Engineering of SauriCas9 with enhanced specificity by Xiaoqi Zhang, Chen Tao, Miaomiao Li, Sufang Zhang, Puping Liang, Yan Huang, Huihui Liu, Yongming Wang

“…Our results demonstrated that the most efficient single-guide RNAs for SauriCas9-R253A exhibited comparable activity to SpCas9 and showed no detectable off-target effects in the disruption of these genes, highlighting its therapeutic potential.…”
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The impact of working capital management on the business performance: Evidence from food and beverage firms listed on the Vietnamese stock market by Nguyễn Thị Như Quỳnh, Trần Như Quỳnh

“…By utilizing the Feasible Generalized Least Squares (FGLS) regression model and using data from 44 F&B enterprises listed on HOSE and HNX, covering the period from 2017 to 2022, the research results indicate that certain independent variables such as Inventory Conversion Period (ICP), Receivables Conversion Period (RCP), Payable Deferral Period (PDP), and Cash Conversion Cycle (CCC) exhibit adverse effects on the dependent variable, Return On Assets (ROA). …”
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Research progress and application prospects of flexible wearable sensor in spacesuit by Aiming Bu, Wanxin Zhang, Qian Ran, Dongyue Liu, Jialu Ma, Rongqing Wang, Kun Shang, Hongrui Yang, Zhiqiang Mei

“…The wearable sensors have drawn more and more attention because its operations are simple and real-time detections are available. It can realize the benefits of heart rate, breathing, sweat, action recognition and date acquisition, etc. …”
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Fine-grained vehicle recognition under low light conditions using EfficientNet and image enhancement on LiDAR point cloud data by Guanqiang Ruan, Tao Hu, Chenglin Ding, Kuo Yang, Fanhao Kong, Jinrun Cheng, Rong Yan

“…Abstract The detection and recognition of vehicles are crucial components of environmental perception in autonomous driving. …”
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Axion-like relics: new constraints from old comagnetometer data by Itay M. Bloch, Yonit Hochberg, Eric Kuflik, Tomer Volansky

“…An ultra-light relic axion-like particle can source an anomalous field that permeates space, allowing for its detection by comagnetometers. Here we derive new constraints on relic axion-like particles interaction with neutrons and electrons from old comagnetometer data. …”
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Irritable Bowel Syndrome Diagnosis: Should There Be Alertness to Cancer? by A. A. Sheptulin, N. L. Jahaya, A. V. Sedova

“…In this case, colonoscopy for suspected IBS is performed only in patients aged over 50 years old, provided a hereditary predisposition to CRC and the “alarm symptoms” are detected. It has been recently shown that CRC can proceed under the “mask” of IBS. …”
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Bowel diseases and constipation in practice of the obstetrician and gynecologist by I. V. Kuznetsova, Yu. B. Uspenskaya

“…At constipated female patients detection of intestinal dysfunction etiology and improvement of management, it is necessary to pay attention not only to gastroenterological symptoms, but also to possible relation of symptoms to menstrual cycle, reproductive status and gynecologic pathology. …”
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Difficulties of iron-deficiency anemia diagnostics by I. V. Mayev, D. T. Dicheva, D. N. Andreyev, Yu. S. Subbotina

“…To illustrate difficulties of detection of sources of gastro-intestinal bleeding (GIB) at investigation of patient with severe chronic iron-deficiency anemia.Key points. …”
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Effects of enhanced fermentation with high-yielding strains of Tetramethylpyrazine on flavor quality of Douchiba by Panpan Yang, Qin Wang, Yurou Yang, Anyan Wen, Haiying Zeng, Na Liu, Likang Qin

“…Furthermore, the concentrations of taste substances, organic acids, free amino acids, and free fatty acids in MG were significantly increased. 87 flavor compounds were detected by gas chromatography-ion mobility spectrometry. …”
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Experience of enrollment and management of the Waiting list for liver transplantation at hepatological center by Ye. N. Bessonova, O. A. Stroganova, Yu. A. Glazyrina, I. A. Kornilova

“…Development and management of the Waiting list for liver transplantation is a complex, multiplane task and requires careful, complex and very versatile investigation of the patient before surgery, dynamic rating of severity of status and urgency class of operation performance, duly while maximally effective detection and treatment of accompanying diseases.…”
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Simulating human behavior under earthquake early warning by Matthew Wood, Sara K. McBride, Xilei Zhao, Dare Baldwin, Elizabeth S. Cochran, Xiaojian Zhang, Nicolas Luco, Ruggiero Lovreglio, Tom Cova

“…Recent advances in earthquake detection have resulted in the development of earthquake early warning (EEW) systems. …”
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Determining Bandgap of Thermochromic Phosphor Films via Reflectance Measurements under Controlled Heating. by Rwabona, Katashaya Steven

“…The reflected light is detected using a calibrated photodiode circuit based on an operational transconductance amplifier. …”
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Determining Bandgap of Thermochromic Phosphor Films via Reflectance Measurements under Controlled Heating by Katashaya, Steven Rwabona

“…The reflected light is detected using a calibrated photodiode circuit based on an operational transconductance amplifier. …”
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The Opportunity of Using Diode Laser with the Length of 1940 nm in the Treatment of Hemorrhoids by S. A. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, O. A. Mainovskaya, Yu. L. Trubacheva, O. Yu. Fomenko, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. M. Battalova, E. M. Bogdanova

“…According to sphincterometry, no violations of anal retention function were detected in all 28 patients.Conclusion. Surgical treatment of hemorrhoids of the 2nd and 3rd stages with the use of a diode laser with a wavelength of 1940 nm. with proper technical performance and the choice of optimal energy, it allows to achieve a good clinical effect. …”
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MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. …”
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Preference for HIV testing among community residents in Yunnan Province, China: results from a discrete choice experiment by Jingwen Yang, Chenquan Qiu, Renhai Tang, Wenbin Dong, Enlong Yao, Huyunzhao Wang, Shuwen Lin, Minyang Xiao, Zuyang Zhang, Jin Niu, Liru Fu, Lijun Song, Xuehua Li, Yuhua Shi, Xiaowen Wang

“…Abstract Background The detection and early identification of people living with HIV/AIDS (PLWH) and their rapid engagement in antiretroviral treatment are indispensable for fighting HIV transmission. …”
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Prucalopride in treatment of functional chronic constipation by A. A. Sheptulin

“…Numerous studies confirmed that on a background of prucalopride intake in a dose of 2 or 4 mg for 4-12 wks in patients with chronic constipation defecation frequency increases and quality of life improves. …”
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UV-induced reorganization of 3D genome mediates DNA damage response by Veysel Oğulcan Kaya, Ogün Adebali

“…We show that adaptive reorganization of the 3D genome is a key mediator of the damage response, providing new insights into the complex interplay of genomic structure and cellular defense mechanisms against UV-induced damage, thereby advancing our understanding of cellular resilience.…”
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An automatic pipeline for temporal monitoring of radiotherapy-induced toxicities in head and neck cancer patients by Parsa Bagherzadeh, Khalil Sultanem, Gerald Batist, Shirin Abbasinejad Enger

“…Two tasks of toxicity mention detection and toxicity extraction were defined. Pre-trained language models such as BERT, Clinical BioBERT, and Clinical Longformer were fine-tuned. …”
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