The potential of epigenetic methods to provide evidence of torture by Paula Suárez-López

“…Given that torture is an extreme form of trauma, this article argues that torture may also be associated with epigenetic changes. Discussion: Epigenetic methods offer a new tool that might be useful for the medico-legal documentation of cases of torture. …”
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Novel Epigenetic Techniques Provided by the CRISPR/Cas9 System by Nina Xie, Yafang Zhou, Qiying Sun, Beisha Tang

“…In recent years, the emergence of CRISPR/Cas9 technology has provided us with new routes to the epigenetic field. …”
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DNA methylation provides new insights into the epigenetic regulation of Vibrio parahaemolyticus infection in Portunus trituberculatus by Dongfang Sun, Xianfa Zhou, Shaoting Jia, Ping Liu, Jianjian Lv

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Genome assembly of the maize B chromosome provides insight into its epigenetic characteristics and effects on the host genome by Qian Liu, Yang Liu, Congyang Yi, Zhi Gao, Zeyan Zhang, Congle Zhu, James A. Birchler, Fangpu Han

“…Using CENH3 ChIP-seq data, we accurately determined the position of the B chromosome centromere, which features a unique monomer-composed satellite array distinct from that found on the chromosome arms. Our research provides detailed genetic and epigenetic maps of the B chromosome, shedding light on its molecular landscape, including DNA sequence composition, DNA methylation patterns, histone modifications, and R-loop distributions across various chromatin regions. …”
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The Role of Epigenetics in Cardiovascular Disease: Providing Insights into Disease Mechanisms and Evaluating Therapeutic Potential for Future Treatment Strategies by Omar Elsaka

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Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis. by Paul E Young, Stephen Kum Jew, Michael E Buckland, Roger Pamphlett, Catherine M Suter

“…In conclusion, widespread changes in methylation patterns were found in ALS-affected co-twins, consistent with an epigenetic contribution to disease. These DNA methylation findings could be used to develop blood-based ALS biomarkers, gain insights into disease pathogenesis, and provide a reference for future large-scale ALS epigenetic studies.…”
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Genome-wide DNA methylation regulation analysis provides novel insights on post-radiation breast cancer by Jianghuai Ji, Dongguo Li, Xiaoxiao Zhao, Yajuan Wang, Binbing Wang

“…Finally, we further used independent samples to verify CD248 expression and established a simple epigenetic regulatory model. In summary, this study provides novel insights for understanding the regulation of target genes mediated by DNA methylation and developing potential biomarkers for radiation-associated secondary diseases in BC.…”
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Exploring the role of epigenetic regulation in cancer prognosis with epigenetic score by Ruiguang Zhang, Shimin Jin, Qi Xu, Rongxiao Dai

“…Additionally, we created a nomogram that integrates the epigenetic score and clinical features, providing a more comprehensive tool for tumor patients prognosis assessment.ResultsWe calculated the epigenetic score based on the expression levels of epigenetic-related genes. …”
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Mutations in Epigenetic Modifiers in Myeloid Malignancies and the Prospect of Novel Epigenetic-Targeted Therapy by Amir T. Fathi, Omar Abdel-Wahab

“…In the recent years, the discovery of a series of mutations in patients with myeloid malignancies has provided insight into the pathogenesis of myelodysplastic syndromes (MDSs), myeloproliferative neoplasms (MPNs), and acute myeloid leukemia (AML). …”
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Epigenetics in Skin Homeostasis and Ageing by Iasonas Dermitzakis, Stella Aikaterini Kyriakoudi, Sofia Chatzianagnosti, Despoina Chatzi, Efstratios Vakirlis, Soultana Meditskou, Maria Eleni Manthou, Paschalis Theotokis

“…The present review endeavours to provide a comprehensive exploration and elucidation of the role of epigenetic mechanisms in regulating skin homeostasis and ageing. …”
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Epigenetic regulation of cancer stemness by Claudia Galassi, Gwenola Manic, Manel Esteller, Lorenzo Galluzzi, Ilio Vitale

“…Here, we provide an in-depth discussion of the impact of epigenetic alterations on cancer stemness, i.e., the ability of a small population of poorly differentiated malignant cells to (1) self-renew while generating a more differentiated progeny, and (2) exhibit superior tumor initiating/repopulating potential along with exceptional plasticity and improved resistance to environmental and therapy-elicited stress. …”
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Epigenetic age and fertility timeline: testing an epigenetic clock to forecast in vitro fertilization success rate by Davide Marinello, Marco Reschini, Giorgia Di Stefano, Giorgia Carullo, Maíra Casalechi, Letizia Tarantini, Benedetta Albetti, Valentina Bollati, Paola Viganò, Edgardo Somigliana, Letizia Li Piani

“…Abstract Background In the field of in vitro fertilization (IVF), the search for reliable success predictors is ongoing, with novel biomarkers gaining increasing attention. Epigenetic clocks, mathematical models based on DNA methylation (DNAm) patterns, have revolutionized aging research by providing insights into biological aging. …”
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Epigenetic Regulation of B Cell Memory Formation: A Poised Model for B Cell Epigenetic Reprograming by Carlos Valverde-Hernandez

“…Recent discoveries in epigenetics and immune memory have elucidated the essential role of epigenetic regulators in establishing the memory B cell (MBC) fate. …”
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The epigenetic hallmarks of immune cells in cancer by Yu Ji, Chu Xiao, Tao Fan, Ziqin Deng, Di Wang, Wenpeng Cai, Jia Li, Tianle Liao, Chunxiang Li, Jie He

“…This review provides the epigenetic foundations of cancer immunity and proposes the future direction of combination therapies.…”
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Circadian rhythm, epigenetics and disease interaction by Meyrem Osum, Rasime Kalkan

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Clinical epigenetics: recent advances and opportunities by Jim Smith, Aniruddha Chatterjee, Euan J. Rodger

“…Abstract Clinical epigenetics as a field has experienced rapid advancement over recent decades. …”
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Glucocorticoid receptor epigenetic activity in the heart by Olukunle Akinborewa, Mattia Quattrocelli

“…In this review, we provide an overview of the glucocorticoid receptor’s role in cardiac physiology, detailing its genomic and non-genomic pathways, interactions with epigenetic and circadian regulatory mechanisms, and implications for cardiovascular disease. …”
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Epigenetics in Plant Response to Climate Change by Wei Zhou, Min Wang, Lishan Wang, Yinghui Liu, Zaimin Tian, Linan Xie, Yu Wang

“…In this review, we synthesize current knowledge on the epigenetic mechanisms underlying plant responses to environmental changes and examine the dynamic interplay between epigenetic regulation and environmental stimuli, aiming to provide insights into enhancing the tolerance of plants to environmental stress factors.…”
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Impacts of epigenetic reprogramming on innate immunity by Jie Fu, Yizhen Wang

“…In summary, this review aims to uncover the molecular mechanisms underlying the development, differentiation, and activation of IICs from an epigenetic perspective, providing theoretical foundations for scientific and medical researchers pursuing disease treatments.…”
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The Role for Epigenetic Modifications in Pain and Analgesia Response by Sherrie Lessans, Susan G. Dorsey

“…Pathological alterations to chromatin shape the ability of the cell to respond to physiologic and environmental cues leading to disease and reduced treatment effectiveness. This review provides an overview of critical epigenetic processes shaping pathology and pain, highlights current research support for the role of epigenomic modification in the development of chronic pain, and summarizes the therapeutic potential to alter epigenetic processes to improve health outcomes.…”
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