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2981
Progress and insights from worldwide deep coalbed methane exploration and development
Published 2025-01-01“…Experiences from CBM exploration and development shows that breakthroughs in understanding enrichment patterns, advancements in engineering technologies, integrated management models, and industry- supportive policies are important factors for the rapid development of the CBM industry. …”
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2982
Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity
Published 2025-02-01“…In order to enable internalization into tumor cells, supramolecular engineering techniques were employed through terminal modification involving sulfydryl and monovalent gold ion (Au(I)), both facilitating self-assembly of modified PEPPDL1 into supramolecular nanospheres termed CTAC-PDL1 driven by aurophilic interaction. …”
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2983
High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis
Published 2025-02-01“…In order to deeply investigate this scientific issue, we constructed a high-altitude hypoxic TBI model at different altitudes and used animal behavioral assessments (Modified neurological severity score, rotarod test, elevated plus maze test) as well as histopathological analyses (brain gross specimens, brain water content, Evans blue content, hypoxia inducible factor-1α, Hematoxylin-Eosin staining and ROS detection) to reveal its underlying principles and characteristics. …”
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2984
Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides
Published 2025-02-01“…N-(3,5-Dimethylphenyl)-2-hydroxynaphthalene-1-carboxamide (13) showed only anti¬sta¬phylococcal activity (minimum inhibitory concentration (MIC) = 54.9 µM); 2-hydroxy-N-[2-methyl-5-(tri¬fluoro¬methyl)phenyl]naphthalene-1-carboxamide (22) and 2-hydroxy-N-[4-nitro-3-(trifluoromethyl)phe¬nyl]na¬phtha¬lene-1-carboxamide (27) were active across the entire spectrum of tested bacteria/mycobacteria, both against the sensitive set and against resistant isolates (MICs range 0.3 to 92.6 µM). …”
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2985
Historical and projected forest cover changes in the Mount Kenya Ecosystem: Implications for sustainable forest management
Published 2025-06-01“…Land Use Land Cover (LULC) maps for 2000, 2014, and 2023 were classified using Random Forest (RF) in Google Earth Engine (GEE). Explanatory factors of LULC change (slope, aspect, population density, proximity to rivers, roads, and towns) were used to project LULC for 2035 using Cellular Automata and Markov Chain Analysis (CA-MCA).Six LULC types (open forest, closed forest, cropland, bareland, built-up, shrubland and grassland) were successfully classified with accuracies exceeding 82.5% and Kappa coefficients above 0.77. …”
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2986
Chemotaxonomic studies on <i>Schwenckia americana</i> LINN
Published 2016-05-01“…The leaves are simple, entire, elliptic to ovate in shape, smooth, variable, petiolate and larger at the lower region of stem and narrowing to smaller almost sessile and oblanceolate towards the apical regions which are alternately arranged and acrescently structured from the top to the base up to 3.7 ± 1.5cm long and 2.4±0.6cm wide. …”
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2987
Information Communication Technology and Performance of Commercial Banks in Uganda: A Case Study of Equity Bank In Kabale Municipality.
Published 2024“…The study also recommended that the ICT infrastructure of the bank in the form of cables, switches, and routers should be improved to the desired standards to enable the clients to be provided with adequate and timely services, the bank officers especially the older employees should be trained on the use of technological gadgets to remove technological phobia among them to equip the entire bank staff with the required skills to to perform their duties effectively, the bank officers should be trained on the process of ensuring digital preservation to equip them with knowledge of digital preservation, there should be better vertical communication to enable the provision of effective feedback that leads to better organizations performance and there should be strong coordination across functions of the bank to achieve the desired and intended goals for success.…”
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2988
Procurement Planning and Service Delivery in Local Governments in Uganda: A Case Study of Kabale District Local Government.
Published 2024“…The relationship between procurement planning and service delivery showed that procurement planning initiates the entire procurement process in local government and facilitates efficient and effective service delivery in the public sector. …”
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2989
Modeling Concrete Compressive Strength Variation with Age Using Origin Pro Software.
Published 2024“…The developed model can be utilized in construction planning, quality control, and material research. …”
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2990
Recommender Systems for Unified Modeling Language and Vice Versa—A Systematic Literature Review
Published 2025-01-01“…Recommender systems (RSs) are fundamental tools that address data redundancy and serve as intelligent supplements for tasks such as data retrieval and refinement by analyzing user behavior. Nowadays, RSs are utilized in various domains, ranging from filtering web news based on user preferences to recommending movies, music, books, and articles in e-commerce. …”
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2991
THE ACCEPTANCE OF AN EDUCATIONAL INTEGRATED DEVELOPMENT ENVIRONMENT TO LEARN PROGRAMMING FUNDAMENTALS
Published 2023-02-01“… Programming is an important course for any IT or engineering-related course. However, previous research shows that students face difficulties in learning programming due to its abstract concepts. …”
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2992
Metabolic redundancy and specialisation of novel sulfide-oxidizing Sulfurimonas and Sulfurovum along the brine-seawater interface of the Kebrit Deep
Published 2025-02-01“…In addition to the osmoprotectant pathways commonly observed in Campylobacterota, such as the synthesis and uptake of proline and glutamate, the two Kebrit Deep Sulfurovum species exhibit genomic signatures for ectoine synthesis, further aiding their adaptation to high salinity. …”
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2993
Simulation and experimental study on olive drop injury
Published 2025-03-01“…Second, a three-dimensional model of oil olives was established by reverse engineering, and collision simulations with different heights, multiple collision angles, and different contact materials were carried out in finite elements to obtain the damage volume, energy, and damage susceptibility. …”
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2994
CytoSorb hemoadsorption of apixaban during cardio-pulmonary bypass for heart transplantation
Published 2025-02-01“…Hemoadsorption by a CytoSorb cartridge was performed during the entire CPB duration. Anti-Factor Xa Activity (AFXaA) levels were taken before, during and after surgery in order to monitor anticoagulation. …”
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2995
Scaling up computational thinking skills in computer-assisted language learning (CTsCALL) and its fitness with language learners’ intentions to use virtual exchange: A bi-symmetric...
Published 2025-03-01“…In this regard, pedagogical experts in Science, Technology, Engineering, and Mathematics (STEM) have developed programming and robotics based on Computational Thinking skills (CTs), which have been regarded as the core of 21st-century skills. …”
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2996
Microstructural analysis and preliminary wear assessment of wire arc additive manufactured AA 5083 aluminum alloy for lightweight structures
Published 2025-01-01“…The study demonstrates that WAAM-produced AA 5083 aluminum alloy, with an anisotropy below 10 %, is suitable for real-time lightweight structures, offering effective performance in engineering applications such as aerospace and automotive industries. …”
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2997
Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [13C]bicarbonate metabolism in mice
Published 2025-02-01“…In studies of the mouse brain using hyperpolarized [1-13C]pyruvate, there are few reports that the signal of [13C]bicarbonate, a product of oxidative phosphorylation metabolized from [1-13C]pyruvate, was detected using MR spectroscopic imaging (MRSI) that allows spatial mapping of metabolism, although there have been reports of [13C]bicarbonate signals being detected by pulse-acquire sequences in the entire brain. In the present study, we compared hyperpolarized [1-13C]pyruvate metabolism between the brains of awake and isoflurane-anesthetized mice using a custom-made awake mouse restraint device with MRSI. …”
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2998
The Hidden Economic Consequences of Migraine to the UK Government: Burden-of-Disease Analysis Using a Fiscal Framework
Published 2023-10-01“…Annually, migraine was estimated to represent £12.20 billion to the public economy, approximately £130.63 per migraine episode. …”
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2999
Predicting nighttime black ice using atmospheric data for efficient winter road maintenance patrols
Published 2025-01-01“…However, patrolling the entire road network on a daily basis requires substantial human and equipment resources. …”
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3000
Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats
Published 2025-02-01“…Histomorphometric evaluations were performed on the kidney sections stained with hematoxylin and eosin (H&E). Results: HPLC identified the presence of vitexin, isovitexin, quercetin, and kaempferol in F. deltoidea methanolic leaves extract. …”
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