Hyalinizing clear cell carcinoma of the lung: a case report and literature review by Yu-Ju Su, Yun-Shao Wu, Cheng-Hung How, Min-Shu Hsieh

“…Abstract Background Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is an exceedingly rare tumor with unique clinicopathological features, posing major diagnostic challenges. Case presentation We present a case of a 74-year-old woman with a lung nodule incidentally detected in the right middle lobe (RML) through 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging. …”
Get full text

De novo variant in GUCY2D gene causing atypical cone-rod dystrophy in a consanguineous family and literature review by Xin-He Fang, Fa-Yong Ke, Wen-Qing Zou, De-Jun Zhu, Mei-Jiao Ma, Yuan-Yuan Lian, Xue-Li Wu, Rui-Hua Wei, Xun-Lun Sheng

“…Sanger sequencing co-segregation analysis confirmed that such a variant was detected in neither the phenotypically normal parents nor the daughter of the proband, which was presumed to be a de novo one. …”
Get full text

Determinants of conventional and contrast-enhanced ultrasound diagnosis of fat-poor angiomyolipoma <5 cm by Xia Liang, Xia Liang, Xia Liang, Xian-Tao Zeng, Xian-Tao Zeng, Xian-Tao Zeng, Zhi-Liang Hong, Zhi-Liang Hong, Zhi-Liang Hong, Miao-Jiao Su, Miao-Jiao Su, Miao-Jiao Su, Jian-Chuan Yang, Jian-Chuan Yang, Jian-Chuan Yang, Song-Song Wu, Song-Song Wu, Song-Song Wu

“…We systematically analyzed the features observed in CUS and CEUS, identified independent factors through multifactorial regression analysis, and evaluated diagnostic efficacy by calculating the area under the curve (AUC).ResultsUnivariate analysis revealed significant distinctions in fat-poor AML concerning gender, age, morphology, internal hyperechoic features (starry-sky sign, crescent sign), enhancement uniformity, and delayed enhancement, all displaying significance compared to renal cell carcinoma (RCC) (p &lt; 0.05). …”
Get full text

Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization. by Rituparna Mukhopadhyay, Julien Lajugie, Nicolas Fourel, Ari Selzer, Michael Schizas, Boris Bartholdy, Jessica Mar, Chii Mei Lin, Melvenia M Martin, Michael Ryan, Mirit I Aladjem, Eric E Bouhassira

“…Biased chromosome X inactivation in one of the two individuals tested was another source of detectable replication asynchrony. Analysis of high-resolution TimEX profiles revealed small variations termed timing ripples, which were undetected in previous, lower resolution analyses. …”
Get full text

Veps Wedding Terminology in the Etymological and Linguo-Geographical Aspects (Veps vs. Russian) by N. G. Zaitseva, O. Yu. Zhukova

“…It is shown that these dialects are characterized by the conservation of archaic characters, the presence of rare (in this case, sai) and etymologically darkened (oluh) lexical items, which so far have not been able to detect etymons in related languages. The authors believe that this fact, coupled with other features of dialects, may indicate traces of the substrate, the origins of which have yet to be clarified.…”
Get full text

Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts. by Junpeng Gao, Yuxuan Zheng, Lin Li, Minjie Lu, Xiangjian Chen, Yu Wang, Yanna Li, Xiaomeng Liu, Yun Gao, Yunuo Mao, Peng Zhao, Jinan Zhang, Fuchou Tang, Lei Song, Lu Wen, Jizheng Wang

“…DNA methylation, chromatin accessibility, and gene expression represent different levels information in biological process, but a comprehensive multiomics analysis of the mammalian heart is lacking. Here, we applied nucleosome occupancy and methylome sequencing, which detected DNA methylation and chromatin accessibility simultaneously, as well as RNA-seq, for multiomics analysis of the 4 chambers of adult and fetal human hearts, and adult mouse hearts. …”
Get full text

Influence of the Level of Defective Insulation Resistance of Electrical Machine Windings on Parameters of no-Load Current by A. V. Isaev, Yu. V. Suhodolov, S. V. Sizikov, A. A. Lomtev, V. A. Lychkovsky

“…Diagnostic methods that will change at present for monitoring the condition of windings of electric machines do not allow to detect defect formation in them at early stages of development. …”
Get full text

Corruption in the Local Government System of the Russian State (According to Investigative Cases of the 1590–1630s) by Vladimir Arakcheev

“…Methods and materials. The subject of the analysis is three investigative cases of corruption revealed during the 1590–1630s in three regions of Russia: Veliky Novgorod, Pskov, and Sviyazhsk. …”
Get full text

Evaluating anti-VEGF responses in diabetic macular edema: A systematic review with AI-powered treatment insights by S Tamilselvi, M Suchetha, Dhanashree Ratra, Janani Surya, S Preethi, Rajiv Raman

“…Recent advances in deep learning and machine learning have greatly increased the capabilities of extracting features for evaluating the response to anti VEGF treatment in patients with Diabetic Macular Edema (DME). …”
Get full text

The Contribution to the Integration of Management Systems Oriented to the Sustainable and TQM by Věra Pelantová, Eva Šlaichová

“…Based on the results of the literature research, according to the analysis of the state of management systems in the selected organisations and according to the experience of authors, it sets out the basic features for an integrated management system aimed at sustainability and social responsibility. …”
Get full text

The Abnormal Diagnosis Method for Process Parameter Fluctuation Based on Power Spectral Density and Statistical Characteristics by Zhu Wang, Jiale Zhan, Qinghe Zheng, Shaokang Zhang

“…We employ a combined analysis of power spectral density and statistical characteristics to extract features from multitude of incremental data. …”
Get full text

JAG1 MUTATION SPECTRUM IN CASES WITH ALAGILLE SYNDROME FROM TURKIYE by Ayça Dilruba Aslanger, Behiye Tuğçe Yıldırım, Tuğba Kalaycı, Leyli Şentürk, Şahin Avcı, Umut Altunoğlu, Çağrı Güleç, Volkan Karaman, Güzide Doğan, Zerrin Önal, Özlem Durmaz, Birsen Karaman, Zehra Oya Uyguner

“…Karyotype, fluorescence in situ hybridization (FISH), array comparative genomic hybridization (aCGH), and JAG1 gene sequencing utilizing next-generation and Sanger sequencing methodologies were conducted.Result: The presence of both large deletion and small variants associated with Alagille syndrome was detected in all cases. In karyotype and aCGH analysis of a single case, a gross 20p deletion was identified. …”
Get full text

BENEFITS OF USE OF ACOUSTIC EMISSION IN SCRATCH TESTING by Lukáš Václavek, Jan Tomáštík, Hana Chmelíčková, Radim Čtvrtlík

“…By default, its evaluation is based on analysis of depth-load-time record and microscopic observation of residual scratch groove. …”
Get full text

Gravitational-wave effects in the most general vector–tensor theory by Yu-Qi Dong, Xiao-Bin Lai, Yu-Qiang Liu, Yu-Xiao Liu

“…These features are closely tied to observable phenomena and have attracted considerable attention. …”
Get full text

Cochlear Implantation in a Patient with a Novel POU3F4 Mutation and Incomplete Partition Type-III Malformation by Xiuhua Chao, Yun Xiao, Fengguo Zhang, Jianfen Luo, Ruijie Wang, Wenwen Liu, Haibo Wang, Lei Xu

“…A patient who was diagnosed as the IP-III malformation underwent cochlear implantation in our hospital. The genetic analysis was conducted in his family, including the whole-exome sequencing combined with Sanger sequencing and bioinformatic analysis. …”
Get full text

The value of triglyceride–glucose index–related indices in evaluating migraine: perspectives from multi–centre cross–sectional studies and machine learning models by Zixuan Yan, Lincheng Duan, Hong Yin, Muchen Wang, Jingwen Li, Chenghua Li, Xiao Wang, Dingjun Cai, Fanrong Liang, Wenchuan Qi

“…SHapley Additive Explanations (SHAP) values were used to analyze leading models, highlighting influential features. Results The analysis included 6,204 U.S. participants and 9,401 Chinese participants. …”
Get full text

IMAGE PROCESSING MODELS AND METHODS RESEARCH AND WAYS OF IMPROVING MARKER RECOGNITION TECHNOLOGIES IN ADDED REALITY SYSTEMS by Nataliia Bolohova, Igor Ruban

“…The next results were obtained: a review and a comparative analysis of the main known algorithms for detecting key points in the images were conducted. …”
Get full text

Investigating soil mesofauna cryptic diversity: Current challenges and perspectives by Margarita A. Danilova, Elena Y. Zvychaynaya, Polina A. Guseva, Andrey S. Zaitsev

“…Abstract Cryptic species lacking distinct morphological features are widespread among soil fauna, including such functionally significant groups as springtails, mites and enchytraeids. …”
Get full text

Moxibustion ameliorates abnormal subchondral bone remodeling by promoting ACSL1-mediated autophagy to degrade NLRP3 in osteoarthritis by Xuelan Chen, Liping Fu, Yu Huang, Qing Liao, Binhua Zou, Lixia Yuan, Gang Liu

“…The effects of moxibustion on knee osteoarthritis symptoms and walking ability were assessed by knee joint diameter measurement, von Frey test and footprint analysis. Micro-CT, TEM, immunofluorescence staining, and western blot were used to detect the contact between autophagy–lysosomal pathway and NLRP3 inflammasome in subchondral bone remodeling. …”
Get full text

Polymorphism of angiogenesis regulation factor genes (<i>VEGF/VEGFR</i>), and extracellular matrix remodeling genes (<i>MMP/TIMP</i>), and the levels of their products in extracell... by V. I. Konenkov, V. V. Nimaev, A. V. Shevchenko, V. F. Prokofiev

“…The aim of the work was to perform: a comparative analysis of some polymorphisms of vascular endothelial growth factor and their receptors and the genes encoding matrix metalloproteinases in two forms of lymphedema; an analysis of the relationship of these genes’ polymorphisms with the levels of vascular endothelial growth factor and matrix metalloproteinases and their inhibitors in serum and affected tissues. …”
Get full text