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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth
Published 2024-12-01“…Background Granzyme B (GrB) is a key effector molecule, delivered by cytotoxic T lymphocytes and natural killer cells during immune surveillance to induce cell death. …”
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Acoustic Characterization of Fluorinert FC-43 Liquid with Helium Gas Bubbles: Numerical Experiments
Published 2017-01-01Get full text
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Identification of novel anti-CD16a antibody clones for the development of effective natural killer cell engagers
Published 2024-12-01“…Natural killer (NK) cells are key players in human innate immunity. …”
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TRANSPARENCY METERS AND GAS ANALYZERS BASED ON TWO-WAVELENGTH SEMICONDUCTOR LASERS
Published 2015-04-01Get full text
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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques
Published 2024-12-01“…To reach protective levels in fetuses, mAbs must be transported across the placenta, a selective barrier that actively and specifically promotes the transfer of antibodies (Abs) into the fetus through the neonatal Fc receptor (FcRn). Because FcRn also regulates Ab half-life, Fc mutations like the M428L/N434S, commonly known as LS mutations, and others have been developed to enhance binding affinity to FcRn and improve drug pharmacokinetics. …”
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THE EVOLUTION OF THE NATURAL PROTECTED AREAS NETWORK IN ROMANIA
Published 2012-07-01Get full text
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Handbook of Florida Water Regulation: Florida Watershed Restoration Act
Published 2019-05-01Get full text
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Lateral Condyle Fracture of the Humerus in Children Treated with Bioabsorbable Materials
Published 2013-01-01Get full text
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MXene-based materials for enhanced water quality: Advances in remediation strategies
Published 2025-02-01Get full text
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Development and Application of Fluid-Solid Coupling Similar Materials in Discharge Test of Old Goaf Water
Published 2020-01-01Get full text
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Development of a Cloud-Point Extraction Method for Cobalt Determination in Natural Water Samples
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Denial of Human Superiority Over Nature as the Denial of the Value of Nature
Published 2022-01-01Get full text
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