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8241
The quest for environmental analytical microbiology: absolute quantitative microbiome using cellular internal standards
Published 2025-01-01“…The resulting microbial composition (community structure) data are essential for environmental analytical microbiology, enabling characterization of community dynamics and assessing microbial pollutants for the development of intervention strategies. …”
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8242
Association of Concave Deformity of the Anterior Scalene on Magnetic Resonance Imaging with Vascular Variant of Neurogenic Thoracic Outlet Syndrome
Published 2024-10-01“…The second aim was to define the NTOS vascular subtypes and establish possible treatments. Methods:. We retrospectively reviewed patients who met the Consortium for Research and Education on Thoracic Outlet Syndrome criteria for NTOS and were operated on after a failed rehabilitation program. …”
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8243
A Modern View on the Treatment for Acute Calcium Channel Blocker Poisoning
Published 2024-09-01“…To evaluate the effectiveness of methods for the treatment of acute calcium channel blocker (ССВ) poisoning according to the literature. …”
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8244
Adaptive evaluation of gross total resection rates for endoscopic endonasal approach based on preoperative MRI morphological features of pituitary adenomas
Published 2024-12-01“…It explores the impact of the dynamic relationships between different anatomical landmarks and the tumor on the resection rate and tumor progression/recurrence during the endoscopic endonasal approach (EEA).MethodsA single-center institutional database review was conducted, identifying patients with PAs treated with EEA from December 2018 to January 2023. …”
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8245
Anemia and blood transfusions in myelofibrosis: economic and organizational impact on Italian patients, caregivers and hospitals
Published 2025-03-01“…The BEAT project aimed to quantify the economic and organizational burden of anemia and transfusions in MF patients in Italy from the patient and hospital perspectives.MethodsData were collected from two primary sources: (i) semi-structured interviews with 13 hematologists and 1 transfusionist from 13 Italian MF reference centers; (ii) an online questionnaire completed by 191 patients distributed by AIPAMM (Italian Association of Patients with Myeloproliferative Diseases). …”
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8246
Regularities of crustal faulting and tectonophysical indicators of fault metastability
Published 2018-10-01“…In each fault body, a node can be distinguished as a fault part wherein the main structural and material transformations take place. …”
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8247
THE LEXICON OF CONTEMPORARY WAR TIME: COMPRESSIVE PROFESSIONAL SLANG UNITS IN THE UKRAINIAN LANGUAGE
Published 2024-12-01“…The objectives of the study are as follows: 1) to separate compressives from the traditional derivates; 2) to determine the criteria for distinguishing the main compressive processes – abbreviation and univerbation; 3) to formulate the causes of the emergence of the investigated slang; 4) to give reasoning for the study of compressives in military discourse as a pro- spective research issue. The main research methods include the descriptive and structural ones, as they help demonstrate the specificity of univerbs and abbreviation as instances of speech compression. …”
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8248
Staying afloat on a realm of shifting sands: carers navigating palliative care in their rural settings
Published 2025-07-01“…Locating our research in the interpretive paradigm, we sought to develop a conceptual framework to inform reflections and discussions to provide meaningful support for carers involved in palliative care in rural areas. Methods: Our qualitative research, undertaken in the interpretive paradigm, was informed by philosophical hermeneutics. …”
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8249
The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation.
Published 2021-01-01“…We conducted face-to-face and telephone-based semi-structured qualitative interviews with staff stakeholders. …”
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8250
Unfolding insights about resilience and its coping strategies by medical academics and healthcare professionals at their workplaces: a thematic qualitative analysis
Published 2025-02-01“…Conclusion The findings of our study bestow valuable insights into the dynamic nature of resilience in the medical profession. …”
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8251
Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions
Published 2025-02-01“…In this study we evaluated the effects of FDA-approved poly (D,L-lactide-co-glycolic) acid (PLGA) nanoparticles, which can inhibit amyloid-β aggregation/toxicity in cellular/animal models of AD, on temperature-dependent aggregation of 0N4R tau isoforms in vitro.Methods: We have used a variety of biophysical (Thioflavin T kinetics, dynamic light scattering and asymmetric-flow field-flow fractionation), structural (fluorescence imaging and transmission electron microscopy) and biochemical (Filter-trap assay and detection of soluble protein) approaches, to evaluate the effects of native PLGA nanoparticles on the temperature-dependent tau aggregation.Results: Our results show that the aggregation propensity of 0N4R tau increases significantly in a dose-dependent manner with a rise in temperature from 27°C to 40°C, as measured by lag time and aggregation rate. …”
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8252
AQP5 trafficking is regulated by its C-terminal tail and interaction with prolactin-inducible protein
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8253
Assessing the economic performance of agrivoltaic systems in vineyards – framework development, simulated scenarios and directions for future research
Published 2024-12-01“…The framework provides valuable guidance for future research and investment strategies, emphasizing the importance of: i) Long-term Trials: To evaluate viticultural impacts and synergistic benefits. Ii) Dynamic Models: Incorporating evolving revenue streams, cost structures, and regulatory impacts. iii) Broad Assessments: Exploring the environmental and social benefits of AVS alongside economic performance. …”
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8254
Sodium alginate microspheres loaded with Quercetin/Mg nanoparticles as novel drug delivery systems for osteoarthritis therapy
Published 2025-03-01“…Moreover, to avoid the adverse reactions linked to frequent injections, sodium alginate (SA) microspheres encapsulating Que-Mg2+ NPs (Que-Mg@SA) were designed to treat the H2O2-induced OA cell model. Methods Que-Mg@SA microspheres were synthesized using the ionotropic gelation technique, with calcium chloride acting as the cross-linking agent. …”
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8255
Green synthesis of silver nanoparticles (AgNPs) from G. stearothermophilus GF16: stable and versatile nanomaterials with antioxidant, antimicrobial, and catalytic properties
Published 2025-08-01“…Thermogravimetric analysis demonstrated excellent thermal stability with retention of structural integrity up to 120 °C, an exceptional feature among biogenic AgNPs. …”
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8256
Immune Regulation and Disulfidptosis in Atherosclerosis Influence Disease Progression and Therapy
Published 2025-04-01“…Despite extensive research, the intricate molecular mechanisms underlying its development and progression remain incompletely understood. <b>Methods:</b> Single-cell RNA sequencing (scRNA-seq) was employed to conduct a comprehensive mapping of immune cell enrichment and interactions within atherosclerotic plaques, aiming to investigate the cellular and molecular complexities of these structures. …”
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8257
Compliant buffer layer achieves native-like cartilage stress in talar prosthesis: a finite element analysis study
Published 2025-07-01“…The objective of this study was to identify the most suitable combination of buffering layer material and thickness for talar prosthesis. Methods This study employed dynamic biplane radiography (DBR) integrated with finite element analysis (FEA) to systematically evaluate how prosthetic material selection and buffering layer thickness affect periprosthetic cartilage biomechanics. …”
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8258
Gaming-Based Tele-Exercise Program to Improve Physical Function in Frail Older Adults: Feasibility Randomized Controlled Trial
Published 2024-11-01“…ObjectiveThis pilot randomized control trial tested preliminary feasibility and effectiveness of the CogXergaming telehealth protocol for improving physical function. MethodsCommunity-dwelling, prefrail older adults were randomly assigned to CogXergaming (n=13) or a control group (n=14). …”
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8259
Organizational and Economic Support for the Integration of Engineering into the Energy Security System of Enterprises on the Basis of Process Approach
Published 2024-09-01“…The paper also considers methods for assessing the economic efficiency of the integration of modern technologies, including cost-benefit analysis, calculation of return on investment and assessment of risk reduction. …”
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8260
ACUTE APPENDICITIS: HISTORY AND CURRENT STATE OF THE MEDICAL CARE
Published 2018-12-01“…Historical-analytical, standard- legal and statistical methods were used. Results. A decrease in the proportion of patients with acute appendicitis in the structure of 7 nosological forms of acute surgical pathology of the abdominal organs, united in the concept of «acute abdomen» (by 64.18 %: from 91.93 % in 1953 to 27.75 % in 2016); a decrease in the number of operated patients by 67.9 %; an increase in operational activity to 98.28 % in 2016; an increase in the proportion of patients with hospitalization for less than 24 hours from 58.13 % (1932-1946) to 66.74 % (1953-2016); the rate of late hospitalization (later than 24 hours) remains almost stable for the entire period of observation (more than 60 years), and in recent years has even a slight increase (+8.21%). …”
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