wet Deposition to the United States from National Atmospheric Deposition Network Samples by Piyaporn Sricharoenvech, Ross Edwards, Müge Yaşar, David Gay, James J. Schauer

“…Wet deposition BC concentrations varied from less than 0.3 µg L−1 to 38.7 µg L−1 with a median of 3.50 µg L−1. Associated BC wet deposition fluxes ranged from near zero to 9.1 g ha−1 wk−1, with a median of 0.87 g ha−1 wk−1. …”
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FAN score predicts prognosis after platinum-based first-line chemotherapy in patients with metastatic urothelial carcinoma by Yu Ishizuya, Atsunari Kawashima, Yuki Horibe, Akinaru Yamamoto, Masaru Tani, Akihiro Yoshimura, Liu Yutong, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Toshihiro Uemura, Gaku Yamamichi, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Norio Nonomura

“…We included 126 patients with mUC who received platinum-based first-line chemotherapy. The median PFS and overall survival (OS) were 6.3 months (95% confidence interval [CI] 4.5–8.0) and 14.0 months (95% CI 11.1–16.9), respectively. …”
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Investigation of Serum Cartonectin Concentrations in Pregnant Women with Gestational Diabetes Mellitus; a Prospective Non-Interventional Cohort Study by Onur Gebes, İbrahim Kale, Tuba Beser Gebes, Murat Muhcu

“…The study and control groups were similar in terms of median serum cartonectin concentrations (6.28 ng/ml and 7.13 ng/ml, respectively, p=0.165). …”
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Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial by Gang Chen, Dong-Chen Sun, Yi Ba, Ya-Xiong Zhang, Ting Zhou, Yuan-Yuan Zhao, Hong-Yun Zhao, Wen-Feng Fang, Yan Huang, Zhen Wang, Chao Deng, De-Sheng Hu, Wei Wang, Jin-Guan Lin, Gui-Ling Li, Su-Xia Luo, Zhi-Chao Fu, Hai-Sheng Zhu, Hui-Li Wang, Sheng-Li Cai, Xiao-Qiang Kang, Li Zhang, Yun-Peng Yang

“…In immunotherapy-naive NPC patients (n = 12), ORR was 33.3%, disease control rate (DCR) was 75%, and median progression-free survival (PFS) was 10.8 months (95% CI, 1.3 to not estimated). …”
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Patterns of Comorbidity and Multimorbidity Among Patients With Multiple Sclerosis in a Large US Commercially Insured and Medicare Advantage Population by Dingwei Dai, Ajay Sharma, Amy L. Phillips, Carroline Lobo

“…Multiple comorbidities were highly prevalent (median, 4 comorbidities), particularly among Medicare Advantage patients younger than 65 (median, 6) and Medicare Advantage patients 65 and older (median, 7). …”
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Incidence, prevalence, and predictors of osteoporotic fracture in adult lung transplant recipients by Elisabeth Ng, Shanal Kumar, Eldho Paul, Daniel Bennett, Luisa Rosi, Louise Fuller, Lauren Chiu, Shoshana Sztal-Mazer, Steven Ivulich, Greg Snell, Leon A. Bach, Kathryn L. Hackman

“…Results: Four hundred and five LT recipients (41% female, median age 59 years) had a median follow-up of 4.9 years (interquartile range 3.4-6.7). …”
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Design of an Inhalation Chamber and Metrology Assessment to Study Tungsten Aerosol Neurotoxic Effects by Léo Macé, Chrystelle Ibanez, Thomas Gelain, Cécile Bodiot, Laure Juhel, François Gensdarmes

“…Additionally, the count median diameter determined from the electrical mobility measured by the EEPS equaled 0.17 µm, which falls beyond both the intended range of the instrument and the range of previously studied aerodynamic sizes. …”
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Malnutrition risk, weight loss, and subsequent survival in patients listed for heart transplantation by Tae Kyung Yoo, MD, MS, Satoshi Miyashita, MD, Ariella Stein, MSCIS-HI, Michael Wu, BS, MPH, Lauren Parsly Read-Button, MPH, RD, LDN, Masashi Kawabori, MD, Greg S. Couper, MD, Edward Saltzman, MD, Amanda R. Vest, MBBS, MPH

“…Results: The 1,024 patients [76% male; median age 55 (46–61) years; HT operation n = 656] had median follow-up of 4.6 (interquartile range 1.6–8.7) years. …”
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Vascular access on YouTube: Navigating the stream of information for hemodialysis patients by Alp Yildirim, Muhammed Sefa Saglam, Serkan Mola, Ali Baran Budak

“…The videos amassed 12,854,643 views, with a median duration of 5 minutes and a median of 3412 views per video. …”
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Decompressive craniectomy in subarachnoid hemorrhage compared to other etiologies: An institutional experience of 11 years by Emilia K. Pesonen, Aleksi Lammi, Cheng Qian, Mikael Von und Zu Fraunberg, Tommi K. Korhonen, Sami Tetri

“…Results: One hundred twenty-four DCs were conducted to patients aged a median of 40 years (SD 16), of whom 88 (71%) were male. …”
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The sarcoma ring trial: a case-based analysis of inter-center agreement across 21 German-speaking sarcoma centers by Siyer Roohani, Jolina Handtke, Kamal Hummedah, Markus Albertsmeier, Dimosthenis Andreou, Leonidas Apostolidis, Marinela Augustin, Sebastian Bauer, Moritz Billner, Florian Bösch, Christoph K. W. Deinzer, Niklas Deventer, Anna Duprée, Franziska Eckert, Lars Engel, Katja Fechner, Hagen Fritzsche, Verena Gaidzik, Saeed Ghani, Robert Grützmann, Wiebke K. Guder, Rainer Hamacher, Judith S. Hecker, Anne Hendricks, Axel Hillmann, Philipp Houben, Georg Hübner, Philipp Ivanyi, Christina Jentsch, Maren Jordan, Peter Kappl, Moritz Kaths, Torsten Kessler, Johanna Kirchberg, Carolin Knebel, Robert Krempien, Burkhard Lehner, Ulrich Lenze, Lars H. Lindner, Alisa Martina Lörsch, Nadia Maguire, Sophie Müller, Pompiliu Piso, Vlatko Potkrajcic, Peter Reichardt, Stephan Richter, Simone Schewe, Lars M. Schiffmann, Felicitas Scholten, Jana Käthe Striefler, Matthias Schwarzbach, Katharina Seidensaal, Sabine Semrau, Joanna Szkandera, Christoph J. Szuszies, Beate Timmermann, Armin Tuscherer, Armin Wiegering, Moritz T. Winkelmann, David Kaul, Jens Jakob

“…Agreement percentages for case 1 to 5 were 14.3%, 61.9%, 33.3%, 52.4% and 9.3%, with a median agreement percentage of 33.3%. Grouping pre- and postoperative therapies as "perioperative" and including recommendations with and without regional hyperthermia raised the median agreement to 47.6%. …”
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Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme by Stephen J Walters, Daniel Hind, Richard M Jacques, Steven A Julious, Joanne Rothwell, Oscar Bortolami, Laura Flight, Inês Bonacho dos Anjos Henriques-Cadby, Christopher Knox, Ben Nadin, Michael Surtees

“…The final recruitment target sample size was achieved in 56% (85/151) of the RCTs and more than 80% of the final target sample size was achieved for 79% of the RCTs (119/151). The median recruitment rate (participants per centre per month) was found to be 0.92 (IQR 0.43–2.79) and the median retention rate (proportion of participants with valid primary outcome data at follow-up) was estimated at 89% (IQR 79–97%).Conclusions There is considerable variation in the consent, recruitment and retention rates in publicly funded RCTs. …”
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The role of simultaneous stereotactic biopsy and radiofrequency ablation in the management of brain neoplasms in countries with limited financial resources by Mohamed Ashraf Mahmoud, Abdelrahman El Gayar, Shafik T El Molla, Hesham Radwan, Tarek H El Serry, Ashraf Al Abyad

“…From the ablated tumors, 17 were primary, 4 were metastatic, and 1 was in-field necrosis. Median tumor volume was 6 cm3 and mean was 10.2 cm3 (range, 0.5–40 cm3). …”
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Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types by Jeanne Shen, Sergio Pereira, Chan-Young Ock, Yung-Jue Bang, Seulki Kim, Sehhoon Park, Se-Hoon Lee, George A Fisher, Young Kwang Chae, Yoon-La Choi, Jin-Haeng Chung, Tony S K Mok, Leeseul Kim, Jun-Eul Hwang, Gahee Park, Sanghoon Song, Seunghwan Shin, Yoojoo Lim, Wonkyung Jung, Heon Song, Hyojin Kim, Taebum Lee, Sukjun Kim, Chang Ho Ahn, Seokhwi Kim, Ben W Dulken, Stephanie Bogdan, Maggie Huang, Chiyoon Oum, Siraj M. Ali

“…We evaluated the correlation between the IIP and ICI treatment outcomes in terms of objective response rates (ORR), progression-free survival (PFS), and overall survival (OS) in a cohort of 1,806 ICI-treated patients representing over 27 solid tumor types retrospectively collected from multiple institutions.Results We observed an overall IIP prevalence of 35.2% and significantly more favorable ORRs (26.3% vs 15.8%), PFS (median 5.3 vs 3.1 months, HR 0.68, 95% CI 0.61 to 0.76), and OS (median 25.3 vs 13.6 months, HR 0.66, 95% CI 0.57 to 0.75) after ICI therapy in IIP compared with non-IIP patients, respectively (p<0.001 for all comparisons). …”
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tDCS cranial nerve Co-stimulation: Unveiling brainstem pathways involved in trigeminal nerve direct current stimulation in rats by Alireza Majdi, Liyi Chen, Lars E. Larsen, Robrecht Raedt, Myles Mc Laughlin

“…Keywords: tDCS; trigeminal nerve; locus coeruleus; Dorsal raphe nucleus; median raphe nucleus.…”
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Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study by Michael J. Reinhardt, Björn Ohmstede, Luz Angela Torres-de la Roche, Rudy Leon De Wilde

“…A reduction of applied activity from a median of 18 MBq in group 1 to a median of 12 MBq in group 2 had no negative effect on the SLN identification. …”
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Acute Toxicity of Xylene on the African Catfish <i>Clarias gariepinus</i> by I.C. Davies, E.S. Erondu, A.I. Hart, L.C. Osuji

“…The median lethal time LT50 recorded was 55.7 hours. There was a strong correlation between (%) mortality in Probits and the Log10 Dose (R²=0.9772). …”
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Peripheral neuropathy in the phase 3 ASPEN study of Bruton tyrosine kinase inhibitors for Waldenström macroglobulinemia by Benjamin M. Heyman, Stephen S. Opat, Björn E. Wahlin, Meletios-Athanasios C. Dimopoulos, Jorge J. Castillo, Alessandra Tedeschi, Constantine S. Tam, Christian Buske, Roger G. Owen, Véronique Leblond, Judith Trotman, Gisoo Barnes, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Jeffrey V. Matous

“…Overall, 35 patients (71.4%) experienced resolution of PN symptoms, with a median time to resolution of 10.1 months (range, 1-46.8). …”
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Antihypertensive effect of sinapine extracted from rapeseed meal in 2K1C hypertensive rats by Gaoyuan Yang, Lin Zhu, Yu Wang, Yang Yu, Xiaoguang Liu, Jingbo Xia, Yunjie Yang, Huiguo Wang, Baomin Feng

“…Twokidney, oneclip (2K1C) hypertensive rats were given sinapine for four weeks, with weekly blood pressure monitoring. The renin angiotensin aldosterone system (RAAS), including the levels of renin, angiotensin I (Ang I), angiotensin II (Ang II), aldosterone (ALD), angiotensin-converting enzyme (ACE) and other molecules related to blood pressure, such as NO, prostacyclin (PGI2), endothelin-1 (ET1), and thromboxane A2 (TXA2), were measured in rat blood. …”
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ANALYTICAL JOURNEYS IN THREE PIECES FOR CLARINET SOLO BY CORNEL ŢĂRANU by Cristian BENCE-MUK

“…The second piece, Improvisazione, was written long time before the other two and represents a median contrast, where the sonorous discourse is delivered in a quasi-improvisational development. …”
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