Chlorella vulgaris mutants with altered cell walls show increased permeability and enhanced extractability of intracellular molecules by Paolo Canteri, Claudia Battarra, Giulia Mandalà, Francesca Monti, Erika Bellini, Nora Hidasi, Zeno Guardini, Simone Ferrari, Roberto Bassi, Luca Dall’Osto

“…Cell wall also restricts diffusion of organic solvents; thus, limiting the extraction of valuable intracellular compounds. …”
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Experimental Study on Desorption Characteristics of Coalbed Methane under Variable Loading and Temperature in Deep and High Geothermal Mine by Haifeng Ma, Lingjie Wang, Housheng Jia, Jucai Chang, YingMing Li, Xiangyang Zhang, Zuxiang Hu, Zhiqiang Yin

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Evaluation of Preclinical Efficacy of Curcumin-Loaded Bicosome Systems in Amelioration of Oral Mucositis by Daniela Vergara, Claudia Sanhueza, Susana Méndez, Mariela Bustamante, Benjamín Vega, Francisca Acevedo, Olga López

“…Results: The results showed that cur-BS 5× provided sustained release through a mechanism involving both diffusion and matrix relaxation, enhancing curcumin retention in deeper skin layers. …”
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Occurrence, migration, and ecological risk assessment of Neonicotinoid insecticides in water and sediments of Dongting Lake, China by Xiong Mao, Yi Huang, Zhi-tao Huo, Jun Guo, Cong Li, Feng-cun Huang

“…ABSTRACT: Neonicotinoid insecticides (NEOs) have become an integral part of the global insecticide market due to their high efficiency and low toxicity. However, their environmental persistence has raised significant ecological concerns. …”
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A systematic review on machine learning-aided design of engineered biochar for soil and water contaminant removal by Yunpeng Ge, Kaiyang Ying, Guo Yu, Muhammad Ubaid Ali, Abubakr M. Idris, Abubakr M. Idris, Asfandyar Shahab, Habib Ullah, Habib Ullah

“…These instruments expose parameters including nitrogen-to-carbon (N/C) ratios and pyrolysis temperature in adsorption efficiency. The review also covers hybrid methods combining ML with molecular simulations (e.g., DFT) to link mechanistic knowledge with data-driven predictions. …”
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Improvement of Technologies for Isolation and Purification of Biologically Active Substances from Plant Raw Materials by G. N. Turmanidze, V. V. Sorokin, K. S. Stepanov, M. A. Ignatenko

“…During the modernization of equipment for the implementation of new technologies, it is possible to improve its configuration, which makes it possible to significantly increase the yield of active substances at minimal cost. To increase the efficiency of the process of isolating hesperidin from plant materials, we proposed to use a number of technological solutions. …”
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Comparative Morphometric and Histometric Evaluation of Power-Dependent Tissue Ablation Using Fractional Carbon Dioxide Laser by Ryu HG, Park J, Kim H, Kim W, Lee HR, Ko J, Cho SB

“…Linear regression showed strong correlations between energy and ablation depth (r > 0.91) and diameter (r > 0.91), with higher slope coefficients in the 40 W group, indicating greater ablation efficiency.Conclusion: The 40 W fractional CO2 laser system offers enhanced precision, deeper dermal penetration, and reduced thermal diffusion compared with the 30 W, despite delivering equivalent total energy. …”
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Exploring corrosion behavior, antimicrobial evaluation, molecular docking and DFT calculation of thiosemicarbazone ligand and its metal complexes by Howida S. Mandour, Lobna A. Khorshed, Amr M. Abdou, Basma Ghazal

“…The results confirmed that the ligand (HL) acted as a good corrosion inhibitor for copper metal in 1 M HCl solution; as it displayed high percentage of inhibition efficiency about 94.66% and 92.93% after PDP and EIS methods respectively; at its optimum concentration (1 × 10–7 M). …”
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Biomechanics characterization of an implantable ultrathin intracortical electrode through finite element method by Linsen Peng, Longchun Wang, Shuhui Wu, Mingcheng Gu, Shang Deng, Jingquan Liu, Cheng-kung Cheng, Xiaohong Sui

“…., indicating a 50% risk of diffuse axonal injury (DAI), it was recommended to limit the initial step displacement during insertion to 1 μm, increasing to 5 μm at deeper locations (over 500 μm) to balance safety and efficiency. …”
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Dual‐Functional High‐Entropy Polymer Exhibiting Giant Cross‐Energy Couplings at Low Fields by Guanchun Rui, Wenyi Zhu, Li Li, Jongcheol Lee, Yiwen Guo, Qin Zou, Siyu Wu, Ruipeng Li, Thierry Lannuzel, Fabrice Domingues Dos Santos, Mark A. Aubart, Seong H. Kim, Long‐Qing Chen, Lei Zhu, Zi‐Kui Liu, Q. M. Zhang

“…An electrocaloric (EC) polymer capable of generating both large electrocaloric effect (ECE) and substantial electroactuation can enable EC cooling devices to pump heat without external mechanisms, resulting in compact designs and enhanced efficiency. However, achieving both high ECE and significant electroactuation remains challenging. …”
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Ionic‐electronic dual‐conductor interface engineering and architecture design in layered lithium‐rich manganese‐based oxides by Youyou Fang, Yuefeng Su, Jinyang Dong, Jiayu Zhao, Haoyu Wang, Ning Li, Yun Lu, Yujia Wu, Wenbo Li, Ni Yang, Xiaojuan Wu, Feng Wu, Lai Chen

“…Despite their inherent advantages, these materials encounter significant practical hurdles, including low initial Coulombic efficiency (ICE), diminished cycle/rate performance, and voltage fading during cycling, hindering their widespread adoption. …”
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Hyaluronidases improve the hyaluronic acid yield during the fermentation of Streptococcus zooepidemicus by Chuan-Li Kang, Chuan-Li Kang, Chuan-Li Kang, De-Qiang Zheng, De-Qiang Zheng, De-Qiang Zheng, Zhi-Yuan Yao, Kang Yang, Yuxue Zhao, Zihan Mao, Yang Liu, Haijun Li, Jin-Song Gong, Lei Liu, Qingwen Jia, Qingwen Jia, Zheng-Hong Xu, Zheng-Hong Xu, Jin-Song Shi, Le Xue

“…However, the accumulation of high-molecular-weight (HMW) HA increases broth viscosity, impeding nutrient diffusion and limiting yield.MethodsTo address this, four HAases, HHya1, LHya2, SHya3, and EHya4, were expressed and screened for enzymatic activity. we evaluated the strategic addition of hyaluronidases (HAases) to degrade HMW HA during fermentation, thereby reducing viscosity and enhancing productivity.ResultsHHya1 and EHya4 exhibited superior expression levels and catalytic efficiency. …”
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Amide proton transfer-weighted imaging and T1 mapping as diagnostic tools to evaluate high-risk histopathologic phenotypes before surgery in rectal adenocarcinoma and their correla... by Yaxin Chai, Yaxin Chai, Yongchao Niu, Ruixue Cheng, Pan Liang, Jianbo Gao

“…The measured parameters included APT signal intensity (APT SI), T1 relaxation time before (native T1) and after (post-contrast T1) enhancement, and apparent diffusion coefficient (ADC). The receiver operating characteristic (ROC) curve was used to evaluate diagnostic efficiency, and Spearman correlation analysis was used to evaluate the correlation between parameters with Ki-67, respectively.ResultsAPT SI values were significantly different between the mucinous adenocarcinoma (MC) group and the common adenocarcinoma (AC) group in two centers (center 1: [2.64 ± 0.33%] vs. [2.22 ± 0.78%], P<0.05), (center 2: [3.27 ± 0.80%] vs. [2.59 ± 0.77%], P<0.05). …”
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Impact of CO2-water-coal on enhanced coalbed methane recovery by CO2 injection in Huainan coalfield by Helong ZHANG, Shiqi LIU, Yuchen TIAN, Wenkai WANG, Shuxun SANG, Sijian ZHENG, Bing LI, Yongchun CHEN

“…The permeability recovery further facilitated pressure transmission, CO2 adsorption, and CH4 desorption/diffusion, ultimately enhancing CH4 production and CO2 sequestration efficiency.…”
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Self-propelled gas nanomotor-integrated microneedles for melanoma therapy: Dual-action in situ eradication and metastatic suppression by Chungchi Lee, Shanghui Huang, Huiling Liu, Xinyue He, Yifan Hao, Lizhi Zeng, Yuhan Li, Zijin Lv, Yiyang Xu, Rui Guo

“…Traditional treatments like excision, chemotherapy, and immunotherapy often fail due to their invasiveness, toxicity, and poor drug delivery efficiency caused by skin barriers. Microneedles (MNs) offer a minimally invasive alternative, directly penetrating the skin to deliver drugs to tumor sites while minimizing side effects. …”
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The presence of substrate warrants oxygen access tunnels toward the catalytic site of lipoxygenases by Thiliban Manivarma, Wieslaw Nowak, Yulia Y. Tyurina, Vladimir A. Tyurin, Hülya Bayir, Valerian E. Kagan, Karolina Mikulska-Ruminska

“…The molecular oxygen required for this catalytic reaction is subject to continuous competition among various oxygen-consuming enzymes, which influences the efficiency of lipid peroxidation. In this study, we utilized structure-based modeling and all-atom molecular dynamics simulations to explore the oxygen diffusion pathways in 15LOX-1 under varying oxygen concentrations and in the presence of key components, including a substrate, binding partner PE-binding protein 1 (PEBP1), and the membrane environment. …”
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CPFD Simulation of Operation Characteristics of a 10t/d Sludge and Biomass Co-incineration Fluidized Bed Reactor by REN Shaohui, YU Qiao, LIN Li, XIANG Jiatao, MA Lun, ZHANG Shihong

“…Dolomite demonstrated limited in-situ desulfurization (SO₂↓0.01% vs. quartz's 0.02%) through CaO sulfation, though reaction efficiency was hindered by poor gas-solid contact—SO₂concentrated near the outlet where bed material presence diminished. …”
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Naringenin-Loaded Solid Lipid Nanoparticles: Physical–Chemical Characterization and In Vitro Antibacterial Activity by Federica De Gaetano, Francesco Caridi, Noemi Totaro, Consuelo Celesti, Valentina Venuti, Giovanna Ginestra, Antonia Nostro, Silvana Tommasini, Cinzia Anna Ventura, Rosanna Stancanelli

“…NRG-SLNs systems were prepared by a solvent emulsification/diffusion and ultrasonication method, using Compritol^® 888 ATO (COM) as the lipid. …”
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Cobalt (II) phthalocyanine derived Co3O4@HCNFs as highly effective bifunctional electrocatalysts for iodide redox couple reduction (IRR) and oxygen reduction reaction (ORR) by Ziyu Guo, Wenyu Gong, Jianing Guo, Mingxing Wu

“…Herein, nitrogen-enriched hollow carbon nanofibers with opens at both ends (HCNFs) are first synthesized, which show decent catalytic activity for the IRR, and a power conversion efficiency (PCE) of 6.95 % is achieved by the corresponding DSCs. …”
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Brain topology and cognitive outcomes after cardiac arrest: A graph theoretical analysis of fMRI data by Marlous M.L.H. Verhulst, Puck Lange, Anil Man Tuladhar, Prejaas Tewarie, Pauline C.W. van Gils, Caroline van Heugten, Judith Bonnes, Thijs Delnoij, Rick Helmich, Jeannette Hofmeijer

“…Since postanoxic encephalopathy is diffuse, measures of global network organization might contribute to identifying these patients at risk. …”
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