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  15. 27475

    Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas by Jingjing Miao, Boyu Chen, Lu Zhang, Zhongming Lu, Rui Wang, Chunyang Wang, Xingyu Jiang, Qi Shen, Yue Li, Dongni Shi, Ying Ouyang, Xiangfu Chen, Xiaowu Deng, Siyi Zhang, Hequn Zou, Shuwei Chen

    Published 2025-03-01
    “…Importantly, combined treatment with EFNB1-Fc and VEGFR3 inhibitor synergistic abrogated lymphangiogenesis in vitro and in vivo, suggesting that targeting EPHB2 might be a potential strategy to patients with no or slight response to VEGFR3 inhibitor. …”
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    Fasting plasma glucose outperformed 1-hour plasma glucose in predicting diabetes incidence in individuals with family history of young-onset type 2 diabetes by Juliana C N Chan, Ronald Ching Wan Ma, Alice Pik Shan Kong, Baoqi Fan, Eric S H Lau, Elaine Chow, Chun Kwan O, Andrea Luk, Jane PY Ho, Gary TC Ko, Juliana NM Lui

    Published 2025-06-01
    “…We examined the interaction between FmH-YOD and 1-hour PG in predicting diabetes and used receiver operating characteristics (ROC) analysis to compare the performance of 1-hour PG in participants with or without FmH-YOD.Results Among 583 participants (median age (IQR)=41 (36–47) years, 43.7% men, body mass index=23.3 (21.2–26) kg/m2, 40.3% (n=235) had FmH-YOD, 1-hour PG=8.1 (6.4–10.1) mmol/L), 99 (17%) had developed diabetes at a follow-up of 12.1 (11.3–13.1) years. …”
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  18. 27478

    The evaluation of performance for agroecological greenhouse tomato strategies by the CRITIC-OWA model by José Manuel Brotons-Martínez, José María Cámara-Zapata

    Published 2025-06-01
    “…To help in decision-making, the present work analyzes the sustainability of greenhouse tomato production with different agroecological strategies: shading (conventional fixed mesh and mobile photovoltaic shading), grafting and deficit irrigation, based on economic, social, and environmental criteria.MethodsFor the ranking of the different strategies, the use of an extension of the CRiteria Importance Through Inter-criteria Correlation (CRITIC) is proposed, in which the correlation between the criteria is obtained through the Pearson-OWA, where the aggregation of the quadratic differences between criteria is carried out considering the attitudinal character of the decision-maker, that is, using Ordered Weighted Averaging (OWA), in addition to induced variables, with the Induced Probabilistic OWA CRITIC (IPOWA CRITIC). Three extensions are considered based on this model depending on the way the multicriteria score is calculated: i) the ranking is carried out on the relative score (S) of each alternative (IPOWA-S-CRITIC), ii) on the weighting vector (W) (IPOWA-W-CRITIC), or iii) on both (IPOWA-S-W-CRITIC).ResultsThe results of the classifications conducted indicate that the use of mobile photovoltaic mesh is a sustainable production strategy, due to its effect on production and quality of the crop, CO2 fixation, and irrigation water savings.DiscussionThe use of mobile photovoltaic shades is compatible with tomato cultivation in a greenhouse if the management of the installation is performed considering the needs of the plants in most of the rankings.…”
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    The Continuity of Students’ Disengaged Responding in Low-stakes Assessments: Evidence from Response Times by Hatice Cigdem Bulut

    Published 2021-09-01
    “…To investigate the impact of filtering disengaged respondents on parameter estimation, three groups were created, namely engaged in both measures, engaged only in the test, and engaged only in the questionnaire. …”
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  20. 27480

    Analysis of the patients' quality of life after radical cystectomy with the orthotopic neobladder or ileal conduit formation by S. V. Kotov, A. L. Khachatryan, D. P. Kotova, A. K. Zhuravleva, Sh. M. Sargsyan, D. M. Magomedov

    Published 2021-03-01
    “…The frequency of complications according to Clavien-Dindo I - II in the Group 1 was observed in 11 (42.3%) patients, in the Group 2 in 12 (35.2%) patients (p = 0.579), complications according to Clavien-Dindo III - IV in the Group 1 were found in 5 (19.2%) patients while in the Group 2 in 7 (20.5%) patients (p = 0.896). …”
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