Comparison of observational methods to identify and characterize post-COVID syndrome in the Netherlands using electronic health records and questionnaires. by Isabelle Bos, Lisa Bosman, Rinske van den Hoek, Willemijn van Waarden, Matthijs S Berends, Maarten S Homburg, Tim Olde Hartman, Jean Muris, Lilian S Peters, Bart Knottnerus, Karin S Hek, Robert A Verheij

“…In the GP-EHR data, we operationalized two classifications of PCS (based on symptoms and diagnosis recorded in GP-EHR data and healthcare utilization 3-12 months after acute infection) to calculate frequency and characteristics and compared this to the survey results. …”
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Virtual Imaginative Geographies: Generative AI and the Representation of Landscape Imagery by Ghieth Alkhateeb, Joanna Storie, Simon Bell, Monika Suškevičs

“…To address the bias challenges, the research presents the following four key recommendations for future research and practice: (1) incorporating finer-scale ecosystem classifications; (2) diversifying training datasets; (3) engaging local communities in participatory data collection; and (4) refining prompt-writing methodologies. …”
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Efficacy and safety of PD-1/PD-L1 inhibitors as first-line treatment for esophageal squamous cell carcinoma: a systematic review and meta-analysis by Wei Ren, Hanyu Zhang, Yixin Li, Wu Sun, Hexiang Peng, Huangda Guo, Tianjiao Hou, Mengying Wang, Mengying Wang, Zhendong Hu, Tao Wu, Tao Wu, Baorui Liu

“…PurposeThis study aims to investigate the efficacy and safety of PD-1/PD-L1 inhibitors in the first-line treatment of esophageal squamous cell carcinoma (ESCC) and identify factors influencing efficacy through a meta-analysis of multiple phase 3 randomized controlled trials (RCTs).MethodsA systematic literature search was conducted in Cochrane, PubMed, and Embase databases. …”
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The transhiatal tunnel valvuloplasty technique following laparoscopic proximal gastrectomy: the single-center experience in a retrospective cohort by Chunguang Guo, Zefeng Li, Xin Guo, Yong Liu, Dong Qu, Zhaodong Xing, Hu Ren, Chongyuan Sun, He Fei, Xiaojie Zhang, Lei Ge, Yanwei Gao, Enjun Li, Chaodong Yin, Jing Zhang, Guiqi Wang, Dongbing Zhao

“…No patients reported severe reflux symptoms (Visick score ≥III). Gastroscopy confirmed reflux esophagitis (Los Angeles classification Grade A) in one patient, and an anastomotic stricture requiring endoscopic balloon dilation was observed in another patient. …”
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Evolution analysis of sweet osmanthus (Osmanthus fragrans) cultivars based on sequence-related amplified polymorphism molecular marker by QIU Shuai, WU Guanghong, CHEN Xuping, GUO Juan, WEI Jianfen, SHEN Baichun, HU Shaoqing

“…Nei’s genetic diversity index ranged from 0.220 3 to 0.350 2, with an average of 0.283 5. The Shannon’s genetic diversity index ranged from 0.348 3 to 0.519 3, with an average of 0.436 4. …”
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Nutritional and immune-inflammatory scoring system for predicting outcomes in newly diagnosed diffuse large B-cell lymphoma patients by Yu Peng, Tingting Jiang, Shuang Chen, Xinyi Tang, Xinyi Tang, Yakun Zhang, Yakun Zhang, Liangmei Li, Lian Li, Longrong Ran, Xuelian Wu, Jun Li, Wei Zhang, Nanjun Li, Zailin Yang, Yao Liu

“…DLBCL patients with a high NII (≥ 6) exhibit significantly adverse clinical features, including older age, lower frequency of the non-GCB subtype, advanced Ann Arbor stage (III/IV), poor performance status (ECOG PS ≥ 2), involvement of ≥ 2 extranodal sites, presence of B symptoms, elevated lactate dehydrogenase (LDH) levels, and classification into higher-risk groups according to IPI and NCCN-IPI. …”
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Can Ileostomy Reversal Be Safely Performed by Surgical Residents? by Michał Kisielewski, Magdalena Pisarska-Adamczyk, Natalia Dowgiałło-Gornowicz, Łukasz Nawacki, Wojciech Serednicki, Mateusz Wierdak, Jerzy Wilczek, Kamil Safiejko, Marcin Juchimiuk, Marian Domurat, Jacek Pierko, Mateusz Mucha, Wojciech Fiedorowicz, Michał Wysocki, Maurycy Ladziński, Michał Zdrojewski, Tomasz Sachańbiński, Tomasz Wojewoda, Victoria Chochla, Karol Tkaczyński, Michał Jankowski, Wojciech M. Wysocki

“…The 30-day reoperation rate was 3.3% in the resident group and 8.6% in the specialist surgeon group (<i>p</i> = 0.179). …”
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The Nutritional Phenotyping of Idiopathic Pulmonary Fibrosis Through Morphofunctional Assessment: A Bicentric Cross-Sectional Case–Control Study by Alicia Sanmartín-Sánchez, Rocío Fernández-Jiménez, Eva Cabrera-César, Francisco Espíldora-Hernández, Isabel Vegas-Aguilar, María del Mar Amaya-Campos, Fiorella Ximena Palmas-Candia, Josefina Olivares-Alcolea, Víctor José Simón-Frapolli, Isabel Cornejo-Pareja, Ana Sánchez-García, Mora Murri, Patricia Guirado-Peláez, Álvaro Vidal-Suárez, Lourdes Garrido-Sánchez, Francisco J. Tinahones, Jose Luis Velasco-Garrido, Jose Manuel García-Almeida

“…CT-T12 BC parameters were analyzed using FocusedON^® software, while statistical analyses were conducted with JAMOVI version 2.3.22. All four major nutritional phenotypes were represented in our cohort, with significant overlap. …”
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Studying the dynamics of crowd panic propagation during emergency evacuation by Yushan Li, Changchun Liu, Yi Yang

“…The population was classified into three categories—staff, caregivers, and patients—and the effect of the ratio of these categories on evacuation efficiency was examined. …”
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Evolutionary Prediction of Nonstationary Event Popularity Dynamics of Weibo Social Network Using Time-Series Characteristics by Xiaoliang Chen, Xiang Lan, Jihong Wan, Peng Lu, Ming Yang

“…Third, the explanatory compensation variable social intensity (SI) is introduced to optimize the model N-SEP2M. Experiments on three Weibo hot events with different subject classifications show that our prediction approach is effective for the propagation of hot events with burst traffic.…”
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Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study by Iain B McInnes, Stefan Siebert, Arthur Pratt, Andrew Filer, Karim Raza, Wan-Fai Ng, Christopher D Buckley, Dawn Teare, Andrew Melville, Amy Anderson, Andrew McGucken, Bernard Dyke, Catharien M U Hilkens, John Isaacs, Kenneth F Baker, Mohadeseh Shojaei Shahrokhabadi, Shaun Hiu, Theophile Bigirumurame, Carl Goodyear, Fiona Rayner, Sean Kerrigan, Jonathan Prichard

“…Flare rate by week 24 was 52.3% (95% CI 43.0 to 61.7), with a median (IQR) time to flare of 63 (41–96) days. …”
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Impact of point‐of‐care maternal viral load testing at delivery on vertical HIV transmission risk assessment and neonatal prophylaxis: a cluster randomized trial by Anange Fred Lwilla, Kira Elsbernd, Siriel Boniface, Raphael Edom, Arlete Mahumane, Bindiya Meggi, W. Chris Buck, Joaquim Lequechane, Kassia Pereira, Nhamo Chiwerengo, Falume Chale, Chishamiso Mudenyanga, Dadirayi Mutsaka, Marianna Mueller, Nyanda E. Ntinginya, Nuno Taveira, Michael Hoelscher, Ilesh Jani, Arne Kroidl, Issa Sabi, and the LIFE Study Consortium

“…Results A total of 6467 WLWH were enrolled: 66.3% were diagnosed before the third trimester, 99% were on antiretroviral therapy and 78% were virally suppressed at delivery. …”
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Using ultrasound to define inflammatory and non-inflammatory phenotypes in difficult-to-treat psoriatic arthritis by Ennio Lubrano, Alen Zabotti, Ivan Giovannini, Luca Quartuccio, Fabio Massimo Perrotta, Andrea Di Matteo, Gabriele De Marco, Dennis McGonagle, Maria De Martino, Miriam Isola, Nicola Cabas, Cristina Di Nicola, Andrea Guiotto, Nicoletta Franzolini

“…The MSUS showed higher ultrasound activity (3.81±2.0 vs 0.91±0.5, p&lt;0.001) and greater structural damage (4.12±1.0 vs 2.38±2.1, p&lt;0.001), with both activity and damage scores being higher in PIPsA patients.Conclusion The classification into PIPsA and NIPsA based on easily detectable clinical features can support a tailored therapeutic management of patients with D2T-PsA.…”
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Exploring Functional Connectivity in Chronic Spinal Cord Injury Patients With Neuropathic Pain Versus Without Neuropathic Pain by Shreya Mandloi, Mashaal Syed, Isaiah Ailes, Omid Shoraka, Benjamin Leiby, Jingya Miao, Sara Thalheimer, Joshua Heller, Feroze B. Mohamed, Ashwini Sharan, James Harrop, Laura Krisa, Mahdi Alizadeh

“…Of the 10 SCI patients, 7 (48.6 ± 17.02 years old, 6 male and 1 female) indicated that they had NP and 3 did not have NP (39.33 ± 8.08 years old, 2 male and 1 female). …”
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Tumor-agnostic transcriptome-based classifier identifies spatial infiltration patterns of CD8+T cells in the tumor microenvironment and predicts clinical outcome in early-phase and... by Cláudia S Ferreira, Konstanty Korski, Michael A Cannarile, Irina Klaman, Petra C Schwalie, Iakov I Davydov, Andreas Roller, Martha L Serrano-Serrano, Astrid Heller, Nicolas Staedler, Gabriele Dietmann, Alberto Valdeolivas

“…Using regularized logistic regression, we developed an RNA-seq-based classifier as a surrogate to the IHC-based spatial classification of CD8+tumor-infiltrating lymphocytes in the TME.Results The CD8 immunophenotype and associated gene expression patterns varied across indications as well as across primary and metastatic lesions. …”
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Prognostic Impact of Klintrup–Mäkinen (KM) Score in Gastric Cancer and Its Association with Pathological Parameters by Andreea-Raluca Cozac-Szőke, Georgian-Nicolae Radu, Anca Negovan, Dan Alexandru Cozac, Sabin Turdean, Andreea-Cătălina Tinca, Emőke-Andrea Szász, Iuliu-Gabriel Cocuz, Adrian-Horațiu Sabău, Raluca Niculescu, Diana Maria Chiorean, Alexandru Nicușor Tomuț, Ovidiu Simion Cotoi

“…Patients with low KM grades demonstrated significantly more aggressive tumor features, including a higher prevalence of Borrmann classification types III-IV (75.8% vs. 54.9%, <i>p</i> = 0.01), poorly differentiated histology (74.1% vs. 33.8%, <i>p</i> < 0.0001), advanced T stage (93.5% vs. 80.2%, <i>p</i> = 0.04), and lymph node involvement (87% vs. 60.5%, <i>p</i> = 0.0008). …”
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Clinical Trial Risk in Hepatitis C: Endpoint Selection and Drug Action by Nicole A. Tillie, Jayson L. Parker, Jordan J. Feld

“…One hundred and twenty-three unique drug compounds were found to fulfill the inclusion criteria, eight of which had FDA approval. …”
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Efficacy of initial combination with belimumab in newly diagnosed childhood-onset lupus nephritis: a single-centre historical control study by Yu Shi, Jing Chen, Hong Xu, Qian Shen, Yinv Gong, Li Sun, Qijiao Wei, Yifan Li, Xiaomei Zhang, Shuhua Liu, Haimei Liu, Wanzhen Guan, Qiaoqian Zeng, Qianying Lv

“…In the standard immunotherapy group, 4 patients (6.3%) experienced a decline in estimated glomerular filtration rate of 30% or more at 12 months, while no patients in the belimumab group experienced worsening of renal function. …”
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The Process of Public Decision Making: A Literature Review by Tülin Altun

“…This study examines the developments in the literature on public decision-making models throughout history and evaluates the relevant literature under three main headings by considering the effects of conditions such as changes in economic thought, political institutions, and governmental policies on these models. …”
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Findings and methodologies in oral phageome research: a systematic review by Xin Chen, Ting Zou, Guicong Ding, Shan Jiang

“…Evidence indicates that bacteriophages (phages) are widely present in the oral microbiome and exhibit diverse classifications and interactions with human cells and other microbes. …”
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