Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen by Amr A. Abd-Elghany, Ebtesam A. Mohamad, Abdullah Alqarni, Mohammed A. Hussein, Mohamed S. Mansour

“…Additionally, molecular docking studies were conducted to assess the binding affinity of diosgenin with specific proteins. Molecular dynamics simulations were conducted on CDK4, AKT, and CDK6 proteins with diosgenin using GROMACS. …”
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The use of low doses of gabapentin in patients with neuropathic pain and with thrombocytopenia by O. K. Levchenko, E. G. Gemdzhian, G. M. Galstyan

“…Gabapentin is used as a first-line drug for neuropathic pain (NP), but has been poorly studied in patients with blood system diseases.The objective was to study the effectiveness and safety of gabapentin in patients with blood system diseases with chronic pain.Materials and methods. A single-center, prospective observational study included 24 patients with thrombocytopenia and pain between October 2017 and October 2022. …”
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Prompt Framework for Extracting Scale-Related Knowledge Entities from Chinese Medical Literature: Development and Evaluation Study by Jie Hao, Zhenli Chen, Qinglong Peng, Liang Zhao, Wanqing Zhao, Shan Cong, Junlian Li, Jiao Li, Qing Qian, Haixia Sun

“… BackgroundMeasurement-based care improves patient outcomes by using standardized scales, but its widespread adoption is hindered by the lack of accessible and structured knowledge, particularly in unstructured Chinese medical literature. …”
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Non-targeted metabolomics and network pharmacology of Taohong Siwu Decoction in hepatic fibrosis mouse model using high resolution mass spectrometry by Shengsheng Li, Shengsheng Li, Shenglan Qi, Rongsheng Li, Fangming Yang, Zhenyi Niu, Wei Liu, Suping Ma, Zhun Xiao

“…Furthermore, molecular dynamics simulations were conducted to evaluate the structural stability and binding interactions. …”
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Family-to-work conflict linked to psychological distress and family life satisfaction during the second year of the COVID-19 pandemic in dual-earner parents with adolescents by Berta Schnettler, Berta Schnettler, Berta Schnettler, Berta Schnettler, Edgardo Miranda-Zapata, Ligia Orellana, Ligia Orellana, Mahia Saracostti, Mahia Saracostti, Héctor Poblete, Andrés Concha-Salgado, Germán Lobos, Cristian Adasme-Berríos, María Lapo, Katherine Beroiza, Leonor Riquelme-Segura, José A. Sepúlveda, José A. Sepúlveda, Enid Thomas

“…IntroductionResearch on work-family dynamics during the COVID-19 pandemic shows that family demands increased for workers, particularly those with children. …”
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COVID‐19 and Healthcare Workers Burnt out: A Qualitative Study of Burnout Experiences of Healthcare workers in a Secondary Hospital in Ghana by Seth Christopher Yaw Appiah, Elvis Mwinsome Sobiesuo, Bernard Obeng, Elsie Asamoah, Comfort Badu Mantey, Peter Dwumah, Mary Sefa Boampong, Abena Afrakomah Boateng, Richard Ofori, Michael Nimoh, Josephine Boakyewaa Nyarko, Jonathan Mensah Dapaah

“…Design Descriptive phenomenological design. Methods The study adopted a qualitative approach, anchored on a descriptive phenomenological design to explore the dynamics of burnt‐out experienced by 12 healthcare staff at the Kwame Nkrumah University of Science and Technology (KNUST) hospital in Ghana during the COVID‐19 pandemic. …”
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The Effect of High Nitric Oxide Concentrations on Oxygenators in Cardiopulmonary Bypass Machines (Experimental Study) by A. M. Radovskiy, I. V. Vorotyntsev, A. A. Atlaskin, A. N. Petukhov, S. S. Kryuchkov, M. E. Atlaskina, A. N. Stepakova, A. O. Marichev, E. K. Barygin, V. V. Osovskikh, V. D. Selemir, S. N. Buranov, V. V. Golovanov, A. S. Shirshin, Yu. V. Valueva, V. V. Pichugin, S. E. Domnin, A. E. Bautin

“…NO, NO2 (at the inlet and outlet of the oxygenator), and the dynamics of methemoglobin were evaluated. After weaning of animals from CPB, the oxygenators were tested for leakproofness, and scanning electron microscopy (SEM) was performed.Results. …”
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CLINICAL ASPECTS OF PATIENTS WITH NON-REMOVABLE PROSTHESIS RESULTS OF ZRO2 COATED PROSTHESES by O.M. Yakovyn, Z.R. Ozhohan

“…Thus, analyzing the results of the research can be argued that in patients of group 1st after treatment was improved clinically, and periodontal status in chronological dynamics remained satisfactory. In patients of group 2nd for who orthopedic structures made of CСA and NCA with bioinert coating of ZrO2 were offered, in their indicators of periodontal tissues were close to data observed in patients within 3rd group with metal structures. …”
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Ayahuasca-inspired DMT/HAR formulation reduces brain differentiation between self and other faces by Dila Suay, Helena D. Aicher, Micheal Kometer, Michael J. Mueller, Luzia Caflisch, Alexandra Hempe, Camilla P. Steinhart, Claudius Elsner, Ilhui A. Wicki, Jovin Müller, Daniel Meling, Dario A. Dornbierer, Milan Scheidegger, Davide Bottari

“…This effect underscores the serotonergic modulation of face recognition and suggests a reorganization of self-related neural dynamics under psychedelics. By reducing self-other differentiation, psychedelics may promote cognitive and emotional flexibility. …”
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Genealogy of the Arab tribes living in Syria during the Caliphate of Imam Ali (AS)Typology of the Arab Tribes Living in the Levant during the Caliphate of Imam Ali (AS) Typology... by Akram sadat Hoseini, Yahya Mirhoseini

“…Moreover, the research revealed that in all the mentioned groups, the Qahtani tribes were dominant, shedding light on the internal dynamics and power structures within the Levantine community during this pivotal period of Islamic history. …”
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Assessing neonatal brain glymphatic system development using diffusion tensor imaging along the perivascular space and choroid plexus volume by Ting Peng, Ying Lin, Xin Xu, Jiaqi Li, Miaoshuang Liu, Chaowei Zhang, Xiaohui Liao, Xiaoshan Ji, Zhongmeng Xiong, Zhuoyang Gu, Xinyi Cai, Tianli Tao, Yajuan Zhang, Lixuan Zhu, Deyi Zhuang, Xianghui Huang, Man Xiong, Peng Zhang, Jungang Liu, Guoqiang Cheng

“…We investigated non-invasive magnetic resonance imaging (MRI) biomarkers of glymphatic system and their developmental correlates in neonates. Methods In 117 neonates undergoing high-resolution T1-weighted and diffusion MRI, we quantified two glymphatic metrics: (1) diffusion tensor imaging along the perivascular space (DTI-ALPS) index, reflecting perivascular fluid dynamics; (2) choroid plexus (CP) volume, a cerebrospinal fluid (CSF) production marker. …”
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THE INFLUENCE OF HEART RATE VARIABILITY ON CLINICAL COURSE OF CHRONIC HEART FAILURE AND RENAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS by E. A. Polyanskaya, S. V. Mironova, N. A. Koziolova

“…Aim. Evaluation of structural and functional condition of the left ventricle (LV) and kidneys in permanent atrial fibrillation patients (AF) with ischemic chronic heart failure (CHF) according to mean 24 hour heart rate and heart rate variability.Material and methods. …”
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Exploration of Collective Coexistence and Social Governance of Water: A Study of the Citizens of Semirom by Mahmoud Ghasemi, Azimeh Sadat Abdelahi

“…The research participants comprised citizens and water experts from Semirom. The sampling method was purposive based on semi-structured interviews conducted with 30 individuals from the local community and the water sector. …”
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Brain physiological pulsations are linked to sleep architecture and cognitive performance in older adults by Rodolphe Nenert, Christina Mueller, Corina Catiul, Jennifer Pilkington, Pierre LeVan, Ayushe Sharma, Jerzy P. Szaflarski, Amy W. Amara

“…These findings suggest that glymphatic efficiency, as reflected by brain pulsations, is closely linked to sleep quality and cognitive performance in older adults, particularly involving cortical and subcortical structures relevant to cognitive and sleep regulatory functions. …”
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Interpersonal and systemic factors in initiating, developing and maintaining collaborations between European neurosurgical departments and institutions in low-resources settings: A... by Nicolò Marchesini, Vicki M. Butenschoen, Andreas K. Demetriades, Said Idrissa Ahmada, Fazlul Hoque, Thomas Kapapa, Patrick D. Kamalo, Pablo González-López, Rupavathana Mahesperan, Ondra Petr, Wilco Peul, Nicephorus Boniface Rutabasibwa, Ellianne J. dos Santos Rubio, Abenezer Tirsit Aklilu, Jake Timothy, Enoch O. Uche, Magnus Tisell

“…Research question: What are the most salient interpersonal and systemic factors relevant to the a) initiation, b) development, and c) maintenance of effective and sustainable collaborations between European neurosurgical departments and institutions in resource-limited settings? Material and methods: We conducted a prospective qualitative study using semi-structured interviews with fourteen matched neurosurgeons—seven from European centers and seven from LMIC institutions—engaged in such collaborations. …”
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Co-circulation and genetic characterization of genotype I and II feline bocavirus strains in domestic cats from Northern Vietnam by Hieu Van Dong, Giang Thi Huong Tran, Yen Hoang Thi Nguyen, Thiet Chi Ngo, Amonpun Rattanasrisomporn, Chaiwat Boonkaewwan, Dao Anh Tran Bui, Jatuporn Rattanasrisomporn

“…DNA was extracted and screened for FBoV using conventional polymerase chain reaction targeting the non-structural (NS)-1 gene. Positive samples were subjected to Sanger sequencing, and partial NS1 sequences were analyzed using MEGA X for phylogenetic inference. …”
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Key Drivers Affecting the Future of Power Relations in Tehran Metropolis with a Scenario-Writing Approach by Afshin Mottaghi, Arash Ghorbani Sepehr, Joseph Saloukadz

“…Structural analysis of the research question was conducted using the MICMAC software and Scenario Wizard, employing the Cross-Impact Balance (CIB) method. …”
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Rational Approach to New Chemical Entities with Antiproliferative Activity on Ab1 Tyrosine Kinase Encoded by the <i>BCR-ABL</i> Gene: An Hierarchical Biochemoinformatics Analysis by Vitor H. da S. Sanches, Cleison C. Lobato, Luciane B. Silva, Igor V. F. dos Santos, Elcimar de S. Barros, Alexandre de A. Maciel, Elenilze F. B. Ferreira, Kauê S. da Costa, José M. Espejo-Román, Joaquín M. C. Rosa, Njogu M. Kimani, Cleydson B. R. Santos

“…In the prediction of biological activity, the results of the nine selected structures ranged from 13.7% < Pa < 65.8%, showing them to be potential protein kinase inhibitors. …”
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Suppressing lipid biosynthesis in Mycobacterium tuberculosis through polyketide synthase 13 thioesterase inhibition: Insights from computational analysis by Maha M. Alawi, Hattan S. Gattan, Azzah S. Alharbi, Mohammed H. Alruhaili, Ibrahim A. Al-Zahrani, Saad B.AL Masaud, Vivek Dhar Dwivedi, Esam I. Azhar

“…In silico virtual screening was done on top candidates using MTiOpenScreen based on binding affinity. The molecular dynamics simulation was applied to analyze the structural properties in terms of stability, compactness, and flexibility of the post-validation of the docking result. …”
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Multi-Focused Acoustic Radiation Force Impulse Modulation of Murine Hepatic Xenografts Enhances Nanoscale DOX@Lip Delivery and Therapeutic Effect by Wu S, Wang C

“…Subsequently, murine xenograft models were established and underwent MF-ARFI preconditioning before DOX@Lip injection. Tumor volume dynamics and body weight changes were longitudinally monitored. …”
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