Association of socioeconomic status with diabetic microvascular complications: a UK Biobank prospective cohort study by Yikeng Huang, Zhi Zheng, Haibing Chen, Chufeng Gu

“…Conclusions Low SES increases the risk of diabetic microvascular complications, emphasizing the need for equitable medical resource allocation to reduce diabetes-related inequity.…”
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Ice-proximal sea ice reconstruction in the Powell Basin, Antarctica, since the Last Interglacial by W. W. Khoo, J. Müller, J. Müller, J. Müller, O. Esper, W. Xiao, C. Stepanek, P. Gierz, G. Lohmann, G. Lohmann, G. Lohmann, W. Geibert, J. Hefter, G. Mollenhauer, G. Mollenhauer, G. Mollenhauer

“…Finally, despite similar findings between the proxy and model data, notable differences persist between both interglacials – emphasizing the necessity for different Antarctic ice sheet configurations to be employed and more robust paleoclimate data to enhance climate model performance close to the Antarctic continental margin.…”
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First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka by Jagadish B. Hiremath, M. Swathi, R. Ramamoorthy, M. Shijili, Damini Sharma, Divakar Hemadri, H. B. Chethankumar, K. P. Suresh, Sharanagouda S. Patil, Shivasharanappa Nayakvadi, S. P. Satheesha, B. R. Shome, Baldev Raj Gulati

“…Conclusion This study reports the first clinical outbreak of PED in India and identifies the circulating genotype of PEDV. The study emphasizes the need for large-scale surveillance studies to understand the disease’s status. …”
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Postoperative radiotherapy improves survival in completely resected non-small cell lung cancer with pathologic N2 stage IIIA and positive lymph node count greater than one: a SEER-... by Diyang Zhu, Yuanyuan Xiao, Yuanyuan Xiao, Shancheng He, Shancheng He, Baochang Xie, Baochang Xie, Wenqi Zhao, Wenqi Zhao, Yuhui Xu

“…These findings suggest that PORT may offer improved outcomes in patients with extensive lymph node involvement, emphasizing the need for further prospective studies to validate and expand upon these observations.…”
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Assessment of Air Pollution and Lagged Meteorological Effects in an Urban Residential Area of Kenitra City, Morocco by Mustapha Zghaid, Abdelfettah Benchrif, Mounia Tahri, Amine Arfaoui, Malika Elouardi, Mohamed Derdaki, Ali Quyou, Moulay Laarbi Ouahidi

“…SO₂ concentrations were shaped by both immediate and lagged meteorological effects, with wind direction playing a key role in pollutant transport. These findings emphasize the importance of considering both immediate and lagged meteorological effects, as well as seasonal and diurnal variations, in developing air quality management strategies.…”
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Factors influencing the quality of life and mental health of Brazilian Federal Education Network Employees: An epidemiological cross-sectional study by Isabela Fernanda Rodrigues de Oliveira, Nicolli Godoi Pereira, Luís Fernando Monteiro, Leonardo Mateus Teixeira de Rezende, Claudio Andre Barbosa de Lira, Manuel Monfort-Pañego, Woska Pires da Costa, Priscilla Rayanne E. Silva Noll, Matias Noll

“…The current findings emphasize the need for intervention measures for Brazilian education employees to promote physical activity, healthy food consumption, reduced screen time, and awareness of the harm of risky behaviors, such as tobacco and alcohol, to enhance their QoL and mental health.…”
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Efficacy of Chinese Medicine on Postoperative Rehabilitation of Non-small Cell Lung Cancer (NSCLC), a Randomized Controlled Study by Yifeng Gu MD, Yichao Wang MD, Huiling Zhou MD, Ao Qi PhD, Guanjin Wu MM, Jiaqi Li MMed, Congmeng Zhang MMed, Yong Yang MD, Jialin Yao MD, Wenxiao Yang PhD, Lingzi Su MMed, Yi Liu MMed, Xueqi Tian MMed, Jiajun Song MMed, Yabin Gong MD, Xiong Qin MD, Lijing Jiao PhD, Ling Xu PhD

“…Background: With an increasing number of non-small cell lung cancer (NSCLC) patients being offered surgical treatment, postoperative rehabilitation is also being increasingly emphasized. Traditional Chinese medicine (TCM) holds promise for enhancing postoperative recovery, with treatment methods still in refinement. …”
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Exploring Dance as a Therapeutic Approach for Parkinson Disease Through the Social Robotics for Active and Healthy Ageing (SI-Robotics): Results From a Technical Feasibility Study by Roberta Bevilacqua, Elvira Maranesi, Marco Benadduci, Gabriella Cortellessa, Alessandro Umbrico, Francesca Fracasso, Giovanni Melone, Arianna Margaritini, Angela La Forgia, Pierpaolo Di Bitonto, Ada Potenza, Laura Fiorini, Carlo La Viola, Filippo Cavallo, Alessandro Leone, Andrea Caroppo, Gabriele Rescio, Mauro Marzorati, Amedeo Cesta, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Lorena Rossi

“…Several findings in the literature emphasize the necessity for deeper exploration into the synergistic impacts of dance therapy and exergaming for PD management. …”
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Quantification of regional net CO₂ flux errors in the Orbiting Carbon Observatory-2 (OCO-2) v10 model intercomparison project (MIP) ensemble using airborne measurements by J. Yun, J. Liu, J. Liu, B. Byrne, B. Weir, B. Weir, L. E. Ott, K. McKain, B. C. Baier, L. V. Gatti, S. C. Biraud

“…This suggests the presence of systematic biases in the inversion estimates associated with errors in the prescribed fossil fuel emissions common to all models. Our study emphasizes the value of airborne measurements for quantifying regional errors in ensemble net CO<span class="inline-formula">₂</span> flux estimates.…”
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Lyophilized human platelet lysate: manufacturing, quality control, and application by Kerstin Wendland, Kerstin Wendland, Lea Koblin, Lea Koblin, Dirk Stobbe, Anna Dahms, Anna Dahms, Debora Singer, Debora Singer, Sander Bekeschus, Sander Bekeschus, Jan Wesche, Janosch Schoon, Konstanze Aurich

“…The comparison of L-HPL with HPL did not reveal any relevant differences regarding quality control parameters of routine testing, growth factor concentrations and hMSC functionality, demonstrating the suitability of L-HPL as a cell culture supplement. These results emphasize the potential of L-HPL as a sustainable and ethical alternative to animal-derived serum products in biomedical research and drug development.…”
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Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study by Yan-Hua Zheng, Kun Xie, Hong-Yuan Shen, Zhuo Wan, Shan Gao, Wen-Rui Sun, Guang-Xun Gao, Li Liu, Juan Feng

“…The main therapeutic regimens were CHOP or CHOPE, DA-EPOCH, DHAP and ESHAP. A complete response (CR) was achieved in only 3 patients, while a partial response was achieved in 10 patients. …”
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Association between joint exposure to ambient air pollutants and carotid plaque: The mediating role of cardiometabolic risk factors by Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao

“…LDL-C and MAP suggest partial mediating effects of joint air pollution on carotid plaques. Our results emphasize the need to thoroughly evaluate various air pollutants concerning carotid plaque.…”
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Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion by Michelle Pfaffenlehner, Max Behrens, Daniela Zöller, Kathrin Ungethüm, Kai Günther, Viktoria Rücker, Jens-Peter Reese, Peter Heuschmann, Miriam Kesselmeier, Flavia Remo, André Scherag, Harald Binder, Nadine Binder, for the EVA4MII project

“…We highlighted key challenges that have high potential to impact analysis results, emphasizing the need for thorough consideration and discussion for meaningful inferences.…”
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Country economic status is strongly associated with burn survival - validation of the (modified) ABSI by Julia Elrod, Christoph Mohr, Ludvik Branski, Joshua M. Peterson, Fionna M. Wood, Dale W. Edgar, Pius Agbenorku, Shobha Chamania, Anant Sharma, Flavio N. Novaes, Jean Bosco Katabogama, Michael Boettcher, Konrad Reinshagen, Ingo Koenigs

“…These findings underscore the need for adaptive models that take into account socioeconomic variables, potentially guiding health policy adjustments and emphasizing the necessity of resource allocation and training in lower HDI countries. …”
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Multidimensional 1-Year Outcomes After Intensive Care Admission for Multisystem Inflammatory Syndrome in Children by Thomas C. Seijbel, BSc, Levi Hoste, MD, Corinne M. P. Buysse, MD, PhD, Karolijn Dulfer, PhD, Filomeen Haerynck, MD, PhD, Matthijs de Hoog, MD, PhD, Naomi Ketharanathan, MD, PhD

“…However, many still reported a variety of multidimensional sequelae at 1-year follow-up impacting daily life. This emphasizes the importance of continued investigative efforts and multidisciplinary follow-up programs to better understand pathophysiology and contributing factors to the MIS-C disease trajectory and initiate patient-specific interventions to improve outcome and social participation.…”
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Dietary supplementation of composite feed additive reduces enteric methane production and enhances feed efficiency, milk production and immunity in Murrah buffalo (Bubalus bubalis) by Avijit Dey, Shyam S. Paul, Satbir S. Dahiya, Ashok K. Balhara, Jerome Andonissamy, Balbir S. Punia, Yendrembam M. Chanu

“…The results revealed increased digestibility of nutrients, especially crude fiber, with decreased (p<0.05) methane concentration in the exhaled air of lactating buffaloes. The health status regarding cell-mediated and humoral immune response was also enhanced (p<0.05) in supplemented buffaloes. …”
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KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitors by Linyan Tian, Chengming Liu, Sufei Zheng, Huiyang Shi, Fang Wei, Wenxin Jiang, Yucheng Dong, Haiyan Xu, Enzhi Yin, Nan Sun, Jie He, Yan Wang

“…The findings highlight the urgent need for alternative therapeutic approaches in KEAP1-mutant patients and emphasize the role of molecular profiling in tailored treatment strategies.…”
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Genetic profiling of extended-spectrum β-Lactamase and carbapenemase-producing Escherichia coli O157:H7 from clinical samples among diarrheal patients in Shashemene, Ethiopia by Shimelis Teshome Ayalneh, Biruk Yeshitela Beshah, Yeonji Jeon, Ashenafi Alemu Wami, Seifegebriel Teshome, Solomon Gebreselassie, Se Eun Park, Mekonnen Teferi, Woldaregay Erku Abegaz

“…Key factors contributing to this resistance, such as urban environments, children under the age of five, and domestic animal ownership, have been emphasized. Additionally, this research underscores the urgent need for enhanced surveillance and targeted interventions to address this pressing public health concern.…”
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