Enhanced production of thermostable catalase for efficient gluconic acid biocatalysis by Jiang Huang, Jiang Huang, Jun Wang, Jun Wang, Jinling He, Jinling He, Yupeng Wu, Yupeng Wu, Lizhi Chen, Lizhi Chen, Shuangzi Zhou, Shuangzi Zhou, Yeyu Bian, Yeyu Bian, Yangyuan Li, Yangyuan Li

“…Simultaneously, we used AlphaFold2 for structural predictions and conducted in-depth analyses via accelerated molecular dynamics simulations.Results and discussionWe successfully obtained a strain with the highest catalase activity by optimizing signal peptides and overexpressing the crucial heme synthesis enzyme. …”
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The Effect of Enhanced External Counterpulsation on the Vascular State, Indicators of Glycemic Control and Quality of Life in Patients with Coronary Artery Disease and Type 2 Diabe... by O. A. Slepova, A. S. Lishuta, E. Yu. Vasiltsova, E. V. Privalova, Yu. N. Belenkov

“…To study the effect of enhanced external counterpulsation (EECP) on the functional status, quality of life, structural and functional state of the vascular bed, and markers of glycemic control in patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM).Material and methods. …”
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Quantifying conformational changes in the TCR:pMHC-I binding interface by Benjamin McMaster, Benjamin McMaster, Christopher J. Thorpe, Christopher J. Thorpe, Jamie Rossjohn, Jamie Rossjohn, Charlotte M. Deane, Hashem Koohy

“…Thus, it remains an open question of whether movement occurs in the binding interface that enables the recognition and activation of T cells.MethodsIn this work, we quantify the conformational changes in the TCR:pMHC-I binding interface by creating a dataset of 391 structures, comprising 22 TCRs, 19 MHC alleles, and 79 peptide structures in both unbound (apo) and bound (holo) conformations.ResultsIn support of some case studies, we demonstrate that all complementarity determining region (CDR) loops move to a certain extent but only CDR3α and CDR3β loops modify their shape when binding pMHC-Is. …”
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Effectiveness of Multisport Play-Based Practice on Motor Coordination in Children: A Cross-Sectional Study Using the KTK Test by Nicola Mancini, Rita Polito, Francesco Paolo Colecchia, Dario Colella, Giovanni Messina, Vlad Teodor Grosu, Antonietta Messina, Siria Mancini, Antonietta Monda, Maria Ruberto, Fiorenzo Moscatelli

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Assessment on drag force distribution of a semi-submersible truss fish cage in currents by Hang-Fei Liu, Xiaohua Huang, Guoliang Pang, Gen Li, Taiping Yuan, Yu Hu, Qiyou Tao, Qiyou Tao

“…Assessing the current forces exerted on a semi-submersible truss fish cage is crucial for understanding drag force distribution and ensuring the structural safety. The present study employs computational fluid dynamics (CFD) methods and porous media theory to predict the drag forces on a semi-submersible truss fish cage, providing a detailed description of the magnitude and distribution patterns of drag forces on the plane nets, pontoons, columns, and braces. …”
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Moisture Ingress in Building Envelope Materials: (II) Transport Mechanisms and Practical Mitigation Approaches by Itzel Lopez-Carreon, Esrat Jahan, Mohammad Hossein Yari, Elnaz Esmizadeh, Marzieh Riahinezhad, Michael Lacasse, Zhe Xiao, Elena Dragomirescu

“…The primary goal of this review is to explore both the fundamental dynamics of moisture ingress and practical strategies for its mitigation. …”
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Deviance detection and regularity sensitivity in dissociated neuronal cultures by Zhuo Zhang, Amit Yaron, Dai Akita, Tomoyo Isoguchi Shiramatsu, Zenas C. Chao, Hirokazu Takahashi, Hirokazu Takahashi

“…They also suggest new directions for the development of neuro-inspired artificial intelligence systems, emphasizing the importance of incorporating adaptive mechanisms and temporal dynamics in the design of neural networks.…”
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Linking family violence and children's trauma symptoms through attachment and emotional insecurity by Anna L.C. van Loon-Dikkers, Bas Tierolf, Carlo Schuengel, Majone J. Steketee

“…They were contacted through child protection services. Methods: Participants completed questionnaires about CAN, IPV, attachment security, emotional insecurity, and PTSS. …”
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Identifying factors influencing emerging innovations in hospital discharge decision making in response to system stress: a qualitative study by Allison M. Gustavson, Matthew J. Miller, Natassia Boening, Emily M. Hudson, Jennifer P. Wisdom, Robert E. Burke, Hildi J. Hagedorn

“…Abstract Background The purpose of this qualitative study was to identify emergent rehabilitation innovations and clinician perceptions influencing their implementation and outcomes related to hospital discharge decision-making during the Coronavirus 2019 pandemic. Methods Rehabilitation clinicians were recruited from the Veterans Affairs Health Care System and participated in individual semi-structured interviews guided by the integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework. …”
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EU DEMOGRAPHIC CHARACTERISTICS: GLOBAL MEGATRENDS AND OPPORTUNITIES FOR THE RETAIL SECTOR by Олена Сергієнко, Світлана Прокопович, Марина Татар, Олександр Білоцерківський, Олександр Чернов, Олександр Кизлюк

“…The research employs factor analysis and multidimensional assessment methods to quantify the influence of demographic indicators, incorporating both stimulating and disincentive effects on retail market dynamics. …”
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ANTI-CORRUPTION AUDIT OF COMPANIES AND FORESIGHT ANALYSIS IN TERMS OF THE STATE'S EUROPEAN INTEGRATION ECONOMIC POLICY by Анастасія Майстренко, Каріна Назарова, Тетяна Копотієнко, Роман Овчарик, Вікторія Міняйло, Наталія Шалімова

“…Accounting criminal and administrative violations by types of corruption during 2019-2023 were studied. The structural analysis of violations for 2019-2022 shows that the top three corruption methods included: an offer, a promise or the granting of an undue advantage to an official (21,9%); failure to take appropriate measures to combat corruption crimes (15,7%); declaring false information (12,8%). …”
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Patellar motion and dysfunction of its stabilizers in a biomechanical model of the knee joint by A. S. Yurova, A. I. Tyagunova, F. B.  Loginov, Yu. V. Vassilevski, A. V. Lychagin, E. B. Kalinsky, E. V. Larina, N.  V. Gorohova, K. A. Devyatyarov, O. N. Bogdanov, I. B. Kovalenko, K. V. Chesnokova, M. A.  Dergachev, E. Yu. Mychka, O. N. Kosukhin

“…The presented biomechanical model provides a detailed analysis of the normal dynamics of the patella and the role of different anatomical structures in its functioning and can be used for further experiments investigating of the patellar movement. …”
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Detecting Galactic Rings in the DESI Legacy Imaging Surveys with Semisupervised Deep Learning by Jianzhen Chen, Zhijian Luo, Cheng Cheng, Jun Hou, Shaohua Zhang, Chenggang Shu

“…The ring structures of disk galaxies are vital for understanding galaxy evolution and dynamics. …”
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Endogenous auxin and abscisic acid in regulation of Equisetum arvense L. sporophyte growth and development by Lesya Voytenko, Inna Grigorchuk, Mykola Shcherbatiuk, Oleksandr Polishchuk, Olga Tsvilynyuk, Iryna Kosakivska

“…While extensive research exists on the role of IAA and ABA in the growth and morphogenesis of higher flowering plants, their roles in vascular spore-bearing plants remain poorly understood. Materials and Methods. This study examined the dynamics and distribution of endogenous IAA and ABA in the organs of reproductive and sterile plants of the sporophyte generation of Equisetum arvense L. across nine ontogenetic phases, using HPLC-MS analysis. …”
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Bibliometric Analysis And Visualization Of Funding Social Housing: Connection Of Sociological And Economic Research by Svitlana Ianchuk

“…Methodological tools of the research methods were logical generalization and scientific abstraction, statistical and structural analysis, comparative, and graphical analysis using Excel 2010 software, Scopus database tools and VOSViewer software package v.1.6.16. …”
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One Health interventions for leptospirosis: Do we need an engineer? by Prof Simon Reid, Dr Mike Kama, Dr Russell Richards, Dr Nicholas Osborne, Mr Suliasi Batakawai, Ms Kathryn Vitangcol, Dr Oz Sahin

“…Methods: A multidisciplinary team used a participatory model-building process to develop a qualitative (causal loop diagram (CLD)) representation of the system structures that drive the incidence of leptospirosis in Fiji. …”
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Prognostic value of vascular remodeling parameters in the development of adverse cardiovascular events in patients with gastric cancer by Y. Yu. Kirichenko, I. S. Ilgisonis, P. A. Levin, Y. N. Belenkov

“…To determine a possible prognostic marker for adverse cardiovascular events in patients with gastric cancer by studying the early and long-term effects of multiagent chemotherapy (MAC) on the structural and functional vascular wall parameters.Material and methods. …”
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The First Fifth-Generation District Heating and Cooling System in Kazakhstan: Planning and Design by Stanislav Chicherin, Yana Zhuikova, Tatyana Pyanykh, Andrey Zhuikov, Galym Baidyussenov, Saule Abildinova

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New spirooxindole-thiazolidine derivatives as antiseizure agents: Biological evaluation and computational studies by Leila Emami, Leila Moezi, Pegah Mardaneh, Sara Sadeghian, Elaheh Ataollahi, Masoumeh Divar, Sahar Zarei, Saeed Agah, Razieh Sabet, Soghra Khabnadideh

“…To investigate interactions with the GABA-A receptor, molecular docking and dynamics simulations were carried out. Statistical analysis was performed using ANOVA, and the results were presented as means ± SEM. …”
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Myeloid dendritic cells and periodontal disease association: integrated study of single-cell sequencing and Mendelian randomization analysis by ChengJi Shi, XinYi Ou, XiaoXu Lei, LiJuan Huang, ShuHao Xu, Wei Li, Xi Zhao

“…BackgroundPeriodontal disease is a widespread inflammatory condition that compromises the supporting structures of the teeth, potentially resulting in tooth loss if left untreated. …”
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