Lung Transplantation Outcomes and Peritransplant Sirolimus Use in Lymphangioleiomyomatosis by Emily L. Larson, BS, Reed T. Jenkins, BA, Jessica M. Ruck, MD, Laura B. Zeiser, MS, Alice L. Zhou, MS, Alfred J. Casillan, MD, PhD, Dorry L. Segev, MD, Allan B. Massie, MD, Jinny S. Ha, MD, Pali D. Shah, MD, Christian A. Merlo, MD, MPH, Errol L. Bush, MD

“…A pharmacy claims database was linked to provide sirolimus prescription information, and a subgroup analysis comparing outcomes with pre- vs posttransplant sirolimus use was performed. …”
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In Vivo Evaluation of the Anti-Skin-Ageing Bioactivity of a Recombinant Dual Humanised Collagen and Poly-L-Lactic Acid by Mingjie Tong, Xin Zhou, Jiongni Zhong, Dengjian Qu, Wei Chen, Chun Chen, Yiting Wang, Yaoping Liu, Shaochuan Li, Yuan Xiao, Ning Wang, Chaowan Guo, Qiuling Xie, Sheng Xiong

“…Histological analysis revealed 23.4% greater dermal thickness in DuCol-treated groups compared to PLLA at 90 days. …”
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Effect of Platelet-rich Fibrin on Soft-tissue and Hard-tissue Healing following Surgical Extraction of Mandibular Third Molar: A Prospective Interventional Study by Sudip Chakraborty, Chayan Kundu, Samiran Ghosh, Richi Burman, Avishek De Sarkar, Gourab Mandal, Somak Saha

“…The corrected Chi-square test of independence was performed to compare soft-tissue healing. A highly significant association was found on the 3rd postoperative day (p-value=0.03), 14th postoperative day (p-value=0.013), and 28th postoperative day (p-value=0.002), indicating that group I consistently demonstrated improved healing compared to group II. …”
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Integrating killer cell immunoglobulin-like receptor high-resolution genotyping for predicting transplant outcomes in allogeneic hematopoietic stem cell transplantation by Antonia Schäfer, Stéphane Buhler, Ticiana D.J. Farias, Katherine M. Kichula, Helen Baldomero, Zuleika Calderin Sollet, Sylvie Ferrari-Lacraz, Baptiste Micheli, Stavroula Masouridi-Levrat, Vanessa Mesquita, Oliver Kürsteiner, Gayathri Nair, Jörg Halter, Tayfun Güngör, Dominik Schneidawind, Yves Chalandon, Jakob R. Passweg, Paul J. Norman, Jean Villard

“…Highly inhibiting KIR3DL1 – HLA-B and HLA-A (Bw4) interactions were associated with a reduced relapse incidence as compared to weak and non-inhibiting interactions. Our study indicates that high-resolution KIR genotyping informs post-transplant outcomes with a seemingly higher protection of educated NK cells. …”
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Canadian Highly Sensitized Patient Program Report: A 1000 Kidney Transplants Story by M. Khaled Shamseddin, Steven Paraskevas, Rahul Mainra, Kyle Maru, Bailey Piggott, Darlene Jagusic, Kathy Yetzer, Lakshman Gunaratnam, Christine Ribic, Joseph Kim, Sunita Singh, Stephanie Hoar, G. V. Ramesh Prasad, Melanie Masse, Isabelle Houde, Myriam Khalili, Kenneth West, Rob Liwski, Sean Martin, Nessa Gogan, Martin Karpinski, Mauricio Monroy-Cuadros, Sita Gourishankar, Olwyn Johnston, James Lan, Christopher Nguen, John Gill, Michel Pâquet

“…Purpose: Highly sensitized patients (HSPs) with kidney failure have limited access to kidney transplantation and poorer post-transplant outcomes. Prioritizing HSPs in kidney allocation systems and expanding the pool of deceased donors available to them has helped to reduce their wait times for transplant and enhanced post-transplant outcomes. …”
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Association between dietary antioxidants, serum albumin/globulin ratio and quality of life in esophageal squamous cell carcinoma patients: a 7-year follow-up study by Juwei Zhang, Jinsong Zhou, Siting Chen, Yue Huang, Zheng Lin, Yuan Deng, Minglian Qiu, Zhisheng Xiang, Zhijian Hu, Zhijian Hu

“…HRQOL was assessed over 7 years post-surgery via telephone follow-up and analyzed longitudinally using a time to deterioration (TTD) model. …”
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Antibiotics combined with vaginal probiotics in the embryo transfer cycle of infertile patients with chronic endometritis by Ping Hu, Ping Hu, Mengyue Chen, Mengyue Chen, Lu Zhu, Lu Zhu, Bing Song, Chao Wang, Xiaojin He, Xiaojin He, Guanjian Li, Guanjian Li, Yunxia Cao, Yunxia Cao

“…The general characteristics and pregnancy outcomes of the first FET cycle post-treatment were compared between the two groups.ResultsThere were no statistically significant differences between the two groups in terms of general characteristics, clinical pregnancy rate, early miscarriage rate, and ectopic pregnancy rate. …”
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Effect of Er:YAG laser bone bed milling, with or without photobiomodulation, on the bone repair process of additive manufacturing implants in rats by Fernando Costa Neto, Isadora Breseghello, Laura Vidoto Paludetto, Sabrina Cruz Tfaile Frasnelli, Fábio Roberto de Souza Batista, Alberto Blay, Armando Boni, Fernando Costa Júnior, Roberta Okamoto

“…Data were analyzed using the Shapiro-Wilk test, followed by one-way ANOVA and Tukey's post hoc test, where applicable, with a significance level of p ≤ 0.05. …”
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Adjunctive use of p16 immunohistochemistry for optimizing management of CIN lesions in a high‐risk human papillomavirus‐positive population by Renée M. F. Ebisch, L. Lucia Rijstenberg, Gilda Ghazi Soltani, Judith van derHorst, Judith E. M. Vedder, Meyke Hermsen, Remko P. Bosgraaf, Leon F. A. G. Massuger, Chris J. L. M. Meijer, Daniëlle A. M. Heideman, Folkert J. vanKemenade, Willem J. G. Melchers, Ruud L. M. Bekkers, Albert G. Siebers, Johan Bulten

“…Material and methods In this post‐hoc analysis, 326 histology follow‐up samples from a group of hrHPV‐positive women were stained with p16 immunohistochemistry. …”
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The role of ultra-high field MRI and image processing in the presurgical workup in MRI-negative focal epilepsy: A validated 7T MRI case study by Daniel Uher, Gerhard S. Drenthen, Christianne M. Hoeberigs, Rick H.G.J. van Lanen, Albert J. Colon, Roy A.M. Haast, Vivianne H.J.M. van Kranen-Mastenbroek, Guido Widman, Paul A.M. Hofman, Louis G. Wagner, Jan C. Beckervordersandforth, Jacobus F.A. Jansen, Olaf E.M.G. Schijns, Walter H. Backes

“…Morphometric Analysis Program (MAP18) detected abnormalities on both 3 T and 7 T images. …”
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Implementing a pharmacogenetic-driven algorithm to guide dual antiplatelet therapy (DAPT) in Caribbean Hispanics: protocol for a non-randomised clinical trial by Dagmar F Hernandez-Suarez, Kyle Melin, Frances Marin-Maldonado, Hector J Nunez, Ariel F Gonzalez, Lorena Gonzalez-Sepulveda, Sona Rivas-Tumanyan, Hetanshi Naik, Gualberto Ruaño, Stuart A Scott, Jorge Duconge

“…Given the paucity of clinical research on CYP2C19 and antiplatelet clinical outcomes in Hispanics, our study will test the safety and efficacy of a genetic-driven treatment algorithm to guide dual antiplatelet therapy (DAPT) in Caribbean Hispanics.Methods and analysis This is a multicentre, prospective, non-randomised clinical trial that proposes an assessment of pharmacogenomic-guided DAPT in post-PCI Caribbean Hispanic patients with ACS or CAD. …”
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An evidence-based tailored eHealth patient education tool for patients with knee osteoarthritis: A randomized controlled trial by Chong Li, Chuanmei Zhu, Kangping Song, Xiaona Xiang, Xiaoyi Wang, Jing Hu, Zhao Li, Yi Deng, Daoxin Jiang, Lixin Guo, Ting Ren, Luwen Zhu, Haibo Ai, Shaojun Zhang, Zhongliang Liu, Yonghong Yang, Siyi Zhu, Chengqi He

“…Measurements were taken at baseline, post-intervention (T1), 1-month (T2), 3-month (T3), and 6-month (T4) follow-up. …”
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The effect of chewing gum on postoperative ileus after laparotomy for gastroduodenal perforations: a randomized controlled trial by Joshua Muhumuza, Selamo F. Molen, Godefroy N. Bassara, Musa A. Waziri, Stephen M. Kithinji, Kiyaka M. Sonye, Mugisho M. Leocadie, ByaMungu P. Kagenderezo, Esperant T Tshimanga, Tatana M. Faustin, Herman Lule

“…The continuous variables were compared using the nonparametric Wilcoxon Rank sum (Mann-Whitney U) test while the categorical outcomes were compared using the chi-squared test in SPSS version 26. …”
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Timing of mechanical ventilation and its association with in-hospital outcomes in patients with cardiogenic shock following ST-elevation myocardial infarction: a multicentre observ... by Waleed AlHarbi, Mohammed Qutub, Prashanth Panduranga, Jassim Al Suwaidi, Wael Al Mahmeed, Hassan Khan, Sultan Alobaikan, Abdullah Alenezi, Mohammed AlShehri, Abdulrahman Arabi, Amin Daoulah, Awad Abdulrazaq AlQahtani, Zubair Shahid, Ahmed Jamjoom, Ahmed Elmahrouk, Abeer Said Mohamed Al Rawahi, Gladsy Selva Livingston, Ala’a Al-deen Tayseer Mousa, Hatem Aloui, Mubarak Aldossari, Nooraldaem Yousif, Husam Noor, Rajesh Rajan, Amr A Arafat, Omar Kanbr, Alsayed Almarghany, Mokhtar Kahin, Abdulwali Abohasan, Faisal Al Nasser, Badr Alzahrani, Alaa Aldossari, Taher Hassan, Mohammed Ali Balghith, Khalid Alshali, Amir Lotfi

“…Baseline characteristics were comparable across groups. Increased delay in MV was associated with a higher mortality risk during the first 60 min post-diagnosis, beyond which the risk plateaued. …”
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Intervention Strategies to Overcome HPV Vaccine Hesitancy Among Hispanic Immigrants in the USA: A Video-Based Approach by Isaiah Aduse-Poku, Diego A. Ardon, Alexis B. Call, Spencer C. Davis, Preston Evans, Spencer Johanson, Ruth J. Larson, James Rencher, Isaac A. Woolley, Brian D. Poole, Jamie L. Jensen

“…Notably, females exhibited less favorable post-intervention attitudes compared to males. Additionally, perceived care from video creators was a strong predictor of normalized gains in vaccine attitudes (β = 0.270, <i>p</i> < 0.001). …”
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Severe Acute Respiratory Syndrome Coronavirus 2 Variant Infection Dynamics and Pathogenesis in Transgenic K18-h<i>ACE2</i> and Inbred Immunocompetent C57BL/6J Mice by Hongwei Liu, Brianna M. Ramirez, Talia S. Wong, Christopher M. Weiss, Kevin C. K. Lloyd, Qizhi Gong, Lark L. Coffey

“…These findings demonstrate contrasting phenotypes across the two models and reduced tropism and pathology of omicron compared to earlier variants in both models. This comprehensive analysis of SARS-CoV-2 variants in two mouse models provides valuable insights for model and variant selection for future studies.…”
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α-Synuclein orchestrates Th17 responses as antigen and adjuvant in Parkinson’s disease by Emi Furusawa-Nishii, Bataa Solongo, Kou Rai, Soichiro Yoshikawa, Asako Chiba, Ayami Okuzumi, Shin-ichi Ueno, Yasunobu Hoshino, Yoko Imamichi-Tatano, Haruka Kimura, Taku Hatano, Nobutaka Hattori, Sachiko Miyake

“…Peripheral blood mononuclear cells (PBMCs) from synucleinopathy patients and healthy controls were cultured in the presence of the αS peptide pools. Cytokine analysis using culture supernatants revealed that C-terminal αS peptides with a phosphorylated serine 129 residue (pS129), a feature of pathological αS aggregates, promoted the production of IL-17A, IL-17F, IL-22, IFN-γ and IL-13 in PD patients compared with that in controls. …”
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Efficacy of Intrathecal 0.75% Hyperbaric Ropivacaine versus 0.5% Hyperbaric Bupivacaine for Elective Inguinal and Perineal Surgery: A Randomised Double-blinded Clinical Study by Bhavini Shah, Dipanjali Mahanta

“…The time taken for the passage of first micturition post-subarachnoid block was earlier (338.73±31.29 min) in ropivacaine group. …”
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Joint association of the triglyceride–glucose index and stress hyperglycemia ratio with incidence and mortality risks of new-onset atrial fibrillation during sepsis: a retrospectiv... by Zhihong Zuo, Zijing Zhou, Qiang Liu, Ruizheng Shi, Ting Wu

“…Machine learning approach also was constructed to evaluate and compare the indices in predicting mortality risks. …”
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Does initiating care in alternate care sites decrease time to disposition in the emergency department? by Alyssa Mangino, Lakshman Balaji, Bryan Stenson, Larry A. Nathanson, David Chiu, Shamai A. Grossman

“…Door‐to‐disposition time (DTD) was calculated by identifying the time when the patient entered the ED and the time when disposition was decided (admission requested or patient discharged). Using regression analysis, we compared the two data sets to determine significant differences among DTD time. …”
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