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6321
The efficacy of mindfulness-based interventions for patients with COPD: a systematic review and meta-analysis protocol
Published 2019-05-01“…Randomised controlled trials(RCTs)/quantitative studies, qualitative studies and case studies on the effect of MBIs in patients with COPD aged over 18 years will be included. …”
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6322
NT5E (CD73) as a prognostic biomarker and therapeutic target associated with immune infiltration in lung adenocarcinoma
Published 2025-02-01“…A strong positive correlation was observed between NT5E expression and the presence of immune cells, including dendritic cells, macrophages, and CD4+ T cells, as well as the expression of various immune cell markers, suggesting that NT5E may influence the prognosis of LUAD patients by regulating immune cell infiltration. Additionally, drug sensitivity analysis highlights the potential of selumetinib and PD318088, both MEK1/2 inhibitors, to target NT5E in LUAD treatment, suggesting their use as single agents or in combination with other therapies. …”
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6323
Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study
Published 2025-02-01“…Lymphoscintigraphy detected SLN in 407 of 428 (95.09 %) patients in group 2. Due to the additional SLN imaging in group 2, the time between radiotracer injection and start of surgery was significantly prolonged (p < 0.001). …”
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6324
Vagal nerve stimulation dynamically alters anxiety-like behavior in rats
Published 2025-03-01“…Anxiety-like behavior was assessed using the elevated plus maze, open field test, and novelty-suppressed feeding test. Additionally, a place preference assay determined whether VNS is rewarding or aversive. …”
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6325
Seed priming and abiotic stress tolerance in carrot: Unraveling the mechanisms of improved germination.
Published 2025-01-01“…These findings underscored the importance of genotype-specific adaptations in conferring salinity or drought tolerance in carrot seedlings. …”
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6326
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis
Published 2025-02-01“…ATAC-seq analysis revealed that glycolysis in BC cells enhanced chromatin accessibility. Additionally, we confirmed that HDAC2 and HDAC3 act as “erasers” for H3 lysine lactylation. …”
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6327
Cost-effectiveness Analysis of Lorlatinib in Patients Previously Treated with Anaplastic Lymphoma Kinase Inhibitors for Non-small Cell Lung Cancer in Greece
Published 2022-02-01“…Primary outcomes were patient life years (LYs), quality-adjusted life years (QALYs), total costs, and incremental cost-effectiveness ratios per QALY and LY gained. …”
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6328
Pyrolysis and Dioxin Production Characteristics of Mineralized Waste in Landfills
Published 2023-11-01“…During the pyrolysis, the PCDD/F concentration of MW is higher than that of the original MSW. After the addition of 30% biomass, the PCDD/F content increases to 16.92 ng m−3. …”
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6329
Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020.
Published 2025-01-01“…Its episodic occurrence makes it difficult to identify and measure its prevalence and trends in the population. Additionally, there is limited data on disparities and trends in mortality due to paroxysmal tachycardia, which is essential for assessing current medical approaches and identifying at-risk populations.…”
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6330
Outcomes for Dostarlimab and Real-World Treatments in Post-platinum Patients With Advanced/Recurrent Endometrial Cancer: The GARNET Trial Versus a US Electronic Health Record-Based...
Published 2023-09-01“…**Discussion:** Consistent with previous analyses, patients treated with dostarlimab had significantly longer OS than patients in the US real-world cohort after adjusting for the lack of randomization using stabilized IPTW. Additionally, patients had a long TTD when treated with dostarlimab, suggesting a favorable tolerability profile. …”
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6331
Biochemical analysis of miR-217 and miR-532 in patients with fibromyalgia
Published 2025-02-01“…This study included 80 participants who splitted into two groups: 40 fibromyalgia sufferers (12 male and 28 female), and 40 healthy volunteers (10 male and 30 female) who served as the control group. …”
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6332
Higher AVCO2 and Lactate Gradient Combined with SOFA Score as a Mortality Predictor during the 6-Hours of Resuscitation of Septic Shock
Published 2024-10-01“…In this prospective observational-analytical study patients with septic shock admitted to the ICU were evaluated. Sepsis is defined as patients who had 1 or more of the SIRS criteria with a possible or proven source of infection and hypotension despite appropriate fluid therapy who needed to receive vasopressors. …”
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6333
An Insurance Value Modeling Approach That Captures the Wider Value of a Novel Antimicrobial to Health Systems, Patients, and the Population
Published 2023-07-01“…They can be supplemented by additional value elements including insurance value, which captures the value of an antimicrobial in preventing or mitigating impacts of adverse risk events. …”
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6334
Assessment of Knowledge Gaps in Cervical Cancer Screening and HPV Vaccination Among Chinese Women: A Comprehensive Population-Based Study
Published 2025-02-01“…Participants completed a questionnaire assessing CCS awareness and participation. Additionally, HPV vaccine knowledge was investigated in a sub-sample of 17,010 women aged < 45 years.Results: The mean age of participants was 45.06 years (SD: 8.52). …”
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6335
Comparison of ultraviolet C light and isopropyl alcohol for the disinfection of cellular phones in a paediatric intensive care unit setting
Published 2024-11-01“…The reduction ratio of colony-forming units (CFUs) before and after intervention was analysed using the Mann-Whitney U-test. In addition, the effectiveness of the disinfection methods was compared using the Wilcoxon signed-rank paired test. …”
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6336
Social isolation in the young and middle-aged patients with stroke: role of social support, family resilience and hope
Published 2025-02-01“…In the mediating effects model, social support could influence social isolation directly (95% CI -0.250, -0.061) or indirectly through family resilience (95% CI -0.136, -0.062) or patient hope level (95% CI -0.078, -0.017). In addition, Family resilience and hope had a significant chain mediating effect between social support and social isolation (95% CI -0.029, -0.006).ConclusionsSocial support can have both direct and indirect effects on social isolation through the mediating factors of family resilience and hope. …”
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6337
Patient Perspective on Robotic-Assisted Total Joint Arthroplasty
Published 2025-02-01“…Most patients did not consider robotic TJA as minimally invasive surgery, with 61.7% stating they are not the same. In addition, 52.3% were not comfortable with extra or longer incisions for robotic procedures. …”
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6338
Prevalence of nutritional anemia and its risk factors in children under five in the Gaza Strip
Published 2025-02-01“…Family characteristics like the father’s age, smoking habits, the mother’s education, employment, marital history, income, housing ownership, and a history of anemia during pregnancy also played a role. …”
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6339
The decision-making process and experiences of women returning to work after parental leave: a qualitative systematic review protocol
Published 2025-02-01“…Abstract Objective To investigate the decision-making process of women returning to work after maternity leave or parental leave and explore the influence of cultural norms and societal expectations on their choices. Additionally, we seek to understand the lived experiences of the women in this context. …”
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6340
Understanding sociodemographic differences in climate behavior, climate policy acceptance, and political participation
Published 2025-01-01“…In contrast, levels of political participation were higher for men and younger individuals. …”
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