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24981
Rsp5-mediated ubiquitination of a functional analog of the Rim8 arrestin facilitates Rim pathway activation in Cryptococcus neoformans
Published 2025-08-01“…Using an unbiased screen for proteins that are ubiquitinated by Rsp5 in acidic and alkaline pH, we identified a new component of the C. neoformans Rim pathway that is targeted by Rsp5 for ubiquitination and shares protein features with the ascomycete Rim8/PalF proteins. Rsp5-mediated ubiquitination facilitates protein interactions with Vps23, a downstream trafficking component of the Pal/Rim pathway. …”
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24982
LINC01322 may serve as a potential diagnostic marker for advanced stage tumors in renal cell carcinoma patients eligible for total nephrectomy
Published 2024-12-01“…For the first time in the present study, we assessed the LINC01322 RNA expression levels in RCC patients to introduce that as a potential tumor marker among these patients. …”
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24983
Annotation-free prediction of microbial dioxygen utilization
Published 2024-10-01“…However, nearly all microbes—aerobes, anaerobes, and facultative organisms alike—express enzymes whose substrates include O2, if only for detoxification. This presents a challenge when trying to assess which organisms are aerobic from genomic data alone. …”
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24984
Bevacizumab in Platinum-Sensitive Recurrent Epithelial Ovarian Cancer: A Risk-Stratified Analysis
Published 2025-06-01“…<b>Background and Objectives:</b> Epithelial ovarian cancer (EOC) is a complex disease characterized by heterogeneous clinical, pathological, and molecular features. Diagnosed frequently at advanced stages, it presents significant challenges in treatment due to the risks of resistance and recurrence. …”
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24985
DVAEGMM: Dual Variational Autoencoder With Gaussian Mixture Model for Anomaly Detection on Attributed Networks
Published 2022-01-01“…An adversarial mechanism makes the encoder make more accurate estimates of how potential features might be distributed. As a result, decoders can make graphs that are more like the original graph. …”
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24986
Bangladeshi Vehicle Classification and Detection Using Deep Convolutional Neural Networks With Transfer Learning
Published 2025-01-01“…In this paper, we have presented a vehicle classification and detection system to detect and classify low-speed and high-speed Bangladeshi vehicles. …”
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24987
Innovative engineering training in a competitive educational environment
Published 2021-05-01“…This raises the dilemma of creating a new competitive educational environment based on the use of competitiveness.The aim of the present research is to increase the efficiency of university students' training for innovative engineering activities due to high motivation to master it through the use of competitiveness.Methodology and research methods. …”
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24988
Association of ankylosing spondylitis activity indicators in a Russian population of patients with STAT4 rs7574865 gene polymorphism
Published 2019-05-01“…Age, gender, duration, and specific features of AS onset, ESR, and CRP levels were assessed. …”
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24989
Determination of key parameters for gathering and transmission process of Fuxing highly waxy shale oil at low temperatures
Published 2024-07-01“…Objective Condensate gas-containing light shale oil extracted by Sinopec in the Fuxing area features high solidification points and wax contents, indicating susceptibility to condensation and wax precipitation. …”
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24990
Comparison of Myometrial Invasion Depth Examination Methods in Endometrial Cancer
Published 2024-05-01“…Background: Endometrial cancer (EC) is often presents in the postmenopausal period. Among the risk elements are obesity, early menarche, late menopause, unopposed estrogen exposure associated with nulliparity, diabetes, advanced age (>55 years), and tamoxifen use. …”
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24991
COMPARATIVE CLINICAL CHARACTERISTICS OF PATIENTS WITH VARIOUS FORMS OF PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH CONGENITAL HEART DISEASE, ACCORDING TO THE CLINICAL CLASSIFIC...
Published 2019-12-01“…Analyzing the data of patients with PAH-CHD, we found various clinical, functional, physical and hemodynamic features of these patients. With comparable 6MWT and FC (WHO), patients with Eisenmenger syndrome have the highest values of PAP and PVR, as well as lower values of arterial blood oxygen saturation compared to other subgroups of PAH-CHD. …”
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24992
MDO of Robotic Landing Gear Systems: A Hybrid Belt-Driven Compliant Mechanism for VTOL Drones Application
Published 2025-06-01“…The proposed system design utilizes compliant mechanisms featuring a series of three-flexure hinges (3SFH), to reduce the number of articulated drivetrain components and actuators. …”
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24993
Development of E-Modules based on Contextual Teaching and Learning (CTL) on the actualization of Pancasila values
Published 2025-02-01“…Interactive features, such as quizzes, simulations, and context-based discussions, help increase students' active participation in learning. …”
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24994
Mitochondrial Myopathy Associated with Thymidine Kinase-2 Enzyme Deficiency in a Child of the First Year of Life: Case Report
Published 2025-05-01“…Early diagnosis of the disease is important because there is a pathogenetic treatment in the form of the use of specialized foods containing deoxynucleosides.Case report. The article presents the clinical features of the infantile form of TK2-associated mitochondrial myopathy in a 7.5-month-old girl. …”
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24995
HUMAn, a Real-Time Evolutive Patient Model for Major Incident Simulation: Development and Validation Study
Published 2025-03-01“…During the validation phase, the evolution of nine simulated patients presenting pathologies devised to test the different systems and their interactions was assessed. …”
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24996
Ammonia‐free natural rubber latex photo‐resin for sustainable 3D printing of highly stretchable and tough elastomers
Published 2025-04-01“…In this study, we developed an ammonia‐free natural rubber latex‐based photo‐resin featuring an ultra‐high molecular weight polymer with low viscosity (<10 Pa·s) and rapid curing speed (~11 s, corresponding to gelling point), making it highly suitable for VPP. …”
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24997
The Relationship between Skin Diseases and Nutritional Deficiencies in Children
Published 2025-02-01“…Aims: This review aims to explore the relationship between nutritional deficiencies and skin diseases in children, emphasizing clinical features, diagnostic approaches, and effective treatment strategies. …”
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24998
Encefalitis autoinmune asociada a anticuerpos anti-LGI1: revisión de sus aspectos clínicos, diagnósticos y terapéuticos
Published 2025-05-01“…This condition typically presents with a subacute course of focal seizures, behavioral disturbances, and memory impairment, often accompanied by faciobrachial dystonic seizures. …”
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24999
Quality Parameters of Plum Orchard Subjected to Conventional and Ecological Management Systems in Temperate Production Area
Published 2024-08-01“…The fruit morphometric features (color, firmness, soluble solid content, titratable acidity, and total sugar) were analyzed during their raw fruit state, while different fruit-sample extracts were assessed for phytochemical compounds and heavy metal concentrations, specifically, zinc, copper, nickel, and cadmium. …”
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25000
Development of the Big Ten Academic Alliance Collaborative for Women in Medicine and Biomedical Science: “We Built the Airplane While Flying It”
Published 2025-01-01“…In June 2024, The Ohio State University hosted the inaugural CommUNITYten conference in Columbus, Ohio, featuring 5 keynote presentations, 9 breakout sessions, and networking opportunities across one and a half days of curated programming. …”
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