Alterations in blood pressure dependent activation of leg muscles during standing following bed rest mimic those observed with ageing by Malcom Tremblay, Da Xu, Ajay K. Verma, Nandu Goswami, Nandu Goswami, Andrew P. Blaber

“…Since inactivity and ageing are common causes of orthostatic intolerance, the HDBR results were compared with those from young and older individuals in a previously published study to investigate the similarities in their effects on muscle-pump baroreflex.ResultsDuring standing, FTA reduced for all muscles except MG following HDBR and was lower in older compared to younger participants. …”
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Improving retention of pediatric feeding tubes with a nasal bridle: a randomized controlled trial by Megan Foster, Veronica Armijo-Garcia, Jonathan Gelfond, Andrew D. Meyer

“…Results A total of 35 patients were randomized and equally split to the bridle (n = 17) and tape arm (n = 18). The primary analysis revealed the rate of feeding tube dislodgement over 30 days was significantly higher in the tape group compared to the bridle group with an attributable risk reduction of 57% (hazard ratio = 6.3, 95% CI 2.4–16.5, p < 0.001). …”
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Evaluating the completeness of electronic health records in dental education: a big data study by Tamanna Tiwari, Maxim Kondratenko, Nihmath Nasiha, Toan Ong, Sangeetha Chandrasekaran, Gary Kostbade, Zachary Giano

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Combination of Diane-35 and Cangfu Daotan Wan Effectively Ameliorates Inflammatory Response, Stress State, and Hormone Levels in Patients with Polycystic Ovary Syndrome (PCOS), Lea... by Chen L, Fang CP, Chen Y, Gu WH, Wang SL, Niu N, Zhang QH

“…Comparisons were made between the two groups regarding inflammatory markers, stress response indicators, hormone levels, and overall treatment efficacy.Results: Post-treatment, the study group exhibited a lower incidence of polycystic ovarian changes and a higher overall efficacy rate compared to the control group (P&lt; 0.05). …”
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Comprehensive dosimetric comparison of halcyon 3.0 versus truebeam for breast cancer volumetric modulated arc therapy plans by Anyan Gu, Mengyuan Wang, Zhenyu Pan, Ran Tang, Yaotao Li, Yu Wu, Guozi Yang, Xingru Sun

“…BackgroundBreast cancer is the foremost malignancy threatening female health. This study aimed to compare the dosimetric performance of Halcyon 3.0 and TrueBeam in Volumetric Modulated Arc Therapy (VMAT) planning for breast cancer.MethodsThirty post-operative breast cancer patients were included. …”
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A novel technique for posterior internal fixation of acetabular fractures by Ming Li, Jingwei Xiao, Dian Wang, Fangzhu Xu

“…Methods A retrospective analysis of 155 patients with complete follow-up data from December 2014 to December 2020 was conducted. …”
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Exploration of Some Nutrient Absorption–Related Genes and Intestinal Histology in Japanese Quails (Coturnix japonica) Throughout Their Productive Lifespan by Hamid Reza Rafieian‐Naeini, Mahdi Zhandi, Maryam Taghipour‐Shahbandi, Amir Reza Sabzian, Ali Reza Yousefi, Mahboubeh Khajehnabi, Woo Kyun Kim

“…Methods A total of 135 quails from a commercial flock at different egg production periods (early production [EP, 6 weeks of age], pick production [PP, 21 weeks of age] and post pick production [PPP, 40 weeks of age]) were randomly selected (n = 45/group) and kept for 6 weeks. …”
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The impact of the COVID-19 pandemic on the surgical care continuum in Ethiopia: a national survey by Amare Hailekiros Gebregzi, Berhane Redae Meshesha, Hassen Mohammed Beshir, Desalegn Bekele Taye, Fitalew Dagnew, Manuel K. Sibhatu, Amanuel Sisay Endeshaw, Fantahun Tarekegn Kumie

“…During the post-pandemic year, there is a clinically significant delay in surgical admission for referral, general and primary hospitals. …”
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Comparison of the efficacy of laparoscopic primary closure of the common bile duct and T-tube drainage in the treatment of choledocholithiasis in elderly patients by Xiaofan Hua, Gang Wang, Bin Li, Genhai Shen, Wei Liu

“…The preoperative characteristics, intraoperative outcomes, and postoperative recovery of the PC and TD groups were compared. Results The PC group had shorter operative time, common bile duct suture time, bowel function recovery time, 6-day postoperative VAS, total hospital stay, and postoperative hospital stay compared to the TD group. …”
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Patient Reported Outcomes from an Open Label, Multi-Center, Retrospective Study of a Biodegradable Graft for Soft Tissue Reconstruction in Patients Suffering from Chronic Lateral A... by Bryan G. Vopat MD, Ryan Scott DPM

“…Surgical repair of the ATFL has relatively high success rates, however post-procedure chronic instability and pain remain a clinical challenge, with re-operation rates reported up to 14% (3). …”
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Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis by Junya Sato, Kazunari Nakahara, Ryo Morita, Nozomi Morita, Keigo Suetani, Yosuke Michikawa, Shinjiro Kobayashi, Fumio Itoh

“…The complication rate in early ERCP was 11.5% in the removal group and 10.1% in the drainage group, with no significant difference (P = 0.963). On comparing patients who underwent early endoscopic sphincterotomy (EST) with those who underwent elective EST after cholangitis had improved, the post-EST bleeding rates were 6.8% and 2.7%, respectively, with no significant difference (P = 0.600). …”
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Healthcare utilization and related costs among older people seeking primary care due to back pain: findings from the BACE-N cohort study by Danielle van der Windt, Milada Cvancarova Småstuen, Kjersti Storheim, Margreth Grotle, Zinajda Zolic-Karlsson, Ørjan Nesse Vigdal, Rikke Munk Killingmo, Lise Kretz

“…Healthcare utilization across patients with different SBST risk profiles was compared using Kruskal-Wallis test, post hoc Mann-Whitney U tests and Bonferroni adjustment.Results In total, 438 patients were included in the analysis. …”
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A Novel Approach to Strengthening the Microtensile Bond Between Lithium Disilicate Ceramics Manufactured by CAD/CAM and Dentin Using Coatings of Natural and Synthetic Bio-Modifiers by Abdulellah Almudahi, Abdullah Alshehri, Ali R. Alqahtani, Basil Almutairi, Ali A. Elkaffas, Refal Saad Albaijan, Mohammed Ali Abuelqomsan

“…Microtensile bond strength and interfacial nanoleakage were accessed after thermomechanical cyclic loading. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s post hoc test. …”
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Induced After-Death Communication (IADC) Therapy: An Effective and Quick Intervention to Cope with Grief by Fabio D’Antoni, Irene Pulvirenti, Antonella D’Orlando, Vilma Claudio, Claudio Lalla

“…Methods: This study employed a prospective observational cohort design with a retrospective analysis, comparing the effectiveness of IADC therapy (experimental group, <i>n</i> = 42) to standard grief interventions combining talk therapy and EMDR (control group, <i>n</i> = 43). …”
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Prognostic value of multi-PLD ASL radiomics in acute ischemic stroke by Zhenyu Wang, Yuan Shen, Xianxian Zhang, Qingqing Li, Congsong Dong, Shu Wang, Haihua Sun, Mingzhu Chen, Xiaolu Xu, Pinglei Pan, Pinglei Pan, Zhenyu Dai, Fei Chen, Fei Chen

“…Statistical analysis using the DeLong test revealed its significant outperformance compared to both the clinical model (AUC = 0.658, p &lt; 0.001) and the CBF radiomics model (AUC = 0.755, p = 0.002). …”
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全基因组关联分析标准化流程的构建与扩展应用(Development and Extended Applications of Standardized Processes for Genome-Wide Association Studies) by 许喆1，2，石延枫1，2，张杰1，2，姜明慧1，2，刘阳1，2，李昊1，2，3，廖晓凌4，程丝1，2，3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)

“…In the multi-omics analysis module, standardized analysis processes including polygenic risk score, meta-analysis, Mendelian randomization, and colocalization analysis were developed to enable in-depth exploration of GWAS results. …”
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Gestational diabetes-combined excess weight gain exacerbates gut microbiota dysbiosis in newborns, associated with reduced abundance of Clostridium, Coriobacteriaceae, and Collinse... by Yunshan Xiao, Yunshan Xiao, Yunshan Xiao, Yuan Shi, Yuan Shi, Yuan Shi, Yan Ni, Meilan Ni, Yuxin Yang, Xueqin Zhang, Xueqin Zhang, Xueqin Zhang

“…Statistical analyses explored correlations between total GWG/BMI gain and those before/after GDM diagnosis (t-GWG/GBG; b-GWG/GBG; a-GWG/GBG) with key bacterial taxa.ResultsNotable genus-level changes included enrichment of Escherichia and Klebsiella, and depletion of Bacteroides, Bifidobacterium, Coprococcus, Ruminococcus among GDM-Total and GDM+EGWG groups compared to non-GDM. Further,LEfSe analysis identified 30 differential bacteria taxa between GDM-Total and healthy control groups, which increased to 38 between GDM+EGWG and non-GDM groups, highlighting more pronounced microbial shifts associated with EGWG. …”
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The influence of dental occlusion on hamstring muscle isokinetic parameters in active competitive soccer athletes: a randomized controlled trial by Stine Hecht, Yoon Jeong Choi, Andrea Stroux, Florian Beuer, Manja von Stein-Lausnitz, Till E. Bechtold

“…A unilateral punctual malocclusion (MO) made of light-curing methacrylate was individually placed in region 16. Statistical analysis was performed with one-factorial analysis of variance (ANOVA) followed by post hoc pairwise comparison.ResultsThere was a significant decrease in maximum torque (Nm) and muscle work (J) during extension movement with the simulated MO is compared to HO and to HS. …”
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Etiological shifts and clinical outcomes of acute pancreatitis between urban and rural areas: evidence from a 20-year retrospective database by Ximei Cao, Ximei Cao, Zide Liu, Jingwen Rao, Jie Wu, Xin Huang, Liang Xia, Lingyu Luo, Xu Shu, Yin Zhu, Nonghua Lu, Wenhua He

“…Patients were stratified into urban (n = 5,002) and rural (n = 7,212) groups based on residential location. We compared demographic characteristics, etiological distributions, disease severity, complications, and hospitalization outcomes between the groups. …”
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Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach by Wen-Di Wang, Xin-Yi Fan, Xiao-Qi Wei, Wang-Jing Chai, Fang-He Li, Kuo Gao, Bin Liu, Bin Liu, Shu-Zhen Guo

“…Network pharmacology analysis and experimental validation revealed the components that protected H9c2 cells and reduced lactate dehydrogenase levels. …”
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