Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy by Xiaojie Liang, Jia Guo, Baiwei Luo, Weixiang Lu, Qiumin Chen, Yeling Deng, Yunong Yang, Liang Wang

“…Methods Using data from multiple researches, we comprehensively evaluated the characteristics and prognostic impact of PSI features in DLBCL, and developed a novel risk stratification model (PSI score) with a consistent cutoff value to stratify the risk of 3,229 DLBCL patients from different cohorts. …”
Get full text

Effect of perioperative esketamine use on emergency delirium in children undergoing tonsillectomy and adenoidectomy: a systematic review and meta-analysis of randomized controlled... by Junfeng Liu, Jinming Liu, Hong Sun, Xue Cheng, Chunhui Wang, Daoyun Lei, Chao Han

“…Scores of ED were lower in the esketamine group than in the control group (SMD = -1.20, 95% CI: [−1.56,-0.84], p < 0.00001, I2 = 88%). …”
Get full text

The influence of meteorological factors on the technical performance of football teams during matches by Yonghan Zhong, Shaoliang Zhang, Qing Yi, Miguel Ángel Gómez Ruano

“…Thirty-one technical actions and events were categorized into three groups (goal scoring, offense, and defence). Meteorological data were collected from the official UEFA website (air temperature (°C): 11.59 ± 6.87, relative humidity (%): 71.40 ± 17.82, wind speed (km/h): 11.52 ± 7.02). …”
Get full text

Assessment of Oxidative Stress by the Estimation of Lipid Peroxidation Marker Malondialdehyde (MDA) in Patients with Chronic Periodontitis: A Systematic Review and Meta-Analysis by Khadijah Mohideen, Krithika Chandrasekar, Saranya Ramsridhar, Chandini Rajkumar, Snehashish Ghosh, Safal Dhungel

“…Out of these, 16 articles had coherent data for quantitative synthesis. The meta-analysis used the standardized mean differences method at a 95% confidence interval by random-effects model. …”
Get full text

Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar... by Rohan Khera, Yuan Lu, Harlan M Krumholz, Martijn J Schuemie, Ruijun Chen, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets

Get full text

Statistical analysis based on a two-staged SEM-SVM approach for environmental noise annoyance prediction and identification of influencing factors by M. Rehman, M. Kamal, S. Tiwari

“…The performance of the Support Vector Machine model was evaluated using Root Mean Square Error, Mean Absolute Error, and R-squared.FINDINGS: The Structural Equation Model analysis revealed that gender, age, education level, traffic flow, noise from traffic, and individual noise sensitivity were significant contributors to noise annoyance. …”
Get full text

Semantic analysis of test items through large language model embeddings predicts a-priori factorial structure of personality tests by Nicola Milano, Maria Luongo, Michela Ponticorvo, Davide Marocco

“…In this article, we explore the use of Large Language Models (LLMs) for predicting factor loadings in personality tests through the semantic analysis of test items. By leveraging text embeddings generated from LLMs, we evaluate the semantic similarity of test items and their alignment with hypothesized factorial structures without depending on human response data. …”
Get full text

Comprehensive Analysis of Gene Signatures of m6ARNA Methylation Regulators in Lung Adenocarcinoma and Development of a Risk Scoring System by Chundi Gao, Huayao Li, Wenzhe Ma, Qiming Zhang, Cun Liu, Lijuan Liu, Jing Zhuang, Changgang Sun

Get full text

A Survey on the Effect of Livestock Production System and Finishing Diet on Sensory Characteristics of Foal Meat Using Generalized Procrustes Analysis by José M. Lorenzo, Laura Purriños, Javier Carballo

“…Data were analyzed using a GPA to minimize differences among testers. …”
Get full text

Bioinformatics and Deep Learning Approach to Discover Food-Derived Active Ingredients for Alzheimer’s Disease Therapy by Junyu Zhou, Chen Li, Yong Kwan Kim, Sunmin Park

“…We employed the bioinformatics-integrated deep neural analysis of NCs for Disease Discovery (BioDeepNat) application in the data collected from chemical databases. …”
Get full text

Application of Surface Roughness Analysis on Micro–Computed Tomographic Images of Bone Erosion: Examples Using a Rodent Model of Rheumatoid Arthritis by Matthew D. Silva, Jason Ruan, Elizabeth Siebert, Anneli Savinainen, Bruce Jaffee, Lisa Schopf, Sudeep Chandra

Get full text

Tear Strength Analysis of MDX4-4210 and A-2186 Silicones with Different Intrinsic Pigments Incorporated by Mechanical and Industrial Methods by Marcelo Coelho Goiato, Adhara Smith Nobrega, Emily Vivianne Freitas da Silva, Daniela Micheline dos Santos, André Pinheiro de Magalhães Bertoz, Mariana Vilela Sonego, Clovis Lamartine de Moraes Melo Neto

“…The aim of this study was to evaluate the tear strength of MDX4-4210 and A-2186 silicones with different intrinsic pigments incorporated by mechanical and industrial methods, comparing nonaged and aged groups. …”
Get full text

The impact of glucagon-like peptide-1 (GLP-1) agonists in the treatment of eating disorders: a systematic review and meta-analysis by Hanieh Radkhah, Shiva Rahimipour Anaraki, Peyvand Parhizkar Roudsari, Razman Arabzadeh Bahri, Diar Zooravar, Sara Asgarian, Reza Hosseini Dolama, Ali Alirezaei, Razieh Khalooeifard

Get full text

Patients’ satisfaction and efficacy of modern conventional hearing aids: A comprehensive analysis of the self-reported user experiences in adult people by Daniele Portelli, Cosimo Galletti, Sabrina Loteta, Leonard Freni, Francesco Ciodaro, Angela Alibrandi, Giuseppe Alberti

“…Patients were divided into two groups based on this median age and sex for comparative analysis. …”
Get full text

A theory-based analysis of the implementation of online asynchronous telemedicine platforms into primary care practices using Normalisation Process Theory by Cara Leighton, Natalie Joseph-Williams, Annavittoria Porter, Adrian Edwards, Alison Cooper

Get full text

Outcomes and physiologic responses associated with ketamine administration after traumatic brain injury in the United States and Canada: a retrospective analysis by Austin J. Peters, Saad A. Khan, Seiji Koike, Susan Rowell, Martin Schreiber

“…Methods We performed a retrospective analysis of data from the multicenter Prehospital Tranexamic Acid Use for Traumatic Brain Injury trial, comparing ketamine-exposed and ketamine-unexposed TBI subjects to determine whether an association exists between ketamine administration and mortality, as well as secondary outcome measures. …”
Get full text

Apical extrusion of debris with different rotary and reciprocating single-file endodontic instrumentation systems: a systematic review and meta-analysis protocol by Muhammad Zubair Ahmad, Durre Sadaf, Marcy McCall MacBain, Ahmed Nabil Mohamed

Get full text

Prevalence of potential drug‒drug interactions and associated factors among elderly patients in Ethiopia: a systematic review and meta-analysis by Tekletsadik Tekleslassie Alemayehu, Yilkal Abebaw Wassie, Abaynesh Fentahun Bekalu, Addisu Afrassa Tegegne, Wondim Ayenew, Gebresilassie Tadesse, Demis Getachew, Abebaw Setegn Yazie, Bisrat Birke Teketelew, Mekonnen Derese Mekete, Setegn Fentahun, Tesfaye Birhanu Abebe, Tefera Minwagaw, Gebremariam Wulie Geremew

“…Egger regression tests and funnel plot analysis were used to check publication bias, and the I2 statistic was used to evaluate statistical heterogeneity. …”
Get full text

Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis by Zhang L, Zhao S, Zhao S, Zheng H, Ke Y, Yang W, Lei M

“…Data on demographics, exercise habits, eating patterns, sedentary behavior, psychological health, sleep health, self-esteem, and social support were collected. …”
Get full text

Clinical Efficacy of Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training on Patients with Post Stroke Cognitive Impairment： A Meta-Analysis by LIU Changxing, GUO Xinyi, CHANG Xiang

“…ObjectiveTo evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training on patients with post stroke cognitive impairment (PSCI) by Meta-analysis.MethodsData were searched and retrieved from the databases of PubMed, Embase, The Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Data, and Chinese Science and Technology Periodical Database (VIP). …”
Get full text