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  1. 641

    A post-marketing pharmacovigilance study of triazole antifungals: adverse event data mining and analysis based on the FDA adverse event reporting system database by Yalan Tian, Min Jin, Hong Ning

    Published 2025-01-01
    “…BackgroundTo explore and analyze post-marketing adverse drug event (ADE) signals for voriconazole, posaconazole, and isavuconazole, and to compare the safety differences among the three drugs, aiming to provide insights for rational clinical use.MethodsUsing the Open Vigil 2.1 online tool, extract adverse drug event (ADE) report data for voriconazole, posaconazole, and isavuconazole from the U.S. …”
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  2. 642

    Switching from Dupilumab to Abrocitinib in Patients With Moderate-to-Severe Atopic Dermatitis: A Post Hoc Analysis of Efficacy After Treatment With Dupilumab in JADE DARE by Jonathan I. Silverberg, Eric L. Simpson, Andrew E. Pink, Stephan Weidinger, Gary Chan, Pinaki Biswas, Claire Clibborn, Erman Güler

    Published 2025-02-01
    “…Abstract Introduction Primary results of the JADE DARE trial (NCT04345367) demonstrated that abrocitinib was superior to dupilumab in reducing the signs and symptoms of moderate-to-severe atopic dermatitis (AD). This post hoc analysis evaluated the efficacy and safety of abrocitinib in patients with moderate-to-severe AD who were responders or nonresponders to dupilumab using various definitions of response. …”
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    Instrumented gait analysis post‐anterior cruciate ligament reconstruction in pediatric patients: A non‐invasive method for quantifying the static and dynamic leg axis by Leonie Kijewski, Eva Böker, Karoline Hofmann, Thomas Engel, Pierre Hepp, Maren Witt

    Published 2025-04-01
    “…Abstract Purpose This study explores the potential of Instrumented gait analysis (IGA) as a non‐invasive tool for monitoring rehabilitation in pediatric patients with anterior cruciate ligament (ACL) injuries. …”
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    Comparative analysis of tissue damage and inflammatory response for transoral laser microsurgery versus open surgery in the management of early-stage laryngeal cancer by Jingchun Ge, Jiawei Gui, Hui Xiao

    Published 2025-05-01
    “…Results There were no significant differences in baseline characteristics between the two groups. Analysis of clinical and perioperative data revealed that patients who underwent TLM experienced shorter operating times, reduced hospital stays, and lower estimated blood loss and Visual Analog Scale (VAS) scores compared to those in the OS group. …”
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  12. 652

    Time-Dependent Fragility Functions and Post-Earthquake Residual Seismic Performance for Existing Steel Frame Columns in Offshore Atmospheric Environment by Xiaohui Zhang, Xuran Zhao, Shansuo Zheng, Qian Yang

    Published 2025-07-01
    “…The evolution laws of the fragility parameters with increasing service age under each damage state are determined, and a time-dependent fragility model for existing steel frame columns in offshore atmospheric environments is presented through regression analysis. At a drift ratio of 4%, the probability of complete damage to columns with 40, 50, 60, and 70-year service ages increased by 18.1%, 45.3%, 79.2%, and 124.5%, respectively, compared with columns within a 30-year service age. …”
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    Comparative Transcriptomic Analysis Between High- and Low-Growth-Rate Meat-Type Rabbits Reveals Key Pathways Associated with Muscle Development by Chao Yang, Lingxi Zhu, Li Tang, Xiangyu Zhang, Min Lei, Xiaohong Xie, Cuixia Zhang, Dingsheng Yuan, Congyan Li, Ming Zhang

    Published 2025-05-01
    “…Subsequent, post-natal qualities of thigh and <i>longissimus dorsi</i> muscle fiber were quantified across three developmental phases (28, 56, and 84 days post-natal). …”
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