SURVIVAL OUTCOMES OF AUTOLOGOUS STEM CELL TRANSPLANTATION IN LYMPHOMA PATIENTS by Elif Yıldız, Güven Çetin, Özge Pasin

“…Only patients who followed up at least 12 months after the ASCT were included for analysis. For survival analysis, research will evaluate overall survival (OS) and progression-free survival (PFS). …”
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Low-added sugar dietary intervention study to mitigate glucose intolerance and improve body composition in adults with cystic fibrosis: a protocol of a double-blind, randomised stu... by Priyathama Vellanki, Kirk Easley, Terryl J Hartman, Thomas R Ziegler, Puneet Sharma, Swati Zaveri, Arlene Stecenko, William R Hunt, Amy Goss, Joshua D Chandler, Tasha M Burley, Chris Driggers, Amy Ciccarella, Heather Zhou, Kristen Narlow, Tanicia Daley, Jessica Alvarez

“…., sugar not naturally occurring in foods) has been shown to be increased in PwCF and this excess intake of added sugar could increase the risk of CFRD.Methods and analysis/design The goal of this ongoing double-blind, randomised, parallel-group clinical trial is to recruit approximately 60 clinically stable adults with CF to determine if a low-added sugar intervention improves beta-cell responsiveness and insulin sensitivity (Aim 1), reduces visceral adipose tissue (VAT) and other ectopic fat deposition (Aim 2) and improves plasma redox status (Aim 3) over 8 weeks compared with a typical CF diet. …”
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Reduced morbidity and mortality of cGVHD in patients who received treatment with mesenchymal stromal cells for steroid-resistant aGVHD: long-term follow-up of a randomized phase 3... by Ke Zhao, Ren Lin, Zhiping Fan, Zhen Li, Xiaoyong Chen, Li Xuan, Fen Huang, Na Xu, Xiuli Wu, Shaohua Chen, Jing Sun, Xi Zhang, Jianyu Weng, Yonghua Li, Yuhua Li, Dongjun Lin, Danian Nie, Shunqing Wang, Xiaojun Xu, Xiaohui Zhang, Yangqiu Li, AP Xiang, Yu Wang, Qifa Liu

“…Abstract Background Our open-label, multicenter, randomized, phase 3 trial showed that the incidence and severity of chronic graft-versus-host disease (cGVHD) reduced in steroid-resistant acute graft-versus-host disease (aGVHD) patients who underwent mesenchymal stromal cells (MSCs) treatments, but survival benefit was not received. Here, we present a post-hoc analysis of the 5-year follow-up to explore long-term survival and its underlying mechanism. …”
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Impact of COVID-19 Vaccination on Cardiac Function and Survival in Maintenance Hemodialysis Patients by Xiao Tu, Tingfei He, Bing Xu, Jiazhen Yin, Fangyu Yi, Ye Li, Jinchi Gao, Peng Bi, Wanyue Xu, Rihong Hu, Lidan Hu, Yayu Li

“…We compared the pre- and post-infection changes in heart function (echocardiographic parameters) and BNP levels between the two groups and assessed their association with the survival rates. …”
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Investigation on the motion and fragmentation mechanism of rockfall based on PIV-seismic signal monitoring by Sui Zhende, Zhang Ke, Zhang Kai, Lin Qibin

“…This correlation helps delineate the fragmentation degree and kinematic state of rockfall debris, offering valuable references for the development of monitoring strategies within early warning systems. Compared to traditional monitoring methods focused solely on amplitude, this spectral analysis approach provides a more refined representation of the fragmentation state and changes in movement modality during rockfall. …”
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Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity by Pereira AP, Janela D, Areias AC, Molinos M, Tong X, Bento V, Yanamadala V, Cohen SP, Correia FD, Costa F

“…The rising prevalence of obesity calls for scalable solutions to address MSK conditions in this population, given their complex clinical profile and barriers to accessing care.Purpose: To evaluate the engagement and clinical outcomes of a fully remote digital care program in patients with MSK conditions, focusing on those with and without comorbid obesity.Patients and Methods: A post-hoc analysis of a prospective, longitudinal, single-arm observational home-based study conducted between August, 2023, and August, 2024. …”
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Modified Rankin Scale at 90 Days Versus National Institutes of Health Stroke Scale at 24 Hours as Primary Outcome in Acute Stroke Trials by Johanna M. Ospel, Scott Brown, Salome Bosshart, Alexander Stebner, Kazutaka Uchida, Andrew Demchuk, Jeffrey L. Saver, Philip White, Keith W. Muir, Diederik W. J. Dippel, Charles B. L. M. Majoie, Tudor G. Jovin, Bruce C. V. Campbell, Peter J. Mitchell, Serge Bracard, Francis Guillemin, Michael Hill, Mayank Goyal

“…Background We investigate whether the National Institutes of Health Stroke Scale (NIHSS) at 24 hours could serve as a primary outcome in acute ischemic stroke trials, and whether combining 90‐day modified Rankin Scale (mRS) and 24‐hour NIHSS in a hierarchical outcome could enhance detection of treatment effect, using endovascular treatment (EVT) as an exemplary study intervention. Methods This was a post hoc analysis of pooled data from 7 randomized EVT trials. …”
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Melatonin Implantation Improves the Reproductive Performance of Estrus-Synchronized Ewes During Seasonal Anestrus and Enhances the Antioxidant and Steroidogenic Capacities of Granu... by Zengyi Duan, Menghao Liu, Junjin Li, Kexiong Liu, Qi Qi, Zhixuan Yu, Hadia Akber Samoo, Chunxin Wang, Jian Hou

“…Ovarian transcriptome analysis revealed 522 differentially expressed genes (DEGs) in the MT group compared with the CON group, including 355 upregulated and 167 downregulated DEGs. …”
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The promoting effects of digital targeted cognitive training in medication treatment for children with ADHD: a randomized controlled trial by Chen Dang, Yu Zhu, Xiangsheng Luo, Lu Liu, Yuan Feng, Guisen Wu, Shaogen Zhong, Xin Wang, Jianzhao Zhang, Yike Zhu, Siqi Liu, Ziqi Liu, Li Qin, Xiaohui Ma, Yufeng Wang, Xiaoyi Wang, Jian Yang, Changming Wang, Li Sun

“…Post-hoc exploratory analysis results: (1) In patients who received ATX treatment, TCT + ATX led to greater improvement in ADHD-RS total, inattention, and hyperactivity/impulsivity symptoms. …”
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Abstract 067: Outcomes for large vessel occlusion patients with severe baseline disability with and without endovascular thrombectomy by Amine J. Awad, Michael J. Young, Alexander Andreev, Adam A. Dmytriw, Justin E. Vranic, James D. Rabinov, Christopher J. Stapleton, Alvin S. Das, Anna K. Bonkhoff, Lara Carvalho de Oliveira, Markus D. Schirmer, Thabele M. Leslie‐Mazwi, Aneesh B. Singhal, Aman B. Patel, Natalia S. Rost, Robert R. Regenhardt

“…Conclusion Among patients with severe baseline disability, EVT is associated with less post‐stroke accumulated disability without limiting transitions to comfort care. …”
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The efficacy and safety of remimazolam for the management of emergence agitation: a randomized, double-blind, placebo-controlled study by Xiaoxing Lu, Xiaoxing Lu, Meiyan Zhou, Yao Lu, Yao Lu, Jia Sun, Kexin Mao, Yangzi Zhu, Yangzi Zhu, Rongguo Wang, Yong Cao, Liwei Wang, Liwei Wang, Liwei Wang

“…Secondary outcomes included rescue propofol dosage, EA duration, and the post-anesthesia care unit (PACU) discharge time. …”
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Prognostic effect of body mass index in patients with acute leukemia undergoing allogeneic hematopoietic stem cell transplantation: A retrospective cohort study by Jing Yu, Zhuoyue Shi, Hengwei Wu, Yi Luo, Jian Yu, Yamin Tan, Xiaoyu Lai, Lizhen Liu, Huarui Fu, Yishan Ye, Luxin Yang, Congxiao Zhang, He Huang, Jimin Shi, Yanmin Zhao

“…To elucidate the influence of pretransplant BMI on post-allo-HSCT outcomes including graft-versus-host disease (GVHD), overall survival (OS), relapse-free survival (RFS), and nonrelapse mortality (NRM), we conducted a retrospective study using registry data which comprised 1092 adult patients who underwent allo-HSCT between 2015 and 2023. …”
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Comparison of Left Ventricular Global Longitudinal Strain and Left Ventricular Ejection Fraction in Acute Respiratory Failure Patients Requiring Invasive Mechanical Ventilation by Zubair Bashir, Feven Ataklte, Shuyuan Wang, Edward W. Chen, Vishnu Kadiyala, Charles F. Sherrod, Phinnara Has, Christopher Song, Corey E. Ventetuolo, James Simmons, Philip Haines

“…This suggests an association between IMV and lower LVGLS in ARF patients requiring IMV, indicating that LVGLS may be a more sensitive marker for detecting subclinical LV dysfunction compared to LVEF in this population. Future studies should track and assess serial echocardiography data in the same cohort of patients pre-, during, and post-IMV in order to validate these findings and prognosticate STE-detected LV dysfunction in ARF patients requiring IMV.…”
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Short-Term Effects of a Snack Including Fruit Juice Enriched with Vitamin D3, n-3 Fatty Acids, and Probiotics on Energy Intake and Satiety in Normal-Weight and Overweight Individua... by Christina Athanasaki, Nikolaos Zacharodimos, Sofia Tsitsou, Dionysia-Lydia Bothou, Stamatia Vitsou-Anastasiou, Olga S. Papadopoulou, Emilia Papakonstantinou

“…Additionally, the overweight individuals had a lower total energy intake at the meal and a lower energy intake 24 h post intervention day, as well as lower protein and fat intakes, compared to the normal-weight individuals. …”
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The impact of early vs. delayed surgery on outcomes in cervical spinal cord injury without fracture or dislocation by Sirui Xiao, Hui Yan, Beixi Bao, Yuxuan Wu, Xiaokang Cheng, Chunyang Xu, Jiaguang Tang

“…Intergroup comparisons were also made regarding hospitalization duration, time to return to work post-discharge, in-hospital treatment costs, and patient satisfaction 2 years after treatment.ResultsMSCC showed a significant positive correlation with postoperative neurological recovery metrics including RR, JOA, AMS, and AMSRR, while its correlation with ASSRR was weaker. …”
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Anti-Tyrosinase and Radical Scavenging Activities of Selected Cassipourea Plants and Isolated 7-Methoxygeranin A: Traditional Use as Skin Lighteners by Mpofana N, Paulse M, Yalo M, Dlova NC, Hussein A, Lanrewaju AA, Lukman HY, Aribisala JO, Rautenbach F, Marnewick JL, Sabiu S

“…Statistical analyses, including ANOVA and post-hoc tests, compared extract activities.Results: C. flanaganii exhibited the most potent anti-tyrosinase activity (IC50: 37.10 μg/mL), though statistical differences among species were non-significant. …”
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Chicken liver and eggshell crackers are a safe and affordable animal source food for overcoming micronutrient deficits during pregnancy and lactation in Indonesia: a double-blind,... by Aly Diana, Sofa Rahmannia, Yenni Zuhairini Suhadi, Dimas Erlangga Luftimas, Haidar Rizqi, Afini Dwi Purnamasari, Ayunda Jihadillah, Mohammad Brachim Ansari, Dearly Ayu Zahrotun Haq, Aisyah Nur Pratiwi, Dina Novtyana Puspita, Yeni Intan Kusuma Dewi Affandy, Christopher M. A. Frampton, Umi Fahmida, Lisa A. Houghton, Rosalind S. Gibson

“…Individual mother-infant dyads were the unit of analysis. Primary outcomes were birth length (cm), attained length (cm), LAZ-score, and length velocity (cm/month) from birth to five months postpartum. …”
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The association between vision impairment and multi-site pain in middle-aged and older adults in China: results from the China health and retirement longitudinal study by Tianyi Luo, Cunzi Li, Lan Zhou, Lan Zhou, Yingrui Liu, Hongyan Sun, Ming Ming Yang

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Hybrid-J shape needle in ultrasound-guided looped thread carpal tunnel release: a cadaveric study on safety and efficacy by Lin Jiasen, Li Yuxiang, Jiang Liang, Long Yi, Li Honglve, Wang Yongbo, Geng Weikuan, Deng Xinghao, Zhang Congda, Yang Rui, Hou Jingyi

“…Intraoperative structural damage such as nerve, blood vessel and tendon were assessed by blinded observer and anatomist. Post-procedural dissection confirmed transverse carpal ligament (TCL) transection completeness. …”
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Scapular dyskinesis-based exercise therapy versus multimodal physical therapy for subacromial impingement syndrome in young overhead athletes with scapular dyskinesis: a randomized... by Meilin Wen, Xuanming Hu, Guiying Bao

“…Although registration occurred post-enrolment, the study protocol was finalized and ethically approved prior to participant recruitment. …”
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