RACF: A Multimodal Deep Learning Framework for Parkinson’s Disease Diagnosis Using SNP and MRI Data by Jiangbo Cao, Xiaojing Long

“…To address these challenges, this study introduces an innovative multimodal deep learning framework with two primary contributions: (1) a Genome-Wide Association Study (GWAS)-Transformer architecture that autonomously selects single nucleotide polymorphism (SNP) features through GWAS and utilizes a multi-head attention mechanism to model potential associations between non-risk loci, thereby eliminating the reliance on known susceptibility genes; (2) a Residual Attention Contrastive Fusion (RACF) module that tackles the heterogeneity of cross-modal features by dynamically allocating attention weights and applying contrastive loss constraints. …”
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Gut microbiome in gastrointestinal neoplasms: from mechanisms to precision therapeutic strategies by Jiaqian Song, Wei Zhang, Deqiang Wang

“…Future research should integrate multi-omics and AI technologies for dynamic microbial monitoring and modulation, paving the way for microbiome-based precision medicine. …”
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STRONG II trial: stereotactic body radiation therapy following chemotherapy for unresectable perihilar cholangiocarcinoma – a single-arm multicentre phase II study by Derk Jan de Groot, Luisa Vonghia, Bas Groot Koerkamp, Lydi M J W van Driel, Alejandra Méndez Romero, Anne Demols, Erik van Werkhoven, Dirk De Ruysscher, Christelle Bouchart, Marjolein Y V Homs, Joris I Erdmann, Martijn Intven, Ferry Eskens, Harm Westdorp, Timon Vandamme, Suus Y van Loosbroek, Maaike T W Milder, Rianne D W Vaes, Wilhelm den Toom, François Willemssen, Yvette Seppenwoolde, Nadia Haj Mohammad, Joep de Bruijne, Eva Versteijne, Anna M Bruynzeel, Freek Brandts, Pètra M Braam, Eric T T L Tjwa, Akos Gulyban, Jeroen Buijsen, Judith de Vos-Geelen, Maxime Dewulf, Ines Joye, Margriet Dieters, Fred J F Ubbels, Frederik J H Hoogwater, Ben Heijmen

“…Secondary endpoints include toxicity, biliary stent-related events, progression-free survival, OS and QoL using the EuroQoL five-dimensional, five-level (EQ-5D-5L) questionnaire, European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire - Core 30 (QLQ-C30) and the EORTC Biliary Module (QLQ-BIL21). In addition, we will explore the predictive value of the peripheral immunological status (immune-related proteins and serum functional immunological status assay) and its dynamics in determining survival outcomes. …”
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Research progress on immunometabolism and gut microbiota in cryptococcal meningitis: mechanisms and therapeutic implications by Sha Wen, Sha Wen, Sha Wen, Sha Wen, Mu Liu, Mu Liu, Mu Liu, Chengyu Pan, Chengyu Pan, Chengyu Pan, Linhai Zhang, Linhai Zhang, Linhai Zhang, Rong Yan, Rong Yan, Rong Yan, Zucai Xu, Zucai Xu, Zucai Xu

“…Cryptococcal meningitis (CM) is a fatal central nervous system infection caused by Cryptococcus neoformans breaching the blood–brain barrier (BBB), carrying a mortality rate approaching 100% in untreated individuals, while even survivors following treatment often experience neurological complications including optic nerve atrophy, memory impairment, hydrocephalus, and motor dysfunction. …”
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The Ghost of Predator Past: Interaction of Past Predator Exposure and Resource Availability on Toxin Retention and Cell Growth in a Dinoflagellate by Gihong Park, Christina Batoh, Hans G. Dam

“…By contrast, cells directly exposed to predators showed lower growth rates than the other two treatments, and also showed a tradeoff between toxin retention rate and growth rate. …”
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SFRADNet: Object Detection Network with Angle Fine-Tuning Under Feature Matching by Keliang Liu, Yantao Xi, Donglin Jing, Xue Zhang, Mingfei Xu

“…Specifically, within GL²KNet, we construct diverse receptive fields with varying dilation rates to capture features across different spatial coverage ranges. …”
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Thermal, solutal, and radiative oscillatory behavior in vibrating inclined chambers with Non-Darcy porous media by Z.Z. Rashed, Sameh E. Ahmed

“…Furthermore, increasing the frequency of oscillation from 200 to 1000 results in a 41.17 % reduction in the heat transfer rate. In contrast, the considered range of thermal radiation leads to a 44.3 % improvement in the heat transfer rate. …”
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Choroid plexus-mediated CSF secretion remains stable in aging rats via high and age-resistant metabolic activity by Sara D. Lolansen, Eszter O. Révész, Søren N. Andreassen, Marleen Trapp, Chiara Salio, Marco Sassoé-Pognetto, Jens Velde Andersen, Emil W. Westi, Trine L. Toft-Bertelsen, Jonathan H. Wardman, Anne-Kristine Meinild Lundby, Flemming Dela, Annarita Patrizi, Blanca I. Aldana, Nanna MacAulay

“…Here, we resolve age-dependent modulation of CSF dynamics and choroid plexus function by complementary in vivo determinations of intracranial pressure (ICP) and CSF secretion/absorption rates, combined with transcriptomic, morphological, and metabolic analysis of choroid plexus in aging male rats. …”
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Determining kinetics of H2O2 evolution from photoelectrochemical water oxidation by Dongfeng Li, Ruifang Wei, Deyun Zhang, Chenwei Ni, Heng Yin, Lingcong Zhang, Fengtao Fan, Xiuli Wang, Can Li

“…The H2O2 evolution reaction exhibits the same first-hole transfer dynamics as that in O2 evolution reaction. The rate law analysis indicates that H2O2 evolution reaction exhibits the first-order reaction kinetics, demonstrating that the rate-determining step in 2e− water oxidation reaction for H2O2 evolution is the consumption of the first-hole intermediates. …”
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Relationship between peripheral blood miR-146b-5p levels and lymphocyte subsets in patients with sepsis and its predictive value for prognosis: a single-center study by Sha Cheng, Jiaojiao Wang, Pengfei Wang, Xianli Long, Huiling Liu, Xueyin Li, Xiaowei Zhang, Xuemei Zhao, Hang Sun, Chuanxin Wu

“…Survival curves for miR-146b-5p indicated that lower levels of miR-146b-5p (<0.272) were associated with a higher mortality rate (HR 3.063). The absolute counts of lymphocytes (Lym), CD3+ T cells, CD4+ T cells, and CD8+ T cells were significantly lower in the sepsis group compared to the HD group. …”
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Fruit Growth and Oil Accumulation of Olive (<i>Olea europaea</i> L.) Cultivars at Different Locations Along a Latitudinal–Altitudinal Gradient by Leila M. Hamze, María Cecilia Rousseaux, Peter S. Searles, Eduardo R. Trentacoste

“…There are fewer studies concerning how the environment and genotype modulate growth dynamics. Thus, the present study aimed to evaluate the timing of fruit growth, pit hardening, and oil accumulation in several olive cultivars under different air temperatures along a latitudinal gradient (29°–33° S) with a range of altitudes (450–1250 masl) in Western Argentina; determine parameters derived from the dynamics of fruit growth and oil accumulation along the same gradient; and explore possible relationships between derived parameters and air temperatures. …”
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First Real-Time 221.9 Pb/S∙Km Transmission Capability Demonstration Using Commercial 138-Gbaud 400 Gb/S Backbone OTN System over Field-Deployed Seven-Core Fiber Cable with Multiple... by Jian Cui, Yu Deng, Zhuo Liu, Yuxiao Wang, Chen Qiu, Zhi Li, Chao Wu, Bin Hao, Leimin Zhang, Ting Zhang, Bin Wu, Chengxing Zhang, Weiguang Wang, Yong Chen, Kang Li, Feng Gao, Lei Shen, Lei Zhang, Jie Luo, Yan Sun, Qi Wan, Cheng Chang, Bing Yan, Ninglun Gu

“…In this paper, we investigate the real-time long-haul transmission capability of a deployed seven-core MCF cable using commercial 138-Gbaud 400 Gb/s backbone OTN transceivers with a dual-polarization quadrature phase shift keying (DP-QPSK) modulation format. Thanks to the highly noise-tolerant DP-QPSK modulation format enabled by the high baud rate, a real-time 256 Tb/s transmission over a 990.64 km (14 × 70.76 km) deployed seven-core fiber cable with more than 600 fusion splices is field demonstrated for the first time, which achieves a real-time capacity–distance product of 221.9 Pb/s∙km. …”
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Intermittent Blue Light Supplementation Affected Carbohydrate Accumulation and Sugar Metabolism in Red-Light-Grown Tomato Seedlings by Xiangyu Gao, Lingzhi Li, Wenzhong Guo, Yifan Zhai, Xiaoming Wei, Xiaoli Chen

“…According to previous studies, dynamic light regimes might enhance seedling development, survival rates, or economic efficiency in factory-based seedling production systems compared to continuous red and blue light irradiation. …”
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Impacts of Intraseasonal Oscillations on Tropical Cyclone Rapid Intensification in the Northwestern Pacific During Winter by Chaodong Chen, Zheng Ling, Hailun He, Tianyu Zhang

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Channel and Spatial Attention in Chest X-Ray Radiographs: Advancing Person Identification and Verification with Self-Residual Attention Network by Hazem Farah, Akram Bennour, Neesrin Ali Kurdi, Samir Hammami, Mohammed Al-Sarem

“…The attention modules worked by dynamically aggregating feature maps across channel and spatial dimensions to enhance feature differentiation. …”
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Genetic control of organ shape and tissue polarity. by Amelia A Green, J Richard Kennaway, Andrew I Hanna, J Andrew Bangham, Enrico Coen

“…Using the Snapdragon (Antirrhinum) flower as an example, we show how shape development reflects local rates and orientations of tissue growth that vary spatially and temporally to form a dynamic growth field. …”
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Pupillary and microsaccadic responses to cognitive effort and emotional arousal during complex decision making by Krzysztof Krejtz, Justyna Żurawska, Andrew Duchowski, Szymon Wichary

“…Recent empirical evidence also showed that microsaccade characteristics and dynamics can be modulated by mental fatigue and cognitive load (e.g., Dalmaso et al. 2017). …”
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Neuroplasticity Meets Artificial Intelligence: A Hippocampus-Inspired Approach to the Stability–Plasticity Dilemma by Thorsten Rudroff, Oona Rainio, Riku Klén

“…We propose innovative AI designs incorporating dual learning rates, offline consolidation, and dynamic plasticity modulation. …”
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The timing of spontaneous eye blinks in text reading suggests cognitive role by Xander Cornelis, Nicolas Dirix, Louisa Bogaerts

“…The results indicate higher blinking proportions at punctuation marks compared to other positions in the text. Additionally, blink rates were modulated by word frequency and predictability, with higher word frequencies and predictabilities significantly reducing the probability of blinking. …”
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LSCD-Pose: A Feature Point Detection Model for Collaborative Perception in Airports by Ruifeng Meng, Jinlei Wang, Yuanhao Huang, Zhaofeng Xue, Yihao Hu, Biao Li

“…Experiments on real airport datasets representing various apron scenarios demonstrate frame rates up to 461.7 FPS and a 90.5% reduction in model size compared with the baseline. …”
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