Assessment of in vitro skin permeation and accumulation of phenolic acids from honey and honey-based pharmaceutical formulations by Anna Nowak, Anna Muzykiewicz-Szymańska, Magdalena Perużyńska, Edyta Kucharska, Łukasz Kucharski, Karolina Jakubczyk, Paulina Niedźwiedzka-Rystwej, Justyna Stefanowicz-Hajduk, Marek Droździk, Juraj Majtan

“…Conclusions The obtained results confirmed the effectiveness of two pharmaceutical formulations in the form of a hydrogel or emulsion containing honey after applied topically. The inclusion of honey in the vehicle, in particular hydrogel increased the penetration of phenolic acids through the skin.…”
Get full text

Genomic analysis of the SMN1 gene region in patients with clinically diagnosed spinal muscular atrophy: a retrospective observational study by Tamaki Kato, Mamoru Yokomura, Yutaka Osawa, Kensuke Matsuo, Yuji Kubo, Taihei Homma, Kayoko Saito

“…We confirmed 3 hybrid SMN gene types in 5 patients that contained SMN2 gene sequence (aaTgg) flanked by upstream “t” and downstream “G” SMN1 sequence. …”
Get full text

Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…As regards the mechanism, ATP11B interacted with PD-L1 in a CKLF-like MARVEL transmembrane domain containing 6 (CMTM6)-dependent manner. The depletion of ATP11B promoted CMTM6-mediated lysosomal degradation of PD-L1, thus reactivating the immune microenvironment and inducing an antitumor immune response. …”
Get full text

Implementasi Algoritma Fuzzi Mamdani pada Sistem Pakar Menggunakan Software Aplikasi Matlab R2007B, Studi Kasus: Tanaman Hidroponik Selada Air by Okta Purnawirawan, Tri Afirianto

“…The expert system was built using the functions of the Fuzzy Inference System (FIS) contained in the Fuzzy Logic Toolbox (FLT) in the MATLAB R2007b application software. …”
Get full text

Implementasi Color Quantization pada Kompresi Citra Digital dengan Menggunakan Model Clustering Berdasarkan Nilai Max Variance pada Ruang Warna RGB by Tommy Tommy, Rosyidah Siregar, Andi Marwan Elhanafi, Imran Lubis

“…Abstract Image compression can be done by using color quantization where by reducing the number of colors contained in the image it can reduce the number of bits used to represent the colors. …”
Get full text

Effect of 25-hydroxycholecalciferol and high phytase doses on performance, vitamin D status, bone mineralization, and mechanistic target of rapamycin gene expression of broilers by L.S. Bassi, C.C.S. Martins, C.A. Lozano-Poveda, I.C. Dias, S.G. Oliveira, A. Maiorka

“…Two feeding phases were stablished (1-to-21 and 22-to-42 d) and all diets contained commercial levels of vitamin D3 (100 µg/kg) with total Ca and available P respectively set to 0.6 and 0.3%. …”
Get full text

Aplikasi Sistem Informasi Manajemen Pengiriman Barang PT. GST by Indra Budi Trisno, Darmanto Darmanto, Dimas Febrian Elvianto

“…The research methodology contained 5 stages such as preliminary study, formulation of goals and problems of the research, system analyst and design, system implementation and testing, deploying the system. …”
Get full text

Exploring the epidemiological impact of attractive targeted sugar bait against malaria in combination with standard malaria control by Nima R. Moghaddas, Mohamed M. Traore, Gunter C. Müller, Joseph Wagman, Javan Chanda, Julian Entwistle, Christen M. Fornadel, Thomas S. Churcher

“…It has been suggested that the percentage of wild mosquitoes caught fed on dye-containing sugar baits without the toxin could provide an entomological correlate of the potential epidemiological benefit of ATSB. …”
Get full text

SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate by Ernesto Luna, Sophie Ruiz, Marie Garinot, Cyril Chavagnac, Pankaj Agrawal, John Escobar, Laurent Revet, Marie-Jeanne Asensio, Fabienne Piras, Francis G. Fang, Donald R. Drake, Bachra Rokbi, Daniel Larocque, Jean Haensler

“…Abstract In the aim of designing and developing a novel saponin-based adjuvant system, we combined the QS21 saponin with low microgram amounts of the fully synthetic TLR4 agonist, E6020, in cholesterol-containing liposomes. The resulting adjuvant system, termed SPA14, appeared as a long-term stable and homogeneous suspension of mostly unilamellar and a few multilamellar vesicles, with an average hydrodynamic diameter of 93 nm, when formulated in citrate buffer at pH 6.0-6.5. …”
Get full text

Production of Biogas from Bio-Degradable Municipal Solid Waste – A Way of Resource Recovery. by Atatiru, Faiza

“…A Vario Macro cube elemental analyser was used for the quantification of Carbon, C (52.83 Wt %), Hydrogen, H (5.73 Wt %), Oxygen, O (33.23 Wt %), Nitrogen, N (1.68 Wt %) and Sulphur, S (0.87 Wt %) while Calorific Value (2388 Kcal/kg) was done by the bob calorimeter method. A plastic container (0.12m3) capacity was redesigned to be used as a bio digester. …”
Get full text

Factors Associated with Healthcare-Seeking Behavior among Health Profession Students in Selected Universities in Southwestern Uganda. by Wamaani, Hannington Gamukama, Olum, Ronald, Ajuna, Noble, Atwijukire, Humphrey, Kabami, Jane, Asiimwe, John Baptist

“…Data was collected using a Google form containing structured questions. The link to the questionnaire was sent to prospective participants via WhatsApp platform or email between September and November 2021. …”
Get full text

YOUTH RESTIVENESS IN NIGERIA: AN EVALUATION OF IKORODU LOCAL GOVERNMENT, LAGOS, NIGERIA by NIYI ADEGOKE, Odedokun Ezekiel Adeyemi, Odunayo Tolulope Ojo

“…The increasing rate of youth restiveness is alarming and it is posing serious challenges to developing countries of the world especially Nigeria with large population of youths. …”
Get full text

Impact of the COVID-19 pandemic on construction project performance: challenges and strategic responses by Eda Selcuk

“…This study examines the economic and financial challenges, material delivery and supply chain disruptions, workforce health issues, and contractual problems faced by construction companies during the COVID-19 pandemic across different countries. The research aims to determine the effects of these challenges on project and company performance using data obtained from survey conducted with 126 construction professionals including architects and construction engineers operating in seven different geographic locations. …”
Get full text

Promoting Lampung’s coffee to the Small Medium Enterprises (SMEs) in Turkey by Rindu Rika Gamayuni, N. Nairobi, Ernie Hendrawaty, Agrianti Komalasari, Arif Darmawan

“…The activity was carried out through three main stages: (1) Preparation: situation analysis, preparation of material, making brochures for Lampung coffee producers; (2) Implementation: providing material to participants discussion to strengthen understanding and application of the material. (3) Evaluation and Reporting: comprehensive evaluation of community service results so that the participants can get to know the characteristics and taste of coffee in two countries (Indonesia, especially Lampung coffee and Turkish coffee), can understand and learn strategies for increasing the quality and quantity of coffee products and their marketing. …”
Get full text

ENVIRONMENTAL IMPACT OF WATER TREATMENT PROCESS. A SYSTEMATIC REVIEW OF EVALUATION METHOD by FLORINA FABIAN, VALENTIN NEDEFF, MIRELA PANAINTE -LEHADUS, OANA IRIMIA, SILVIA RACOVITA

“…The ExternE method on the contrary aims to quantify external impacts, from both economic and social points of view, to weight each endpoint of the impact categories. …”
Get full text

HISTORICISING PARTY INTERNAL DEMOCRACY AND THE CHALLENGE OF DEMOCRATIC CONSOLIDATION IN NIGERIA’S FOURTH REPUBLIC, 1999-2023 by ADESOTE SAMSON ADESOLA, AKANDE SUNDAY ADEKUNLE

“…It concludes by suggesting ways of addressing the political menace in order to build up the country’s democracy from being nascent. The methodological approach adopted in this paper is historical, thematic and qualitative. …”
Get full text

Artificial intelligence (AI) or augmented intelligence? How big data and AI are transforming healthcare: Challenges and opportunities by K Moodley

“…Global guidelines are emerging to ensure governance in AI, but many low- and middle-income countries have yet to develop context- specific frameworks. …”
Get full text

Mexican Bromeliad Weevil (no official common name), Metamasius callizona (Chevrolat) (Insecta: Coleoptera: Curculionidae: Dryophthorinae) by Barbra Larson, J. Howard Frank

“….), was first reported in Florida in Miami-Dade County in 1984 and has since become an important pest of sugarcane, bananas, and ornamental palms. …”
Get full text

Culturally programmed space of nursery – where we are going? by Marta Śliwa, Marzenna Nowicka

“…The basic conclusion that emerges from the analysis of the accumulated body of research indicates that the spatial arrangement of kindergartens in post-communist countries still induces/ predisposes to the development of mirror identity operating efficiently under authoritarian rule. …”
Get full text

Starting a just transition in the context of macro-economic policy by Pavićević Nina, Ćosić Milivoje, Đorđević Vladimir

“…Also, there is increasing evidence that climate shocks and environmental risks have important implications for the financial stability of countries. Accordingly, all these developments impose the need for profound socioeconomic changes worldwide, aimed at promoting a "green economy". …”
Get full text