Early identification of mild cognitive impairment: an innovative model using ocular biomarkers by Lingjing Zhang, Lingjing Zhang, Yanwei Wang, Yuming Liu, Zi Ye, Zhaohui Li

“…Age-related cataract (ARC), a common ocular condition in elderly populations, correlates with a 1.43-fold increased risk of developing AD. …”
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Identification of serum biomarkers for cystic echinococcosis in sheep through untargeted metabolomic analysis using LC–MS/MS technology by Xiao-Xia Wu, Wan-Li Ban, Li-Jiang Wu, Wen-Jing Qi, Mehdi Borhani, Xiao-Ying He, Xiao-Lei Liu, Ming-Yuan Liu, Jing Ding

“…Orthogonal projections to latent structures–discriminant analysis (OPLS-DA) were used to analyze different metabolites in the serum of the two groups. …”
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EfficientNetB0-Based End-to-End Diagnostic System for Diabetic Retinopathy Grading and Macular Edema Detection by Long X, Gan F, Fan H, Qin W, Li X, Ma R, Wang L, Hu R, Xie Y, Chen L, Cao J, Shao Y, Liu K, You Z

“…Model performance was evaluated using multiple classification metrics, including accuracy, AUC, precision, recall, F1-score, and Cohen’s kappa coefficient.Results: In the first stage, the model achieved an accuracy of 0.7036 and an AUC of 0.9062 on the test set, demonstrating high accuracy and discriminative ability. …”
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Profiling type I and II interferon responses reveals distinct subgroups of pediatric patients with autoinflammatory disorders by Anaïs Nombel, PharmD, Magali Perret, MSc, Sophie Trouillet-Assant, PhD, Marine Villard, PhD, Christine Lombard, PharmD, Lorna Garnier, PharmD, Anne-Perrine Foray, MD, PhD, Sarah Benezech, MD, Remi Pescarmona, PharmD, Samira Khaldi-Plassart, PhD, Thierry Walzer, PhD, Alexandre Belot, MD, PhD, Sébastien Viel, PharmD, PhD

“…We also designed a NanoString assay to monitor type II ISGs and tested its value to discriminate clinical conditions. Methods: A total of 196 samples from patients with diseases associated or not with IFN-I pathway activation were analyzed by NanoString and Simoa. …”
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Metabolomic Profiling of the Blood of Patients with Chronic Consciousness Disorders by A. A. Orlova, E. A. Kondrat'eva, Ya. A. Dubrovskii, N. V. Dryagina, E. V. Verbitskaya, S. A. Kondratev, A. A. Kostareva, A. N. Kondratev

“…The underlying conditions of brain injury were TBI (2 in group 1 and 5 in group 2) and hypoxia (8 in group 1 and 1 in group 2). …”
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Overall Layout Method of Frame Structure Plane Based on Generative Adversarial Network by ZHONG Yan, LEI Xin, LONG Danbing, FANG Changjian, KANG Yongjun

“…Through adversarial training, the generator and discriminator iteratively improve until reaching a Nash equilibrium. …”
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A Study on the Genotype × Environment Interaction in Promising Advanced Genotypes of Soybean using Graphical GGE-biplot Analysis by Bahram Masoudi, Amir Gholizadeh, Parastoo Majidian, Ebrahim Hezarjaribi, Nasrin Razmi, Farnaz Shariati

“…Improving seed yield is always a major goal in soybean breeding programs. The economic performance of soybeans can be increased by using new and high-yield varieties. …”
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Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis by Mahnoor Mir, Felipe Soto, Pedro Antonio Amezcua Gomez, Rodrigo Del Rio Arroyo, Adarsh Suresh, Amber Su, Qiong Gan, John Stewart, Roberto Adachi, Diwakar D. Balachandran, Lara Bashoura, Roberto F. Casal, Burton F. Dickey, George A. Eapen, Scott E. Evans, Horiana Grosu, Carlos A. Jimenez, Julie Lin, David E. Ost, Bruce F. Sabath, Vickie R. Shannon, Aung Naing, Jianjun Gao, Jia Wu, Karthik Suresh, Saadia A. Faiz, Mehmet Altan, Ajay Sheshadri

“…In patients with pneumonitis, lymphocyte percentage (HR 0.99, 95% CI 0.97–1.00, p = 0.02), neutrophil percentage (HR 1.01, 95% CI 1.00–1.02, p = 0.05), and eosinophil percentage (HR 0.93, 95% CI 0.86–0.99, p = 0.03) were associated with 1-year survival.ConclusionBAL lymphocytosis and eosinophilia are associated with ICIP, but their ability to discriminate ICIP from other conditions is modest. BAL immune cell percentages may have prognostic value for 1-year survival, but this likely reflects the morbidity of other pulmonary diseases that require BAL for evaluation.…”
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Integrating Gut Microbiome and Metabolomics with Magnetic Resonance Enterography to Advance Bowel Damage Prediction in Crohn’s Disease by Huang L, Meng J, Lin S, Peng Z, Zhang R, Shen X, Zheng W, Zheng Q, Wu L, Wang X, Wang Y, Mao R, Sun C, Li X, Feng ST

“…The optimal Xtreme Gradient Boosting Classifier (XGBC) model integrating three microbial genera, six fecal metabolites, three serum metabolites, and three MRE features achieved superior performance (AUC 0.857 and 0.829 in the derivation and external validation cohorts, respectively). …”
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Identifying and Validating Indicators of Ritualism in the Iranian Higher Education System: A Mixed-Methods Study by Seyed Hedayat Davarpanah, Reza Hoveida, Mostafa Bagherian Far

“…Data analysis for the quantitative phase was performed using Smart-PLS and SPSS 23 software. To establish the validity of the researcher-developed questionnaire, we assessed content, convergent, and discriminant validity. …”
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What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…The statistical models did not perform well enough to be used to guide decision-making. …”
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Analyzing the Reproductive Characteristics of the Naked Carp Gymnocypris Przewalskii (Kessler) Based on the Oxygen Isotopes of Otolith Core Using SHRIMP by Ling ZHOU, Linbo QIAN, Sumei ZHAO, Xiulan ZHANG, Yinglie LIU, Qiaoling TANG, Jie YUAN

“…The overall successful rate of discrimination was recorded to be 82.6% by cluster analysis. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…Researchers have no obligation to repair unjust conditions that they bear no responsibility for causing.…”
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NMR-based serum metabolomics in patients with low-differentiated serous ovarian cancer by Mateusz M. Klimek, Agnieszka Skorupa, Mateusz Ciszek, Tomasz Cichon, Bartosz Cichon, Lukasz Boguszewicz, Andrzej Witek, Maria Sokol

“…MATERIAL AND METHODS: We analyzed serum samples from 17 HGSOC patients and 14 control patients with benign gynecological conditions. Serum metabolites were profiled using 1H NMR spectroscopy, and multivariate data analyses, including Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA), were performed to identify discriminating metabolites. …”
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Recognition of Symbolic Gestures Using Depth Information by Hasan Mahmud, Md. Kamrul Hasan, Abdullah-Al-Tariq, Md. Hasanul Kabir, M. A. Mottalib

“…The gestures may be produced in different illumination conditions or occluding background scenarios. Any hand gesture recognition system should find enough discriminative features, such as hand-finger contextual information. …”
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Identification of Mine Water Source Based on AHP-Entropy and Set Pair Analysis by Xianming Zhao, Zhimin Xu, Yajun Sun

“…The results show that the SPA-based model performs better in identifying the groundwater sources. …”
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Recurrence Quantification Analysis of Center of Pressure Trajectories for Balance and Fall-Risk Assessment in Young and Older Adults by Emiliano Fernandez-Cervantes, Luis Montesinos, Andres Gonzalez-Nucamendi, Leandro Pecchia

“…This study aimed to determine the ability of recurrence quantification analysis (RQA) measures to characterize balance control during quiet standing in young and older adults and to discriminate between different fall risk groups. We analyze center pressure trajectories in the medial-lateral and anterior-posterior directions from a publicly available static posturography dataset that contains tests acquired under four vision-surface testing conditions. …”
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Diagnostics of Rotor Damages of Three-Phase Induction Motors Using Acoustic Signals and SMOFS-20-EXPANDED by Adam GLOWACZ

“…A classification step was performed using 3 classifiers: LDA (Linear Discriminant Analysis), NBC (Naive Bayes Classifier), CT (Classification Tree). …”
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Detection Storage Time of Mild Bruise’s Loquats Using Hyperspectral Imaging by Zhaoyang Han, Bin Li, Qiu Wang, Akun Yang, Yande Liu

“…Due to the fact that the color features can be used to perform the conditions of the darkened and brownish regions in bruise’s loquats, the combined spectral information and the color features method is proposed to accurately detect the storage time of mild bruise’s loquats in this study. …”
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Vaginal Microbiota Changes in the Vulvar Lichen Simplex Chronicus by Ling Mei, Dongmei Wei, Yueyue Chen, Yueting Zhang, Tao Cui, Jian Meng, Xiaoli Zhang, Yuqing Liu, Lisha Ding, Qian Wang, Tao Wang, Xiaoyu Niu

“…Background: The vulvar lichen simplex chronicus (VLSC) is a common condition in gynecologic clinics. Though VLSC is not life-threatening, it usually causes pruritus, soreness and dispareunia, which cause general discomfort. …”
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