Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

“…Furthermore, it discusses the role of Clec9a in the induction and functional activation of Clec9a+ cDC1s, with a particular focus on addressing the challenges related to off-target effects and immune tolerance in the development of tumor vaccines. Additionally, this review explores the potential of Clec9a-targeted approaches to enhance the immunogenicity of tumor vaccines and addresses the utilization of Clec9a as a delivery target for specific agonists (such as STING agonists and αGC) to enhance their therapeutic effects. …”
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Comparative analysis of consistency of adaptations to interval interventions individualized using sport-specific techniques in well-trained soccer players by Hongjun Zhang, Sheng Li, Bingyuan Yang

“…Analyzing inter-individual variability through determining residuals in individual changes indicated HIITvIFT results in residuals in individual changes in ventilatory threshold (VT [first (VT1) and second (VT2)]), and peak and average power output than SSG (p = 0.02, 0.04, 0.02, and 0.01, respectively). In addition, the change in maximum oxygen uptake, maximal ventilation, and average power output following HIITvIFT was notably greater than SSG (p = 0.002, 0.006, and, 0.019, respectively). …”
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Point-of-care lung ultrasound in detecting pneumonia: A systematic review by Iqra Abid, Nadia Qureshi, Nicola Lategan, Simon Williams, Sidra Shahid

“…Statistical analysis using Stata Version 16 determined pooled sensitivity and specificity via a bivariate model, emphasizing LUS and CXR diagnostic capabilities. Additionally, RevMan 5.4.1 facilitated the calculation of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), offering insights into diagnostic accuracy…”
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Prophylactic antibiotics in laparoscopic cholecystectomy: Reducing postoperative infection risk–A meta-analysis and trial sequential analysis by Shufeng Wang, Qing Gao, Xiaogang Qi, Lihua Hong, Hai Huang

“…Data extraction and meta-analysis were performed. Additionally, trial sequential analysis was conducted to assess the robustness of evidence in meta-analysis. …”
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Vegetative Propagation of Perennial Cut Flower Flax (Linum spp.) in a Controlled Environment by Elizabeth A. Goodman, Neil O. Anderson

“…Perennial flax vegetative propagation may be successful using 1000 ppm IBA for 4 weeks to multiply GH stock plants and produce plugs (liners) for shipping and CF production. Additional research will be needed to define the timing and cultural requirements for successful shipping of vernalized, finished (rooted, robust growth) plugs for perennial CF flax cultivars.…”
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Cost-Utility Analysis of Add-on Cannabidiol vs Usual Care Alone for the Treatment of Seizures in Patients With Treatment-Resistant Lennox-Gastaut Syndrome or Dravet Syndrome in the... by Jamshaed Siddiqui, Sally Bowditch

“…**Results:** In patients with LGS, CBD plus usual care led to additional costs of €28 338 and increased quality-adjusted life-years (QALYs) of 1.318 compared with usual care alone. …”
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Exploring advanced nanostructures and functional materials for efficient hydrogen storage: a theoretical investigation on mechanisms, adsorption process, and future directions by Gourhari Jana, Pratim Kumar Chattaraj

“…Functionalization of γ-GNT with OLi2 at boron-doped sites significantly enhances storage potential, achieving optimal hydrogen binding energies for practical applications. Additionally, metal acetylide and cyanide complexes, stabilized by noble gas insertion, display thermodynamically favorable hydrogen adsorption. …”
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Regional cerebral oxygen saturation during initial mobilization of critically ill patients is associated with clinical outcomes: a prospective observational study by Ryota Imai, Takafumi Abe, Kentaro Iwata, Seigo Yamaguchi, Takeshi Kitai, Atsuhiro Tsubaki

“…Methods This prospective study included critically ill patients admitted to the Uonuma Kikan Hospital Emergency Center who received physical therapy between June 2020 and December 2022. …”
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Long-term efficacy and safety of endoscopic surgery versus small bone window craniotomy for spontaneous supratentorial intracerebral hemorrhage: a meta-analysis and trial sequentia... by Chen Guo, Yang Bai, Xiaobin Zhang, Pinjing Zhang, Song Han, Di Fan

“…Following the meta-analysis, a trial sequential analysis (TSA) was conducted to validate the findings. Results Six randomized controlled trials were included in the meta-analysis. …”
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A Bidirectional Mendelian Randomization Study Investigating the Causal Relationship Between Ankylosing Spondylitis and Chronic Obstructive Pulmonary Disease by Pan D, Dai X, Li P, Xue L

“…The primary MR method employed was Inverse-Variance Weighting (IVW), supplemented by additional MR methods such as weighted median, MR-Egger, simple mode, and weighted mode. …”
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Charge-on-the-move solutions for future mobility: A review of current and future prospects by Mohd Aiman Khan, Wilco Burghout, Oded Cats, Erik Jenelius, Matej Cebecauer

“…Simultaneously, emerging transportation modes such as autonomous vehicles, shared mobility, modular systems, and aerial vehicles, introduce additional complexities, demanding more innovative charging solutions. …”
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Comparison of 8 Weeks of Selected TRX Training and Weight Training on Improving Motor Function and Chronic Nonspecific Back Pain in Women Aged 35 to 55 by Fatemeh Rezaei

“…These exercises appear to lower the risk of injury and enhance performance by improving motor function. Additionally, by applying theories that emphasize strengthening the core muscles and mobilizing the limbs, it can be concluded that participation in these exercises improves the performance of women suffering from musculoskeletal pain.…”
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Atmospheric Wet Deposition of PCDD/Fs in the Ambient Air by Xueying Tian, Kangping Cui, Hwey-Lin Sheu, Yen-Kung Hsieh, Fanxuan Yu

“…When the total PCDD/Fs-WHO2005-TEQ concentrations in the air are washed away by a heavy rainfall, the PCDD/F concentrations are diluted.…”
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Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production by Parnian Arafi, Sujan Devkota, Emily Williams, Masato Maesako, Michael S Wolfe

“…Here, we conducted full quantitative analysis of all proteolytic events on APP substrate by γ-secretase with six additional PSEN1 FAD mutations and found that all six are deficient in multiple processing steps. …”
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Pulmonary Mucormycosis – An Experience from a Tertiary Care Center in Southern India: A PULM MUCOR Study by Ashwin Oliver Arul, K. Rajiv Karthik, Devasahayam Jesudas Christopher

“…The most common computed tomography (CT) scan findings were consolidations and cavitations. Majority of the samples 25/37 (67%) were acquired using bronchoscopy. …”
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Effect of age on the treatment duration and proposed “impacted incisor severity score” of impacted maxillary incisor: A retrospective study by Umer Mukhtar, Manoj kumar Jaiswal, Rigzen Tamchos, Ashima Goyal, Satinder Pal Singh, Aditi Kapur

“…After initial screening of the digital records, 75 cases with 80 impacted maxillary central incisors were recruited; 9 cases were excluded due to incomplete records. …”
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Phytomedicine nanoformulations for Parkinson's disease by Chinthu V. Saji, K P Mohanakumar, Rajesh A Shenoi

“…In vitro studies demonstrated enhanced cellular uptake and neuroprotective effects, while in vivo models showed improved pharmacokinetics, BBB permeability and neuroprotective outcomes. Additionally, nine plant-derived compounds with potential effects against PD, but are not nanoformulated were investigated, highlighting their neuroprotective mechanisms but exposing the existing limitations. …”
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Involving migrants in the development of guidelines for communication in cross-cultural general practice consultations: a participatory learning and action research project by Chris van Weel, Anne MacFarlane, Maria van den Muijsenbergh, Tomas de Brún, Evelyn van Weel-Baumgarten, Mary O'Reilly-de Brún, Ekaterina Okonkwo, Jean Samuel Bonsenge Bokanga, Maria Manuela De Almeida Silva, Florence Ogbebor, Aga Mierzejewska, Lovina Nnadi

“…In this paper, we focus on findings about the use of formal versus informal interpreters because dialogues about these issues emerged as central to the identification of recommendations for best practice.Design This qualitative case study involved a Participatory Learning and Action (PLA) research methodology.Participants The sample comprised 80 stakeholders: 51 from migrant communities; 15 general practitioners (GPs) and general practice staff; 7 established migrants as peer researchers; 5 formal, trained interpreters; and 2 service planners from the national health authority.Setting Galway, Ireland.Results There was 100% consensus across stakeholder groups that while informal interpreters have uses for migrants and general practice staff, they are not considered acceptable as best practice. …”
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EXPERIENCE OF IMPLEMENTING THE DISTANCE E-COURSE “STATISTICAL METHODS IN PHARMACY” IN THE MATHEMATICAL TRAINING OF FUTURE PHARMACEUTICAL SPECIALISTS by Iryna Zhovtonizhko, Maryna Nessonova, Mariana Barannyk, Nadiia Sheykina, Olga Marchenko

“…It is concluded, that the implementation of distance learning technology in the practice of Ukrainian higher pharmaceutical and medical education is necessary not only due to the current conditions that make it impossible to organize full-fledged offline education but also because of the efficiency of these technologies, primarily for organizing independent students’ work, that ensures the development of learners’ autonomy, contributes to the development of information culture, general digital competence, and a range of soft skills, including communication, interaction, collaboration in a digital environment, and the rational use of study time. …”
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Participatory research towards the control of snakebite envenoming and other illnesses in a riverine community of the Western Brazilian Amazon. by Alícia Patrine Cacau Santos, Evellyn Antonieta Rondon Tomé Silva, Hiran Sátiro Souza da Gama, Jady Shayenne Mota Cordeiro, Ana Paula Silva Oliveira, Jéssica Albuquerque Araújo, Rafaela Nunes Dávila, Hélio Afonso Amazonas Júnior, Altair Seabra Farias, Jacqueline Almeida Gonçalves Sachett, Vinícius Azevedo Machado, Wuelton Marcelo Monteiro, Felipe Leão Gomes Murta

“…Of these 42 individuals, 32 participated in the qualitative interviews, and 20 took part in the community assembly. …”
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