Post-sepsis chronic muscle weakness can be prevented by pharmacological protection of mitochondria by Meagan S. Kingren, Alexander R. Keeble, Alyson M. Galvan-Lara, Jodi M. Ogle, Zoltán Ungvári, Daret K. St Clair, Timothy A. Butterfield, Allison M. Owen, Christopher S. Fry, Samir P. Patel, Hiroshi Saito

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Analisis Kandungan Logam Berat Tembaga (Cu) pada Kepiting Bakau (Scylla sp.) di Sungai Wonorejo, Surabaya <br><i>[Analysis of Heavy Metal Copper (Cu) Content on Mud Crab (Scylla s... by Boedi Setya Rahardja, Adriana Monica Sahidu, Fani Fariedah

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Mechanisms by which statins protect endothelial cells from radiation-induced injury in the carotid artery by Karima Ait-Aissa, Karima Ait-Aissa, Linette N. Leng, Nathanial R. Lindsey, Xutong Guo, Denise Juhr, Olha M. Koval, Isabella M. Grumbach, Isabella M. Grumbach, Isabella M. Grumbach

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Clinical evaluation of oxidative stress in patients with diabetes mellitus type II: Impact of acute exercise by Kostić Nada, Čaparević Zorica, Marina Đorđe, Ilić Sanja, Radojković Jana, Ćosić Zoran, Bakić-Ćelić Vera

“…We suggest that it could be a compensatory mechanism to preventing free radicals tissue damage. We hypothesize that a physical training program induces an enhance of muscular and liver antioxidant enzymes activity and reduces oxidative stress. …”
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ATYPICAL HEMOLYTIC UREMIC SYNDROME DIAGNOSIS AND TREATMENT by Atakan Turgutkaya

“…All patients receiving complement inhibitors should be included in the vaccination program for Neisseria meningitis, Streptococcus pneumonia, and Haemophilus influenza type b, and early signs of infection should be carefully monitored and necessary parenteral antibiotic therapy should be started without delay. …”
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A cell wall-targeting urease-derived peptide as a potential antifungal agent against Candida species by Ana Paula A. Perin, Julia C.V. Reuwsaat, Heryk Motta, Fernanda Cortez Lopes, Matheus V.C. Grahl, Andrea G. Tavanti, Marilene H. Vainstein, Charley C. Staats, Célia R. Carlini, Rodrigo Ligabue-Braun, Lívia Kmetzsch

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Molecular and immune landscape of tumours in geriatric patients with non-small cell lung cancer, melanoma and renal cell carcinoma by Abdul Rafeh Naqash, April K Salama, Emil Lou, Andrew Elliott, Wafik S El-Deiry, Chul Kim, Stephen V Liu, Anwaar Saeed, Hirva Mamdani, Khalil Choucair, Dipesh Uprety, Phillip Walker, Himisha Beltran, Matthew James Oberley, Azhar Saeed, Lujia Chen

“…Then, using next-generation sequencing and programmed death-ligand 1 (PD-L1) assessment, we evaluated gene expression differences between age groups and across tumour types, with a focus on ageing-related processes such as DNA damage response (DDR), immune checkpoint (IC) and metabolism-related genes. …”
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Neuroinflammation and Natural Antidepressants: Balancing Fire with Flora by Ana Clara Figueiredo Godoy, Fernanda Fortes Frota, Larissa Parreira Araújo, Vitor E. Valenti, Eliana de Souza Bastos Mazuqueli Pereira, Claudia Rucco P. Detregiachi, Cristiano M. Galhardi, Flávia Cristina Caracio, Rafael S. A. Haber, Lucas Fornari Laurindo, Masaru Tanaka, Sandra M. Barbalho

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Practitioner perspectives on informing decisions in One Health sectors with predictive models by Kim M. Pepin, Keith Carlisle, Richard B. Chipman, Dana Cole, Dean P. Anderson, Michael G. Baker, Jackie Benschop, Michael Bunce, Rachelle N. Binny, Nigel French, Suzie Greenhalgh, Dion RJ O’Neale, Scott McDougall, Fraser J. Morgan, Petra Muellner, Emil Murphy, Michael J. Plank, Daniel M. Tompkins, David TS Hayman

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Effects of particulate air pollution exposure on lung-brain axis and related miRNAs modulation in mouse models by Alessandro Giammona, Alessandro Giammona, Giulia Terribile, Giulia Terribile, Giulia Terribile, Paolo Rainone, Paolo Rainone, Chiara Pellizzer, Danilo Porro, Antonio Cerasa, Giulio Sancini, Giulio Sancini, Giulio Sancini, Ameen-Ur Rashid, Ameen-Ur Rashid, Sara Belloli, Sara Belloli, Sara Belloli, Silvia Valtorta, Silvia Valtorta, Silvia Valtorta, Alessia Lo Dico, Alessia Lo Dico, Gloria Bertoli, Gloria Bertoli

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Large-scale genomic deletion in spl39 activates immune responses and confers resistance to rice bacterial blight by Cheng Fang, Wei Ma, Xiaotong Zhu, Xiaotong Zhu, Lingling Peng, Lingling Peng, Liangzhi Tao, Zhiqiang Zhao, Fengbin Wang, Yafeng Ye, Bojun Ma, Yuejin Wu, Jie Yuan, Binmei Liu, Xifeng Chen, Weimin Cheng

“…Lesion mimic mutants (LMMs) are invaluable for uncovering the molecular mechanisms of programmed cell death (PCD) and plant immunity and identifying more LMMs expands our understanding of these complex processes. …”
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Defining acceptance criteria for silver nanoparticles: correlating synthesis quality with biological outcomes in an In Vitro Lung Cancer Model by Bárbara Gomes, Marjorie Dardis Murucci, Wanderson de Souza, Beatriz Kopke Dal-Cheri, Ana Resende, Natália Yoshihara, Luths Geaquinto, José Mauro Granjeiro, Celso Sant'Anna, Leonardo Boldrini

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Factors Affecting the Agricultural Sustainability of Wheat Farms in Kermanshah County by Reza Movahedi, Nafiseh Amiribavandpour, Karim Naderi Mahdeei

“…1- Introduction Inappropriate use of pesticides and fertilizers in Iran has led to severe damages on soil and water resources; reducing the fertility and performance of the lands, environmental contamination, and damages to the ecological cycle of nature and health problems for humans, animals and the environment. …”
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Evaluation of bio-efficacy of Metarhizium anisopliae against the pink bollworm Pectinophora gossypiella (Saunders), with insights into its colonization potential and insecticide co... by Snehal Thavkar, Shivaji Thube, Pramod Panchbhai, Nandkishor Lavhe, Tinni Pillai, Vivek Shah, Vrushali Deshmukh, Thavaprakasa R. Pandian, Babasaheb Fand, Prabhulinga Tenguri, Akash Nikoshe, Mhatre Priyank, Gajanan Behere, Yenumula Prasad

“…This strain can be integrated into PBW management programs with chemical insecticides, improving pest control and lessening environmental impact.…”
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Prognostic Impact of Stimulator of Interferon Genes Expression in Triple Negative Breast Cancer by Tetsuyo Maeda, Makiko Ono, Tomo Osako, Tomohiro Chiba, Satoko Baba, Asumi Iesato, Yukinori Ozaki, Yuka Inoue, Natsue Uehiro, Yoko Takahashi, Takayuki Kobayashi, Takahiro Kogawa, Tomohiko Ohta, Shigehisa Kitano, Takayuki Ueno, Shinji Ohno

“…TNBC is considered a subtype in which the cyclic GMP‐AMP synthase (cGAS) is linked to the stimulator of interferon genes (STING) pathway, an innate immune response that recognizes cytosolic nucleic acid components, is activated when DNA damage occurs, and is attracting attention as a new therapeutic target. …”
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Baseline cohort data from HARMONY, a cluster randomised controlled trial of culturally safe domestic violence management in general practice by Angela J. Taft, Felicity Young, Kelsey L. Hegarty, Jane Yelland, Danielle Mazza, Douglas Boyle, Richard Norman, Claudia García-Moreno, Cattram Nguyen, Xia Li, Bijaya Pokharel, Molly Allen Leap, Gene Feder

“…Abstract Background Domestic violence and abuse (DVA) is a globally prevalent, health damaging problem. In high income countries, migrant /refugee populations from low/middle income countries often consist of young families. …”
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KONDISI GEOLOGI LOKAL KOTA BENGKULU BERDASARKAN GROUND SHEAR STRAIN (GSS) by Nanang Sugianto, M. Farid, Suhendra Suhendra

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Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma by Akihiko Kawahara, Jun Akiba, Hirohisa Yano, Ambrogio Fassina, Rocco Cappellesso, Yoshiki Naito, Maria Guido, Paolo Simioni, Giuliana Cortese, Lorenzo Nicolè, Tiziana Sanavia, Valeria Maffeis, Claudia Maria Radu, Davide Serafin, Giacomo Zanus

“…As demonstrated in other solid neoplasms and HCC, infiltrating CD8+ T cells seem to be related to a better prognosis, but the mechanisms affecting the immune landscape in HCC are still mostly unknown. Necroptosis is a programmed, caspase-independent cell death that, unlike apoptosis, evokes immune response by releasing damage-associated molecular factors. …”
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Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma by Junjie Wang, Pixu Gong, Qingqing Liu, Menglei Wang, Dengfang Wu, Mengyu Li, Shujie Zheng, Han Wang, Han Wang, Qiaoming Long

“…Single-cell transcriptome profiling revealed that LAP treatment determines an immunosuppressive hepatic T-cell program that is characterized by a significantly reduced cytotoxic activity. …”
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Exploring RPA1-ETAA1 axis via high-throughput data analysis: implications for PD-L1 nuclear translocation and tumor-immune dynamics in liver cancer by Gaofeng Qin, Gaofeng Qin, Zengkuan Chen, Zengkuan Chen, Weihong Tian, Hongbo Chen, Yu Zhang, Yu Zhang, Wangzhi Wei, Wangzhi Wei

“…IntroductionETAA1 is recruited to DNA damage sites via its RPA -binding and ATR -activating domain (AAD) motifs, where RPA binding is crucial for ETAA1’s regulation of ATR activity. …”
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