Corporate Financing and Risk Management in the Banking Sector in Uganda During and Post Covid-19. Evidence from Kabale District by Byamukama, Eliab Mpora

“…The bank undertakes regular monitoring of the total value of gross daily payments made and received (M = 4.8, SD = 0.18). …”
Get full text

Size distribution of extracellular vesicles in pretreatment ascites and plasma is correlated with primary treatment outcome in advanced high-grade serous carcinoma by Maruša Herzog, Ivan Verdenik, Borut Kobal, Katarina Černe

“…Abstract To improve the treatment outcome and survival of patients with advanced high-grade serous carcinoma (HGSC), prognostic biomarkers for assessing the feasibility of complete (R0) or optimal (R1) primary cytoreductive surgery are needed. Additionally, biomarkers for predicting the response to neoadjuvant chemotherapy (NACT) in patients with primary inoperable disease could help stratify patients for tailored therapy and improve personalised approach. …”
Get full text

IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

“…Exogenous 4-octyl itaconate (OI) supplementation promoted the expression of Nrf2 and TIM4 and restored IRG1-/- bone marrow-derived macrophage (BMDM) efferocytosis, whereas inhibition of Nrf2 mediated by ML385 led to impaired efferocytosis of BMDMs, decreased expression of TIM4, and aggravated liver inflammation injury. Additionally, after supplementing Nrf2-/- BMDMs with exogenous OI, we evaluated the changes in its efferocytosis effect, efferocytosis did not change, and the protective effect of OI disappeared. …”
Get full text

Association between the low-density lipoprotein to high-density lipoprotein ratio and prognosis in critically ill intracerebral hemorrhage patients: a retrospective cohort study fr... by Yuchen Liu, Houxin Fu, Yue Wang, Yi Zhong, Rongting Zhang, Jingxuan Sun, Tianquan Yang, Yong Han, Yongjun Xiang, Bin Yuan, Ruxuan Zhou, Min Chen, Hangzhou Wang

“…Initially, the association between LHR and short-term outcomes in ICH patients, including ICU mortality, in-hospital mortality, and 28-day mortality, was analyzed using Cox regression in both continuous and categorical models. Additionally, restricted cubic spline (RCS), subgroup, and sensitivity analyses were conducted to further validate our findings. …”
Get full text

Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow by Liao X, Liu H, Li Y, Zhang W, Dai Q, Wei H, Zhou J, Xie X, Zhou H

“…This study aims to investigate the alterations in the HPA and its potential roles during IBD development.Methods: We utilized a dextran sodium sulfate (DSS)-induced colitis model in mice and employed immunofluorescence, real-time quantitative PCR (RT-qPCR), enzyme-linked immunosorbent assay (ELISA), among other techniques, to evaluate the impact of colitis on the HPA. Additionally, we used flow cytometry, adeno-associated virus-mediated gene silence, parabiosis and single-cell RNA sequencing to uncover the specific roles and mechanisms of the HPA in colitis.Results: Our results indicate that colitis activates HPA secretion and increases α-MSH. α-MSH acts on the MC5R present on the surface of hematopoietic stem cells (HSCs) in the bone marrow, altering the bone marrow microenvironment and promoting HSCs proliferation and differentiation into neutrophils. …”
Get full text

Perioperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement: an observational study by Gehad Awad, Fetoh Alaaeldin Fetoh, Noureldin Noaman Gwely, Usama Hamza, Sameh Amer, Yomna Mohammed Yehya, Amr Abdellateef

“…Abstract Background Minimally invasive mitral valve surgery has been introduced as a safe alternative to full sternotomy through smaller chest wall incisions to reduce the potential sternal complications in addition to the favorable aesthetic effect. This observational study has been designed to evaluate and compare operative and short-term postoperative outcomes of video-assisted versus right anterior thoracotomy mitral valve replacement. …”
Get full text

Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes by Chloe Wong, Jun Yan Ng, Yang Yie Sio, Fook Tim Chew

“…Future research that targets the same SNP across multiple populations could strengthen the association of additional loci with skin ageing. Further investigation into these underlying biological processes would significantly advance our understanding of the pathogenesis of skin ageing phenotypes.…”
Get full text

Evidence-informed language: interpretation and impact on intentions to treat – results of an online survey of medical students and specialists in German-speaking countries by Sven Benson, Reinhard Griebenow, Justine Schmidt, Henrik Herrmann

“…To this end, participants were asked to grade the relative weight of the expression for the results of a randomised trial versus two proposals for how to express the results of non-randomised studies. (2) Next, strong positive, weak positive, weak negative and strong negative clinical recommendations were presented, and participants were asked to answer in a forced-choice format if they would treat all/no patients, selected patients or only consider treatment. Additionally, the number of eligible patients who would be treated was assessed.Results N=1081 physicians and N=539 medical students completed the survey. (1) Less than half of the participants (48.5%) interpreted use of ‘associated with’ as linguistic differentiation between results from randomised versus non-randomised trials in a sense as put forward by the proponents. …”
Get full text

Comprehensive analysis of peripheral dose in electron beam therapy with a Varian TrueBeam Linac by Kapil Dev Maharaj, Mahsheed Sabet, Joshua Dass, Mounir Ibrahim, Talat Mahmood, Pejman Rowshanfarzad

“…Peripheral doses remained below 5% of the maximum dose approximately 10–15 ​mm away from the field edges, suggesting the potential for implementing additional shielding where required. Conclusions: This study highlights the importance of considering peripheral doses in electron radiotherapy. …”
Get full text

Carbapenem-resistant Enterobacterales (CRE) colonisation as a predictor for subsequent CRE infection: A retrospective surveillance study by Courtney M. Tubb, Marco Tubb, Jonathan Hooijer, Rispah Chomba, Jeremy Nel

“…Method: We retrospectively reviewed hospital records from 686 patients admitted to a medical high-care ward at a tertiary hospital in Gauteng, South Africa, between October 2019 and May 2022. …”
Get full text

The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…A retrospective medical record review was conducted of all adult patients (≥18 years old) admitted between August 2013 and August 2018 to a tertiary referral centre in Cape Town, SA, with paracetamol poisoning and biochemical evidence of liver impairment. …”
Get full text

Designing a Stock Recommender System Using the Collaborative Filtering Algorithm for the Tehran Stock Exchange by Marziyeh Nourahmadi, Ali Rahimi, Hojjatollah Sadeqi

“…The overall index returned 16 times during this period, indicating the excellent performance of the strategy over time. Additionally, the value at risk (VaR) for the selected method during the study period stood at -12.8%, indicating the lower risk of this method. …”
Get full text

De la neuroplasticidad a las propuestas aplicadas: estimulación temprana y su implementación en Costa Rica / From Neuroplasticity to Applied Proposals: Early Stimulation and Its Im... by Johanna Sibaja-Molina, Tracy Sánchez-Pacheco, Mijail Rojas-Carvajal, Jaime Fornaguera-Trías

“…In this context, a brief approximation to the ES background is provided, as well as a general framework about brain plasticity. In addition, the theoretical and practical perspective of the ES practitioners is also described by detailing the empirical evidence around its most known/used variants in Costa Rica (i.e., Doman-Delacato, Snoezelen®, Point and Bebé políglota). …”
Get full text

Analyzing the Effect of Dividends on Default Probability According to Signaling and Agency Theories by Alireza Najjarpour, Saeed Fathi, Ali Foroush Bastani

“…ObjectiveThe probability of default is one factor that determines the cost of capital due to its role in credit risk. Dividend as a sign of cash flow or as a sign of ownership of wealth is one of the factors affecting the probability of default. …”
Get full text

Identifying Organizational Factors and Components Influencing Customer Experience Management Maturity: A Meta-synthesis Approach by Payam Mardazad Navi, Kambiz Heidarzadeh Hanzaee, Seyyed Buik Mohammadi, Mohsen Khoon Siavash

“…As a potent approach, it requires dedicated governance and processes to ensure success and institutionalize it throughout the organization. Additionally, paying attention to alignment frameworks between current business processes, visions, and strategies with customer experience is crucial.…”
Get full text

Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging by Zhiqiang Qiu, Tianci Liu, Chengxi Zeng, Maojiang Yang, HongYing Yang, Xiaoxue Xu

“…ObjectiveTo explore the changes in the white matter microstructure of the ascending pain conduction pathways in patients with chronic neck and shoulder pain (CNSP) using combined brain and spinal cord diffusion tensor imaging techniques, and to assess its correlation with clinical indicators and cognitive functions.Materials and methodsA 3.0T MRI scanner was used to perform combined brain and spinal cord diffusion tensor imaging scans on 31 CNSP patients and 24 healthy controls (HCs), extracting the spinothalamic tract (STT) and quantitatively analyzing the fractional anisotropy (FA) and mean diffusivity (MD) which reflect the microstructural integrity of nerve fibers. Additionally, these differences were subjected to partial correlation analysis in relation to Visual Analog Scale (VAS) scores, duration of pain, Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS).ResultsCompared to HCs, CNSP patients showed decreased mean FA values and increased mean MD values in bilateral intracranial STT compared to the HC group, but two-sample t-test results indicated no statistically significant differences (p > 0.05). …”
Get full text

Lethal necrotizing granulomatous vasculitis after bariatric surgery and bilateral mammaplasty by O. V. Blagova, D. Kh. Aynetdinova, A. V. Nedostup, N. A. Novikova, Ye. A. Kogan, Yu. V. Lerner, L. V. Kozlovskaya, V. V. Rameyev, N. A. Mukhin

“…The relation of atypical necrotizing vasculitis with yet undescribed clinical presentation with previous bariatric surgery and long-standing malabsorption is highly probable; application of silicone implants with adjuvant-associated immune response were additional resolving factors. Incomplete effect of immunosuppressive therapy indicates the dominant role of autoinflammation in the course of disease. …”
Get full text

Inpatient preferences among patients with multiple chronic conditions in China: A discrete choice experiment by Yueqin Wang, Shiyin Wu, Yuehua Chen, Ling Xiao, Qingling Su, Xiaoyin Huang, Weikang Wang, Wanxin Li, Shanshan Du, Wenbin Liu, Weimin Ye

“…Results A total of 504 valid questionnaires were included in the analysis. …”
Get full text

Examining the Impact of Cognitive and Emotional Factors on Consumer Behavioral Responses in Online Behavioral Advertising by Hossein Norouzi, Bahareh Osanlou, Ali Saleh Gohari

“…Findings The findings reveal that perceived personalization positively influences perceived relevance, diminishes perceived intrusiveness, and enhances behavioral responses to advertisements. Additionally, information control demonstrates a negative impact on perceived intrusiveness and privacy concerns, while persuasion knowledge exhibits a positive correlation with privacy concerns. …”
Get full text

The Role of Mature Brain-Derived Neurotrophic Factor and Its Precursor in Predicting Early-Onset Insomnia in Stroke Patients Experiencing Early Neurological Deterioration by Shi G, Yu P, Wang Z, Xu M, Guo M, Wang X, Zhou R

“…The areas under the curve (AUC) for mBDNF and the mBDNF/proBDNF ratio were 0.686 and 0.778, respectively.Conclusion: Our study identified a correlation between reduced mBDNF levels and a decreased mBDNF/proBDNF ratio with the development of EOI in END patients. In addition, the mBDNF/proBDNF ratio may provide greater insight as a promising biomarker for EOI than mBDNF or proBDNF alone.Keywords: brain-derived neurotrophic factor, ischemic stroke, insomnia, early neurological deterioration, biomarker…”
Get full text