Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis by Yaqiong Tian, Xuan Zhou, Mi Tian, Lijun Ren, Ruyi Zou, Hanyi Jiang, Miaomiao Xie, Mei Huang, Jingjing Ding, Yin Liu, Jingyu Chen, Min Cao, Hourong Cai

“…COX regression and LASSO algorithm were used to screen featured characteristics. Then nomogram models were constructed, ROC curve, calibration curve and decision curve analysis(DCA) were conducted to evaluate the performance of model. …”
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Development of a relapse-related RiskScore model to predict the drug sensitivity and prognosis for patients with ovarian cancer by Zhixin Jin, Xuegu Wang, Xiang Li, Shasha Yang, Biao Ding, Jiaojiao Fei, Xiaojing Wang, Chengli Dou

“…Subsequently, univariate Cox, least absolute shrinkage and selection operator (LASSO) and stepwise regression analysis were employed to determine independent prognostic genes related to relapse in OC to establish a RiskScore model. …”
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Improving image reconstruction to quantify dynamic whole-body PET/CT: Q.Clear versus OSEM by Sam Springer, Jeremy Basset-Sagarminaga, Tineke van de Weijer, Vera B. Schrauwen-Hinderling, Walter H. Backes, Roel Wierts

“…Abstract Background The introduction of PET systems featuring increased count rate sensitivity has resulted in the development of dynamic whole-body PET acquisition protocols to assess 18F-FDG uptake rate ( $${K}_{i}$$ K i ) using 18F-FDG PET/CT. …”
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Predictive Value of IDEAL-IQ and DWI Imaging Biomarkers for P53 Mutations in Hepatocellular Carcinoma by Wang D, Yin H, Li X, Zhou S, Wang YC

“…Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of each MRI parameter for detecting P53 mutations in HCC, with area under the curve (AUC) compared by Delong’s test.Results: Compared to the non-mutated group, the P53-mutated group (n = 31) showed significantly higher R2* values (34.821 ± 9.980 vs 23.713 ± 5.586, P < 0.001) and lower ADC values (0.760 ± 0.142 vs 0.855 ± 0.130, P = 0.002), while FF values showed no significant difference (P = 0.646). …”
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Genome skimming provides evidence to accept two new genera (Apiaceae) separated from the Peucedanum s.l. by Bo-Ni Song, Chang-Kun Liu, Chang-Kun Liu, Jiao-Jiao Deng, Wei-Yan Tan, Song-Dong Zhou, Xing-Jin He

“…Meanwhile, obvious recognized features for morphology, plastome, and chromosome number for each clade were detected: dorsally compressed and glabrous mericarps with filiform dorsal ribs, winged lateral ribs, numerous vittae in commissure and each furrow, IRa/LSC border falling into rpl23 gene, an overall plastome size of 152,288-154,686 bp, and chromosome numbers of 2n=20 were found in clade A; whereas dorsally compressed and pubescent mericarps with filiform dorsal ribs, winged lateral ribs, numerous vittae in commissure and each furrow, IRa/LSC border falling into the ycf2 gene, an overall plastome size of 146,718-147,592 bp, and chromosome numbers of 2n=22 were discovered in clade B. …”
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CHANGES IN THE DENTAL STATUS OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE by D.V. Emelyanov, T.O. Petrushanko

“…On the basis of the results of many scientific studies it has been indicated that there are common features for pathogenetic mechanisms of formation and development of generalized chronic periodontitis and chronic obstructive pulmonary diseases, cardiovascular diseases, diseases of the digestive system, and others. …”
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Exploring the Role of Allergenic Components in Children with House Dust Mite-Induced Allergic Diseases by Xu Q, Shang Y, Li X, Ran S, Lu M, Cheng L

“…A protein chip method was used to detect specific IgE (sIgE) against HDM components, including Der p 1, Der f 1, Der p 2, Der f 2, Der p 5, Der p 7, Der p 10, Der p 21, and Der p 23.Results: 116/120 (96.67%) exhibited positive reactions to HDM components. …”
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Clinical Characteristics, MAML2 Gene Rearrangement and Prognosis 
of Pulmonary Mucoepidermoid Carcinoma by Jianrong BAI, Meng YAN, Lingchuan GUO, Zhe LEI, Weishuo LIU, Zigui ZOU, Jiao LI, Yushuang ZHENG

“…Conclusions PMEC exhibits distinct clinicopathological features, with MAML2 rearrangement present in approximately half of cases. …”
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Electroencephalographic biomarkers of antibody-mediated autoimmune encephalitis by Lu Sun, Yaping Hu, Jingjing Yang, Lihong Chen, Ying Wang, Wei Liu, Jau-Shyong Hong, Yunhui Lv, Lin Yang, Ying Wang

“…Further ROC curve and binary logistics regression analysis showed moderate to severe abnormal EEG was a risk factor for poor prognosis (OR = 11.942, p < 0.05), with an AUC of 0.756.ConclusionEEG is a sensitive and valuable tool for AE and exhibit common and specific features across different AE subtypes. …”
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Use of Large Language Models to Classify Epidemiological Characteristics in Synthetic and Real-World Social Media Posts About Conjunctivitis Outbreaks: Infodemiology Study by Michael S Deiner, Russell Y Deiner, Cherie Fathy, Natalie A Deiner, Vagelis Hristidis, Stephen D McLeod, Thomas J Bukowski, Thuy Doan, Gerami D Seitzman, Thomas M Lietman, Travis C Porco

“…Despite some discrepancies, the LLMs demonstrated a reliable capacity for nuanced epidemiological analysis across various data sources and compared to humans or between LLMs. …”
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Determining the probability of spondyloarthritis in patients with uveitis by A. A. Godzenko, I. Yu. Razumova, S. I. Glukhova

“…The probability of SpA depends on the clinical features of uveitis.The aim – to develop a prognostic formula for determining the probability of spondyloarthritis in patients with uveitisMethods. 208 patients (pts) (79 men and 129 women) with different forms of uveitis, referred by ophthalmologists to the V.A. …”
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Associations between smartphone GPS data and changes in psychological health and burden outcomes among family caregivers and patients with advanced cancer: an exploratory longitudi... by J. Nicholas Odom, Kyungmi Lee, Erin R. Harrell, Kristen Allen Watts, Avery C. Bechthold, Sally Engler, Frank Puga, Natashia Bibriescas, Arif H. Kamal, Christine S. Ritchie, George Demiris, Alexi A. Wright, Marie A. Bakitas, Andres Azuero

“…After pre-processing raw GPS data into daily GPS features (e.g., time spent at home, distance traveled/day), computing biweekly moving averages and standard deviations, and conducting a principal components analysis (PCA) of the resulting variables, within-person regression models were used to assess associations between changes in PRO measures and changes in PCA scores, with adjusted-R2 as the measure of effect size (small = 0.02, medium = 0.13, large = 0.26). …”
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Emergence of mcr-8.2-mediated colistin resistance in Klebsiella pneumoniae isolated from pediatric diarrhea cases in southern Vietnam by Nga Thi Le, Phuong Hoai Hoang, Quynh Nguyen, Minh Nhat Ha Truong, Chinh Van Dang, Tinh Huu Ho, Phuc Le Hoang, Dinh Quang Truong, Ha Thi Thanh Nguyen, Chuong Van Le, Trang Thi Phuong Phan

“…Genomic analysis revealed 34 antibiotic resistance genes, including mcr-8.2 and multiple β-lactamase genes, alongside plasmid types IncFIB and IncFII. …”
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Circular RNA hsa_Circ_0007552 inhibits lung adenocarcinoma proliferation, migration and invasion via the miR-7974/BAP1 axis by Yanping Lin, Rong Li, Xin Shen, Mingjin Wu, Jiadai Tang, Jiangyan Guo, Caixin Yin, Tingrong Xia, Dongqi Li, Fengdi Hu, Yedan Liao, Rui Li, Lin Xie

“…Western blot was performed to detect the protein expression of BAP1.ResultsCirc_0007552 exhibited low expression in LUAD tissues and cells, correlating with clinicopathological features such as tumor size, lymph node metastasis, clinical stage, and poor prognosis. …”
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Development of a cuproptosis-related prognostic signature to reveal heterogeneity of the immune microenvironment and drug sensitivity in acute lymphoblastic leukemia by Bingxin Zhang, Shuxia Zhu, Dong Zheng, Xinyi Zhang, Wenxia Xie, Shujuan Zhou, Sisi Zheng, Quanqiang Wang, Zhili Lin, Ziwei Zheng, Zixing Chen, Enqing Lan, Luning Cui, Hansen Ying, Yu Zhang, Xuanru Lin, Qiang Zhuang, Honglan Qian, Xudong Hu, Yan Zhuang, Qianying Zhang, Zhouxiang Jin, Songfu Jiang, Yongyong Ma

“…Lastly, qRT-PCR was used to detect prognostic genes in cell lines and clinical samples. …”
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The Catalogue of Gamma-Ray Burst Observations by HEPD-01 in the 0.3–50 MeV Energy Range by S. Bartocci, R. Battiston, S. Beolè, W. J. Burger, D. Campana, P. Cipollone, A. Contin, M. Cristoforetti, C. De Donato, C. De Santis, A. Di Luca, F. M. Follega, G. Gebbia, R. Iuppa, A. Lega, M. Lolli, M. Martucci, G. Masciantonio, M. Mergè, M. Mese, C. Neubüser, R. Nicolaidis, F. Nozzoli, A. Oliva, G. Osteria, F. Palma, B. Panico, F. Perfetto, A. Perinelli, P. Picozza, E. Ricci, L. Ricci, M. Ricci, S. B. Ricciarini, Z. Sahnoun, U. Savino, V. Scotti, M. Sorbara, A. Sotgiu, R. Sparvoli, P. Ubertini, V. Vilona, S. Zoffoli, P. Zuccon

“…The present work reports a comprehensive analysis of signals induced by GRBs in the event-rate data collected between 2018 August and 2022 June. …”
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Virus-human chromatin interactions reorganise 3D genome and hijack KDM5B for promoting metastasis in nasopharyngeal carcinoma by Dittman Lai-Shun Chung, Zhaozheng Hou, Ying Wang, Kazi Anisha Islam, Songran Liu, Jiayan Liu, Larry Ka-Yue Chow, Yuki Yuk-Wun Wong, Cyrus Paak-Ting Chak, Yingpei Zhang, Lanqi Gong, Ziyang Qi, Kiu-Wai Cheng, Zhuoyou Yu, Ping Feng, Zilu Huang, Roger Kai-Cheong Ngan, Xinyuan Guan, Wai-Tong Ng, Zhonghua Liu, Anna Chi-Man Tsang, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Victor Ho-Fun Lee, Honglin Chen, Yunfei Xia, Wei Dai

“…Abstract Epstein–Barr virus, the first identified human DNA tumour virus, is detectable in more than 90% of nasopharyngeal carcinoma patients in endemic regions. …”
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PD-L1 levels, TP53 mutation profiles, and survival outcomes in pancreatic cancer differ by immune-nutritional status by Zheng Li, Hu Ren, Shihui Zhang, Chongyuan Sun, Zefeng Li, Penghui Niu, He Fei, Cheng Xing, Susheng Shi, Dongbing Zhao

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) frequently exhibits an immunosuppressive microenvironment coupled with malnutrition status. These features are instrumental in clinical management strategies for PDAC. …”
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Gradual changes within long-lived influenza virus-specific CD8+ T cells are associated with the loss of public TCR clonotypes in older adultsResearch in context by Carolien E. van de Sandt, Hayley A. McQuilten, Malet Aban, Thi H.O. Nguyen, Sophie A. Valkenburg, Emma J. Grant, Sneha Sant, Jamie Rossjohn, Stephanie Gras, Jane Crowe, Katherine Kedzierska

“…Funders had no role in design, analysis or reporting of the study.…”
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Gain-of-function ANXA11 mutation cause late-onset ALS with aberrant protein aggregation, neuroinflammation and autophagy impairment by Qing Liu, Ye Sun, Baodong He, Haodong Chen, Lijing Wang, Gaojie Wang, Kang Zhang, Ximeng Zhao, Xinzhe Zhang, Dongchao Shen, Xue Zhang, Liying Cui

“…This study examines the clinical features of ALS patients harboring the ANXA11 hotspot mutation p.P36R, characterized by late-onset motor neuron disease and occasional multi-system involvement. …”
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