Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosisResearch in context by Stylianos Papadopoulos, David Hardy, Frédérique Vernel-Pauillac, Magali Tichit, Ivo G. Boneca, Catherine Werts

“…The funders had no implication in the design, analysis and reporting of the study.…”
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Increased adverse pregnancy outcomes among decreased assisted reproductions during the COVID-19 pandemic: insights from a birth cohort study in Southwest China by Jinnuo Hu, Jiaxin Liu, Qin Zeng, Jiuzhi Zeng, Min Luo, Dan He, Yan Zhang, Piao Zhang, Juan Ming, Weixin Liu

“…For CAs, the rate difference increased from + 0.34% (P = 0.089) prior to the outbreak to + 0.59% (P = 0.102) at post-outbreak. In 2018 (pre-pandemic), ART was the most significant predictor of LBW, exhibiting an RR of 3.45 (95% CI: 2.57–4.53). …”
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Lung cancer-associated fibroblasts-mediated collagen deposition drives mediastinal lymph node metastasis in non-small cell lung cancer by Caoyang Chen, Caoyang Chen, Yuqian Feng, Yuqian Feng, Frankie Chi Fat Ko, Sze Kwan Lam, Sheng Yan, James Chung Man Ho

“…Fibrillar collagen deposition within the TME was quantified using picrosirius red staining (PRS).ResultsActivation of α-SMA, accompanied by a significant increase in Col 1A1 expression in MRC-5 cells, was successfully induced through a direct 14-day co-culture with NSCLC cell lines. Histological analysis revealed increased fibrotic tissue formation, enhanced fibrillar collagen deposition, peritumoral lymphangiogenesis, and mediastinal lymph node metastasis in CAFs-enriched orthotopic xenograft (OX) tumors compared to CAFs-devoid OX tumors. …”
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BRAF inhibitor resistance of melanoma cells triggers increased susceptibility to natural killer cell-mediated lysis by Antoine Toubert, Eric Pasmant, Alexandra Frazao, Louise Rethacker, Géraldine Jeudy, Marina Colombo, Marie-Françoise Avril, Helene Moins-Teisserenc, Marie Roelens, Sophie Dalac, Eve Maubec, Anne Caignard

“…We determined the levels of several soluble molecules including NK ligands in 61 melanoma patients at baseline and 6 months M post-treatment with targeted therapies or immunotherapies.Results Vemurafenib resistance involved activation of p-AKT in SK28R and of p-MEK/p-ERK in M14R cells and was accompanied by modulation of NK ligands. …”
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Echocardiographic evaluation of myocardial structural and functional changes in patients with stage 5 chronic kidney disease before and after kidney transplantation by M. Sh. Khubutiya, E. V. Shuvalova, O. N. Rzhevskaya, L. T. Khamidova, A. A. Ivannikov, Kh. G. Alidzhanova, A. G. Balkarov, I. V. Dmitriev

“…It was found that after 3 months post kidney transplantation, there was a decrease in the left atrium diameter, volume, and volume index. …”
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Characterization of SARS‐CoV‐2 Entry Genes in Skeletal Muscle and Impacts of In Vitro Versus In Vivo Infection by Salyan Bhattarai, Eva Kaufmann, Feng Liang, Yumin Zheng, Ekaterina Gusev, Qutayba Hamid, Jun Ding, Maziar Divangahi, Basil J. Petrof

“…In vivo, the diaphragm and quadriceps of Roborovski hamsters with SARS‐CoV‐2 respiratory infection were examined at day 3 post‐inoculation to evaluate the relationship between atrophy pathway and SARS‐CoV‐2 transcripts by qPCR, as well as histological measurements of myofibre morphology. …”
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A Randomized Controlled Trial of a Biodegradable Polymer, Microcrystalline Sirolimus-Eluting Stent (MiStent) versus Another Biodegradable Polymer Sirolimus-Eluting Stent (TIVOLI):... by Bin Wang, Sicong Ma, Zhiyong Wang, Li Zhang, Hanjun Pei, Yang Zheng, Yuejin Yang, Zheng Zhang, Xinqun Hu, Ziwen Ren, Feng Zhang, Changqian Wang, Renqiang Yang, Zhiming Yang, Yuexi Wang, Guosheng Fu, Yu Cao, Zuyi Yuan, Kai Xu, Xin Zhao, Bo Xu, Miaohan Qiu, Quanmin Jing

“…Objective:. Data comparing the outcomes of MiStent (Micell Technologies, Durham, North Carolina, USA) microcrystalline biodegradable polymer (BP) drug-eluting stent (DES) and those of another post-marketing BP-DES, TIVOLI (EssenTech, Beijing, China) are rare. …”
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Dysregulated monocyte compartment in PACS patients by Romy Kronstein-Wiedemann, Romy Kronstein-Wiedemann, Madeleine Teichert, Elisa Michel, Janina Berg, George Robinson, Kristin Tausche, Kristin Tausche, Martin Kolditz, Martin Kolditz, Johannes Bergleiter, Jessica Thiel, Jessica Thiel, Dirk Koschel, Dirk Koschel, Dirk Koschel, Stephan R. Künzel, Stephan R. Künzel, Kristina Hölig, Kristina Hölig, Kristina Hölig, Torsten Tonn, Torsten Tonn, Torsten Tonn, Manuela Rossol, Manuela Rossol

“…We performed blood gas analysis and measured hematological parameters from peripheral blood of PACS patients and compared them with healthy donors. …”
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Daily Mobility in Metropolitan Areas by Marcela Soto Caro

“…Running counter to this socially polarised outward flow, characteristic of neoliberal economic policies and post-Fordist processes, there are signs of a returning flow towards the historic centre. …”
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Preoperative Mechanical Ventilation Prior to Surgical Repair for Type A Aortic Dissection: Incidence, Risk, and Outcomes by Angelo M. Dell’Aquila, Konrad Wisniewski, Adrian-Iustin Georgevici, Gábor Szabó, Francesco Onorati, Till J. Demal, Andreas Rukosujew, Sven Peterss, Caroline Radner, Joscha Buech, Antonio Fiore, Andrea Perrotti, Angel G. Pinto, Javier Rodriguez Lega, Marek Pol, Petr Kacer, Enzo Mazzaro, Giuseppe Gatti, Igor Vendramin, Daniela Piani, Luisa Ferrante, Mauro Rinaldi, Eduard Quintana, Robert Pruna-Guillen, Dario Di Perna, Zein El-Dean, Hiwa Sherzad, Giovanni Mariscalco, Mark Field, Amer Harky, Manoj Kuduvalli, Matteo Pettinari, Stefano Rosato, Tatu Juvonen, Timo Mäkikallio, Lenard Conradi, Giorgio Mastroiacovo, Fausto Biancari

“…The in-hospital mortality rate among IMV patients was 38% vs. 15% in non-IMV patients (<i>p</i> < 0.001), without a difference in post-discharge survival (<i>p</i> = 0.84). At the MMLR, patients who required IMV had 135% higher odds of in-hospital death compared to the remaining patients. …”
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Effect of inhibition of reactivated alcohol-associated memories with propranolol on alcohol craving by Shuai Yu, Peng-Jiao Xu, Le Shi, Xiao-Yang Zhang, Chuan-Sheng Wang, Fang Wu, Xiao Li, Ping Cui, Rui-Ling Zhang, Lin Lu, Ya-hui Xu

“…The systolic blood pressure, diastolic blood pressure, and heartrate were applied to evaluate cue responsiveness. Repeated measures analysis of variance was used to compare the craving degree and independent samples t-tests were used for comparing demographic characteristics, scale scores between alcohol-dependent patient groups, and pre-post differences in heart rate, systolic blood pressure, and diastolic blood pressure at each experimental phase. …”
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Effect of Brassinosteroid and Melatonin Foliar Application on Biochemical Characteristics and Growth Indices of Quinoa (Chenopodium quinoa Willd) under Drought Stress Condition by N Pakgohar, A. A Maghsoudi Mood, H Farahbakhsh, A Pasandi pour

“…Both brassinosteroid and melatonin applications reduced chlorophyll fluorescence under mild and severe drought stress compared to controls. Soluble carbohydrates content increased by 50.4% at 50% field capacity irrigation compared to normal irrigation. …”
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Multi-Level Intertemporal Attention-Guided Network for Change Detection in Remote Sensing Images by Shuo Liu, Qinyu Zhang, Yuhang Zhang, Xiaochen Niu, Wuxia Zhang, Fei Xie

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Predictors and Outcomes of Excellent Recanalization Versus Successful Recanalization After Thrombectomy in Proximal and Distal Medium Vessel Occlusion Strokes: A Multinational Stud... by Vivek Yedavalli, Hamza Adel Salim, Basel Musmar, Nimer Adeeb, Kareem El Naamani, Nils Henninger, Sri Hari Sundararajan, Anna Luisa Kühn, Jane Khalife, Sherief Ghozy, Luca Scarcia, Benjamin Y. Q. Tan, Jeremy J. Heit, Robert W. Regenhardt, Nicole M. Cancelliere, Joshua D. Bernstock, Aymeric Rouchaud, Jens Fiehler, Sunil Sheth, Muhammed Amir Essibayi, Ajit S. Puri, Christian Dyzmann, Marco Colasurdo, Xavier Barreau, Leonardo Renieri, João Pedro Filipe, Pablo Harker, Răzvan Alexandru Radu, Mohamad Abdalkader, Piers Klein, Thomas R. Marotta, Julian Spears, Takahiro Ota, Ashkan Mowla, Pascal Jabbour, Arundhati Biswas, Frédéric Clarençon, James E. Siegler, Thanh N. Nguyen, Ricardo Varela, Amanda Baker, David Altschul, Nestor R. Gonzalez, Markus A. Möhlenbruch, Vincent Costalat, Benjamin Gory, Christian Paul Stracke, Mohammad Ali Aziz‐Sultan, Constantin Hecker, Hamza Shaikh, David S. Liebeskind, Alessandro Pedicelli, Andrea M. Alexandre, Illario Tancredi, Tobias D. Faizy, Erwah Kalsoum, Boris Lubicz, Aman B. Patel, Vitor Mendes Pereira, Adrien Guenego, Adam A. Dmytriw

“…Conclusion This study underscores that among patients with MeVO stroke with successful recanalization (mTICI 2b–3) there is higher likelihood of achieving excellent recanalization (mTICI 2c–3) in distal occlusions and cardioembolic pathogenesis. mTICI 2c–3 scores post‐MT correlate with improved clinical outcomes compared with mTICI 2b, affirming the superiority of excellent recanalization over successful recanalization in patients with MeVO stroke. …”
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TLS and immune cell profiling: immunomodulatory effects of immunochemotherapy on tumor microenvironment in resectable stage III NSCLC by Chaopin Yang, Chaopin Yang, Jinqi You, Jinqi You, Yizhi Wang, Yizhi Wang, Si Chen, Si Chen, Yan Tang, Yan Tang, Hao Chen, Hao Chen, Haoran Zhong, Ruyue Song, Hao Long, Hao Long, Tong Xiang, Ze-Rui Zhao, Ze-Rui Zhao, Jianchuan Xia, Jianchuan Xia

“…Spatial analysis revealed variations in the distance between PD-L1+CD11c+ cells and PD1+CD8+ T cells within TLSs in the immunochemotherapy group. …”
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Failure Risk Investigation of Transmission Tower-line System Under Sequential Earthquake Considering Input Directionality by LIU Juncai, DONG You

“…A nonlinear hysteretic model is employed to mimic the complex mechanical behavior of steel members, encompassing buckling and post-buckling phenomena, as well as the degradation of strength and stiffness. …”
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Undertriage in geriatric trauma: insights from a multicentre cohort study by Daniel Anthony Koch, Lars Becker, Uwe Schweigkofler, Paul Hagebusch, Philipp Faul, Christian Waydhas, Florian Pavlu, Markus Baacke, Caspers Michael, Valentin Clemens, Helena Duesing, Matthias Froehlich, Sebastian Imach, Kai-Oliver Jensen, Christian Kleber, Annette Keß, Gerrit Matthes, Andre Nohl, Orkun Oezkurtul, Thomas Paffrath, Vera Pedersen, Kai Sprengel, Philipp Stoermann, Heiko Trentzsch, Rolf Lefering, Dan Bieler, Lisa Hackenberg, The Committee on Emergency Medicine, Intensive Care and Trauma Management (Sektion NIS) of the German Trauma Society (DGU) Germany

“…Post-hoc analysis revealed that 53.8% of geriatric patients requiring trauma care were undertriaged. …”
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Adjuvant chemotherapy with S-1 after curative chemoradiotherapy in patients with locoregionally advanced squamous cell carcinoma of the head and neck: Reanalysis of the ACTS-HNC st... by Akira Kubota, Eiji Nakatani, Kiyoaki Tsukahara, Yasuhisa Hasegawa, Hideki Takemura, Tomonori Terada, Takahide Taguchi, Kunihiko Nagahara, Hiroaki Nakatani, Kunitoshi Yoshino, Yuichiro Higaki, Shigemichi Iwae, Takeshi Beppu, Yutaka Hanamure, Kichinobu Tomita, Naoyuki Kohno, Kazuyoshi Kawabata, Satoshi Teramukai, Masato Fujii, ACTS-HNC Study Group

“…ACTS HNC study showed the significant efficacy of S-1 after curative radiotherapy in sub-analysis. We explored the efficacy of S-1 after curative CRT in a subset of patients from the ACTS-HNC study.…”
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Вплив удобрення на формуванняпродуктивності ячменю ярого в короткоротаційних сівозмінах by Марія ЩЕРБА, Оксана КАЧМАР, Ангеліна ДУБИЦЬКА, Оксана ВАВРИНОВИЧ, Оксана ТАРАВСЬКА

“…The use of intensive (manure + mineral fertilizers) and alternative (green mass of post-harvest oil radish + precursor by-products + mineral fertilizers) fertilization systems restrained the compaction process and provided 4.46–2.65 % lower values of capacity after winter wheat and by 3.5– 1.72 % after potatoes compared to the control without fertilizer. …”
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HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in... by Augustine T Choko, Elizabeth L Corbett, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Cheryl C Johnson, Doreen Sakala, Thokozani Kalua, Moses Kumwenda, Richard Hayes, Katherine Fielding

“…Measurement of linkage to post-test services following HIVST remains the biggest challenge, yet is the biggest driver of cost-effectiveness. …”
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