DEVELOPMENT OF METHODS OF SIMULATION OF THE INTERACTION OF BIOLOGICALLY ACTIVE SUBSTANCES WITH THE ACTIVE CENTER OF ANGIOTENSIN-CONVERTING ENZYME by A. A. Glushko, A. S. Chiriapkin, V. S. Chiriapkin, A. M. Murtuzalieva, Yu. A. Polkovnikova

“…The principle of action of ACE inhibitors is based on blocking the conversion of angiotensin I into angiotensin II, which mediates vasodilation.The aim of the work is a selection of methods of lisinopril interaction with the active center of angiotensin-converting enzyme by molecular dynamics methods.Materials and methods. …”
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New Structural Seismic Isolation for Nuclear Containment Structures by Azer A. Kasimzade, Obaidullah Abrar, Mehmet Kuruoglu, Gencay Atmaca

“…This study has investigated the performance of the SSIS for the nuclear containment (SSIS-NC) structure. The finite element model of SISS-NC structure has been developed, and nonlinear dynamic analysis of the model has been conducted under the strong and long-period ground motions. …”
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A novel in-situ rapid crack detection approach for reinforced concrete structures using improved active contour contraction image segmentation method by Boxu Lin, Qing Chun, Zhengdong Mi, Yu Yuan

“…This paper proposes a novel mathematics-based crack detection method. It features: (1) integrated image preprocessing (denoising/super-resolution) to enhance image quality, and (2) a dynamic localized-region contour contraction technique for efficient, accurate, rapid multi-crack segmentation. …”
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School-Based Health Centers Addressing Health Equity for LGBTQ + Patients (SBHCs HELP): protocol for a stepped-wedge trial to implement innovations promoting structural competency... by Cathleen E. Willging, Daniel Shattuck, Marisa Sklar, Rachel A. Sebastian, Robert L. Stout, Mary M. Ramos

“…Methods We will conduct mixed-method readiness assessments to identify inner- and outer-context determinants affecting the implementation of structurally competent changes in SBHCs; employ a stepped-wedge trial to examine how the DAP-enabled implementation impacts adoption and changes in SBHC, student (patient), and implementation outcomes; and investigate inner- and outer-context determinants, bridging factors, and associated mediators and moderators influencing implementation processes and outcomes related to guideline adoption and SGD student care (e.g., reduced barriers, greater satisfaction and engagement). …”
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Structure-Based Design and In-Silico Evaluation of Computationally Proposed Curcumin Derivatives as Potential Inhibitors of the Coronaviral PLpro Enzymes by Hakan Alici

“…Further validation through MD simulations and MM/PBSA calculations confirmed the structural stability and robust interactions of the most promising derivatives within the SARS-CoV PLpro active site. …”
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Patient-specific fluid–structure simulations of anomalous aortic origin of right coronary arteriesCentral MessagePerspective by Michael X. Jiang, MD, MEng, Muhammad O. Khan, PhD, Joanna Ghobrial, MD, Ian S. Rogers, MD, Gosta B. Pettersson, MD, PhD, Eugene H. Blackstone, MD, Alison L. Marsden, PhD

“…Meanwhile, advances in fluid–structure interaction (FSI) modeling can simulate the pulsatile hemodynamics and tissue deformation. …”
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Using Structural Class Pairing to Address the Spatial Mismatch Between GEDI Measurements and NFI Plots by Nikola Besic, Sylvie Durrieu, Anouk Schleich, Cedric Vega

“…Beginning with the prediction of profile structural classes and shapes on NFI plots, the proposed method ultimately projects actual measurements onto the NFI plot sites through profile pairing within the predicted structural classes. …”
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Parametric Analysis of Static–Dynamic Characteristics of Adjacent Tunnels in Super-Large Twin Tunnels by DEM by Lin Wu, Zhuoyuan Cao, Xiaoya Bian, Jiayan Wang, Hong Guo

“…A numerical model of super-large-diameter (<i>D</i> = 15.2 m) twin tunnels was established by the discrete element method (DEM) to analyze the static and dynamic responses of adjacent tunnel structures and surroundings under train-induced vibrations. …”
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Estevez–Mansfield–Clarkson equation: Investigation of Breathers, two waves, and solitary wave solutions in shallow water phenomena and engineering fluid dynamics by U. Younas, J. Muhammad, T.A. Sulaiman, H.F. Ismael, Homan Emadifar, Wael W. Mohammed, Karim K. Ahmed

“…This article focuses on investigating the Estevez–Mansfield–Clarkson equation describing the complex dynamics of shallow water waves and the physics of fluids. …”
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Forecasting with a Bivariate Hysteretic Time Series Model Incorporating Asymmetric Volatility and Dynamic Correlations by Hong Thi Than

“…This study explores asymmetric volatility structures within multivariate hysteretic autoregressive (MHAR) models that incorporate conditional correlations, aiming to flexibly capture the dynamic behavior of global financial assets. …”
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Design and parameter identification of the wireless torque test system for hybrid vehicles by LI Jie, ZHOU Yijian, GENG Chong, PANG Jinlu

“…To solve this problem, an innovative embedded torque test system based on the wireless technology was designed.MethodsConsidering the internal spatial structure of the vehicle transmission system, a rotor-stator system was established based on the telemetry technology. …”
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Numerical simulation of crack propagation behavior of a semi-cylindrical specimen under dynamic loading by Ghorban Khandouzi, Mohsen Mollashahi, Mojtaba Moosakhani

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A Spatio-Temporal Tensor Graph Neural Network-Based Method for Node-Link Prediction in Port Networks by Zhixin Xia, Zhangqi Zheng, Feiyang Wei, Yongshan Liu, Lu Yu

“…Port network information security has received extensive attention in recent years, in which the prediction of node links in the network is significant. A Port network is a dynamic network, and its structure changes continuously with time. …”
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Investigating the Hydraulic Efficiency of the Labyrinth Weir Using the Flow3D Numerical Method by R. Daneshfaraz, M. Majedi Asl, T. OmidPour Alavian

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Flow and heat transfer characteristics of 3D printed sheet and solid triply periodic minimal surfaces porous structures by Jiajie Hu, Wei Xu, Huixin Liang, Jianping Shi, Wenlai Tang, Baocheng Guo, Jiquan Yang, Liya Zhu

“…The heat transfer performance of different TPMS structures and the fin structure was researched by means of computational fluid dynamics (CFD) simulations and experimental methods. …”
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Evolution characteristics of stress field during crosscut tunneling in soft coal seams and prevention and control technologies for gas dynamic disasters by Jiang WANG, Jianguo WU, Mingqiang WANG, Lianhe GUAN, Xiong XIAO, Xu YU, Cheng ZHAI

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Modeling Viral Capsid Assembly: A Review of Computational Strategies and Applications by Wenhan Guo, Esther Alarcon, Jason E. Sanchez, Chuan Xiao, Lin Li

“…Significant progress in studying viral capsid assembly has been achieved through various computational approaches, including molecular dynamics (MD) simulations, stochastic dynamics simulations, coarse-grained (CG) models, electrostatic analyses, lattice models, hybrid techniques, machine learning methods, and kinetic models. …”
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Model updating method for detect and localize structural damage using generalized flexibility matrix and improved grey wolf optimizer algorithm (I-GWO) by Sina Sadraei, Majid Gholhaki, Omid Rezaifar

“…This study’s main goal is to evaluate the location and extent of damage by combining two dynamically evolving parameters: the structure’s frequency and the generalized flexibility matrix. …”
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In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV) by S Ramya, R Shri Varshini, Sri R Poojaa, Prabhu Puniethaa

“…Through In silico approach the physicochemical properties secondary and tertiary structures and functional annotations of the matrix protein are analyzed, results indicate that the VSIV matrix protein is dominated by alpha-helical regions with a consistent tertiary structure validated by quality assessment methods. …”
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Study on the effects of initial stress and imperfect interface on static and dynamic problems in thermoelastic laminated plates by Yunying Zhou, Jiahuan Liu, Hong Mei, Dinggui Hou, Zhijie Yue, Yunxia Zhang

“…By employing the state-space method and introducing the interface transfer matrices for both elastic and thermal fields, this approach is convenient and efficient for multi-layer or thermoelastic coupled structures. …”
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