Separable roles of the DNA damage response kinase Mec1ATR and its activator Rad24RAD17 during meiotic recombination. by Margaret R Crawford, Jon A Harper, Tim J Cooper, Marie-Claude Marsolier-Kergoat, Bertrand Llorente, Matthew J Neale

“…During meiosis, programmed DNA double-strand breaks (DSBs) are formed by the topoisomerase-like enzyme, Spo11, activating the DNA damage response (DDR) kinase Mec1ATR via the checkpoint clamp loader, Rad24RAD17. …”
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Protective Effects of a Probiotic <i>Lacticaseibacillus paracasei</i> MSMC39-1 on Kidney Damage in Aged Mice: Functional Foods Potential by Pol Sookpotarom, Jirapat Namkaew, Kaikwa Wuttisa, Chantanapa Chantarangkul, Praewpannarai Jamjuree, Thiranut Jaroonwitchawan, Malai Taweechotipatr

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Enhanced chemotherapy response in hepatocellular carcinoma: synergistic effects of miR-122 and doxorubicin co-delivery system inducing apoptosis and DNA damage by Xiuyun Lin, Jie Liu, Guangfeng Wu, Xiu Yang, Wenqiang Yan, Nanfeng Fan, Hui Li

“…This synergistic mechanism disrupts DNA repair, amplifying DNA damage and apoptosis. Our cytotoxicity and apoptosis assays (with a HepG2 cell apoptosis rate of 85.98%) demonstrated the potent antitumor capability of Fe-miR-122/DOX. …”
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Relationship between programmed cell death and targeted therapy for thyroid cancer in patients with a poor prognosis: an update by Yuejia Zhao, Simeng Zhao, Zhe Fan, Yongfu Zhao, Guangzhi Wang

“…Therefore, a comprehensive understanding of the underlying carcinogenesis mechanisms of thyroid cancer is required. Programmed cell death (PCD) is a cell death process mediated by specific molecular program, regulated by specific genes within the cell. …”
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Effectiveness of a school-based fire preparedness program on the knowledge and skills for fire response among primary school students by Anchalee Katramee, Weerapong Thanjangreed

“… Introduction: In the border region of Thailand, the absence of a standardized school preparedness program exposes schools to the risk of fires, which can result in injuries, fatalities, and property damage. …”
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Smoking and endometriosis: A narrative review by Alexandre Vallée, Anis Feki, Loic Josseran, Jean-Marc Ayoubi

“…Public health policies should incorporate targeted smoking prevention and cessation programs for women at risk.…”
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Porphyromonas Gingivalis Virulence Factors and their Role in Undermining Antimicrobial Defenses and Host Cell Death Programs in the Pathobiology of Chronic Periodontal Disease by Płonczyńska Alicja, Prucsi Zsombor, Sochalska Maja, Potempa Jan

“…Host cells, including oral keratinocytes, gingival fibroblasts, and monocytes/macrophages, regulate the immune response that drives chronic inflammation and tissue damage in PD. Programmed cell death pathways – apoptosis, pyroptosis, and necroptosis – are key regulators of the immune response. …”
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Preseason neuromuscular versus endurance training leads to greater improvements in isokinetic strength, muscle damage, and inflammation parameters in highly trained female soccer p... by Ali Belamjahad, Claire Tourny, Anthony C. Hackney, Nidhal Jebabli, Naoual Chariba, Fatiha Laziri, Ayoub Saeidi, Ismail Laher, Urs Granacher, Hassane Zouhal

“…The question arises whether the training programs induce muscle damage and inflammatory processes which may have a negative impact on players’ readiness at the beginning of the season. …”
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Knockdown of USF1 and USF2 drives prolonged changes in the gene expression response of M12-5B3 cells to DNA damage. by Kimberly S Bellingham-Johnstun, Lisa A Metzger, Jennifer L Stone, Kevin Gerrish, Pierre R Bushel, Michael L Sikes

“…Healthy cells exposed to genotoxic insult rapidly activate both p53-dependent and -independent non-genetic programs that pause the cell cycle and direct either DNA repair or apoptosis. …”
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Effect of temperature and relative humidity on oviposition, survival and seed damage by Callosobruchus maculatus on different hosts and evaluation of pigeon pea (Cajanus cajan) cul... by DHRUV SINGH, T BOOPATHI, D V SINGH, L GEETHANJALI

“…BSMR-198 recorded the highest seed damage, followed by WSA-1, BSMR-146, T-21, and Bahar. …”
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Srs2 binding to proliferating cell nuclear antigen (PCNA) and its sumoylation contribute to replication protein A (RPA) antagonism during the DNA damage response by Jiayi Fan, Nalini Dhingra, Tammy Yang, Vicki Yang, Xiaolan Zhao

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Citrus Pest Quick Guide: Flower Thrips by Jamie D Burrow, Lauren M Diepenbrock

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α-Terpineol Induces Shelterin Components TRF1 and TRF2 to Mitigate Senescence and Telomere Integrity Loss via A Telomerase-Independent Pathway by Marianna Kapetanou, Sophia Athanasopoulou, Andreas Goutas, Dimitra Makatsori, Varvara Trachana, Efstathios Gonos

“…Therefore, protecting telomeres from DNA damage is essential in order to avoid entry into senescence and organismal aging. …”
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In Vitro Sensitivity of Isolates of <i>Neopestalotiopsis rosae</i>, Causal Agent of Strawberry Crown Rot, to Usnic Acid by Laura Castro-Rosalez, Antonio Juárez-Maldonado, Adalberto Benavides-Mendoza, Susana González-Morales, Elizabeth García-León, Angel Rebollar-Alviter, Fabián Pérez-Labrada

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In-vivo antioxidant and therapeutic effects of ellagic acid on ischemia-reperfusion injury in skeletal muscle by Huseyin Demirtas, Abdullah Ozer, Dilara Yigit, Ali Dogan Dursun, Zeynep Yigman, Cagla Kosa, Aysegul Kucuk, Elif Simsek, Mustafa Arslan

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Pemahaman Hadis Konservasi Lingkungan dan Internalisasinya Pada Civitas Akademika Program Studi Ilmu Hadis IAIN Kediri by Umi Hanik, Ibnu Hajar Ansori, A Zahid

“…Otherwise, an environment that is treated badly will repay with damage and disaster. The leadership of the Faculty of Ushuluddin and Da'wah at IAIN Kediri was fully aware of this, especially the Hadith Science Study Program. …”
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Evaluasi Tebal Perkerasan Lentur Akibat Beban Berlebih Dengan Metode Austroads Menggunakan Program Circly 6.0 by Anita Rahmawati, Muhammad Iqbal, Emil Adly

“…Hal ini ditandai dengan nilai Cumulative Damage Factor (CDF) ≤1…”
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Lipopolysaccharide Induces Mitochondrial Fragmentation and Energetic Shift in Reactive Microglia: Evidence for a Cell-Autonomous Program of Metabolic Plasticity by Marcelle Pereira dos Santos, Vitor Emanuel Leocadio, Lívia de Sá Hayashide, Mariana Marques, Clara Fernandes Carvalho, Antonio Galina, Luan Pereira Diniz

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A Potent Fluorescent Derivative of 8-Hydroxyquinoline Suggests Cell Wall Damage as a Possible Cellular Action of the 5-Triazole 8-Hydroxyquinoline Class by Caroline de Bem Gentz, Marcela Silva Lopes, Priscilla Maciel Quatrin, Mariana Pies Gionbelli, Maycon Antonio de Cesare, Ana Paula Perin, William Lopes, Alexandre Meneghello Fuentefria, Marilene Henning Vainstein, Saulo Fernandes de Andrade

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Effects of L-carnitine supplementation on markers of exercise-induced muscle damage in healthy adults: A systematic review and meta-analysis of randomized controlled trials by Fatemeh Kazeminasab, Maryam Miraghajani, Saideh Ahmadinejad, Fatemeh Sharafifard, Randhall B. Carteri, Scott C. Forbes, Filipe J. Teixeira, Heitor O. Santos

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