Microbial dysbiosis and its diagnostic potential in androgenetic alopecia: insights from multi-kingdom sequencing and machine learning by Xiaochen Wang, Fengjuan Li, Yangyang Sun, Fan Meng, Yaolin Song, Xiaoquan Su

“…Thus, we introduce the microbial index of scalp health (MiSCH), which leverages microbiome data for the early detection and severity prediction of AGA. This method is especially valuable for identifying people at risk of developing more severe hair loss, even before visible symptoms appear. …”
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Urban patriotism in the media space of Ekaterinburg: Cases of “Public Garden”, “Lion on Weiner Street”, “Toporkov’s House” by Liya M. Khakimzyanova, Vera S. Kharchenko

“…Social changes also change the appearance of civic activism, which is a structural component and one of the active strategies of urban patriotism. …”
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Effects of physical exercise on physical and mental health-based on the test of mediation and moderation effect by Xiaomei Mo, Wenlong Zhao

“…However, there is currently a paucity of research exploring the underlying mechanisms through which physical exercise impacts mental and physical health.MethodsIn this study, 9,954 sample data points from the 2018 China Labor Force Dynamics data were selected to verify the relationship between physical exercise, life satisfaction, and physical and mental health using Ordinary Least Squares regression. …”
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Causal AI Recommendation System for Digital Mental Health: Bayesian Decision-Theoretic Analysis by Mathew Varidel, Victor An, Ian B Hickie, Sally Cripps, Roman Marchant, Jan Scott, Jacob J Crouse, Adam Poulsen, Bridianne O'Dea, Sarah McKenna, Frank Iorfino

“…The causal processes are assumed to follow a structural causal model, where the posterior distribution of structural causal models is estimated using a Markov chain Monte Carlo method. …”
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Using black knowledges to recognise and address barriers to COVID-19 vaccination in Malawi by Chúk Odenigbo, Paul Mkandawire, Sonia Wesche, Eric Crighton

“…This research centres Malawi as a case study and seeks to (1) identify barriers to COVID-19 vaccination; (2) situate these barriers within geographic scales, ranging from the local to the global; and, (3) identify the role of the (Black) individual in creating, perpetuating, navigating and overcoming these barriers. Methods The study employed a qualitative approach, using in-depth semi-structured interviews with 41 key informants in Malawi between September and December 2021 to explore barriers to vaccination. …”
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Demographic development of the countries of Northern Europe: current trends for the Ukrainian experience by Ірина Гудзеляк

“…Using the statistical method, the dynamics of the population, the main indicators of demographic processes and structures, migration and ethno-structural changes were assessed. …”
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A hybrid CFD and machine learning study of energy performance of photovoltaic systems with a porous collector: Model development and validation by Yinling Wang, Lei Yu, Mazhar Ali, Imran Ali Khan, Tahir Maqsood, Haining Gao, Qi Wang, Xiaolei Guo

“…These results demonstrated the capability of machine learning to accurately capture complex relationships within structured datasets.…”
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Lessons from using the Normalisation Process Theory to understand adherence to guidance on MgSO4 in preterm labour by Christalla Pithara-McKeown, Tracey Stone, Emma Treloar, Jenny Donovan, Karen Luyt, Sabi Redwood

“…Their work relied on backfill funding and protected time, and social-cognitive and social-structural resources in their settings. Sense-making, cognitive participation, collective action and reflexive monitoring work took place iteratively and dynamically within and across these structures on each level of the system. …”
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MODULATION AS A MULTIMODAL TRANSLATION STRATEGY OF GRAPHIC NOVEL PERSEPOLIS BY M. SATRAPI by Anna V. Khodorenko

“…The methodology, therefore, combines a qualitative approach with methods of observation, description, and comparison, alongside elements of multimodal discourse analysis. …”
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Management and Operation Transformation of Urban Park Green Spaces from the Perspectives of Public Goods Provision and Fiscal Sustainability by Peiyi JIA

“…By integrating theoretical frameworks of quasi-public goods with fiscal challenges, the research aims to propose institutional pathways for sustainable park governance aligned with China’s high-quality development agenda, emphasizing ecological preservation, social equity, and economic resilience.MethodsThe research employs an integrated analytical framework to systematically investigate the dynamic interplay between urbanization processes, fiscal capacities, and park governance mechanisms, with a focus on supply-demand evolution across historical phases. …”
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Novel Potent and Selective Dopamine D4 Receptor Piperidine Antagonists as Potential Alternatives for the Treatment of Glioblastoma by Federica Matteucci, Pegi Pavletić, Alessandro Bonifazi, Rian Garland, Hideaki Yano, Consuelo Amantini, Laura Zeppa, Emanuela Sabato, Giulio Vistoli, Valerio Mammoli, Loredana Cappellacci, Fabio Del Bello, Gianfabio Giorgioni, Riccardo Petrelli, Alessia Piergentili, Wilma Quaglia, Alessandro Piergentili

“…In this study, new piperidine-based ligands, analogs of the potent and selective D4R compounds 77-LH-28-1 (<b>7</b>) and its 4-benzyl analog <b>8</b>, were synthesized and studied to investigate the effects produced by variations in the distances between the pharmacophoric features on the D4R affinity and selectivity. <b>Methods</b>: All the new compounds <b>9–20</b> were evaluated for their radioligand binding affinity at D2-like receptor subtypes and the results were rationalized by docking studies and molecular dynamics (MD) simulations. …”
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Genomic interrogation of invasive group A Streptococcus (iGAS) epidemiology and COVID-19 impacts in Victoria, Australia: a 6-year retrospective studyResearch in context by Jacqueline M. Morris, Jake A. Lacey, Kerrie Stevens, Lamali Sadeesh Kumar, Mathilda Wilmot, Janet Strachan, Marion Easton, Daneeta Hennessy, Tony M. Korman, Andrew J. Daley, Katherine B. Gibney, Adam W.J. Jenney, Steven Y.C. Tong, Benjamin P. Howden, Norelle L. Sherry

“…Genomic analyses were conducted to determine the epidemiology, genetic diversity, and population dynamics of iGAS. Findings: Analysis of 955 confirmed iGAS cases over a 6-year period revealed a polyclonal population. …”
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Mannich Base Derived from Lawsone Inhibits PKM2 and Induces Neoplastic Cell Death by Lucas Rubini-Dias, Tácio V. A. Fernandes, Michele P. de Souza, Déborah Hottz, Afonso T. Arruda, Amanda de A. Borges, Gabriel Ouverney, Fernando de C. da Silva, Luana da S. M. Forezi, Gabriel Limaverde-Sousa, Bruno K. Robbs

“…Docking studies and molecular dynamics calculations were performed using Autodock 4 and GROMACS, respectively, on the tetrameric PKM2 crystallographic structure. …”
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Robust self-supervised denoising of voltage imaging data using CellMincer by Brice Wang, Tianle Ma, Theresa Chen, Trinh Nguyen, Ethan Crouse, Stephen J. Fleming, Alison S. Walker, Vera Valakh, Ralda Nehme, Evan W. Miller, Samouil L. Farhi, Mehrtash Babadi

“…Traditional denoising methods, such as matrix factorization, impose rigid assumptions about noise and signal structures, while existing deep learning approaches fail to fully capture the rapid dynamics and complex dependencies inherent in voltage imaging data. …”
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Thermodynamic Characterization of Solar Wind Interaction Regions Using PSP Observations: Evidence of Subadiabatic and Superadiabatic States by Mohit Shah, Anil Raghav, Kalpesh Ghag, Omkar Dhamane, Kishor Kumbhar, Georgios Nicolaou, Ankush Bhaskar, R. C. Allen, Zubair Shaikh

“…Instead, it reflects varying heating and cooling processes and/or degrees of freedom within these structures, contributing to a deeper understanding of SIR dynamics.…”
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Using optimized dimensionality reduction and machine learning to explain driving processes of phytoplankton community assembly in large mountain rivers by Jingxu Ye, Daikui Li, Qi Liu, Jianying Song, Jiawei Song, Zhigang Zu, Yujun Yi

“…The seasonal variations of phytoplankton are associated with significantly different roles of deterministic factors across seasons. We offer a method for analyzing the aquatic community assembly and provide a theoretical basis to support future dynamics prediction of phytoplankton.…”
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Irisin attenuates cardiac injury and improves prognosis in rats with hemorrhagic shock by maintaining mitochondrial homeostasis via the AMPK/Drp1 pathway by Zheng Zhang, Zheng Zhang, Zheng Zhang, Yufang Zhang, Yufang Zhang, Xiaofang Zou, Jiake Li, Yunfei Chi, Hailiang Bai, Bin Wei, Huiting Yun, Huiting Yun, Quanxi Zhang, Quanxi Zhang, Weihua Cao, Haiyan Liu, Hongjie Duan

“…This modulation of mitochondrial dynamics preserved cardiomyocyte mitochondrial membrane potential (MMP), ATP production, and structural integrity. …”
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q-Breathers in the diatomic β-Fermi–Pasta–Ulam–Tsingou chains by Lin Deng, Hang Yu, Zhigang Zhu, Weicheng Fu, Yisen Wang, Liang Huang

“…These results not only expand the applicability of QBs but also offer significant implications for understanding the thermalization dynamics in complex lattice structures, with wide potential applications in related low-dimensional materials.…”
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Resilience of Gen Z to Socioeconomic Challenges: The Interconnection of Family Financial Socialization, Attitudes Towards Money and Financial Well-being by Manoj Kumar Chaudhary, Madan Dhungana, Manoj Subedi, Harjit Singh, Dinesh Mani Ghimire

“…Between September and December 2024, a structured questionnaire was distributed both physically on campuses and digitally via online platforms to collect primary data from 452 Gen Z students (aged 18–28) enrolled in 10 management colleges affiliated with national and international universities operating in Kathmandu, Nepal, selected through a purposive sampling method. …”
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Computational and experimental analysis of flow velocity and complex vortex formation around a group of bridge piers by Nima Ikani, Jaan H. Pu, Prashanth Reddy Hanmaiahgari, Bimlesh Kumar, Ebrahim Hamid Hussein Al-Qadami, Mohd Adib Mohammad Razi, Shu-yan Zang

“…This research contributes to a deeper understanding of flow dynamics around complex interactive pier systems, which is critical for designing stable and sustainable hydraulic structures. …”
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