The state of lipid metabolism in patients with acute coronary syndrome and chronic kidney disease depending on glomerular filtration rate and smoking factor by O. V. Yadzhyn, T. M. Solomenchuk

“…Aim. To study the features of lipid metabolism disorders in patients with acute coronary syndrome (ACS), depending on glomerular filtration rate (GFR) and smoking factor. …”
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Expression of CIP2A and CD44v6 in condyloma acuminatum-involved skin and its correlation with patients' prognosis by ZHANG Yijie, YANG Can, LIN Yongli

“…Real-time fluorescence quantitative PCR was used to detect the expression levels of CIP2A and CD44v6 mRNA in the tissue specimens. …”
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Trade-offs and synergies for urban Production-Living-Ecological spatial Patterns-Comparison study between Fuzhou, China, and Saskatoon, Canada by Xi Wang, Xiaomei Li, Jinming Sha, Hao Zhang, Eshetu Shifaw, Xulin Guo, Shuhui Lai, Jinliang Wang

“…First, the paper identified the PLE spaces by integrating multi-source data, then analyzed the PLE spatial agglomeration characteristics by using the average nearest neighbor and kernel density analysis, finally detected the trade-offs and synergies between functional spaces by Spearman correlation and bivariate spatial autocorrelation. …”
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IDIOPATHIC LOBULAR PANNICULITIS IN RHEUMATOLOGY PRACTICE: THE AUTHORS’ OWN DATA by O. N. Egorova, B. S. Belov, S. I. Glukhova, S. G. Radenska-Lopovok

“…The disease was found in all age groups, but it accounted for more than half (57%) of cases at the most able-bodied age (45–60 years). Analysis of the clinical manifestations of ILP could identify its four types: nodular (n=30), plaque (n=10), infiltrative (n= 5), and mesenteric (n=12), which were characterized by typical clinical features. …”
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Infant Type Ia Supernovae from the KMTNet. I. Multicolor Evolution and Populations by Yuan Qi Ni, Dae-Sik Moon, Maria R. Drout, Youngdae Lee, Patrick Sandoval, Jeehye Shin, Hong Soo Park, Sang Chul Kim, Kyuseok Oh

“…Seven are detected ≲1 day (as early as ≲1 hr) since the estimated epoch of first light and the rest ≲3 days. …”
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PERIODONTOLOGICAL STATUS OF PATIENTS WITH DENTOMAXIMAL ANOMALIES BEFORE ORTHODONTIC TREATMENT by V.S. Melnyk, K.V. Zombor, S.V. Melnyk

“…A special place among the factors contributing to the development of gum recession is occupied by anatomical and physiological features: the biotype of the gums, the volume and bone loss of the alveolar process of the jaw. …”
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Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae by Ai Guo, Dianbao Zuo, Li Shi, Ming Guo, Jinquan Li, Caili Li, Puqing Wang, Xiaodong Sun, Ming Sang

“…More importantly, we established the murine pneumonia infection models through nasal instillation, assessed the therapeutic potential of the phage in vivo by observing pathological morphology via HE staining, detecting pro-inflammatory cytokine levels via qPCR and ELISA, and monitoring bacterial load changes in lung tissue through PCR analysis. …”
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Characterization of full-length long noncoding RNAs and identification of virus-responsive lncRNAs in Sogatella furcifera by Yawen Ban, Yawen Ban, Ting Cui, Ting Cui, Lifei Zhao, Lifei Zhao, Xue Li, Xue Li, Qing Bai, Qing Bai, Qingfa Wu, Qingfa Wu

“…These lncRNAs displayed canonical features, including lower GC content, shorter transcript length, and fewer exons. …”
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Disruption of mgrB gene by ISkpn14 sourced from a bla KPC−2 carrying plasmid mediating polymyxin resistance against carbapenem-resistant Klebsiella pneumoniae during treatment: stu... by Ziyao Li, Zichen Lei, Xinmeng Liu, Feilong Zhang, Xinrui Yang, Yongli Wu, Chen Li, Jiankang Zhao, Yulin Zhang, Yanning Hua, Binghuai Lu, Bin Cao

“…Methods The within-host evolution relationship and molecular features of both CRKPs were determined by pulsed-field gel electrophoresis (PFGE) and whole-genome sequencing (WGS). pKP31311_KPC-2 plasmid genome structures contained in the above two CRKPs were aligned with the homologic plasmids, retrieved from the NCBI genome database via comparative genomic analysis. …”
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Improved CAR internalization and recycling through transmembrane domain optimization reduces CAR-T cytokine release and exhaustion by Shufeng Xie, Shufeng Xie, Jinlan Long, Ruiheng Wang, Ruiheng Wang, Rufang Xiang, Rufang Xiang, Huajian Xian, Yixin Wang, Weiyu Dou, Wenjie Zhang, Dan Li, Ting Kang, Zhihong Chen, Zhihong Chen, Chunjun Zhao, Zhenshu Xu, Han Liu

“…RNA sequencing is used to detect the transcriptome of activated CAR-T cells. …”
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Exploring the mechanism of Lingbao Huxin Dan in the treatment of bradycardia based on atrioventricular node electrical signal conduction by Jing Zhang, Guobin Zheng, Shangjing Liu, Yaodong Miao, Shu Yang, Sheng Li, Zhihui Yang, Danping Zhuo, Rui Guo, Yang Guo, Rongjiang Shao, Yunqing Hua, Chuanrui Ma

“…The hearts and serum samples were collected to detect heart rate and related gene expression which were screened through network pharmacology analysis, as well as to evaluate the effect of Lingbao Huxin Dan on ion channels in the cardiac conduction system. …”
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Testicular large B‐cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL by Alfredo Rivas‐Delgado, Cristina López, Guillem Clot, Ferran Nadeu, Marta Grau, Gerard Frigola, Jan Bosch‐Schips, Josefine Radke, Naveed Ishaque, Miguel Alcoceba, Gustavo Tapia, Luis Luizaga, Carmen Barcena, Nicholas Kelleher, Neus Villamor, Tycho Baumann, Ana Muntañola, Juan M. Sancho‐Cia, Alejandro M. García‐Sancho, Eva Gonzalez‐Barca, Estella Matutes, Jordi A. Brito, Kennosuke Karube, Itziar Salaverria, Anna Enjuanes, Stefan Wiemann, Frank L. Heppner, Reiner Siebert, Fina Climent, Elías Campo, Eva Giné, Armando López‐Guillermo, Silvia Beà

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Protocol for the development of a tool (INSPECT-SR) to identify problematic randomised controlled trials in systematic reviews of health interventions by Elizabeth Loder, Jill Alison Hayden, David Torgerson, Tianjing Li, Wentao Li, Rui Wang, Ben W Mol, Lisa Bero, Jamie J Kirkham, Lisa Parker, Mike Clarke, Jo C Dumville, Calvin Heal, Lyle Gurrin, Andreas Lundh, Madelon van Wely, Toby Lasserson, Alison Avenell, Neil E O'Connell, Andrew Grey, Jack Wilkinson, George A Antoniou, Kylie Elizabeth Hunter, Patrick Dicker, Zarko Alfirevic, Ella Flemyng, Sarah Lensen, Emma Sydenham, Ginny Barbour, Emily Lam, Gideon Meyerowitz-Katz, James Heathers, Nicholas J L Brown, John Carlisle, Steph Grohmann, Barbara K Redman, Lene Seidler, Kyle A Sheldrick

“…The INveStigating ProblEmatic Clinical Trials in Systematic Reviews (INSPECT-SR) project will develop a tool to assess the trustworthiness of RCTs in systematic reviews of healthcare-related interventions.Methods and analysis The INSPECT-SR tool will be developed using expert consensus in combination with empirical evidence, over five stages: (1) a survey of experts to assemble a comprehensive list of checks for detecting problematic RCTs, (2) an evaluation of the feasibility and impact of applying the checks to systematic reviews, (3) a Delphi survey to determine which of the checks are supported by expert consensus, culminating in, (4) a consensus meeting to select checks to be included in a draft tool and to determine its format and (5) prospective testing of the draft tool in the production of new health systematic reviews, to allow refinement based on user feedback. …”
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Development and retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies: study protocol by Martin Eklund, Brett Delahunt, Lars Egevad, Hemamali Samaratunga, Mattias Rantalainen, Marcello Gambacorta, Einar Gudlaugsson, Bodil Ginnerup Pedersen, Xiaoyi Ji, Karina Dalsgaard Sørensen, Kelvin Szolnoky, Nita Mulliqi, Anders Blilie, Henrik Olsson, Matteo Titus, Geraldine Martinez Gonzalez, Sol Erika Boman, Masi Valkonen, Svein Reidar Kjosavik, José Asenjo, Paolo Libretti, Marcin Braun, Radzislaw Kordek, Roman Łowicki, Kristina Hotakainen, Päivi Väre, Benedicte Parm Ulhøi, Pekka Ruusuvuori, Toyonori Tsuzuki, Emilius Adrianus Maria Janssen, Kimmo Kartasalo

“…Similar challenges complicate the assessment of other prognostic features like cribriform cancer morphology and perineural invasion. …”
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European standard clinical practice recommendations for newly diagnosed ependymoma of childhood and adolescence by Alba Rubio-San-Simón, Timothy A. Ritzmann, Denise Obrecht-Sturm, Martin Benesch, Beate Timmermann, Pierre Leblond, John-Paul Kilday, Geraldina Poggi, Nicola Thorp, Maura Massimino, Marie-Lise van Veelen, Martin Schuhmann, Ulrich-Wilhelm Thomale, Stephan Tippelt, Ulrich Schüller, Stefan Rutkowski, Richard G. Grundy, Stephanie Bolle, Ana Fernández-Teijeiro, Kristian W. Pajtler

“…An integrated diagnosis requires a combination of histological and molecular features as well as tumour localization. Staging with pre- and early post-surgery magnetic resonance imaging of the neuraxis, accompanied by cerebrospinal fluid (CSF) analysis 14 days post surgery must be performed. …”
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Carbon-rich Dust Injected into the Interstellar Medium by Galactic WC Binaries Survives for Hundreds of Years by Noel D. Richardson, Micaela Henson, Emma P. Lieb, Corey Kehl, Ryan M. Lau, Peredur M. Williams, Michael F. Corcoran, J. R. Callingham, André-Nicolas Chené, Theodore R. Gull, Kenji Hamaguchi, Yinuo Han, Matthew J. Hankins, Grant M. Hill, Jennifer L. Hoffman, Jonathan Mackey, Anthony F. J. Moffat, Benjamin J. S. Pope, Pragati Pradhan, Christopher M. P. Russell, Andreas A. C. Sander, Nicole St-Louis, Ian R. Stevens, Peter Tuthill, Gerd Weigelt, Ryan M. T. White

“…We present new JWST imaging of four additional WCd systems (WR 48a, WR 112, WR 125, and WR 137) that were imaged in 2024. In this analysis, we show that the dust is long-lived, detected with an age of at least 130 yr, but more than 300 yr in some systems. …”
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The burden of a new coronavirus infection in a Children’s multidisciplinary hospital in St. Petersburg 2020–2021 by E. A. Dondurei, V. А. Kondratev, L. N. Isankina, N. Yu. Kaika, Yu. A. Gaist, V. V. Yesikov, I. M. Kosenko, V. A. Kaziakhmedov, K. V. Pshenisnov, O. V. Zabirova, S. I. Dvorak, L. V. Ivanova, O. O. Osipova, O. I. Afanasyeva, D. A. Lioznov

“…The analysis of the underlying condition’s structure depending on the severity of the disease, as well as the need and volume of therapy in the intensive care unit. …”
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The ALMA-CRISTAL Survey: Weak Evidence for Star-formation-driven Outflows in z ∼ 5 Main-sequence Galaxies by Jack E. Birkin, Justin S. Spilker, Rodrigo Herrera-Camus, Rebecca L. Davies, Lilian L. Lee, Manuel Aravena, Roberto J. Assef, Loreto Barcos-Muñoz, Alberto Bolatto, Tanio Diaz-Santos, Andreas L. Faisst, Andrea Ferrara, Deanne B. Fisher, Jorge González-López, Ryota Ikeda, Kirsten Knudsen, Juno Li, Yuan Li, Ilse de Looze, Dieter Lutz, Ikki Mitsuhashi, Ana Posses, Monica Relaño, Manuel Solimano, Ken-ichi Tadaki, Vicente Villanueva

“…Excluding sources with kinematic evidence for gravitational interactions, we perform a rigorous stacking analysis of the remaining 15 galaxies to search for broad emission features that are too weak to detect in the individual spectra, finding only weak evidence that a broad component is needed to explain the composite spectrum. …”
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Comparative Affective Outcomes Associated with Circus Arts Instruction in Quality Physical Education by Adam Woolley, Dean Kriellaars, Natalie Houser

“…Physical literacy self-description, movement valuation and self-esteem were also measured, showing differences that approached significance. Post hoc power analysis revealed appropriate power to detect these differences, making self-descriptive features an unlikely but possible explanation for the differing affective outcomes. …”
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The Kangaroo’s First Hop: The Early Fast Cooling Phase of EP250108a/SN 2025kg by Rob A. J. Eyles-Ferris, Peter G. Jonker, Andrew J. Levan, Daniele Bjørn Malesani, Nikhil Sarin, Christopher L. Fryer, Jillian C. Rastinejad, Eric Burns, Nial R. Tanvir, Paul T. O’Brien, Wen-fai Fong, Ilya Mandel, Benjamin P. Gompertz, Charles D. Kilpatrick, Steven Bloemen, Joe S. Bright, Francesco Carotenuto, Gregory Corcoran, Laura Cotter, Paul J. Groot, Luca Izzo, Tanmoy Laskar, Antonio Martin-Carrillo, Jesse Palmerio, Maria E. Ravasio, Jan van Roestel, Andrea Saccardi, Rhaana L. C. Starling, Aishwarya Linesh Thakur, Susanna D. Vergani, Paul M. Vreeswijk, Franz E. Bauer, Sergio Campana, Jennifer A. Chacón, Ashley A. Chrimes, Stefano Covino, Joyce N. D. van Dalen, Valerio D’Elia, Massimiliano De Pasquale, Nusrin Habeeb, Dieter H. Hartmann, Agnes P. C. van Hoof, Páll Jakobsson, Yashaswi Julakanti, Giorgos Leloudas, Daniel Mata Sánchez, Christopher J. Nixon, Daniëlle L. A. Pieterse, Giovanna Pugliese, Jonathan Quirola-Vásquez, Ben C. Rayson, Ruben Salvaterra, Ben Schneider, Manuel A. P. Torres, Tayyaba Zafar

“…EP250108a is a recently detected example linked to an optical counterpart, SN 2025kg, or “the kangaroo.” …”
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