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Glutathione: A Key Regulator of Extracellular Matrix and Cell Death in Intervertebral Disc Degeneration
Published 2024-01-01“…Intervertebral disc degeneration (IVDD) is a degenerative disease accompanied by the loss of nucleus pulposus cells and the degradation of extracellular matrix (ECM), which tends to be associated with lower back pain. …”
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The critical role of TRIM protein family in intervertebral disc degeneration: mechanistic insights and therapeutic perspectives
Published 2025-02-01Subjects: “…intervertebral disc degeneration (IVDD)…”
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What Remains to Be Discovered?
Published 2021-10-01“…It seems that what may never be discovered is scientific evidence of life after death. …”
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DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma
Published 2025-01-01“…Sustained overexpression of ACADS not only suppressed the proliferation, migration, and invasion of HCC cells but also promoted immunogenic cell death (ICD) via the upregulation of calreticulin. …”
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Factors of progression to severity and death in COVID-19 patients at two health care sites in Bamako, Mali
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An ivory statuette depicting the god Thanatos discovered near Tomis (Moesia Inferior)
Published 2025-01-01“…The closest analogy for our representation comes from Northern France, where a small bronze statue was discovered in a villa rustica in Salouël, a commune located on the outskirts of Amiens. …”
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Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets
Published 2025-01-01“…Melanoma cells often resisted cell death mechanisms, maintaining their growth by inhibiting apoptosis and evading autophagic cell death. …”
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Analysis of a Family with Brugada Syndrome and Sudden Cardiac Death Caused by a Novel Mutation of SCN5A
Published 2022-01-01“…The clinical features include ventricular fibrillation, syncope, and sudden cardiac death. A family with Brugada syndrome with sudden cardiac death was analyzed to locate the associated mutation in the SCN5A gene. …”
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The mutational spectrum of NRAS gene discovers a novel frameshift mutation (E49R) in Saudi colorectal cancer patients
Published 2025-01-01“…Abstract Colorectal cancer (CRC) is a major health problem the world face currently and one of the leading causes of death worldwide. CRC is genetically heterogeneous and multiple genetic aberrations may appear on course of the disease throughout patient’s lifetime. …”
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mtSTAT3 suppresses rheumatoid arthritis by regulating Th17 and synovial fibroblast inflammatory cell death with IL-17-mediated autophagy dysfunction
Published 2025-01-01“…We first discovered that IL-17 increased the accumulation of abnormal autophagosomes and the expression of inflammatory cell death factors in synovial fibroblasts and decreased mitoSTAT3 activation. …”
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Dwelling in the Abyss: Society in Werner Herzog and Martin Heidegger
Published 2025-02-01“…In the light of Heidegger’s ideas of dwelling, thrownness, they-self, authenticity, abyss and being-towards-death, I look into the abyss of society as represented by Herzog, considering dwelling with humans in The Enigma of Kaspar Hauser (1974) and Into the Abyss (2011) as dwelling through language and dwelling in proximity to death. …”
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Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
Published 2025-01-01“…Furthermore, it was discovered that quercetin increased the percentage of dead cells and cell cycle arrests in the S and G2/M phases. …”
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Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein
Published 2016-01-01“…CD95 is one of the best studied members of the death receptor family. Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC). …”
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Unraveling Ferroptosis: A New Frontier in Combating Renal Fibrosis and CKD Progression
Published 2024-12-01“…Ferroptosis is a type of discovered an iron-dependent lipid peroxidation-regulated cell death. …”
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K-1 Yongquan & Talahridaya points: A key to change the course of cardiopulmonary resuscitation (CPR) rescues
Published 2024-12-01“…Inchauspe has consistently continued such unique research recovering impending death situation victims in the most varied scenarios. …”
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