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Serum Levels of Mitochondrial Fission- and Fusion-Related Genes of Coal Workers’ Pneumoconiosis and Risk Factor Analysis Based on a Generalized Linear Model
Published 2022-01-01“…We aimed to explore the risk factors for coal workers’ pneumoconiosis and to further explore the significance of mitochondrial fission and fusion factors in CWP and verify the feasibility of mitochondrial fission and fusion factors as diagnostic and therapeutic targets. Methods. The data of 168 cases were collected, and they were divided into a healthy control group (40 cases), dust exposure control group (61 cases), and CWP group (67 cases) and entered into SPSS 24.0. …”
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682
Construction and validation of a predictive model for the risk of myelosuppression after first-line chemotherapy in patients with advanced colorectal cancer
Published 2025-01-01“…Additionally, the model's clinical utility was evaluated using calibration and clinical decision curves.Results A total of 257 patients were included, 112 individuals exhibited bone CIM, corresponding to an incidence rate of 43.58%. …”
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683
Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis
Published 2025-02-01“…The combination of lenvatinib, a multikinase inhibitor, with PD-1 inhibitors has demonstrated significant survival benefits in HCC. This meta-analysis aims to assess whether the integration of HAIC with lenvatinib and PD-1 inhibitors (referred to as the HAIC-L-P group) leads to better treatment effectiveness and security compared to lenvatinib and PD-1 inhibitors alone (L-P group) in uHCC.MethodsAn exhaustive search of the literature was conducted, including PubMed, the Cochrane Library, Embase, ClinicalTrials.gov, and Web of Science, from the start of each database until September 2024, to ensure a thorough and up-to-date compilation of relevant studies. …”
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684
Analysis of Metabolic Risk Factors for Microcirculation Disorders Post-Percutaneous Coronary Intervention and Predictive Model Construction: A Study on Patients with Unstable Angin...
Published 2025-01-01“…The angiographic microcirculatory resistance (AMR) index was calculated based on coronary angiography data. Patients were divided into two groups according to their post-PCI AMR values: a post-PCI AMR ≤2.50 group and a post-PCI AMR >2.50 group. …”
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685
Effect of trilaciclib administered before chemotherapy in patients with extensive-stage small-cell lung cancer: A pooled analysis of four randomized studies
Published 2024-01-01“…Background: Trilaciclib is a transient cyclin-dependent kinase 4/6 (CDK4/6) inhibitor that reduces the incidence of chemotherapy-induced myelosuppression (CIM). In this pooled analysis, we evaluated the multilineage myeloprotection, antitumor efficacy, and safety of trilaciclib treatment in patients with extensive-stage small-cell lung cancer (ES-SCLC). …”
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Value contribution of leniolisib in the Treatment of Activated PI3Kδ syndrome (APDS) in Spain using Multi-Criteria Decision Analysis (MCDA)
Published 2025-01-01“…Methods: A multidisciplinary group of 8 experts evaluated the selective PI3Kδ inhibitor leniolisib against Standard of Care (SoC). …”
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688
Long-Term Follow-Up of Patients with Advanced Colorectal Liver Metastasis: A Survival Analysis from the Randomized Controlled Multicenter Trial LIGRO
Published 2024-09-01“…The 2-year survival analysis revealed better overall survival in the ALPPS group. …”
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Perturbation Theory-Based Whole-Core Eigenvalue Sensitivity and Uncertainty (SU) Analysis via a 2D/1D Transport Code
Published 2020-01-01“…Based on the home-developed 3D high-fidelity neutron transport code HNET, the perturbation theory was used to directly calculate the sensitivity coefficient of keff to the multigroup cross sections, and a reasonable relative covariance matrix with a specific energy group structure was generated directly from the evaluated covariance data by using the transforming method. …”
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691
Analysis of Torque Maintenance and Fracture Resistance after Fatigue in Retention Screws Made of Different Metals for Screw-Retained Implant-Borne Prosthesis Joints
Published 2021-01-01“…The data were tabulated and submitted to appropriate statistical analysis (α = 0.05). …”
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692
Comparison of Different Molecular Weights of Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis: A Level I Bayesian Network Meta-Analysis
Published 2025-01-01“…LMW HA was the intervention associated with the lowest decrease in VAS, falling short of the control group. <b>Conclusions:</b> The main findings of the present Bayesian network meta-analysis, with a current level I of evidence, suggests that the UHMW and HMW HA has a beneficial effect on pain at 6 months post intervention in patients with knee osteoarthritis.…”
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693
Effectiveness of shared decision-making for glycaemic control among type 2 diabetes mellitus adult patients: A systematic review and meta-analysis.
Published 2024-01-01“…The mean differences (MD) of glycated hemoglobin (HbA1c) were pooled using a random effect model (REM), and sub-group analysis were performed to evaluate the effect size differences across the duration of the follow-up period, modes of intervention, and baseline glycated hemoglobin level of patient groups. …”
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694
A network analysis of the propagation of evidence regarding the effectiveness of fat-controlled diets in the secondary prevention of coronary heart disease (CHD): Selective citatio...
Published 2018-01-01“…<h4>Conclusion</h4>Most reviews that disseminated a supportive evaluation of the results of RCTs in the context of secondary prevention cited only data that supported this position.…”
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695
Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19: a systematic review and meta-analysis
Published 2025-01-01“…The global online databases were used to identify relevant studies published between December 2019 and July 2024. Data analysis was performed using STATA Ver. 17 software, and standard errors of prevalence were calculated using the binomial distribution formula. …”
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Surgical Outcomes and Sociodemographic Disparities Across All Races: An ACS-NSQIP and NHIS Multi-Institutional Analysis of Over 7.5 Million Patients
Published 2024-09-01“…In a separate, independent analysis of the 2019 to 2020 National Health Interview Survey (NHIS) database, we examined sociodemographic racial/ethnic normative data. …”
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Association between triglyceride-glucose index and all-cause mortality in critically ill patients with acute myocardial infarction: analysis of the MIMIC-IV database
Published 2025-01-01“…Our research analyzed the correlation between the TyG index and the risk of mortality in patients with AMI, in order to evaluate the influence of the TyG index on the prognosis of this population.Methods1205 ICU patients with AMI were analyzed in this retrospective cohort analysis, and the necessary data were obtained from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. …”
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