Showing 161 - 180 results of 1,777 for search 'Damage programs', query time: 0.16s Refine Results
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    In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage by Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang

    Published 2025-08-01
    “…Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered by neuro‐glial units for persistent neuroinflammation, oxidative damage and programmed neuronal cell death. Single‐target and traditional multi‐target therapies, derived from individual drugs, show limited efficacy in addressing these interconnected events, due to spatiotemporal heterogeneity of action in single‐target components. …”
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    Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade by Simon Smith, Hormas Ghadially, Kevin J Harrington, Alan A Melcher, Isla Leslie, Eva Crespo-Rodriguez, Galabina Bozhanova, Emmanuel C Patin, Harriet Whittock, Martin McLaughlin, Malin Pedersen, James Harper, Pablo Nenclares, Heba Soliman, Magnus T Dillon, Lorna Grove, Davina Northcote, Holly Baldock, Gabriella Baker, Joan Kyula, Jeane Guevara

    Published 2022-03-01
    “…The benefit of immunotherapies based on T cell immunoreceptor with Ig and ITIM domains (TIGIT) and Programmed cell death protein 1 (PD-1) immune checkpoint blockade following ATRi/RT treatment was assessed in the MOC2 model and confirmed in another HPV-negative murine oral squamous cell carcinoma model called SCC7. …”
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    MS CETSA deep functional proteomics uncovers DNA repair programs leading to gemcitabine resistance by Ying Yu Liang, Khalidah Khalid, Hai Van Le, Hui Min Vivian Teo, Mindaugas Raitelaitis, Marc-Antoine Gerault, Jane Jia Hui Lee, Jiawen Lyu, Allison Chan, Anand Devaprasath Jeyasekharan, Wai Leong Tam, Pär Nordlund, Nayana Prabhu

    Published 2025-05-01
    “…Initial responses in both, gemcitabine resistant and sensitive cells, reflect known targeted effects by gemcitabine on ribonucleotide reductase and DNA damage responses. However, later responses diverge dramatically where sensitive cells show induction of characteristic CETSA signals for early apoptosis, while resistant cells reveal biochemical modulations reflecting transition through a distinct DNA-damage signaling state, including opening of cell cycle checkpoints and induction of translesion DNA synthesis programs, allowing bypass of damaged DNA-adducts. …”
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  15. 175

    Assessing the effectiveness of air pollution control programs in Tehran using air quality trend analysis by Zohreh Khorasanian, Naghmeh Mobarghaee Dinan, Saeed Soufizadeh, Reihaneh Rasoolzadeh

    Published 2019-03-01
    “…Undoubtedly, one of the most important ways to reduce environmental pollution is the use of control programs and measures. Therefore, this study aims to evaluate the effectiveness of some plans and programs to reduce the air pollution of a metropolis (Tehran). …”
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  16. 176

    The impact of a disaster medicine clinical training program on medical students’ disaster literacy by Aysel Başer, Zeynep Sofuoğlu

    Published 2025-01-01
    “…Result The DLS scores of the experimental group showed significant improvement after the training program compared to their pretest scores (Total Scale: p < 0.001, Damage Mitigation: p = 0.002, Preparation: p < 0.001, Response: p < 0.001, and Relief: p = 0.004). …”
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    Organizational Management Of The Arabic Language Course Program At Boarding School Al Hidayah Batu by M. syihabul Ihsan Al Haqiqy, Aminudin, Destia Harsita, Afifah Anjaina Widodo, Danial Hilmi

    Published 2024-04-01
    “…This study aims to describe the organizational management in the Arabic language course program at Pondok Pesantren Al-Hidayah Batu. This research uses qualitative research methods, case study type. …”
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    Cell cycle regulation and cytoskeletal remodelling are critical processes in the nutritional programming of embryonic development. by Angelina Swali, Sarah McMullen, Helen Hayes, Lorraine Gambling, Harry J McArdle, Simon C Langley-Evans

    Published 2011-01-01
    “…While these describe processes leading from nutritional insult to development of the actual pathology, the initial underlying cause of the programming effect remains elusive. To establish the primary drivers of programming, this study aimed to capture embryonic gene and protein changes in the whole embryo at the time of nutritional insult rather than downstream phenotypic effects. …”
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