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4561
Breast lesion classification via colorized mammograms and transfer learning in a novel CAD framework
Published 2025-07-01“…As a result, Computer-Aided Design (CAD) systems have become increasingly popular due to their ability to operate independently of human analysis. Current CAD systems use grayscale analysis, which lacks the contrast needed to differentiate benign from malignant lesions. …”
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4562
High-throughput untargeted metabolomics reveals metabolites and metabolic pathways that differentiate two divergent pig breeds
Published 2025-01-01“…The molecular data were analysed using a bioinformatics pipeline specifically designed for identifying differentially abundant metabolites between the two breeds in a robust and statistically significant manner, including the Boruta algorithm, which is a Random Forest wrapper, and sparse Partial Least Squares Discriminant Analysis (sPLS-DA) for feature selection. After thoroughly evaluating the impact of random components on missing value imputation, 100 discriminant metabolites were selected by Boruta and 17 discriminant metabolites (all included within the previous list) were identified with sPLS-DA. …”
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4563
Role of hepcidin in the development of anemia in patients with rheumatoid arthritis
Published 2012-06-01“…As earlier noted, iron metabolic disturbances in CDA are its diagnostic feature and the discovery of hepcidin, an iron-regulatory acute-phase protein, could largely clarify an association between the immune mechanism of impaired iron homeostasis and the development of CDA. …”
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4564
Flourishing in Darkness: Protist Communities of Water Sites in Shulgan-Tash Cave (Southern Urals, Russia)
Published 2024-09-01“…However, no potentially harmful fungi were detected, positioning this research as a baseline for future monitoring. …”
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4565
Subclinical Aortic Root Pathology in Close Relatives of Patients with Bicuspid Aortic Valve
Published 2013-12-01“…Bicuspid aortic valve (BAV) is a widespread structural anomaly of the heart that occurs at a frequency of 0.9-1.5% in the general population. As usual, this feature of the structure of the valve is combined with the expansion of the ascending part of the aorta. …”
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4566
Damage Identification Using Measured and Simulated Guided Wave Damage Interaction Coefficients Predicted Ad Hoc by Deep Neural Networks
Published 2025-03-01“…Additionally, an anglewise principal component analysis is proposed to efficiently reduce the feature dimensionality on average by more than <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>90</mn><mo>%</mo></mrow></semantics></math></inline-formula> while accounting for the angular dependencies of the WDICs. …”
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4567
Mycotoxin Challenge in Dairy Cows: Assessment of the Efficacy of an Anti-Mycotoxin Agent by Adopting an In Vitro Rumen Simulation Method
Published 2024-11-01“…However, the complex interactions between the mycotoxin, the ruminal environment, and the anti-mycotoxin agent made it difficult to establish a clear dose–effect relationship (<i>p</i> > 0.10). UHPLC-HRMS analysis identified over 1500 mass features in rumen samples, which were further analyzed to assess the effects of the anti-mycotoxin agent. …”
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4568
Clinical characteristics and factors associated with the severity of hand, foot, and mouth disease in Mekong Delta, Vietnam
Published 2025-12-01“…Background Hand, foot, and mouth disease (HFMD) is a contagious viral illness caused by enteroviruses, potentially leading to severe complications like encephalitis, myocarditis, and acute pulmonary edema.Objective This study examines clinical features and risk factors for HFMD severity.Materials and Methods A cross-sectional analysis of 200 children under 16 years.Results Oral ulcers (78.0%) and erythematous rashes (64.0%) as the most common symptoms. …”
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4569
Extracellular Membrane Vesicles and Phytopathogenicity of Acholeplasma laidlawii PG8
Published 2012-01-01“…Data on the ability of extracellular vesicles of Acholeplasma laidlawii PG8 to penetrate from the nutrient medium into overground parts of Oryza sativa L. through the root system and to cause alterations in ultrastructural organization of the plants were presented. As a result of the analysis of ultrathin leaf sections of plants grown in medium with A. laidlawii PG8 vesicles, we detected significant changes in tissue ultrastructure characteristic to oxidative stress in plants as well as their cultivation along with bacterial cells. …”
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4570
Genome-wide profiling of DNA repair proteins in single cells
Published 2024-11-01“…Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detection has remained challenging. Here, we present a comprehensive analysis of repair protein localization in single human cells using DamID and ChIC sequencing techniques. …”
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4571
Online Pre-Diagnosis of Multiple Faults in Proton Exchange Membrane Fuel Cells by Convolutional Neural Network Based Bi-Directional Long Short-Term Memory Parallel Model with Atten...
Published 2025-05-01“…To address these gaps, this study proposes an online multi-fault prediction framework integrating three novel contributions: (1) a sensor fusion strategy leveraging existing thermal/electrochemical measurements (voltage, current, temperature, humidity, and pressure) without requiring embedded stack sensors; (2) a real-time sliding window mechanism enabling dynamic prediction updates every 1 s under variable load conditions; and (3) a modified CNN-based Bi-LSTM parallel model with attention mechanism (ConvBLSTM-PMwA) architecture featuring multi-input multi-output (MIMO) capability for simultaneous flooding/air-starvation detection. …”
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4572
Exploring the Spectral Variability of Estonian Lakes Using Spaceborne Imaging Spectroscopy
Published 2025-07-01“…Hyperspectral imagery successfully captured fine-scale spatial and spectral features not detectable by multispectral sensors, in particular it was possible to identify cyanobacterial pigments and optical variations driven by seasonal and meteorological dynamics. …”
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4573
Advancements in the integration of isothermal nucleic acid amplification methods for point-of-care testing in resource-limited settings
Published 2025-06-01“…We then examine the unique features of POC systems, such as the use of low-cost materials for device fabrication, portability, and detection methods that provide rapid and reliable results near the site of patient care. …”
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4574
Differential diagnosis of juvenile idiopathic arthritis and multiple epiphyseal dysplasia: Experience of multidisciplinary interaction
Published 2023-10-01“…Despite the significant overlap of the clinical symptoms between JIA and MED, the key to the early diagnosis of MED is a comprehensive examination, which included genealogical analysis, features of clinical manifestations and disease course in combination with distinctive radiological signs including delayed ossification of the epiphyses of tubular bones typical for MED. …”
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4575
Lightning identification based on multiple weather radar product data
Published 2025-08-01“…In this model, five types of radar product data are fused into a multi-feature radar image through a Principal Component Analysis Weighted Average Fusion method, which serves as the model’s input. …”
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4576
Dynamic Event-Triggered-Based Finite-Time Distributed Tracking Control of Networked Multi-UAV Systems
Published 2025-01-01“…Theoretically, a dynamic event-triggered mechanism is proposed, which features a novel finite-time stable dynamic variable within its triggering rule, ensuring that neither controller updates nor trigger detection requires continuous communication. …”
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4577
Multi-Subject Remote Heart Sound Monitoring Using mmWave MIMO RADAR
Published 2025-01-01“…A complete RADAR signal processing chain is developed, incorporating automatic subject detection and localization using temporal features, spatial beamforming to separate signals from multiple subjects, and heart sound signal extraction. …”
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4578
Long-read sequencing reveals absence of 5mC in Ogataea parapolymorpha DL-1 genome and introduces telomere-to-telomere assembly
Published 2025-05-01“…The genome was analyzed to identify coding genes, telomeric motifs, rRNA genes, and methylation patterns, including the detection of 5mC and 6 mA modifications. Epigenetic features were further assessed and validated through liquid chromatography-mass spectrometry.ResultsKey findings include the absence of 5 mC DNA modification and the presence of 6 mA in the genome, unusual telomere regulation mechanism based on the addition of non-telomeric dT and the introduction of long-read enhanced telomere-to-telomere assembly.ConclusionThis work provides deeper insights into the yeast’s genome organization and methylation patterns, contributing to the understanding of its genetics and therefore potential biotechnological applications.…”
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4579
Study of Clinical Characteristics of AIDS Patients With Opportunistic Infections: Findings From Cut Mutia General Hospital
Published 2025-01-01“…Data included demographic profiles, clinical features, types of OIs, and treatment outcomes. Descriptive statistical analysis was performed. …”
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4580
A nomogram model integrating radiomics and clinical variables to predict napsin a expression in lung adenocarcinoma patients
Published 2025-07-01“…BackgroundLung adenocarcinoma, a major subtype of non-small cell lung cancer, requires non-invasive diagnostic tools to improve early detection and differentiate primary from metastatic tumors. …”
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