The Resuscitation, Equilibrium and De-escalation (RED) strategy: a phased, personalized hemodynamic support in children with sepsis by Jaime Fernández-Sarmiento, Sushitra Ranjit, L. Nelson Sanchez-Pinto, Vinay M. Nadkarni, Roberto Jabornisky, Niranjan Kissoon

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Pulmonary Disease due to Mycobacterium malmoense in British Columbia by Mohamed S Al-Moamary, William Black, Kevin Elwood

“…Cases have, however, rarely been reported from the United States, and, until now, none have been reported in Canada. …”
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Cellular senescence: from homeostasis to pathological implications and therapeutic strategies by Chunhong Li, Yixiao Yuan, YingDong Jia, Qiang Zhou, Qiang Wang, Xiulin Jiang

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Increased risk for alcohol- and other substance-exposed pregnancies among women who smoke tobacco: A secondary analysis of a primary care-based intervention by Thomas F. Northrup, Angela L. Stotts, Stephen M. Fischer, Kirk L. von Sternberg, Mary M. Velasquez

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BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center’s experience by S. S. McThenia, S. S. McThenia, S. S. McThenia, K. M. Reddy, K. M. Reddy, E. Damaraju, E. Castellino, Z. He, R. Beer, F. Chien, F. Chien, F. Chien, R. C. Castellino, R. C. Castellino, R. C. Castellino, A. E. Goldman-Yassen, A. E. Goldman-Yassen, J. R. Fangusaro, J. R. Fangusaro, J. R. Fangusaro, T. MacDonald, T. MacDonald, T. MacDonald

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Investigation of potential Shiga toxin producing Escherichia coli (STEC) associated with a local foodborne outbreak using multidisciplinary approaches by Kristen A. Lozinak, Niketa Jani, Jayanthi Gangiredla, Isha Patel, Christopher A. Elkins, Zonglin Hu, Prince A. Kassim, Robert A. Myers, Pongpan Laksanalamai

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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

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Editorial: Host-diet-microbiome interactions in obesity prevention and treatment by Javad Barouei, Javad Barouei, Mary E. Kable, Mahta Moussavi, Mahta Moussavi, Yu-Hsin Hsieh

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Early and Midterm Outcomes of Percutaneous Arteriovenous Fistula Creation by Ahmed Kamel Abdel Aal, Juri Bassuner, Husameddin El Khudari, Reema F. Alrasheed, Shahroz Aziz, Mohamed Shahin, Ammar Almehmi, Bridget Kowalczyk

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Vaccines for cancer interception in familial adenomatous polyposis by David E. Johnson, Mary L. Disis

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INTERNATIONAL LEGAL FRAMEWORK ON HUMAN TRAFFICKING AND CRIMINAL LIABILITY ON TRAFFICKERS by Paul Nwala

“…Human trafficking, as recognised in the Declaration of the High-level Meeting on the Rule of Law Trafficking in Persons, preys on the vulnerability of victims and can be considered as a premeditated crime. The United Nations Office on Drugs and Crime (UNODC), as guardian of the United Nations Convention against Transnational Organized Crime (UNTOC) and the Protocols thereto, assists States in their efforts to implement the Protocol to Prevent, Suppress and Punish Trafficking in Persons (Trafficking in Persons Protocol). …”
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Factors Leading to Low Utilization of PMTCT Services at Rubaare Health Centre IV in Rubaare Town Council Ntungamo District. by Muhairwe, Robert

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Abuse potential of fentanyl and fentanyl analogues by Anusha Thumma, Kwadwo Mfoafo, Niloofar Babanejad, Alborz Omidian, Yadollah Omidi, Hamid Omidian

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Sodium glucose co-transporter 2 inhibitors (SGLT2i) for pediatric kidney disease: the future is near by Gilda M. Portalatin, Irene Hong-McAtee, Irene Hong-McAtee, Anna M. Burgner, Edward R. Gould, Tracy E. Hunley, Tracy E. Hunley

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Illegal cannabis cultivation in Europe: new developments by David Weinberger, Michel Gandilhon, Jalpa Shah, Nacer Lalam

“…This trend in production must be examined against evolving attitudes towards marihuana at the global level, linked especially to new legislation in the United States and in Canada.…”
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Aduhelm, a novel anti-amyloid monoclonal antibody, for the treatment of Alzheimer’s Disease: A comprehensive review by Hannah W. Haddad, Garett W. Malone, Nicholas J. Comardelle, Arielle E. Degueure, Salomon Poliwoda, Rachel J. Kaye, Kevin S. Murnane, Adam M Kaye, Alan D. Kaye

“…This debilitating disease reportedly consumes 8% of the total United States healthcare expenditure, with medical and nursing outlays accounting for an estimated \$290 billion. …”
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Human-based complex in vitro models: their promise and potential for rare disease therapeutics by Surat Parvatam, Francesca Pistollato, Lindsay J. Marshall, Fabia Furtmann, Devashree Jahagirdar, Mohua Chakraborty Choudhury, Sujata Mohanty, Harshita Mittal, Saveetha Meganathan, Rakesh Mishra

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Synthesis of a Hydroxy-15-Azasterol by Caleb A. H. Jones, Bruce J. Melancon, Craig W. Lindsley

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Duodenal Peptic Ulcer Perforation in the Puerperium Case Report Series by Elizabeth Stiles, Andre Robinson, Erin Fitzgerald, Marie Fleury, Andrew Rubenstein

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A comprehensive method on black-legged tick larvae and nymph feeding on mice to study Lyme disease transmission and acquisition by Aaron Scholl, Bingjie Li, John Dennis, Sandip De

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