Clinical characteristics of and growth hormone treatment effects on short stature with type 1 insulin-like growth factor receptor (IGF1R) gene alteration by Yuki Kawashima-Sonoyama, Keisuke Wada, Kei Yamamoto, Masanobu Fujimoto, Noriyuki Namba, Takeshi Taketani

“…Four cases were caused by a deletion of chromosome 15q26.3, and eight were caused by heterozygous pathogenic variants in the IGF1R gene. …”
Get full text

Preliminary ultrasonography study of the pancreas in the dromedary camel (Camelus dromedarius) by El Hassania Lakhel, Khalid El Allali, Mohamed Rachid Achaâban, Rahma Azrib

“…This study aimed to define the ultrasonographic appearance, reference values, location, and acoustic window for evaluating the pancreas in healthy camels.MethodsEight adult and 14 young Moroccan camels were investigated by ultrasonography using a micro-convex probe with SIUI CTS-900 V and Samsung MH70A Doppler ultrasound scanners at 3.5 MHz.ResultsThe body of the pancreas was scanned just below the right kidney, behind the 12th rib; an ultrasonographic pattern of pancreatic parenchyma appeared as a hyperechoic elongated band, including the portal vein, with a Doppler flow response. …”
Get full text

Observed upper-ocean structure and seasonal production in the southern Kerguelen Plateau region, 1994-2021 by Man Liang, Annie Foppert, Annie Foppert, Karen J. Westwood, Karen J. Westwood, Sophie Bestley, Sophie Bestley

“…We collate ship-based hydrographic data on the vertical structure of the upper water column near 80°E from eight voyages spanning 1994 to 2021, from 58°S towards the Antarctic continent. …”
Get full text

A Speed-Invariant Template-Based Approach for Estimating Running Temporal Parameters Using Inertial Sensors by Rachele Rossanigo, Marco Caruso, Elena Dipalma, Cristine Agresta, Lucia Ventura, Franca Deriu, Andrea Manca, Taian M. Vieira, Valentina Camomilla, Andrea Cereatti

“…This study evaluated the speed-dependance of eight relevant foot-mounted inertial-based methods from previous research and proposed a novel method that could be robust to speed changes. …”
Get full text

The Association between Polymorphisms of Vitamin D Metabolic-Related Genes and Vitamin D3 Supplementation in Type 2 Diabetic Patients by Zhiyong Hu, ShaSha Tao, Huaqing Liu, Guotao Pan, Bingyan Li, Zengli Zhang

“…Multiplex TaqMan genotyping was used to determine the distribution of eight candidate SNPs in genes of DHCR7, CYP2R1, CYP27B1, CYP24A1, and VDR, which are key genes in the vitamin D metabolic pathway, in diabetic patients. …”
Get full text

Using Statistical Analysis to Assess Urban Groundwater in Beni Mellal City (Morocco) by Mohamed El Baghdadi, Radouane Medah, Amal Jouider

“…PCA of all dataset highlights eight factors with eigenvalues higher than 1 that explained about 80.34% of the total variance. …”
Get full text

Complex Study of Settlements Dating from the Paleolithic to Medieval Period in the Ural Mountains on the Border of Europe and Asia by Valentina Prikhodko, Nikita Savelev, Vyacheslav Kotov, Sergey Nikolaev, Evgeny Ruslanov, Mikhail Rumyantsev, Elena Manakhova

“…Soil, geochemical, microbiological, and archeological studies were conducted at eight settlements dating from the Paleolithic to Late Medieval and Modern Ages near the southern Trans-Urals Mountains, Russia. …”
Get full text

Modelling the health, financial protection and equity impacts of upscaling the ACT NOW early intervention breast cancer pilot program in the Philippines: an extended cost-effective... by Blake Angell, Stephen Jan, Mark Woodward, Sanne Peters, Merel Kimman, Alexander Chye, Nirmala Bhoo Pathy, Herdee Gloriane C Luna, Soledad B Lim, Helen Monaghan, Corazon A Ngelangel

“…Per 100 000 women, 57 deaths and eight financial catastrophes were saved. Cost-effectiveness did not vary significantly by income, but higher income groups incurred greater costs and lower DALYs. …”
Get full text

Une statue de togatus découverte dans l’agglomération antique de Briord (Ain) by Thomas Le Saint Quinio, Maria-Pia Darblade-Audoin

“…The figure appears to have a pronounced swaying of the hips and there is some corresponding twisting of the pleats below the left hand. This toga, without umbo, retains, in its overall shape, certain features of the Roman toga dating to the 1st c. …”
Get full text

Association of sodium–glucose cotransporter-2 inhibitors with mortality across the spectrum of myocardial infarction: a systematic review and meta-analysis by Michele Maremmani, Ramin Ebrahimi, Marco Centola, Felice Achilli, Valentina Capone, Eduardo Bossone, Christian Templin, Davide Di Vece

“…We pooled hazard ratios (HRs) to estimate the intervention's effect on the overall population and stratified studies into early (SGLT2 inhibitors administered within eight weeks post-MI) and delayed treatment trials. …”
Get full text

Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in pat... by Christy Ralph, Sumati Gupta, Matthew Zibelman, Brendan D Curti, Kevin J Harrington, Steven J O'Day, Andrew G Hill, David C Campbell, Gavin M Wright, David E Gerber, Jonathan E Rosenberg, Jaime R Merchan, Charles M Rudin, Hardev S Pandha, Wallace L Akerley, Daphne Day, Timothy D Clay, Ross R Jennens, Yixin Ren, Emmett V Schmidt, Lisa Guttman

“…Patients received intravenous V937 on days 1, 3, and 5 (also on day 8 in part B) of the first 21-day cycle and on day 1 of subsequent cycles for eight cycles. Three ascending dose-escalation cohorts were studied. …”
Get full text

Efficacy and Safety of High-dose versus Standard-dose Prazosin in Paediatric Scorpion Envenomation: A Single-blinded Randomised Controlled Study by Apoorva Gayatri Abbadi, Hidaytullah R Bijapure, Chandrika R Doddihal, Bhavana B Lakhkar, Y Rohith, VJ Prakash, Kumar BM Prasanna, Mallanagouda Patil

“…The standard protocol (Group A) had 26, Group B had 29 and Group C had 31 children. Forty-eight (56%) of the children were over five years old (12, 21 and 15 were in Groups A, B and C, respectively). …”
Get full text

Villa d’époque romaine et habitat médiéval à Mont-Saint-Jean (Sarthe) : bilan des recherches 2008-2020 by Florian Sarreste, Paul-André Besombes, Phaedra Bouvet, Chloé Genies, Étienne Jaffrot, Florian Jedrusiak, Thomas Jubeau, Anthony Ledauphin, Annaïg Le Martret, Christophe Loiseau, Hugo Meunier, Aurore Noël, Sandrine Paradis-Grenouillet, Boris Robin

“…However, the maintenance of earthen and wooden buildings for nearly eight centuries suggests that, if there was a hiatus, it was short-lived.The medieval settlement appears to have declined before the year 1000. …”
Get full text