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Cathepsin-K Targeted by Sanggenol L Induces Lethal Autophagy through ROS-Dependent AMPK/mTOR Signaling in Gastric Cancer
Published 2025-06-01Subjects: “…abbreviations: cTSK, Cathepsin K…”
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Quantitative analysis of nighttime effects of radiation belt energetic electron precipitation on the D-region ionosphere during lower solar activity periods
Published 2025-08-01“…<p>Energetic electron precipitation (EEP) from the Earth's radiation belts can ionize neutral molecules in the D-region ionosphere (60–90 km altitude), significantly influencing the conductivity and chemical species therein. …”
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Tutorial on running median subtraction filter with application to searches for exotic field transients in multi-messenger astronomy
Published 2025-05-01“…With a suitable choice of running window size, RMSF effectively filters out baseline variations without compromising the integrity of transients. …”
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LesePfad (Lesepakte mit formativem Assessment digital)
Published 2025-03-01“…Dabei wurden einerseits Erkenntnisse aus der Leseforschung und andererseits aus der Forschung zu digitalen Lerntools in Hinblick auf Usability berücksichtigt. …”
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An Adversarial Attack on ML-Based IoT Malware Detection Using Binary Diversification Techniques
Published 2024-01-01“…To this end, we stage a black-box attack on IoT malware detection systems, specifically targeting structure-based detectors, which are predominant due to their ability to detect malware across diverse CPU architectures in IoT environments. …”
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Zeitgemässe integrative Förderung hochbegabter Schülerinnen und Schüler der Primarstufe
Published 2025-07-01“…Diese Darstellung erschien von wesentlicher Bedeutung, um den aktiven und individuellen Förderbedarf zu identifizieren. …”
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Therapeutic application of nano-encapsulated pomegranate peel extract attenuated DSS-induced colitis: Antioxidant and anti-inflammatory role and reduction of exaggerated response o...
Published 2025-01-01“…The colitic group showed a significant increase (P < 0.05) in C-reactive protein (CRP) and myeloperoxidase (MPO) and nitric oxide (NO) (35.60, 163.30 and 280 nmol/g tissue respectively) and higher expression (P < 0.05) IL-17, TNF-α, and IL-1β (increased up to 2.99, 4.36 and 4.90 respectively unlike PPE-NPsIII that recorded reduced levels of CRP, MPO and NO (8,96, 78.30 and 123 nmol/g tissue respectively) and much lower (P < 0.05) levels of IL-17, TNF-α, and IL-1β expression (decreased to 1.23, 1.69 and 1.64, respectively). …”
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Ambient temperature influenced co-expression network of major developmental, circadian, and photoreceptor genes in bread wheat
Published 2025-07-01“…For this purpose, we chose three, well characterised winter bread wheat varieties with different genetic backgrounds and developmental patterns, in which we studied the daily expression of main developmental (VRN1, VRN2, VRN3, PPD1), circadian (CCA1, PRR95, TOC1, LUX, ELF3, GI, CO1) and photoreceptor (PHYA, PHYB, PHYC, CRY1, CRY2) genes using generic primers and determined their possible relationship under three environments (18 °C vernalized/unvernalized and 25 °C vernalized in the phytotron). …”
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