Sealing ability of the single-cone obturation technique with bioceramic sealer iRoot SP in oval root canals: an in vitro study by Qiaoyun Zhang, Xinhui Meng, Jiyuan Zhan, Lijun Huo, Yayan Lei

“…Statistical analyses were conducted using one-way analysis of variance and post hoc Tukey’s test with a significance threshold of 5%. …”
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Oral Anticoagulation Choice and Dosage in Very Elderly Patients with Atrial Fibrillation by Martha Zergioti, Melina Kyriakou, Andreas S. Papazoglou, Anastasios Kartas, Dimitrios V. Moysidis, Athanasios Samaras, Efstratios Karagiannidis, Vasileios Kamperidis, Antonios Ziakas, George Giannakoulas

“…Methods: This post hoc analysis of the MISOAC-AF trial focused on hospitalized AF patients aged ≥ 75 years prescribed OAC at discharge. …”
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Changes in Respiratory Sensitivity Status of Patients in a Hospital in Shanxi Province Before and After the COVID-19 Epidemic by Dong C, Hu F, Ma Z, Ma X, Zhang L, Li Y, Du X, Feng L, Huo R, Xing Y, Li P, Dong Y, Cheng E, Tian X, Huang M

“…And the high allergy season from July to September each year.Purpose: To investigate the effect of the COVID-19 epidemic on the respiratory sensitivity status of the population, to provide a scientific and effective basis for the prevention, diagnosis, condition assessment, and treatment of allergic respiratory diseases.Methods: We collected 500 outpatient cases from Shanxi Medical University Second Hospital during the period from July to September 2022 and 500 cases during the period from July to September 2023 and divided them into the pre-COVID-19 epidemic group (the 2022 group) and the post-COVID-19 epidemic group (the 2023 group). We conducted statistical analysis on these patients’ general conditions, pulmonary function test results, laboratory parameters, and fractional exhaled nitric oxide.Results: Compared with 2022, the number of smokers decreased in 2023 (p = 0.007), while the incidence of respiratory allergic diseases such as bronchial asthma and allergic rhinitis increased (p < 0.05). …”
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In vivo and in situ evaluation of innovative approaches in dentin hypersensitivity treatment by Heba Abd El-Fattah Mohamed, Dina Ezzeldin Mohamed, Elhassan Hassanein, Heba El-din Salah El-din Hamza

“…The in-situ phase evaluated dentinal tubules occlusion pre- and post-treatment using scanning electron microscopy (SEM) at 2000× magnification. …”
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Unveiling the dual threat: combined elevated triglyceride-glucose index and intracranial arterial stenosis burden for enhanced stroke risk stratification by Baoyi Liao, Baoyi Liao, Guilin Meng, Guilin Meng, Xueyuan Liu, Xueyuan Liu

“…Mechanistic pathways were delineated through causal mediation analysis employing Quasi-Bayesian approximation (100 Monte Carlo simulations) to quantify mediating effects between metabolic dysfunction and cerebrovascular outcomes.ConclusionThe synergistic combination of elevated TyG index and ICAS burden demonstrated superior prognostic value for 3-month stroke recurrence risk compared to either parameter independently, suggesting that concurrent assessment of insulin resistance (via TyG index) and vascular imaging biomarkers (via ICAS burden) may refine early risk stratification. …”
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Gender Peculiarities of Postresuscitation in the Expression of Brain-Derived Neurotrophic Factor (BDNF) by M. Sh. Avrushchenko, I. V. Ostrova, A. V. Grechko

“…Gender-specific patterns of brain damage and their importance for understanding the mechanisms of post-hypoxic encephalopathies are discussed.…”
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TWO DECADES OF ARCHAEOLOGICAL RESEARCH IN THE SOUTHERN DISTRICT OF THE CITY OF TROPAEUM TRAIANI (4th-6th CENTURIES AD.) AND OTHER DISCOVERIES. MAJOR SCIENTIFIC RESULTS by Gabriel Mircea TALMAȚCHI

“…Analysis of various aspects of everyday life, specific to the Roman world during the time of Constantine and post-Constantine in provincial territories, includes also the civil architecture. …”
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Unilateral Dual‐Plane Puncture Percutaneous Vertebroplasty Reduces Re‐Collapse in Osteoporotic Vertebral Compression Fractures by Advancing Cement Delivery by Huo‐Liang Zheng, Chang‐hai Liu, Lei‐Sheng Jiang, Xin‐Feng Zheng, Sheng‐Dan Jiang

“…This contributed to a significant reduction in the incidence of vertebral re‐collapse within the first year post‐operation: 18.92% in the unilateral dual‐plane group as opposed to 42.25% in the traditional group (p < 0.001). …”
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The Robust Vessel Segmentation and Centerline Extraction: One-Stage Deep Learning Approach by Rostislav Epifanov, Yana Fedotova, Savely Dyachuk, Alexandr Gostev, Andrei Karpenko, Rustam Mullyadzhanov

“…The proposed end-to-end framework directly predicts the centerline as a polyline with real-valued coordinates, thereby eliminating the need for post-processing steps commonly required by previous methods that infer centerlines either implicitly or without ensuring point connectivity. …”
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The first-line therapy of aggressive non-Hodgkin’s lymphomas in russian clinical practice: data from the EQUILIBRIUM study by L. G. Babicheva, I. V. Poddubnaya

“…Available and compliant with national clinical guidelines treatment of aNHL patients with Russian bioanalogue of anti-CD20 monoclonal antibodies (Acellbia®) demonstrates high immediate efficacy and acceptable long-term results, comparable to a retrospective analysis of previous clinical studies of the original drug rituximab.…”
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Proteomic Profiling of COVID-19 Patients Sera: Differential Expression with Varying Disease Stage and Potential Biomarkers by Iman Dandachi, Ayodele Alaiya, Zakia Shinwari, Basma Abbas, Alaa Karkashan, Ahod Al-Amari, Waleed Aljabr

“…Our study also gave insights about specific proteins that are likely increased upon infection but are likely restored post recovery.…”
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Evaluation of early donor renal function recovery after living-donor nephrectomy as a predictor of allograft failure after kidney transplantation: a longitudinal cohort and machine... by Saifu Yin, Xing Li, Chengze Liang, Rong Bao, Jun Zeng, Ming Ma, Mengli Zhu, Xianding Wang, Lijuan Wu, Turun Song, Tao Lin

“…This association persisted across pre-donation eGFR and post-donation eGFR (<90 vs. ≥ 90 mL/min/1.73 m2). …”
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The Effect of Antioxidant Administration on Semen Quality in Men with Infertility: A Randomized Placebo-Controlled Clinical Trial by Pinelopi Ioannidou, Theodosia Zeginiadou, Christos Venetis, Dimitrios Papanikolaou, Leonidas Zepiridis, Despoina Savvaidou, Katerina Chatzimeletiou, Alexandros Lambropoulos, Dimitrios G. Goulis, Grigoris Grimbizis, Efstratios M. Kolibianakis

“…The values of primary and secondary outcomes between treatment initiation and treatment completion were compared within groups. Moreover, their changes between treatment initiation and treatment completion were compared between the placebo- and the spermotrend-groups. …”
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Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

“…Testes were removed from all mice, and histomorphometry and flow cytometry analyses were performed 60 days post-treatment. Additionally, protein structure extraction, protein-protein docking analysis, and data visualization were conducted.Results: Histomorphometry and flow cytometry showed that most seminiferous tubules in the therapy groups exhibit­ed normal morphology and restored spermatogenesis, unlike the azoospermia group. …”
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Evaluating SARS-CoV-2 T Cell Immunity in COVID-19-Naive Vaccinated Individuals with and Without Spike Protein IgG Antibodies by Vassiliki C. Pitiriga, Myrto Papamentzelopoulou, Dimitris Nikoloudis, Chrysa Saldari, Kanella E. Konstantinakou, Irene V. Vasileiou, Athanasios Tsakris

“…No significant difference was observed between the two groups in the time period post vaccination, with the mean times after vaccination being 136.38 ± 78.68 days in group A and 140.6 ± 79.5 days in group B (T-test, <i>p</i> = 0.74). …”
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Effectiveness of ensitrelvir for cough caused by COVID-19 Omicron variant in patients with asthma by Naoyuki Miyashita, Nobuyuki Horita, Yasushi Nakamori, Makoto Ogata, Naoki Fukuda, Akihisa Yamura, Tomoki Ito

“…ABSTRACT In the post-acute coronavirus disease 2019 (COVID-19) period, patients with asthma had a significantly higher risk of cough than patients without a history of asthma. …”
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In-vitro and in-vivo assessment of biocompatibility and efficacy of ostrich eggshell membrane combined with platelet-rich plasma in Achilles tendon regeneration by Omid Koohi-Hosseinabadi, Reza Shahriarirad, Amireza Dehghanian, Laleh Amini, Sajjad Barzegar, Afrooz Daneshparvar, Omid Alavi, Seyedeh-Parvin Khazraei, Saba Hosseini, Ali Arabi Monfared, Roya Khorram, Nader Tanideh, Soheil Ashkani-Esfahani

“…The in vivo assay indicated that the ESM scaffold was safe for an extended period of 8 weeks, showing no signs of inflammation based on histopathological analysis. In the Achilles tendon rupture model, combining ESM with PRP enhanced tendon healing after 14 weeks post-surgery. …”
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Abstract 013: Infarct density: a novel imaging biomarker of long‐term functional outcome after endovascular thrombectomy by Christopher G. Favilla, Heta Patel, Mohammad Hossein Abassi, Jesse Thon, Michael T. Mullen, Scott E. Kasner, Jae W. Song, Stephanie Cummings, Steven R. Messe

“…A receiver operating characteristics (ROC) analysis was used to calculated areas under the curve (AUC) with 95% confidence intervals for the final model. …”
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Does Syndesmotic Fixation Technique Impact Complication Rates and Functional Outcomes Measured by PROMIS Scores Following Operative Repair of Ankle Fractures? by Steven Hadley BA, Rachel Bergman MD, John Peabody MD, Sarah Westvold MPH, Ryan Filler MD, Milap Patel DO, Anish Kadakia MD

“…The Kruskal-Wallis test compared PROMIS scores across repair types. Analysis of PROMIS scores had 80% power to detect large effect sizes (Cohen’s f = 0.40) with a 0.05 significance level but was underpowered for small and medium effects. …”
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Proximal femur replacement in oncologic lesion: hemiarthroplasty vs total hip arthroplasty—a multicentric retrospective study by Matteo Salvini, Giuseppe Malerba, Cesare Meschini, Alessandro El Motassime, Edoardo Venturini, Domenico Andrea Campanacci, Francesco Muratori, Simone Checcucci, Roberto Scanferla, Raffaele Vitiello, Giulio Maccauro

“…Outcomes were appraised utilizing the Harris Hip Score (HHS) and the Musculoskeletal Tumor Society (MSTS) score at three months post-surgery. Furthermore, the study assessed the rates of complications. …”
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