Targeting USP42 induces DNA damage and inhibits cell growth in prostate cancer by Yinghao Zhou, Chenchen Chen, Yibo Meng, Jianchao Ge, Shengkui Meng, Xillong Wang, Yaozong Xu, Guowei Shi, Wandong Yu, Xuetao Hu, Jun Zhang

“…During its progression, deubiquitination-mediated alterations in biological processes play critical roles in tumor metabolism, stem cell characteristics, immune evasion, DNA damage repair, and chemoresistance. …”
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High-Voltage High-Capacity Active Filter Technology for High Voltage DC Converter Station by WANG Ling, MA Weimin, JI Yiming, LI Ming, WU Fangjie, XU Ying, DU Xiaolei, ZHANG Xiujuan

“…This technology would solve the inherent defects of traditional passive filters and enable adaptation to the fluctuations in the current AC power grid. …”
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Psychosocial factors of psychological maladaptation in female patients of a cosmetology clinic by E. S. Bagnenko

“…In the field of aesthetic medicine, there is a lack of psychological research despite the obvious impact of cosmetic defects on the emotional state and social functioning of a person. …”
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Research review and innovative analysis of UAV pipeline inspection based on knowledge graphs by Yinghan MA, Hong ZHAO

“…Objective In the energy sector, pipeline inspection and monitoring provide an efficient method for detecting and addressing defects in energy pipeline transportation at an early stage, thereby ensuring the safe operation and sustainable development of pipeline systems. …”
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Evaluation of the Effectiveness of the National Vision Screening Program in School-Age Children by Mehtap Savar Çağlayan, Betül Dertsiz Kozan

“…Objective: Visual defects are common in school-age children and are one of the factors that negatively affect school success. …”
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Mechanical Design of a Novel Functionally Graded Lattice Structure for Long Bone Scaffolds by Fabio Distefano, Gabriella Epasto, Mahsa Zojaji, Heidi-Lynn Ploeg

“…The implantation of porous scaffolds is essential for treating large bone defects and must mimic natural bone’s geometric and mechanical behaviour. …”
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Mechanical properties and mechanism of damage and deterioration of coal under cyclic loading by Ziwei Ding, Qingbao Tang, Xinwei Gong, Jindui Jia, Guangqing Di, Long Chen

“…Abstract To analyze the mechanical characteristics of damaged coal bodies and the mechanisms of evolution and degradation of internal pore and fracture defects under cyclic loads, raw coal containing original pore and fracture materials was selected as the research material. …”
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Predictive Value of Tissue-induced Oxidative Stress on Urogynecology Synthetic Graft Reinforcement: An Experimental Animal Study by Potic Milan, Ignjatovic Ivan, Vuckovic Bojan

“…Methods: Electron microscopic analysis of six different grafts, all with Polypropylene as their major component, was performed to determine the primary mesh characteristics. Full-thickness abdominal wall defects were repaired using monofilament, multifilament, and coated grafts in male Wistar rats. …”
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Fixator-Assisted Nailing for Femur Neck Fracture Nonunion: A Case Series Study by Majdi Hashem, Mohammad S. Al-Tuwaijri

“…The conditions that were excluded from this study included hip joints with preexisting osteoarthritis, radiographic evidence of avascular necrosis of the femoral head, and associated ipsilateral acetabulum fracture or fracture-dislocation. The fracture characteristics that were selected for the fixator-assisted nailing (FAN) technique were clear signs of pseudoarthrosis (such as sclerosis, clear fracture line defects, and failure of implants), in addition to evidence of varus malalignment. …”
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Physicochemical Properties of Demineralized Bone Matrix and Calcium Hydroxide Composites Used as Bone Graft Material by Octarina, Florencia Livia Kurniawan, Firda Amalia Larosa, Olivia Nauli Komala, Meircurius Dwi Condro Surboyo

“…Vertical bone defects can result in alveolar bone resorption, which may be addressed using composite grafts. …”
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Effects of mechanical vibrations on chondrocytes in monolayer culture for regenerative cartilage by Yura WATANABE, Toshihiko SHIRAISHI

“…This suggests that the 25 Hz and 0.5 G mechanical vibration is beneficial for cultured cartilage transplantation in a simple procedure, providing the cultured cartilage with more hyaline cartilage characteristics, higher adhesion to cartilage defects, and greater strength than in the static state. …”
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Rotary Panoramic and Full-Depth-of-Field Imaging System for Pipeline Inspection by Qiang Xing, Xueqin Zhao, Kun Song, Jiawen Jiang, Xinhao Wang, Yuanyuan Huang, Haodong Wei

“…This system provides an adaptive imaging solution for detecting defects on the inner surfaces of irregular pipelines, offering significant potential for practical applications in pipeline inspection and maintenance.…”
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Predictability of a New Orthodontic Extrusion Technique for Implant Site Development: A Retrospective Consecutive Case-Series Study by E. Conserva, M. Fadda, V. Ferrari, U. Consolo

“…In clinical daily practice, there are situations in which implant sites have vertical and/or horizontal bone defects and often we must improve their morphology and dimensions before fixture insertion. …”
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MIL-53(Fe)-Glucose self-assembled complex for enhanced angiogenesis and endothelial tip cell activation by Jie Wu, Leyi Liu, Runze Li, Kuangwu Pan, Duoling Xu, Chao Wang, Yuhao Liu, Chao Wang, Yi He, Weijie Zhuang, Kechen Li, Wei Zhao, Dongsheng Yu

“…Abstract Critical bone defects continue to pose a critical challenge in clinical settings. …”
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Immune checkpoint inhibitor outcomes and prognostic factors in gynecologic tract melanoma: a single-center analysis by Jianzhang Wang, Kemin Li, Kemin Li, Rui Li, Rui Li, Jing Zeng, Jing Zeng, Rutie Yin, Rutie Yin

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Cervical Stump Cancer after Subtotal Hysterectomy: A Retrospective Research of 127 Cases from China and Literature Review by Jia Wang, Xi Zeng, Lin Min, Lin Li

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Mesoscale mechanisms of the diffuse dielectric behaviour and retention of the polar nano-regions in the polycrystalline ferroelectric BaTiO3 by Lyubov Gimadeeva, Andrei Ushakov, Alexey Pugachev, Anton Turygin, Ruiyi Jing, Qingyuan Hu, Xiaoyong Wei, Zimeng Hu, Vladimir Shur, Li Jin, Denis Alikin

“…Our findings reveal that retention of the polar phase regions is driven by the charged defects, which act as the origin of the spatially non-uniform internal electric fields. …”
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Recurrent cellulitis associated with lymphoedema in Noonan syndrome: case reports with RIT1 variants and literature review by Yuki Kobayashi, Takeya Adachi, Umi Tahara, Moemi Tanaka, Hiroki Arakawa, Yohei Funatsu, Kazunori Moritani, Mamiko Yamada, Kenjiro Kosaki, Toyoko Inazumi

“…Abstract Noonan syndrome (NS) is a RASopathy, a disorder caused by genetic alterations involving the Ras/mitogen-activated protein kinase pathway. It causes characteristic clinical manifestations, including facial dysmorphism and congenital cardiac defects. …”
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine by Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu

“…Researchers have induced neural organoids with regional characteristics by mimicking morphogen gradients in neural development. …”
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Solvent-free fabrication of ultrathin two-dimensional metal oxides/sulfides in a fixed interlayer by geometric confinement by Weixue Wang, Yang Liu, Xinjie Du, Huihui Wang, Yuejie Ai, Qianwei Liu, Xiangke Wang, Zhe Chen

“…Abstract Two-dimensional (2D) nanomaterials display unique characteristics owing to their ultrahigh surface-to-volume ratio and quantum confinement effects. …”
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